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Lactate Attenuates Synaptic Transmission and Affects Brain Rhythms Featuring High Energy Expenditure

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Lactate as a determinant of neuronal excitability, neuroenergetics and beyond

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Rheb mediates neuronal-activity-induced mitochondrial energetics through mTORC1-independent PDH activation

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Metabolic Recruitment in Brain Tissue

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Mini-review: Brain energy metabolism and its role in animal models of depression, bipolar disorder, schizophrenia and autism

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The Astrocyte: Metabolic Hub of the BrainPreprint

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Enlightening brain energy metabolism

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Breakdown and repair of metabolism in the aging brain

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Transfer of Damaged Mitochondria from Cancer Cells to Cancer-Associated Fibroblasts Promotes Tyrosine Kinase Inhibitor Tolerance in EGFR -Mutant Lung Cancer

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A Dual Nanosensor Approach to Determine the Cytosolic Concentration of ATP in Astrocytes

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Control of cardiac contraction by sodium: Promises, reckonings, and new beginnings

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Inhibition of ATP-sensitive potassium channels exacerbates anoxic coma inLocusta migratoria

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qMaLioffG: a genetically encoded green fluorescence lifetime-based indicator enabling quantitative imaging of intracellular ATP

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Search for Intracellular Sensors Involved in the Functioning of Monovalent Cations as Secondary Messengers

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Ion gradient-driven bifurcations of a multi-scale neuronal model

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Detection of Osmotic Shock-Induced Extracellular Nucleotide Release with a Genetically Encoded Fluorescent Sensor of ADP and ATP

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Dynamics of Neuronal and Astrocytic Energy Molecules in Epilepsy

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Neuronal MCT2 promotes angiogenesis via lactate in the developing mouse neocortex

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ATP Metabolism of Astrocytes: Consumption, Regeneration and Restoration

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Extracellular lactate as an alternative energy source for retinal bipolar cells

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Pyruvate dehydrogenase complex E1 subunit α crotonylation modulates cocaine-associated memory through hippocampal neuron activation

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Measuring enzyme activities in crude homogenates: Na+/K+-ATPase as a case study in optimizing assays

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Lighting up Pyruvate Metabolism in Saccharomyces cerevisiae by a Genetically Encoded Fluorescent Biosensor

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Lactate Transport via Glial MCT1 and Neuronal MCT2 Is Not Required for Synchronized Synaptic Transmission in Hippocampal Slices Supplied With Glucose

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Various Dynamics of Amplitude Regulation Within a Class of 3D Rulkov Neurons

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Scale-spanning crosstalk between metabolism and information processing

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A Standardized Brain Molecular Atlas: A Resource for Systems Modeling and Simulation

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Actin cytoskeletal dynamics do not impose an energy drain on growth cone bioenergetics

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MCT4 is a high affinity transporter capable of exporting lactate in high-lactate environmentsPreprint

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Activation of the pentose phosphate pathway flux by hydrogen peroxide is not regulated by NADPH‐mediated feedback inhibition

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Activity-dependent protein synthesis in neurons requires microglial-metabolic coupling

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A power-adaptive neuron model and circuit implementation

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Monocarboxylate Transport in Drosophila Larval Brain during Low and High Neuronal ActivityPreprint

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Energetic diversity in retinal ganglion cells is modulated by neuronal activity and correlates with resilience to degeneration

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Ketosis regulates K+ ion channels, strengthening brain-wide signaling disrupted by age

van Nieuwenhuizen, H., Chesebro, A. G., Polizu, C., Clarke, K., Strey, H. H., Weistuch, C., & Mujica-Parodi, L. R. (2024) · Imaging Neuroscience · doi:10.1162/imag_a_00163 · Cited by 6

Functional Organization of Glycolytic Metabolon on MitochondriaPreprint

Wang, H., Vant, J., Wu, Y., Sánchez, R. G., Micou, M. L., Zhang, A. J., Luczak, V., Yu, S. B., Jabbo, M., Yoon, S., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.26.554955 · Cited by 5

Presynaptic ATP Decreases During Physiological‐Like Activity in Neurons Tuned for High‐Frequency Transmission

Straub, I., Kunstmann, L., Baeza‐Lehnert, F., Chowdhry, S., Renden, R., Gonzalez‐Aragón, G., Groschup, B., Hofmann, T. F., Jovanović, S., Sonntag, M., et al. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.70212 · Cited by 5

Differences in cytosolic glucose dynamics in astrocytes and adipocytes measured by FRET-based nanosensors

Chowdhury, H. H. (2020) · Biophysical Chemistry · doi:10.1016/j.bpc.2020.106377 · Cited by 4

Unveiling the role of local metabolic constraints on the structure and activity of spiking neural networks

Jaras, I., Orchard, M. E., Maldonado, P., & Vergara, R. C. (2025) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1013148 · Cited by 3

Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activationPreprint

Todorova, V., Stauffacher, M. F., Ravotto, L., Nötzli, S., Karademir, D., Ebner, L. J. A., Imsand, C., Hauck, S. M., Samardzija, M., Saab, A. S., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-2080894/v1 · Cited by 4

GLUT1 ablation in astrocytes paradoxically improves central and peripheral glucose metabolism via enhanced insulin-stimulated ATP releasePreprint

Ardanaz, C. G., de la Cruz, A., Elizalde-Horcada, M., Puerta, E., Ramírez, M. J., Ortega, J. E., Urbiola, A., Ederra, C., Ariz, M., Ortíz-de-Solórzano, C., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.06.511112 · Cited by 4

A dual emission ratiometric nanothermometer for evaluating cell temperature during energy metabolism

Yin, N., Wang, X., Shu, Y., & Wang, J. (2025) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2025.126163 · Cited by 3

Hyperglycaemic Metabolic Complications of Ischemic Brain: Current Therapeutics, Anti-Diabetics and Stem Cell Therapy

Chavda, V. K., & Patel, S. (2022) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527321666220609200852 · Cited by 3

Impairment of the blood-brain barrier accelerates a negative ultraslow potential in the locust CNS

Robertson, R. M., Donini, A., & Wang, Y. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00191.2025 · Cited by 2

Sex-specific resilience of neocortex to food restriction

Padamsey, Z., Katsanevaki, D., Maeso, P. A., Rizzi, M., Osterweil, E. K., & Rochefort, N. L. (2024) · eLife · doi:10.7554/elife.93052.3 · Cited by 2

Challenges and Frontiers in Computational Metabolic Psychiatry

Chesebro, A. G., Antal, B. B., Weistuch, C., & Mujica-Parodi, L. R. (2024) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2024.10.011 · Cited by 2

Variable bioenergetic sensitivity of neurons and astrocytes to insulin and extracellular glucose

Sims, S. L., Frazier, H. N., Case, S. L., Lin, R., Trosper, J. N., Vekaria, H. J., Sullivan, P. G., & Thibault, O. (2024) · npj Metabolic Health and Disease · doi:10.1038/s44324-024-00037-y · Cited by 2

Seizure and redox rescue in a model of glucose transport deficiency

Coggan, J. S., Shichkova, P., Markram, H., & Keller, D. X. (2025) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1012959 · Cited by 2

Perfect energy stability in neurons

Barros, L. F., & Baeza‐Lehnert, F. (2019) · Aging · doi:10.18632/aging.102257 · Cited by 2

Energy paradox in REM sleep: balancing supply and consumption in brain metabolism

Takahashi, Y., Ikoma, Y., & Matsui, K. (2026) · Communications Biology · doi:10.1038/s42003-026-10646-6 · Cited by 1

Actin(g) toward a revised understanding of the role of cytoskeletal dynamics in neuronal bioenergetics

Holland, S. M., & Gallo, G. (2024) · Neural Regeneration Research · doi:10.4103/1673-5374.392863 · Cited by 1

Contribution of Monovalent (Na+ and K+) and Divalent (Ca2+) Ions to the Mechanisms of Synaptic Plasticity

Smolyaninova, L. V., Shiyan, A. A., Maksimov, G. V., & Orlov, S. N. (2021) · Biochemistry (Moscow) Supplement Series A Membrane and Cell Biology · doi:10.1134/s1990747820050062 · Cited by 1

Lactate’s behavioral switch in the brain: An in-silico model

Soltanzadeh, M., Blanchard, S., Soucy, J., & Benali, H. (2023) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2023.111648 · Cited by 1

Visualizing Monocarboxylates and Other Relevant Metabolites in the Ex Vivo Drosophila Larval Brain Using Genetically Encoded Sensors

González‐Gutiérrez, A., Gaete, J., Esparza, A., Toledo, J. A., Köhler-Solís, A., & Sierralta, J. A. (2023) · Journal of Visualized Experiments · doi:10.3791/65846 · Cited by 1

Sex-specific resilience of neocortex to food restriction

Padamsey, Z., Katsanevaki, D., Maeso, P. A., Rizzi, M., Osterweil, E. K., & Rochefort, N. L. (2023) · eLife · doi:10.7554/elife.93052 · Cited by 2

An expanded palette of ATP sensors for subcellular and multiplexed imagingPreprint

Sahan, A. Z., Youngblood, E., Das, S., Schmitt, D. L., & Zhang, J. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.01.538722 · Cited by 1

A challenge to biochemists

Hill, A. V. (1950) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(50)90003-5 · Cited by 70

Non-preferential fuelling of the Na+/K+-ATPase pump

Fernández‐Moncada, I., & Barros, L. F. (2014) · Biochemical Journal · doi:10.1042/bj20140003 · Cited by 42

Non-canonical control of neuronal energy status by th Na+ pump

Baeza-Lehnert, F., Saab, A. S., Gutierrez, R., Larenas, V., Diaz, E., Horn, M., Vargas, M., Hosli, L., Stobart, J. L., Hirrlinger, J., et al. (2019) · MPG.PuRe (Max Planck Society)

The Na(+)/K(+) pump dominates control of glycolysis in hippocampal dentate granule cells

Meyer, D. J., Díaz-García, C. M., Nathwani, N., Rahman, M., & Yellen, G. (2022) · eLife · doi:10.7554/elife.81645 · Cited by 40

Relationships between the neuronal sodium/potassium pump and energy metabolism. Effects of K+, Na+, and adenosine triphosphate in isolated brain synaptosomes.

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