Beige adipocyte maintenance is regulated by autophagy-induced mitochondrial clearance

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4. Towards a Better Understanding of Beige Adipocyte Plasticity
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5. Loss of RUBCN/rubicon in adipocytes mediates the upregulation of autophagy to promote the fasting response
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6. Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity
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7. Adrenergic-Independent Signaling via CHRNA2 Regulates Beige Fat Activation
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8. The Adipose Organ Is a Unitary Structure in Mice and Humans
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9. Proteolytic rewiring of mitochondria by LONP1 directs cell identity switching of adipocytes
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10. Adipocyte Liver Kinase b1 Suppresses Beige Adipocyte Renaissance Through Class IIa Histone Deacetylase 4
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11. Role of autophagy in the regulation of adipose tissue biology
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12. Adipose tissue ageing: implications for metabolic health and lifespan
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13. Autophagy inhibition blunts PDGFRA adipose progenitors’ cell-autonomous fibrogenic response to high-fat diet
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14. Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes
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15. Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State
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16. Macrophage and Adipocyte Mitochondrial Dysfunction in Obesity-Induced Metabolic Diseases
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17. TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
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18. Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program
    Adı́lson Guilherme, Leslie A. Rowland, Nicole Wetoska, Emmanouela Tsagkaraki, Kaltinaitis B. Santos, Alexander H. Bedard, Felipe dos Santos Henriques, Mark Kelly, Sean Munroe, David J. Pedersen et al. · 2023 · Cell Reports
19. MicroRNAs as regulators of mitochondrial dysfunction and obesity
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20. Transient p53 inhibition sensitizes aged white adipose tissue for beige adipocyte recruitment by blocking mitophagy
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21. Thermogenic adipose tissue aging: Mechanisms and implications
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22. Age-dependent Pdgfrβ signaling drives adipocyte progenitor dysfunction to alter the beige adipogenic niche in male mice
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23. Imaging adipose tissue browning using the TSPO-18kDa tracer [18F]FEPPA
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24. Suppression of Brown Adipocyte Autophagy Improves Energy Metabolism by Regulating Mitochondrial Turnover
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25. Sesamin induces A549 cell mitophagy and mitochondrial apoptosis via a reactive oxygen species-mediated reduction in mitochondrial membrane potential
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26. Precision Nutrition to Activate Thermogenesis as a Complementary Approach to Target Obesity and Associated-Metabolic-Disorders
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27. Theobromine enhances the conversion of white adipocytes into beige adipocytes in a PPARγ activation-dependent manner
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28. Iron Homeostasis and Energy Metabolism in Obesity
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29. Thermogenic adipose tissue in energy regulation and metabolic health
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30. Regulation of autophagy by plant‐based polyphenols: A critical review of current advances in glucolipid metabolic diseases and food industry applications
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31. BNIP3-mediated mitophagy in macrophages regulates obesity-induced adipose tissue metaflammation
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32. Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes
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33. Genome-Wide Insights into the Development and Function of Thermogenic Adipocytes
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34. Adipocytes spectrum — From homeostasia to obesity and its associated pathology
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35. Autophagy regulates functional differentiation of mammary epithelial cells
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36. Inhibition of autophagy with chloroquine dysregulates mitochondrial quality control and energetics in adipocytes
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37. The Role of Adipocytes Recruited as Part of Tumor Microenvironment in Promoting Colorectal Cancer Metastases
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38. Severe Hyperprolactinemia Promotes Brown Adipose Tissue Whitening and Aggravates High Fat Diet Induced Metabolic Imbalance
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39. Dysfunctional Mitochondria Clearance in Situ: Mitophagy in Obesity and Diabetes-Associated Cardiometabolic Diseases
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40. Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice
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41. The regulation of TFEB in lipid homeostasis of non-alcoholic fatty liver disease: Molecular mechanism and promising therapeutic targets
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42. Surface-layer protein produced by Lactobacillus crispatus JCM 2009 ameliorates lipopolysaccharide-induced inflammation through autophagy cross-talk with the NF-κB signaling pathway
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43. Intercellular and inter-organ crosstalk in browning of white adipose tissue: molecular mechanism and therapeutic complications
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44. Proteostasis in thermogenesis and obesity
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45. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue
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46. A phytoestrogen secoisolariciresinol diglucoside induces browning of white adipose tissue and activates non-shivering thermogenesis through AMPK pathway
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47. Genetically prolonged beige fat in male mice confers long-lasting metabolic health
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48. miR-188 promotes liver steatosis and insulin resistance via the autophagy pathway
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49. Olaparib induces browning of in vitro cultures of human primary white adipocytes
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50. Revisiting adipose thermogenesis for delaying aging and age-related diseases: Opportunities and challenges
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51. Liensinine Inhibits Beige Adipocytes Recovering to white Adipocytes through Blocking Mitophagy Flux In Vitro and In Vivo
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52. PPARα/γ synergism activates UCP1-dependent and -independent thermogenesis and improves mitochondrial dynamics in the beige adipocytes of high-fat fed mice
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53. Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy
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54. Control of Adipose Cell Browning and Its Therapeutic Potential
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55. Regulation of Adipose Thermogenesis and its Critical Role in Glucose and Lipid Metabolism
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56. Adipose tissue autophagy and homeostasis in alcohol-induced liver injury
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57. Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases
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58. Brown adipocytes from induced pluripotent stem cells—how far have we come?
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59. Essential role of systemic iron mobilization and redistribution for adaptive thermogenesis through HIF2-α/hepcidin axis
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60. Brown and Beige Adipose Tissues in Health and Disease
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61. Coexisting renal artery stenosis and metabolic syndrome magnifies mitochondrial damage, aggravating poststenotic kidney injury in pigs
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62. Mitoptosis, Twenty Years After
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63. NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
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64. Mitochondria-associated regulation in adipose tissues and potential reagents for obesity intervention
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65. Adipose tissue browning and thermogenesis under physiologically energetic challenges: a remodelled thermogenic system
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66. Regulators of mitochondrial quality control differ in subcutaneous fat of metabolically healthy and unhealthy obese monkeys
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67. Development, activation, and therapeutic potential of thermogenic adipocytes
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68. Effects of 1,25(OH)2D3 on lipid droplet growth in adipocytes
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71. β -Cypermethrin promotes the adipogenesis of 3T3-L1 cells via inducing autophagy and shaping an adipogenesis-friendly microenvironment
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72. Spermidine activates adipose tissue thermogenesis through autophagy and fibroblast growth factor 21
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73. Chronic arsenic exposure impairs adaptive thermogenesis in male C57BL/6J mice
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74. Erythropoietin reduces fat mass in female mice lacking estrogen receptor alpha
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75. Novel Genetic Locus of Visceral Fat and Systemic Inflammation
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76. Thermogenic Activation Downregulates High Mitophagy Rate in Human Masked and Mature Beige Adipocytes
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77. Adipogenesis in Different Body Depots and Tumor Development
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79. Loss of lymphocyte cytosolic protein 1 (LCP1) induces browning in 3T3-L1 adipocytes via β3-AR and the ERK-independent signaling pathway
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80. Miquelianin, a main functional flavonoid of lotus leaf, induces thermogenic signature via p38‐PINK1‐PARKIN‐mediated mitophagy and mimicking NRF2 signaling during brown adipocyte differentiation
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81. Brown fat thermogenesis: Stability of developmental programming and transient effects of temperature and gut microbiota in adults
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82. The macroenviromental control of cancer metabolism by p62
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83. Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation
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93. Degradative and Non-Degradative Roles of Autophagy Proteins in Metabolism and Metabolic Diseases
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98. Brown adipocyte and browning thermogenesis: metabolic crosstalk beyond mitochondrial limits and physiological impacts
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100. Turnover and replication analysis by isotope labeling (TRAIL) reveals the influence of tissue context on protein and organelle lifetimes
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