Sirtuin 3 Deficiency Is Associated with Inhibited Mitochondrial Function and Pulmonary Arterial Hypertension in Rodents and Humans

Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes

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Heart-Lung Transplantation

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Regulation of cellular metabolism by protein lysine acetylation

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A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth

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Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

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A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

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Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

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Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

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Mitochondrial Membrane Potential in Living Cells

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Recent advances in pulmonary arterial hypertension

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Drug repositioning in pulmonary arterial hypertension: challenges and opportunities

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Ageing and longevity genes in cardiovascular diseases

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Resveratrol Prevents Right Ventricle Dysfunction, Calcium Mishandling, and Energetic Failure via SIRT3 Stimulation in Pulmonary Arterial Hypertension

Bernal‐Ramírez, J., Silva‐Platas, C., Carlos Jerjes-Sánchez, D., Ramos-González, M. R., Vázquez‐Garza, E., Chapoy‐Villanueva, H., Ramírez‐Rivera, A., Zarain‐Herzberg, Á., Garcı́a, N., & García‐Rivas, G. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/9912434 · Cited by 32

SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension

Li, M., Plecitá‐Hlavatá, L., Dobrinskikh, E., McKeon, B. A., Gandjeva, A., Riddle, S. R., Laux, A., Prasad, R. R., Kumar, S., Tuder, R. M., et al. (2023) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2022-0360oc · Cited by 35

The Search for Disease-Modifying Therapies in Pulmonary Hypertension

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Emerging therapeutics in pulmonary hypertension

Hensley, M. K., Levine, A. R., Gladwin, M. T., & Lai, Y. (2018) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00259.2017 · Cited by 30

Redox Homeostasis in Cardiovascular Disease: The Role of Mitochondrial Sirtuins

Zullo, A., Guida, R., Sciarrillo, R., & Mancini, F. P. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.858330 · Cited by 30

Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation

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Proline and glucose metabolic reprogramming supports vascular endothelial and medial biomass in pulmonary arterial hypertension

Wertheim, B. M., Wang, R., Guillermier, C., Hütter, C. V. R., Oldham, W. M., Menche, J., Steinhauser, M. L., & Maron, B. A. (2023) · JCI Insight · doi:10.1172/jci.insight.163932 · Cited by 29

The Biological Bases of Group 2 Pulmonary Hypertension

Fernández, A. I., Yotti, R., González‐Mansilla, A., Mombiela, T., Gutiérrez, E., del Villar, C. P., Navas-Tejedor, P., Chazo, C., Martínez‐Legazpi, P., Fernández‐Avilés, F., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20235884 · Cited by 29

Nicotinamide riboside regulates inflammation and mitochondrial markers in AML12 hepatocytes

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Sirtuin 3 is essential for host defense against Mycobacterium abscessus infection through regulation of mitochondrial homeostasis

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Epigenetic Mechanisms as Emerging Therapeutic Targets and Microfluidic Chips Application in Pulmonary Arterial Hypertension

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CTRP3 promotes energy production by inducing mitochondrial ROS and up-expression of PGC-1α in vascular smooth muscle cells

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Dual ETA/ETB blockade with macitentan improves both vascular remodeling and angiogenesis in pulmonary arterial hypertension

Nadeau, V., Potus, F., Boucherat, O., Paradis, R., Tremblay, È., Iglarz, M., Paulin, R., Bonnet, S., & Provencher, S. (2017) · Pulmonary Circulation · doi:10.1177/2045893217741429 · Cited by 27

Novel Molecular Mechanisms Involved in the Medical Treatment of Pulmonary Arterial Hypertension

de Miguel, I. M., Cruz‐Utrilla, A., Oliver, E., & Subías, P. E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24044147 · Cited by 26

Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction

Jheng, J.-R., Bai, Y., Noda, K., Huot, J. R., Cook, T. G., Fisher, A. J., Chen, Y.-Y., Goncharov, D. A., Goncharova, E. A., Simon, M. A. M., et al. (2024) · Circulation · doi:10.1161/circulationaha.124.068624 · Cited by 26

Sirtuins in the Cardiovascular System: Potential Targets in Pediatric Cardiology

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Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases

Gomes, P., Leal, H., Mendes, A. F., Reis, F., & Cavadas, C. (2019) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2019.09.003 · Cited by 27

Single Mutation in the NFU1 Gene Metabolically Reprograms Pulmonary Artery Smooth Muscle Cells

James, J., Zemskova, M., Eccles, C. A., Varghese, M. V., Niihori, M., Barker, N. K., Luo, M., Mandarino, L. J., Langlais, P. R., Rafikova, O., et al. (2020) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.120.314655 · Cited by 26

Redox Biology in Pulmonary Arterial Hypertension (2013 Grover Conference Series)

Fessel, J. P., & West, J. D. (2015) · Pulmonary Circulation · doi:10.1086/683814 · Cited by 25

Metabolic Reprogramming and Redox Signaling in Pulmonary Hypertension

Plecitá‐Hlavatá, L., D’Alessandro, A., Kasmi, K. E., Li, M., Zhang, H., Ježek, P., & Stenmark, K. R. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-63245-2_14 · Cited by 26

Genetic and Functional Sequence Variants of the SIRT3 Gene Promoter in Myocardial Infarction

Yin, X., Pang, S., Huang, J. A., Cui, Y., & Yan, B. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153815 · Cited by 25

Roles of SIRT3 in aging and aging-related diseases

You, Y., & Wang, Z. (2025) · International Journal of Biological Sciences · doi:10.7150/ijbs.115518 · Cited by 26

Intrauterine Hypoxia and Epigenetic Programming in Lung Development and Disease

Tong, Y., Zhang, S., Riddle, S. R., Zhang, L., Song, R., & Yue, D. (2021) · Biomedicines · doi:10.3390/biomedicines9080944 · Cited by 24

New cases of Glucose-6-Phosphate Dehydrogenase deficiency in Pulmonary Arterial Hypertension

Kurdyukov, S., Eccles, C. A., Desai, A. A., Gonzalez‐Garay, M. L., Yuan, J. X. ‐., Garcia, J. G. N., Rafikova, O., & Rafikov, R. (2018) · PLoS ONE · doi:10.1371/journal.pone.0203493 · Cited by 24

SIRT3-mediated cardiac remodeling/repair following myocardial infarction

Mihanfar, A., Nejabati, H. R., Fattahi, A., Latifi, Z., Faridvand, Y., Pezeshkian, M., Jodati, A., Safaie, N., Afrasiabi, A., & Nouri, M. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.09.079 · Cited by 24

Molecular and Genetic Profiling for Precision Medicines in Pulmonary Arterial Hypertension

Fazal, S., Bisserier, M., & Hadri, L. (2021) · Cells · doi:10.3390/cells10030638 · Cited by 27

Signal Transduction during Metabolic and Inflammatory Reprogramming in Pulmonary Vascular Remodeling

Gomes, M. T., Bai, Y., Potje, S. R., Zhang, L., Lockett, A. D., & Machado, R. F. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052410 · Cited by 22

In vitro synergistic effects of natural human tumor necrosis factor and natural human interferon-alpha.

Naomoto, Y., Tanaka, N., Fuchimoto, S., & Orita, K. (1987) · PubMed · Cited by 22

Update on novel targets and potential treatment avenues in pulmonary hypertension

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The MFF-SIRT1/3 axis, regulated by miR-340-5p, restores mitochondrial homeostasis of hypoxia-induced pulmonary artery smooth muscle cells

Huang, C., Jiang, Z., Du, D., Zhang, Z., Liu, Y., & Li, Y. (2022) · Laboratory Investigation · doi:10.1038/s41374-022-00730-w · Cited by 18

Sirtuin 3 Therapy Attenuates Aging Expression, Oxidative Stress Parameters, and Neointimal Hyperplasia Formation in Vein Grafts

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Integrating epigenetics and metabolomics to advance treatments for pulmonary arterial hypertension

Ranasinghe, A. D. C. U., & Schwarz, M. A. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115245 · Cited by 17

‘There and Back Again’—Forward Genetics and Reverse Phenotyping in Pulmonary Arterial Hypertension

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SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes

Zhang, Y., Zervopoulos, S. D., Boukouris, A. E., Carrillo, M. A. L., Saleme, B., Webster, L., Liu, Y., Haromy, A., Dakhili, S. A. T., Ussher, J. R., et al. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.020451 · Cited by 17

Metabolism and Redox in Pulmonary Vascular Physiology and Pathophysiology

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Liver-specific overexpression of SIRT3 enhances oxidative metabolism, but does not impact metabolic defects induced by high fat feeding in mice

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Mitochondrial cardiovascular diseases: molecular mechanisms, multi-omics exploration and therapeutic strategies

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Common Variation in EDN1 Regulatory Regions Highlights the Role of PPARγ as a Key Regulator of Endothelin in vitro

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The effects of lipoic acid on respiratory diseases

Guo, X., Wu, S., Shang, J., Dong, W., Li, Y., Peng, Q., Xie, Z., & Chen, C. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.109713 · Cited by 13

Idiopathic and connective tissue disease-associated pulmonary arterial hypertension (PAH): Similarities, differences and the role of autoimmunity

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Exploring the pathogenesis of pulmonary vascular disease

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Mitochondria as a primary determinant of angiogenic modality in pulmonary arterial hypertension

Niihori, M., James, J., Varghese, M. V., McClain, N., Lawal, O., Philip, R. C., Baggett, B. K., Goncharov, D. A., Pérez, V. D. J., Goncharova, E. A., et al. (2024) · The Journal of Experimental Medicine · doi:10.1084/jem.20231568 · Cited by 13

Sirtuins, Healthspan, and Longevity in Mammals

Giblin, W., & Lombard, D. B. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-411596-5.00003-4 · Cited by 12

Mitochondria at the crossroads of aging and cardiovascular disease

Lateef, O. M., Fakorede, S., Harris, C., Lateef, A. M., & Ajayi, A. F. (2025) · Life Sciences · doi:10.1016/j.lfs.2025.124127 · Cited by 11

The role of endothelial cells in pulmonary hypertension: old concepts and new science

Haensel, M., & Wójciak‐Stothard, B. (2023) · Current Opinion in Physiology · doi:10.1016/j.cophys.2023.100667 · Cited by 11

Potential Roles of Metals in the Pathogenesis of Pulmonary and Systemic Hypertension

Hopkins, C. D., Wessel, C. R., Chen, O., El‐Kersh, K., Cave, M. C., Cai, L. F., & Huang, J. (2023) · International Journal of Biological Sciences · doi:10.7150/ijbs.85590 · Cited by 11

Hemodynamic and Clinical Profiles of Pulmonary Arterial Hypertension Patients with GDF2 and BMPR2 Variants

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Stub1 Acetylation by CBP/p300 Attenuates Chronic Hypoxic-Driven Pulmonary Hypertension by Suppressing HIF-2α

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Pulmonary arterial hypertension: Cellular and molecular changes in the lung

Maron, B. A. (2020) · Global Cardiology Science and Practice · doi:10.21542/gcsp.2020.3 · Cited by 10

SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control

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Proteomics in Cardiovascular disease

Gong, M., Zhang, Y., Chen, N., Ma, L.-L., Feng, X.-M., & Yan, Y. (2024) · Clinica Chimica Acta · doi:10.1016/j.cca.2024.117877 · Cited by 8

Plasma Proteomics Identifies B2M as a Regulator of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction

Jheng, J.-R., DesJardin, J. T., Chen, Y.-Y., Huot, J. R., Bai, Y., Cook, T. G., Hibbard, L. M., Rupp, J. M., Fisher, A. J., Zhang, Y., et al. (2024) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.123.320270 · Cited by 8

Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease

Crnković, S., Puthenparampil, H. T., Mulch, S., Biasin, V., Radic, N., Wilhelm, J., Bartkuhn, M., Rad, E. B., Wawrzen, A., Matzer, I., et al. (2025) · eLife · doi:10.7554/elife.98558.3 · Cited by 8

[Advances in molecular mechanism of vascular remodeling in pulmonary arterial hypertension].

Li, X., & Tong, X. (2019) · PubMed Central · doi:10.3785/j.issn.1008-9292.2019.02.15 · Cited by 8

Novel molecular insights and public omics data in pulmonary hypertension

López‐Crisosto, C., Arias‐Carrasco, R., Sepúlveda, P., Garrido‐Olivares, L., Maracaja‐Coutinho, V., Verdejo, H., Castro, P., & Lavandero, S. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2021.166200 · Cited by 8

Novel Pharmacological Targets for Pulmonary Arterial Hypertension

Klinger, J. R. (2021) · Comprehensive physiology · doi:10.1002/cphy.c200015 · Cited by 10

Application of Transcriptomics and Proteomics in Pulmonary Arterial Hypertension

Jiang, J., Liu, S., Yang, H., Lv, Y., Ma, P., Xu, Q., & Zhou, R. (2023) · Personalized Medicine · doi:10.2217/pme-2023-0020 · Cited by 6

SIRT3 deficiency increases mitochondrial oxidative stress and promotes migration of retinal pigment epithelial cells

Wang, J.-X., Yang, Y., & Li, W. (2021) · Experimental Biology and Medicine · doi:10.1177/1535370220976073 · Cited by 6

The Iron Paradigm of Pulmonary Arterial Hypertension

Sutendra, G., & Bonnet, S. (2015) · Circulation Research · doi:10.1161/circresaha.115.306440 · Cited by 6

Multidimensional study on mitochondrial dysfunction in pulmonary hypertension

Yuan, X.-T., Zhang, Y., Liu, Y., Guo, X., Jia, S., Xiong, X., Xiuying, S., & Jin, Z. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1716485 · Cited by 5

Sirtuins and chemokines as markers of replicative and induced senescence of human endotheliocytes

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Honokiol and Nicotinamide Adenine Dinucleotide Improve Exercise Endurance in Pulmonary Hypertensive Rats Through Increasing SIRT3 Function in Skeletal Muscle

Li, M., McKeon, B. A., Gu, S., Prasad, R. R., Zhang, H., Kumar, S., Riddle, S. R., Irwin, D. C., & Stenmark, K. R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252111600 · Cited by 4

Beyond the genome: challenges and potential for epigenetics-driven therapeutic approaches in pulmonary arterial hypertension

Hsu, J. Y., Major, J. L., Riching, A. S., Sen, R., Silva, J. P. D., & Bagchi, R. A. (2020) · Biochemistry and Cell Biology · doi:10.1139/bcb-2020-0039 · Cited by 4

Addressing Complexity in Pulmonary Hypertension

Paulin, R., & Michelakis, E. D. (2015) · Circulation Research · doi:10.1161/circresaha.115.305773 · Cited by 4

The dominant model analysis of Sirt3 genetic variants is associated with susceptibility to tuberculosis in a Chinese Han population

Wu, T., Jiao, L., Bai, H., Hu, X. L., Wang, M., Zhao, Z., Xue, H., & Ying, B. (2020) · Molecular Genetics and Genomics · doi:10.1007/s00438-020-01685-7 · Cited by 4

Sirtuin 3 and Uncouplin Protein 2, the Missing Link Between Genetics, Metabolism, and Pulmonary Arterial Hypertension

Lajoie, A. C., & Potus, F. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.121.023065 · Cited by 4

Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular diseasePreprint

Crnković, S., Puthenparampil, H. T., Mulch, S., Biasin, V., Radic, N., Wilhelm, J., Bartkuhn, M., Rad, E. B., Wawrzen, A., Matzer, I., et al. (2024) · eLife · doi:10.7554/elife.98558 · Cited by 4

Melatonin attenuates monocrotaline‐induced hepatic sinusoidal obstruction syndrome in rats via activation of Sirtuin‐3

Ren, X., Xu, K., Xu, J., & Mei, Q. (2023) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.23422 · Cited by 3

Changes in the Expression and the Role of Sirtuin 3 in Cancer Cells and in Cardiovascular Health and Disease

Özden, Ö., & Tural, K. (2018) · InTech eBooks · doi:10.5772/intechopen.71865 · Cited by 4

Sirtuins and Aging

Pukhalskaia, A. E., Kvetnoy, I. M., Linkova, N. S., Diatlova, A., Gutop, E. O., Kozlov, K. L., & Paltsev, M. A. (2023) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-023-01379-8 · Cited by 3

Enhancer of zeste homolog 2 (EZH2)-dependent sirtuin-3 determines sensitivity to glucose starvation in radioresistant head and neck cancer cells

Chang, H. W., Park, J. J., Lee, W. H., Kim, S. H., Lee, J. C., Nam, H. Y., Kim, M. R., Han, M. W., Lee, Y. S., Kim, S. Y., et al. (2023) · Cellular Signalling · doi:10.1016/j.cellsig.2023.111029 · Cited by 3

Sirtuins, healthspan, and longevity in mammals

Kumar, S., Giblin, W., & Lombard, D. B. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-815962-0.00005-6 · Cited by 2

Letter to the editor: Decreased SIRT3 expression is a good potential biomarker associated with diseases

Yu, W., & Sun, Y. T. (2015) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00829.2014 · Cited by 3

NAD_MCNN: Combining Protein Language Models and Multiwindow Convolutional Neural Networks for Deacetylase NAD + Binding Site Prediction

Le, V., Liu, Y., Chang, Y., Lee, Y., Lin, Y., Malik, M. S., & Ou, Y. (2025) · Chemical Biology & Drug Design · doi:10.1111/cbdd.70085 · Cited by 2

Animal Models of Systemic Sclerosis

Štorkánová, H., & Tomčík, M. (2017) · InTech eBooks · doi:10.5772/intechopen.68551 · Cited by 2

SUL-150 Limits Vascular Remodeling and Ventricular Failure in Pulmonary Arterial Hypertension

Jorna, L. M., Nakládal, D., van Heuveln, J. N., van der Feen, D. E., Hagdorn, Q. A. J., Bossers, G. P. L., van Oosten, A., Weij, M., Tkáčiková, Ľ., Tkáčiková, S., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157181 · Cited by 1

Extracellular vesicles in vascular diseases: pathological mechanisms and therapeutic application progress

Wang, Y., Zhou, Y., Wang, H., Li, K., Hao, Q., Li, P., Guan, L., Zhou, X., Gao, B., & Han, T. (2025) · Vessel Plus · doi:10.20517/2574-1209.2025.98 · Cited by 1

Frehmaglutin F and frehmaglutin H ameliorate hypoxy-induced PASMCs injury via SIRT3/HIF-1α/PKM2 signal pathway

Zhang, Y., Zeng, M., Guo, P., Zhang, Z., Chen, X., Li, X., Lian, Z., Weisheng, F. E. N. G., & Zheng, X. (2026) · Cytotechnology · doi:10.1007/s10616-026-00914-y · Cited by 1

Critical Contribution of Cardiac Myofibroblasts in Right Ventricular Failure and the Role of UCP2 SNPs in the Predisposition to RV Decompensation in Pulmonary Arterial Hypertension

Zhang, Y., Bonnet, S., Provencher, S., Piao, J., Haromy, A., Liu, Y., Zhao, Y.-Y., Breuils‐Bonnet, S., Lemay, S.-E. S., Bowles, D. E., et al. (2026) · Circulation · doi:10.1161/circulationaha.125.078674 · Cited by 1

Dynamin 2 Regulates Mitochondrial Mitotic Fission in Pulmonary Hypertension

Dasgupta, A., Chen, K., Wu, D., Yerramilli, V. S., Lima, P. D. A., Martin, A. Y., Bentley, R. E. T., Ott, B. P., Nandani, T., Mewburn, J. D., et al. (2026) · Circulation Research · doi:10.1161/circresaha.125.327028 · Cited by 1

SIRTUINS AND VASCULAR AGING

Chaulin, A. M., & Grigoryeva, J. (2020) · International Journal of Applied and Fundamental Research (Международный журнал прикладных и фундаментальных исследований) · doi:10.17513/mjpfi.13159 · Cited by 1

Genetische Diagnostik und molekulare Ansätze bei pulmonalarterieller Hypertonie

Eichstaedt, C. A., Bikou, O., Sommer, N., SCHERMULY, R. T., Pullamsetti, S. S., Weißmann, N., Harbaum, L., Tabeling, C., Wißmüller, M., Foris, V., et al. (2023) · Pneumologie · doi:10.1055/a-2145-4663 · Cited by 1

Pulmonary Hypertension

Saha, S., Majumdar, S., & Bhattacharyya, P. (2023) · Springer eBooks · doi:10.1007/978-981-99-3505-5_10 · Cited by 1

Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular diseasePreprint

Crnković, S., Puthenparampil, H. T., Mulch, S., Biasin, V., Wilhelm, J., Bartkuhn, M., Rad, E. B., Wawrzen, A., Matzer, I., Mitra, A., et al. (2024) · eLife · doi:10.7554/elife.98558.1 · Cited by 1

The Role of Sirtuin 6 in Maintaining Vascular Integrity

Leung, S. Z. (2016) · Scholarship@Western (Western University)

Evangelos Michelakis

Jansen, J. M. (2018) · Circulation Research · doi:10.1161/circresaha.118.314005

A Novel Association Between Primary Biliary Cholangitis and Idiopathic Pulmonary Arterial Hypertension

AN, J. W. (2020) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3-c3fw-vz10

Scope to develop sirtuins modulators as a therapy to attenuate cardiac complications

Bugga, P., & Banerjee, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814118-2.00018-5

MAGNETIC DEVICES IN GLASS APPARATUS. PART II

Gamisch, G., & Ruettiger, W. (1958) · OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)

A bad old day on acting's Everest

Montgomery, J. (1997) · TLS, the Times literary supplement/Times literary supplement on CD-ROM/TLS. Times literary supplement

Pathobiology of Pulmonary Hypertension

Chen, C.-N., Zhao, L., Rhodes, C. J., & Zhao, L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11658-7

Tea polyphenols stimulate mt bioenergetics in cardiometabolic diseases

Srividhya, R. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90256-4.00012-6

Boosting the Exhausted Vasculature—SIRT3 (to the) Rescue

Ljubojević-Holzer, S., & Crnković, S. (2023) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2023-0199ed

Pathogenesis of Pulmonary Arterial Hypertension

Ponticos, M., Lee, M. H., Holmes, A. M., & Tuder, R. M. (2024) · Springer eBooks · doi:10.1007/978-3-031-40658-4_27

eLife Assessment: Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease

Emoto, N. (2024) · eLife · doi:10.7554/elife.98558.1.sa2

Reviewer #2 (Public Review): Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease

(2024) · eLife · doi:10.7554/elife.98558.1.sa0

Reviewer #1 (Public Review): Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease

(2024) · eLife · doi:10.7554/elife.98558.1.sa1

Abstract 18830: Mitochondrial Suppression Due to Loss of Sirt3 Deacetylase Activity Causes Pulmonary Arterial Hypertension

Paulin, R., Dromparis, P., Sutendra, G., Provencher, S., Bonnet, S., & Michelakis, E. D. (2013) · Circulation · doi:10.1161/circ.128.suppl_22.a18830

Abstract 17011: Loss-of-function SIRT3 Single Nucleotide Polymorphisms in Patients With Pulmonary Arterial Hypertension (PAH): Insights into the Metabolic Basis of PAH

Gurtu, V., Paulin, R., Webster, L., PATERSON, I. S., Provencher, S., Bonnet, S., & Michelakis, E. D. (2013) · Circulation

Abstract 19386: The Mitochondrial Deacetylase Sirtuin 3 (sirt3) is Important in the Pathogenesis of Both Pulmonary Hypertension and Pulmonary Fibrosis: Potential for an “Overlap Syndrome” and a Common Therapy?

Paulin, R., Zang, H., Boukouris, A. E., Gurtu, V., Haromy, A., & Michelakis, E. D. (2015) · Circulation · doi:10.1161/circ.132.suppl_3.19386

Abstract 13575: Lack of Both Mitochondrial Proteins Sirt3 and Ucp2 in Mice Recapitulates Many Critical Features of Human Pulmonary Arterial Hypertension (PAH), Including Inflammatory Plexogenic Lesions, Supporting the Metabolic Theory of PAH

Zhang, Y., Zervopoulos, S. D., Boukouris, A. E., Saleme, B., Liu, Y., Haromy, A., Webster, L., Dakhili, S. A. T., Ussher, J. R., Sutendra, G., et al. (2020) · Circulation · doi:10.1161/circ.142.suppl_3.13575

SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension

Li, M., Plecitá‐Hlavatá, L., Dobrinskikh, E., McKeon, B. A., Gandjeva, A., Riddle, S. R., Laux, A., Prasad, R. R., Kumar, S., Tuder, R. M., et al. (2023) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2022-0360oc · Cited by 35