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Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning
Open accessAbstract
The increased prevalence of obesity, diabetes, and cardiovascular risk factors in people hospitalized with severe COVID-19 illness has engendered considerable interest in the metabolic aspects of SARS-CoV-2-induced pathophysiology. Here, I update concepts informing how metabolic disorders and their co-morbidities modify the susceptibility to, natural history, and potential treatment of SARS-CoV-2 infection, with a focus on human biology. New data informing genetic predisposition, epidemiology, immune responses, disease severity, and therapy of COVID-19 in people with obesity and diabetes are highlighted. The emerging relationships of metabolic disorders to viral-induced immune responses and viral persistence, and the putative importance of adipose and islet ACE2 expression, glycemic control, cholesterol metabolism, and glucose- and lipid-lowering drugs is reviewed, with attention to controversies and unresolved questions. Rapid progress in these areas informs our growing understanding of SARS-CoV-2 infection in people with diabetes and obesity, while refining the therapeutic strategies and research priorities in this vulnerable population.
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“Increased inflammation, defective adaptative immune responses, endothelial dysfunction and coagulation-related disorders are all phenomena that have been well described in obesity and might represent a plausible explanation to the link we observed between high BMI and long COVID [33].”
From Female gender is associated with long COVID syndrome: a prospective cohort study (2022) · cites this paper as [33]
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RETRACTED: 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study
Huang, C., Huang, L., Wang, Y., Li, X., Ren, L., Gu, X., Kang, L., Guo, L., Liu, M., Zhou, X., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(20)32656-8 · Cited by 4,084
RetractedSafety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Polack, F. P., Thomas, S. J., Kitchin, N., Absalon, J., Gurtman, A., Lockhart, S., Perez, J. L., Pérez Marc, G., Moreira, E. D., Zerbini, C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2034577 · Cited by 14,592
Dexamethasone in Hospitalized Patients with Covid-19
The RECOVERY Collaborative Group (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2021436 · Cited by 11,477
Richardson, S., Hirsch, J. S., Narasimhan, M., Crawford, J. M., McGinn, T., Davidson, K. W., and the Northwell COVID-19 Research Consortium, Barnaby, D. P., Becker, L. B., Chelico, J. D., et al. (2020) · JAMA · doi:10.1001/jama.2020.6775 · Cited by 9,254
Remdesivir for the Treatment of Covid-19 — Final Report
Beigel, J. H., Tomashek, K. M., Dodd, L. E., Mehta, A. K., Zingman, B. S., Kalil, A. C., Hohmann, E., Chu, H. Y., Luetkemeyer, A., Kline, S., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2007764 · Cited by 7,267
Factors associated with COVID-19-related death using OpenSAFELY
Williamson, E. J., Walker, A. J., Bhaskaran, K., Bacon, S., Bates, C., Morton, C. E., Curtis, H. J., Mehrkar, A., Evans, D., Inglesby, P., et al. (2020) · Nature · doi:10.1038/s41586-020-2521-4 · Cited by 6,674
Voysey, M., Clemens, S. A. C., Madhi, S. A., Weckx, L. Y., Folegatti, P. M., Aley, P. K., Angus, B., Baillie, V. L., Barnabas, S. L., Bhorat, Q. E., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(20)32661-1 · Cited by 4,616
Docherty, A. B., Harrison, E. M., Green, C. A., Hardwick, H. E., Pius, R., Norman, L., Holden, K. A., Read, J. M., Dondelinger, F., Carson, G., et al. (2020) · BMJ · doi:10.1136/bmj.m1985 · Cited by 3,481
Attributes and predictors of long COVID
Sudre, C. H., Murray, B., Varsavsky, T., Graham, M. S., Penfold, R. S., Bowyer, R. C., Pujol, J. C., Klaser, K., Antonelli, M., Canas, L. S., et al. (2021) · Nature Medicine · doi:10.1038/s41591-021-01292-y · Cited by 2,707
Cummings, M. J., Baldwin, M. R., Abrams, D. C., Jacobson, S. D., Meyer, B. J., Balough, E. M., Aaron, J. G., Claassen, J., Rabbani, L. E., Hastie, J. M., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31189-2 · Cited by 2,245
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27 of the 190 references couldn’t be matched to a known paper.
Research works printed but not linked: 6
- Duarte-Salles, 2020, Baseline characteristics, management, and outcomes of 55,270 children and adolescents diagnosed with COVID-19 and 1,952,693 with influenza in France, Germany, Spain, South Korea and the United States: an international network cohort study, medRxiv
- Hall, 2020, ISARIC clinical data report 20 November 2020, medRxiv
- Israel, 2020, Large population study identifies drugs associated with reduced COVID-19 severity, medRxiv
- Petersen, 2020, Lack of antibodies to SARS-CoV-2 in a large cohort of previously infected persons, Clin. Infect. Dis.
- Savarraj, 2020, Three-month outcomes in hospitalized COVID-19 patients, medRxiv
- Woolcott, 2020, Diabetes and mortality among 1.6 million adult patients screened for SARS-CoV-2 in Mexico, medRxiv
Cited by
Sorted by citations
Items 101–200 of 269
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Zhao, X., Jiang, L., Sun, W., Tang, S., Kang, X., Gao, Q., Li, Z., An, X., & Lian, F. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1599969 · Cited by 15
Mendes, T. B., de Souza, A. B. C., & Halpern, B. (2022) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-022-00808-x · Cited by 12
Long-Term Persistence of COVID-Induced Hyperglycemia: A Cohort Study
Goel, V., Raizada, A., Aggarwal, A., Madhu, S., Kar, R., Agrawal, A., Mahla, V., & Goel, A. (2024) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.22-0695 · Cited by 11
Coronavirus Disease 2019, Diabetes, and Inflammation: A Systemic Review
Ferguson, M. R., Vel, J., Phan, V., Ali, R., Mabe, L., Cherner, A., Doan, T., Manakatt, B. M., Jose, M. M., Powell, A. R., et al. (2023) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2022.0090 · Cited by 10
Szczepanska‐Sadowska, E. K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25021310 · Cited by 10
A lipidomic view of SARS-CoV-2
Ebrahimi, K. H., & McCullagh, J. (2021) · Bioscience Reports · doi:10.1042/bsr20210953 · Cited by 12
Feng, S., Ali, M. S., Evdokimova, M., Reid, G., Clark, N. M., Uprichard, S. L., & Baker, S. C. (2022) · Viruses · doi:10.3390/v14071408 · Cited by 9
Guiot, J., Maes, N., Winandy, M., Henket, M. A., Ernst, B., Thys, M., Frix, A.-N., Morimont, P., Rousseau, A., Canivet, P., et al. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.930055 · Cited by 10
Avendaño, M. S., Perdices-López, C., Guerrero‐Ruiz, Y., Ruíz-Pino, F., Rodriguez-Sanchez, A. B., Sanchez-Tapia, M. J., Sobrino, V., Pineda, R., Barroso, A., Correa-Sáez, A., et al. (2024) · Metabolism · doi:10.1016/j.metabol.2024.155932 · Cited by 12
Pre-Existing Diabetes and COVID-Associated Hyperglycaemia in Patients with COVID-19 Pneumonia
Laurenzi, A., Caretto, A., Molinari, C., Bazzigaluppi, E., Brigatti, C., Marzinotto, I., Mercalli, A., Melzi, R., Nano, R., Tresoldi, C., et al. (2021) · Biology · doi:10.3390/biology10080754 · Cited by 10
Zeng, J., Liu, X., Wang, S., Yang, S., Jia, W., Han, K., Wang, C., Liu, M., Chen, Y., & He, Y. (2021) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2021.07.030 · Cited by 10
Sheet Barrier and Intubating Stylet
Tsai, P. B., & Luk, H. (2021) · Encyclopedia · doi:10.3390/encyclopedia1040081 · Cited by 10
Ferreira, J. E. D. S. M., Jansen, R. C., de Oliveira, L. R., Damasceno, D. F. O., de Oliveira, F. B. B., da Silva, M. J. N., Pereira, A. E. E., Ferreira, G. D. O., Silva, L. D. A., Costa, H. P., et al. (2022) · Editora In Vivo eBooks · doi:10.47242/978-65-995500-7-2-8 · Cited by 8
Obesity‐Induced Metabolic Priming Exacerbates SARS ‐ CoV ‐2 Inflammation
Davanzo, G. G., Castelucci, B. G., de Souza, G. F., Muraro, S. P., dos Reis, L. M., de Oliveira, I. B., Fachi, J. L., Virgílio-da-Silva, J. V., Berçot, M. R., Fernandes, M. F., et al. (2025) · Immunology · doi:10.1111/imm.13934 · Cited by 10
Zhang, P., Liu, Y., Li, C., Stine, L., Wang, P., Turnbull, M. W., Wu, H., & Liu, Q. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1110271 · Cited by 9
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zhang, G., Su, L., Wu, W., Qiao, Q., Gao, S., Zhang, Y., & Zhang, Y. (2024) · Virology Journal · doi:10.1186/s12985-024-02345-7 · Cited by 9
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McDonnell, M. E., Garg, R., Gopalakrishnan, G., Mitri, J., Weinstock, R. S., Greenfield, M., Katta, S. R., Lebastchi, J., Palermo, N. E., Radhakrishnan, R., et al. (2022) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgac587 · Cited by 9
Huang, L., Liang, M., & He, Y. (2023) · Journal of Korean Medical Science · doi:10.3346/jkms.2023.38.e209 · Cited by 9
Shin, C. H., Kim, K., Jeeva, S., & Kang, S. (2021) · Cells · doi:10.3390/cells10061412 · Cited by 9
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Landecker, H. L. (2024) · KZfSS Kölner Zeitschrift für Soziologie und Sozialpsychologie · doi:10.1007/s11577-024-00951-5 · Cited by 9
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Yang, J., Qu, Y., Yuan, Z., Lun, Y., Kuang, J., Shao, T., Qi, Y., Li, Y., & Zhu, L. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms27010147 · Cited by 8
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Lin, L., Chen, Z., Ding, T., Liu, H., Zhou, F., Huang, X., Zhang, X., Liu, W., Zhang, B., Yuan, Y., et al. (2021) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s332819 · Cited by 8
Israel, A., Schäffer, A. A., Merzon, E., Green, I., Magen, E., Golan‐Cohen, A., Vinker, S., & Ruppin, E. (2022) · Microorganisms · doi:10.3390/microorganisms10061238 · Cited by 9
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Liu, X., Du, Z., Wang, J., Wang, Q., Zheng, Y., Niu, L., Hao, C., Xue, D., & Zhang, Y. (2023) · Journal of Medical Virology · doi:10.1002/jmv.28455 · Cited by 8
Contiero, P., Borgini, A., Bertoldi, M., Abita, A. M., Cuffari, G., Tomao, P., D’Ovidio, M. C., Reale, S., Scibetta, S., Tagliabue, G., et al. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19084637 · Cited by 7
Silva, B. R. O., Rodrigues, W. F., Abadia, D. G. P., da Silva, D. A. A., Andrade-Silva, L. E., Desidério, C. S., Farnesi-de-Assunção, T. S., Costa-Madeira, J. C., Barbosa, R. M., Borges, A. V. B. E., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.899702 · Cited by 7
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Bonfrate, L., Ciaula, A. D., Khalil, M., Farella, I., Chirico, R., Vilahur, G., & Portincasa, P. (2023) · Internal and Emergency Medicine · doi:10.1007/s11739-022-03173-9 · Cited by 7
Trieger, G. W., Pessentheiner, A. R., Purcell, S. C., Green, C. R., DeForest, N., Willert, K., Majithia, A. R., Metallo, C. M., Godula, K., & Gordts, P. L. S. M. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.104611 · Cited by 7
Jiang, N., Yin, J., Lawrence, N., Meng, J., Maeyens, L. T., Xu, Z., Li, X., Ekane, M., Chaudhary, A., Cao, P., et al. (2025) · Aging Cell · doi:10.1111/acel.70210 · Cited by 7
Blood pH Analysis in Combination with Molecular Medical Tools in Relation to COVID-19 Symptoms
Siebert, H., Eckert, T., Bhunia, A., Klatte, N., Mohri, M., Siebert, S., Kozarova, A., Hudson, J. W., Zhang, R., Zhang, N., et al. (2023) · Biomedicines · doi:10.3390/biomedicines11051421 · Cited by 8
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Díaz-Casado, M. E., González‐García, P., López-Herrador, S., Hidalgo‐Gutiérrez, A., Jiménez-Sánchez, L., Barriocanal‐Casado, E., Bakkali, M., van de Lest, C. H. A., Corral-Sarasa, J., Zaal, E. A., et al. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2024.167283 · Cited by 6
Gulisija, D., González-Reymúndez, A., Fenton, J. I., Campos, G. D. L., Bray, M. S., & Vazquez, A. I. (2025) · Obesity · doi:10.1002/oby.24291 · Cited by 5
Birts, C. N., & Wilton, D. C. (2021) · Medical Hypotheses · doi:10.1016/j.mehy.2021.110646 · Cited by 6
The Insights on Why Diabetes Prevalence May Increase Amid or Post COVID-19 Pandemic
Sibiya, N. H., Mzimela, N. C., Mbatha, B., Ngubane, P. S., & Khathi, A. (2022) · Current Diabetes Reviews · doi:10.2174/1573399818666220411122345 · Cited by 7
Fomin, G., Tabynov, K., Islamov, R., Turebekov, N. A., Yessimseit, D. T., & Yerubaev, T. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1223086 · Cited by 6
COVID-19, Obesity, and GRP78: Unraveling the Pathological Link
Shin, J., & Shimomura, I. (2023) · Journal of Obesity & Metabolic Syndrome · doi:10.7570/jomes23053 · Cited by 6
Duarte, T., Silva, M. D. M., Michelotti, P., Barbosa, N. V., Feltes, B. C., Dorn, M., da Rocha, J. B. T., & Corte, C. L. D. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2022.166551 · Cited by 6
Zickler, M., Stanelle‐Bertram, S., Ehret, S., Heinrich, F., Lange, P., Schaumburg, B., Kouassi, N. M., Beck, S., Jaeckstein, M. Y., Mann, O., et al. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3939147 · Cited by 6
Fortuna, D., Caselli, L., Berti, E., & Moro, M. L. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-073471 · Cited by 5
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Travis, B. J., Elste, J., Gao, F., Joo, B. Y., Cuevas‐Nunez, M., Kohlmeir, E. K., Tiwari, V., & Mitchell, J. C. (2022) · Oral Diseases · doi:10.1111/odi.14319 · Cited by 5
Minoura, A., Sugiyama, T., Koyama, T., Yoshioka, T., & Tabuchi, T. (2022) · Scientific Reports · doi:10.1038/s41598-022-20716-4 · Cited by 5
Recent advances in the development of multiplexed nanophotonic biosensors.
Mcotshana, Z. Z., Thwala, L. N., Tlomatsane, M., Steen, E. E. V., & Mthunzi-Kufa, P. T. (2024) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2024.104246 · Cited by 6
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Henein, M. Y., Bytyçi, I., Nicoll, R., Shenouda, R., Ayad, S. W., Vancheri, F., & Cameli, M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10132752 · Cited by 5
Elkazzaz, M., Haydara, T., Abo-Amer, Y. E.-E., Sahyon, H. A. E., Shamkh, I. M., Magd, M. F. A. E., Çen, O., & Ahmed, A. K. K. (2021) · Research Square · doi:10.21203/rs.3.rs-936697/v2 · Cited by 5
Lu, P., Zhang, J., Liu, W. D., & Gao, F. (2025) · Journal of Computational Science · doi:10.1016/j.jocs.2025.102629 · Cited by 4
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Krupka, S., Hoffmann, A., Jasaszwili, M., Dietrich, A., Guiu‐Jurado, E., Klöting, N., & Blüher, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25052908 · Cited by 4
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Kellett, S. K., & Masterson, J. C. (2024) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiae126 · Cited by 5
Clinical characteristics of COVID-19 patients with complications: implications for management
Lan, F., Zhu, C., Jin, R., Zhou, L., Hu, Y., Zhao, J., Xu, S., Xia, Y., & Li, W. (2021) · Therapeutic Advances in Chronic Disease · doi:10.1177/20406223211041924 · Cited by 4
He, R., Guan, C., Zhao, X., Yu, L., & Cui, Y. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1364442 · Cited by 5
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Sun, L., Yang, X., Cao, B., Su, X., Wang, J., & Xu, C. (2024) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2024.12482 · Cited by 4
Elkazzaz, M., Haydara, T., Abo-Amer, Y. E.-E., Sahyon, H. A. E., Shamkh, I. M., Magd, M. F. A. E., & Ahmed, A. K. K. (2021) · Research Square · doi:10.21203/rs.3.rs-936697/v1 · Cited by 4
Panja, A., Manna, S., Chatterjee, M., Ghosh, T., Bid, S., & Choudhury, S. M. (2025) · Current Microbiology · doi:10.1007/s00284-025-04369-w · Cited by 3
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Fang, H., & Wang, Q. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-07717-x · Cited by 3
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Yarahmadi, A., Shahrokhi, S. Z., Azarpira, N., & Mostafavi‐Pour, Z. (2021) · Clinical Diabetology · doi:10.5603/dk.a2021.0056 · Cited by 3
Cutruzzolà, A., Parise, M., Fiorentino, R., Romano, A., Molinaro, V., Gnasso, A., Molfetta, S. D., & Irace, C. (2022) · Nutrients · doi:10.3390/nu14163316 · Cited by 3
Brown, J. A., Hauser, A., Abela, I. A., Pasin, C., Epp, S., Mohloanyane, T., Nsakala, B. L., Trkola, A., Labhardt, N. D., Kouyos, R. D., et al. (2023) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiad197 · Cited by 3
Hoste, L., Prytula-Ebels, A., Dehoorne, J., Bruyne, R. D., Biervliet, S. V., Waele, K. D., Maes, E., Bordon, V., Vanlander, A. V., Claes, K., et al. (2023) · Frontiers in Pediatrics · doi:10.3389/fped.2023.1210181 · Cited by 3
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Reddy, K. R., Faridi, K. F., Aggarwal, M., Tirumalai, A. A., Singh, T. K., Tejtel, S. K. S., Williams, K. A., Sr., Litwin, S. E., Dastmalchi, L. N., White, B. A., et al. (2024) · American Journal of Lifestyle Medicine · doi:10.1177/15598276241269532 · Cited by 3
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Jiang, R.-D., Luo, Y.-Z., Lin, H.-F., Zheng, X.-S., Zeng, W., Liu, M., Deng, H.-H., Wang, Q., Lai, Y., Chen, Y., et al. (2025) · iScience · doi:10.1016/j.isci.2025.111837 · Cited by 3
Holly, J. M. P. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.877973 · Cited by 3
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Rao, G., Sang, X., Zhu, X., Zou, S., Zhang, Y., Cheng, W., Tian, Y., & Fu, X. (2025) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70581 · Cited by 2
Mehrotra‐Varma, J., Henry, S. S., Chernoff, D., Galenchik-Chan, A., Duong, K. S., Mehrotra-Varma, S., Wang, S. H., & Duong, T. Q. (2025) · Diagnostics · doi:10.3390/diagnostics15151846 · Cited by 2
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Haque, A., & Pant, A. B. (2025) · Viruses · doi:10.3390/v17091150 · Cited by 3
van Baal, L., Tan, S., Führer-Sakel, D., Reinold, J., Dittmer, U., & Fiedler, M. (2025) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-025-01699-1 · Cited by 2
Wang, X., Li, M., Chi, Z., Wang, M., Liu, J., Li, A., Song, B., & Tong, L. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1769545 · Cited by 4
Zhang, X., Zhang, F., & Li, W. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1794628 · Cited by 2
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Yu, E. A., Jackman, R. P., Glesby, M. J., & Narayan, K. V. (2023) · Advances in Nutrition · doi:10.1016/j.advnut.2023.06.003 · Cited by 2
Li, L., Li, L., Cai, X., & Pan, Z. (2024) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s454408 · Cited by 2
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Wang, J., Huang, Y.-W., & Tao, F. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e30750 · Cited by 2
Zhang, L., Li, Y., Hu, W., Gao, S., Tang, Y., Sun, L., Jiang, N., Xiao, Z., Han, L., & Zhou, W. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.155784 · Cited by 2
Aspirin reduces the risk of type 2 diabetes associated with COVID-19
Trimarco, V., Izzo, R., Pacella, D., Manzi, M. V., Jankauskas, S. S., Gallo, P., Rozza, F., Giugliano, G., Spinelli, A. M., Esposito, G., et al. (2025) · npj Metabolic Health and Disease · doi:10.1038/s44324-025-00072-3 · Cited by 2
Covid-19 and Diabetes Mellitus
ATTRI, B., GUPTA, Y., & TANDON, N. (2021) · The National Medical Journal of India · doi:10.25259/nmji_429_21 · Cited by 2
Sudin, S. А. (2023) · Health Risk Analysis · doi:10.21668/health.risk/2023.3.18 · Cited by 2
Bliss, J. W., Lavery, J. A., Underwood, W. P., Chun, S. S., Fickera, G. A., Lee, C. P., Corcoran, S., Maloy, M., Polubriaginof, F. C. G., Kelly, D. W., et al. (2022) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-21-1186 · Cited by 2
Guglielmi, V., Campanelli, M., Bianciardi, E., Benavoli, D., Colangeli, L., D’Adamo, M., Sbraccia, P., & Gentileschi, P. (2022) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-022-01438-y · Cited by 2
García-Ulloa, A. C., Tron-Gomez, M. S., Díaz-Pineda, M., Hernández-Juárez, D., Landa-Anell, M. V., Melgarejo-Hernández, M. A., & Hernández-Jiménez, S. C. (2022) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s379547 · Cited by 2
Reștea, P.-A., Muresan, M. E., Voicu, A., Jurca, T., Pallag, A., Marian, E., Vicaș, L. G., Jeican, I. I., & Crivii, C. B. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13030392 · Cited by 2
Infectious diseases: overview, challenges, and perspectives
Vázquez-Muñoz, R. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-99148-3.00010-8 · Cited by 3
Shams, E., Kamalumpundi, V., Cheng, L., Taiwo, A., Shibli-Rahhal, A. A., Dokun, A. O., & Correia, M. (2023) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20220277 · Cited by 2
Wasnik, R. N., Vincze, F., Földvári, A., Pálinkás, A., & Sándor, J. (2023) · Healthcare · doi:10.3390/healthcare11091220 · Cited by 2
Colleluori, G., Graciotti, L., Pesaresi, M., Vincenzo, A. D., Perugini, J., Mercurio, E. D., Caucci, S., Bagnarelli, P., Zingaretti, C. M., Nisoli, E., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.30.466586 · Cited by 2
Characterization of a SARS-CoV-2 infection model in golden hamsters with diabetes mellitus
Lin, H., Jiang, R.-D., Qin, R.-X., Yao, B., Zeng, W., Gao, Y., Shi, A.-M., Li, J., & Liu, M. (2025) · Virologica Sinica · doi:10.1016/j.virs.2025.05.001 · Cited by 1
The impact of common chronic diseases on the severity of clinical symptoms of COVID-19
Pietrzyk, B., Dolibog, P., Fajferek, T., Joniec, A., Mikołajczyk, J., Kaczara, S., & Kołodziej, E. (2025) · Annales Academiae Medicae Silesiensis · doi:10.18794/aams/205505 · Cited by 1
Rodrigues, C. M., Santos, J. D., Garcia, B. C. C., Ottoni, M. H. F., Costa, K. B., Costa, M. L. B., Figueiredo, V. G., Macedo, D., de Oliveira, D. B., Vieira, E. R., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1729494 · Cited by 1
Петрович, И. Г., Serebryakova, O. A., SYUZEV, K. N., Gainullina, A. K., & DOLGANOVA, D. A. (2022) · The Bulletin of Contemporary Clinical Medicine · doi:10.20969/vskm.2022.15(1).34-42 · Cited by 1
Baseline moderate-range albuminuria is associated with protection against severe COVID-19 pneumonia
Bashkin, A., Shehadeh, M., Shbita, L., Namoura, K., Haiek, R., Kuyantseva, E., Boulos, Y., Yakir, O., & Kruzel-Davila, E. (2022) · World Journal of Diabetes · doi:10.4239/wjd.v13.i12.1154 · Cited by 1
Fauste, E., Donis, C., Pérez-Armas, M., Rodríguez, L., Rodrigo, S., Álvarez‐Millán, J. J., Otero, P., Panadero, M. I., & Bocos, C. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105366 · Cited by 1
Animal models and SARS-CoV-2-induced pulmonary and neurological injuries
Pinto, M., da Silva, A. D. S., Rodrigues, D. D. R. F., Müller, R., de Vasconcelos, G. A. L. B. M., Neves, P. C. D. C., Oliveira, J. D. D., & Marchevsky, R. (2023) · Memórias do Instituto Oswaldo Cruz · doi:10.1590/0074-02760220239 · Cited by 1
Manaka, K., Kato, S., Sakamoto, R., Yamakage, H., Uema, T., Kawai, S., Shibata, M., Hiratsuka, I., Nakachi, S., Onoue, T., et al. (2024) · Endocrine Journal · doi:10.1507/endocrj.ej23-0671 · Cited by 1
Chikkahonnaiah, P., Dallavalasa, S., Tulimilli, S. V., Dubey, M., Byrappa, S. H., Amachawadi, R. G. G., Madhunapantula, S. V., & Veeranna, R. P. (2024) · Diseases · doi:10.3390/diseases12070143 · Cited by 1
Varghese, N. E., Chandrasekaran, V., Kandasamy, K., & Ramalingam, K. (2024) · Journal of Young Pharmacists · doi:10.5530/jyp.2024.16.59 · Cited by 1
Yu, L., Li, G.-H., Li, J., Luo, Z., Lin, Y., Lan, N., & Zhang, X. (2025) · PeerJ · doi:10.7717/peerj.18865 · Cited by 1
Sjöholm, Å., & Bandert, A. (2025) · JCEM Case Reports · doi:10.1210/jcemcr/luaf151 · Cited by 1
Response to: Glycemic control and COVID-19 outcomes: the missing metabolic players
Zhan, K., Zhang, X., Wang, B., Jiang, Z., Fang, X., Yang, S., Jia, H., Li, L., Cao, G., Zhang, K., et al. (2022) · QJM · doi:10.1093/qjmed/hcac044 · Cited by 1
Gaba, A., Nambi, N. K., & Joshi, A. (2022) · Global Journal of Health Science · doi:10.5539/gjhs.v14n7p1 · Cited by 1
Perceptions about the Management of Patients with DM2 and COVID-19 in the Hospital Care Setting
Gómez‐Huelgas, R., & Peralta, F. G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11154507 · Cited by 2
Zaccardi, F., Tan, P. S., Coupland, C. A. C., Shah, B. R., Clift, A. K., Saatci, D., Patone, M., Griffin, S. J., Dambha‐Miller, H., Khunti, K. K., et al. (2022) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14872 · Cited by 1
Metadata
- Authors
- Drucker, D. J.
- Affiliations
- University of Toronto (CA)
- Corresponding author
- Drucker, Daniel J.
- ORCID
- Drucker, Daniel J.
- Venue
- Cell Metabolism
- Publisher
- Elsevier BV
- Published
- 2021-03
- Volume
- 33
- Issue
- 3
- Pages
- 479-498
- ISSN
- 1550-4131 (ISSN-L)
- PMC
- PMC7825982
- OpenAlex
- W3124063857
- Cited by
- 272
- References
- 190
- Citations by year
- 2026: 16 · 2025: 25 · 2024: 38 · 2023: 49 · 2022: 86 · 2021: 58
- FWCI
- 6.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 366 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Cell Metabolism (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research (154321)
- University of Toronto
- Novo Nordisk
- Novo Nordisk Fonden
- Pfizer (GLP-2)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- SARS-CoV-2, COVID-19 pandemic, obesity, diabetes mellitus, metabolic disorders, ACE2 expression, adipose tissue, pancreatic islets, glycemic control, cholesterol metabolism, antidiabetic drugs, lipid-lowering drugs, immune response, viral persistence, disease severity, genetic susceptibility, comorbidities
- MeSH terms
- Heart Disease Risk Factors, Angiotensin-Converting Enzyme 2, COVID-19, SARS-CoV-2, COVID-19 Drug Treatment, Blood Glucose, Cholesterol, Diabetes Mellitus, Glucose, Humans, Hyperglycemia, Metabolic Diseases, Obesity, Comorbidity, Genetic Predisposition to Disease
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