The DOI matches its Crossref record; 44 of the 46 references it cites were found in a registry or an index.
Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with Metabolic Syndrome
Open accessAbstract
In animal models, time-restricted feeding (TRF) can prevent and reverse aspects of metabolic diseases. Time-restricted eating (TRE) in human pilot studies reduces the risks of metabolic diseases in otherwise healthy individuals. However, patients with diagnosed metabolic syndrome often undergo pharmacotherapy, and it has never been tested whether TRE can act synergistically with pharmacotherapy in animal models or humans. In a single-arm, paired-sample trial, 19 participants with metabolic syndrome and a baseline mean daily eating window of ≥14 h, the majority of whom were on a statin and/or antihypertensive therapy, underwent 10 h of TRE (all dietary intake within a consistent self-selected 10 h window) for 12 weeks. We found this TRE intervention improves cardiometabolic health for patients with metabolic syndrome receiving standard medical care including high rates of statin and anti-hypertensive use. TRE is a potentially powerful lifestyle intervention that can be added to standard medical practice to treat metabolic syndrome. VIDEO ABSTRACT.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Recent human trials on TRE have highlighted numerous beneficial metabolic effects of TRE, e.g., improved mean daily glucose levels (107, 108), fasting glucose levels (108–110), insulin resistance (108, 110, 111) or insulin sensitivity (112, 113), triglyceride levels (107, 109, 114, 115), total cholesterol (115, 116), and LDL cholesterol levels (116).”
From Meal timing and its role in obesity and associated diseases (2024) · cites this paper as [116]
The cited source says what the claim attributes to it.
In the citing paper
“The presence of MetS increases the risk of developing cardiovascular diseases (CVDs) twofold, and the risk of all-cause mortality by a factor of 1.5 [2, 3].”
From Machine learning with the body roundness index and associated indicators: a new approach to predicting metabolic syndrome (2025) · cites this paper as [3]
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“The presence of MetS increases the risk of developing cardiovascular diseases (CVDs) twofold, and the risk of all-cause mortality by a factor of 1.5 [2, 3].”
From Machine learning with the body roundness index and associated indicators: a new approach to predicting metabolic syndrome (2025) · cites this paper as [3]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
Yuan, X., Zhu, C., Wang, M., Mo, F., Du, W., & Ma, X. (2018) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-17-0221 · Cited by 83
RetractedThe Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90047-4 · Cited by 35,234
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
(2002) · New England Journal of Medicine · doi:10.1056/nejmoa012512 · Cited by 19,011
Alberti, K. G. M. M., Eckel, R. H., Grundy, S. M., Zimmet, P. Z., Cleeman, J. I., Donato, K. A., Fruchart, J.-C., James, W. P. T., Loria, C. M., & Smith, S. C. (2009) · Circulation · doi:10.1161/circulationaha.109.192644 · Cited by 14,860
Lloyd-Jones, D. M., Hong, Y., Labarthe, D., Mozaffarian, D., Appel, L. J., Van Horn, L., Greenlund, K., Daniels, S., Nichol, G., Tomaselli, G. F., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.192703 · Cited by 4,750
National Sleep Foundation’s updated sleep duration recommendations: final report
Hirshkowitz, M., Whiton, K., Albert, S. M., Alessi, C., Bruni, O., DonCarlos, L., Hazen, N., Herman, J., Adams Hillard, P. J., Katz, E. S., et al. (2015) · Sleep Health · doi:10.1016/j.sleh.2015.10.004 · Cited by 2,348
Triglycerides and Cardiovascular Disease: A Scientific Statement From the American Heart Association
Miller, M., Stone, N. J., Ballantyne, C., Bittner, V., Criqui, M. H., Ginsberg, H. N., Goldberg, A. C., Howard, W. J., Jacobson, M. S., Kris-Etherton, P. M., et al. (2011) · Circulation · doi:10.1161/cir.0b013e3182160726 · Cited by 1,871
Sutton, E. F., Beyl, R., Early, K. S., Cefalu, W. T., Ravussin, E., & Peterson, C. M. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.04.010 · Cited by 1,531
Circadian physiology of metabolism
Panda, S. (2016) · Science · doi:10.1126/science.aah4967 · Cited by 1,092
Self-citationErvin, R. B. (2009) · PubMed · Cited by 1,000
Cited by
Sorted by citations
Items 901–947 of 947
Clinical Protocol for the Dietary Approaches to Longevity and Health (DiAL Health) Pilot Trial
Redman, L. M., Peterson, C. M., Dutton, G. R., Drews, K. L., Broyles, S. T., Dubin, R. L., Rogers, L. Q., Champagne, C. M., Villareal, D. T., Hsia, D. S., et al. (2026) · Current Developments in Nutrition · doi:10.1016/j.cdnut.2026.109462
Xiao, Y., Wang, J., Cui, J., Yin, S., Yang, Y., Yunjin, B., & Wang, J. H. (2026) · The FASEB Journal · doi:10.1096/fj.202601263rr
Duan, D., Carnell, S., Pilla, S. J., Chung, S. T., Clark, J. M., & Maruthur, N. M. (2026) · Obesity · doi:10.1002/oby.70270
Bardiaa, Y., Hmida, M., Kacem, S., & El-Abed, K. (2026) · Science & Sports · doi:10.1016/j.scispo.2026.04.007
Intermittent fasting: Impact, mechanisms and cautions across medical and lifestyle domains
Gautam, K. A., Lal, P., Malik, T., Gupta, S., Gasmi, M., Saurav, S., Tiwary, K., Mohan, A., Mishra, R., Ali, S., et al. (2026) · European Journal of Clinical Nutrition · doi:10.1038/s41430-026-01768-5
Sun, G., Jia, X., Zhang, H., Yu, R., Rong, S., Liu, Y., Qi, Y., & Chen, S. (2026) · Nutrients · doi:10.3390/nu18152546
Kundu, S., Islam, R., Sarkar, S., Chatterjee, O., Debnath, S., & Saha, L. (2026) · Genetics and Molecular Research · doi:10.4238/gcs7v027
Evaluación de los efectos del ayuno intermitente en adultos con Diabetes Mellitus
Cruz, D. G. D., Zenil, I. J. M., Ariza‐Ortega, J. A., & Calderón‐Ramos, Z. G. (2026) · Revista Científica de Salud y Desarrollo Humano · doi:10.61368/r.s.d.h.v7i3.1091
Time-restricted eating promotes sustained fat loss in DrosophilaPreprint
Gatto, J. A., Chang, T. Y., Kanmogne, W. C., Pen, S., Bortey, L., Kwon, J. N., Mahal, L., Kim, H. S., Berhanu, L., Oduk, F., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.08.05.742897
Timing of food intake impacts cardiovascular and neuroendocrine physiology and risk of disease
Latimer, M. N., Rhoads, M. K., & Pollock, D. M. (2026) · Cardiovascular Research · doi:10.1093/cvr/cvag169
Kovyanova, T. I., Nerush, M. O., Карагодин, В. П., Borodko, D. D., Rozhkova, U. V., Antonov, S. A., & Utkina, A. S. (2026) · Biomedicines · doi:10.3390/biomedicines14081868
Beyond dietary restriction: Towards next-generation precision diets for healthy aging
Huang, J., Huang, D., & Wu, Z. (2026) · The Innovation Nutrition · doi:10.59717/j.xinn-nutri.2026.100034
Sex- and Ketogenesis-Dependent Effects of Intermittent Fasting on Diet-Induced Fatty Liver Disease
Aslani, T., Asif, S., Oh, Y., Lee, H., Stocker, C., Pan, J., Kwon, S.-K., Dababneh, S., Zhao, X., Taylor, L., et al. (2026) · Diabetes · doi:10.2337/db25-1070
Straszewska, A., Woźniak, A., Sobantka, P., Mokrzecki, S., Król, M., Aleksandrowicz, K., Grodzka, Z., Meszka, M., Bełc, E., Brzezińska, K., et al. (2026) · International Journal of Innovative Technologies in Social Science · doi:10.31435/ijitss.3(51).2026.6182
Circadian mechanisms in heart failure: Cell-specific regulation and chrono-medicine
Cheng, S., Zhou, R., Zhang, Z., & Li, M. (2026) · Cell Insight · doi:10.1016/j.cellin.2026.100363
Zhai, Y. M., Liu, X., Wang, Z., Wang, M., Tang, G., Liu, Y., & Liang, H. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1910444
Gut microbiota on sleep disorders throughout the lifespan
Zhang, Z., Li, Q., Wang, X., Wang, W., & Zhang, F. (2026) · Microbiological Research · doi:10.1016/j.micres.2026.128724
Self-citationLiu, D., Xiong, L., Yang, T., 莊泉輝, & Zhan, Y. (2026) · Research Square · doi:10.21203/rs.3.rs-10375649/v1
Chrono-Nutritional Disruption as a Potential Modifiable Factor in Bipolar Disorder
Mazza, M., & Marano, G. (2026) · Nutrients · doi:10.3390/nu18183011
Integrated workplace health promotion for office workers: Mechanisms and intervention strategies
Lu, L.-T. (2026) · International Journal of Medical Science and Research · doi:10.66856/ijmsr.2026.8.3.8033
Berman, C., Vidmar, A. P., Garcia, J. F., Reid, M. W., Gonzalez, F., Sanchez, A. T., Salcedo-Rodriguez, E., & Raymond, J. K. (2026) · Diabetes Obesity and Cardiometabolic CARE · doi:10.2337/doc25-0087
Manzoor, H. M. I., Sultan, M. T., Hameed, A., Noman, A. M., Khalid, M., Kazmi, M., Aiman, S., Ramadan, M. F., Zongo, E., Rahim, M. A., et al. (2026) · Food Science & Nutrition · doi:10.1002/fsn3.72264
Lu, L., Gu, Y., Yang, W., & Liang, Z. (2026) · International Journal of General Medicine · doi:10.2147/ijgm.s644622
朱兴顺, Zhang, F., Wei, Y., Zhao, Y., & Guo, J. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1924972
Effects of time-restricted eating in early-stage Huntington’s disease: a pilot study
Wells, R. G., Neilson, L. E., McHill, A. W., Gray, N. E., Quinn, J. F., & Hiller, A. (2026) · Nature Metabolism · doi:10.1038/s42255-026-01612-x
Associations Between Fasting Duration and Nutrition Quotient Scores in Korean Adults
Kim, K., Lee, M., & Kim, E. (2026) · Journal of Nutrition Education and Behavior · doi:10.1016/j.jneb.2026.08.002
Velingkaar, N., Astaf’ev, A. A., Prabahar, A., Maravillas, M. A., Trokhimenko, E., Rom, J.-M. B., Asi, G. J., Piontkivska, H., Jiang, P., & Kondratov, R. V. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.118022
Prządka, J., Witaszczyk, M., Sołtan, A., Wiktorzak, N., Lipska, J., Koźma, G., Kochan-Olszewska, D., Rudnicki, L., Pawlicki, J., Laskus, J., et al. (2026) · Quality in Sport · doi:10.12775/qs.2026.73.75015
Louie, J. C. Y. (2026) · Current Obesity Reports · doi:10.1007/s13679-026-00765-w
Chrono-nutrition and sleep health in shift workers: a systematic review
Jeon, B., Baek, J., & Lee, Y. (2026) · Sleep and Biological Rhythms · doi:10.1007/s41105-026-00685-1
Jeyakumar, Y., Retnakaran, R. R., Feig, D. S., Zinman, B., & Kramer, C. K. (2026) · Journal of the Endocrine Society · doi:10.1210/jendso/bvag216
Jejum intermitente e seus efeitos metabólicos benefícios, riscos e evidências científicas atuais
Júnior, J. F. L., Miranda, A. L. A., Oliveira, P. H. C., & Couto, E. M. (2026) · Revista de Divulgação Científica Sena Aires · doi:10.36239/revisa.v15.n3.p1a13
Cozma, D. C., Tudoran, C., & Văcărescu, C. (2026) · Current Issues in Molecular Biology · doi:10.3390/cimb48101008
Hajhamidiasl, L., Baş, M., Yılmaz, Ö., Ozer, S., Yılmaz, S., & Arslan, S. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1968504
Daily Patterns in the Timing of Medication and Supplement Intake
Tran, T., Varshney, S., van Rosmalen, L., Levy, J. L., Laing, K. L., Manoogian, E. N. C., Lam, M. T. Y., & Panda, S. (2026) · Nutrients · doi:10.3390/nu18193291
Self-citationShrirame, D., Tatode, A., Dabhade, D., Taksande, J., Taksande, B. G., Kakade, O., & Umekar, M. (2026) · Physiology & Behavior · doi:10.1016/j.physbeh.2026.115522
Liu, M., Luo, M., Huang, Y., Ji, T., Wang, Y., Wang, Q., Huang, J., Jiang, T., Zhang, C., Mi, T., et al. (2026) · Aging Cell · doi:10.1111/acel.70728
Crononutrição: regulação do peso e a saúde metabólica
do Nascimento, O. V., Cavalcante, V., & Ferreira, I. D. J. (2026) · Revista Saúde dos Vales · doi:10.66104/ws4tjg58
Rejeki, P. S., & Purnomo, S. E. C. (2026) · Airlangga University Press eBooks · doi:10.20473/aup.1710
Siedentopp, U. (2026) · Chinesische Medizin / Chinese Medicine · doi:10.1007/s00052-026-00202-0
Lina, P. A. N. G., Li, S., Li, X., Mao, X., Gong, M., Ye, X., Yu, B., & Gou, C. (2026) · Nutrition Reviews · doi:10.1093/nutrit/nuag155
Empfehlungen zur Ernährung von Personen mit Typ-1-Diabetes mellitus – Praxisempfehlung der DDG
Rubin, D. F., Bosy‐Westphal, A., Kabisch, S., Kronsbein, P., Müssig, K., Simon, M., Tombek, A., Weber, K. S., & Skurk, T. (2026) · Diabetologie und Stoffwechsel · doi:10.1055/a-2874-4204
Precision nutrition and metabolic health: Integrating multi-omics for individualized prevention
Gu, W., Ning, H., Tian, Z., & Sun, C. (2026) · Metabolism and Diseases · doi:10.1016/j.metdis.2026.100040
Egorova, E. S., & Ahmetov, I. I. (2026) · Advances in Gerontology · doi:10.1134/s2079057026600424
Song, S., Lan, T., Park, S., Lee, J. E., & Park, Y. (2026) · Journal of Nutrition · doi:10.1016/j.tjnut.2026.101921
Metadata
- Authors
- Wilkinson, M. J., Manoogian, E. N. C., Zadourian, A., Lo, H., Fakhouri, S., Shoghi, A., Wang, X., Fleischer, J. G., Navlakha, S., Panda, S., & Taub, P. R.
- Affiliations
- University of California San Diego (US)
- Salk Institute for Biological Studies (US)
- Corresponding author
- Panda, Satchidananda
- Taub, Pam R.
- ORCID
- Venue
- Cell Metabolism
- Publisher
- Elsevier BV
- Published
- 2020-01
- Volume
- 31
- Issue
- 1
- Pages
- 92-104.e5
- ISSN
- 1550-4131 (ISSN-L)
- PMC
- PMC6953486
- OpenAlex
- W2992787906
- Cited by
- 927
- References
- 46
- Citations by year
- 2026: 121 · 2025: 150 · 2024: 143 · 2023: 124 · 2022: 158 · 2021: 125 · 2020: 102
- FWCI
- 66.37
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory) (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- American Ceramic Circle
- Amgen
- National Institutes of Health (DK115214, DK118278)
- Novo Nordisk
- Merck
- U.S. Department of Defense (W81XWH1810645)
- American College of Cardiology Foundation
- U.S. Department of Homeland Security (EMW-2016-FP-00788)
- Leona M. and Harry B. Helmsley Charitable Trust (2012-PG-MED002)
- University of California, San Diego
- Larry L. Hillblom Foundation
- Robert Wood Johnson Foundation
- Topics
- Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
- Keywords
- time-restricted eating, metabolic syndrome, weight loss, blood pressure, atherogenic lipids, statin therapy, antihypertensive therapy, cardiometabolic health, lifestyle intervention
- MeSH terms
- Antihypertensive Agents, Blood Cell Count, Blood Glucose, Blood Pressure, Body Weight, Circadian Rhythm, Diabetes Mellitus, Type 2, Fasting, Female, Follow-Up Studies, Humans, Lipids, Male, Middle Aged, Obesity, Sleep, Exercise, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Metabolic Syndrome, Lipid Metabolism
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
