Viral vectors as vaccine platforms: deployment in sight

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

Rerks‐Ngarm, S., Pitisuttithum, P., Nitayaphan, S., Kaewkungwal, J., Chiu, J., Paris, R., Premsri, N., Namwat, C., de Souza, M. S., Adams, E. M., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0908492 · Cited by 3,036 · see citing works

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

Buchbinder, S. P., Mehrotra, D. V., Duerr, A., Fitzgerald, D. W., Mogg, R., Li, D., Gilbert, P. B., Lama, J. R., Marmor, M., del Rio, C., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)61591-3 · Cited by 1,713 · see citing works

HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case–cohort analysis

McElrath, M. J., Rosa, S. C. D., Moodie, Z., Dubey, S. A., Kierstead, L. S., Janes, H., Defawe, O., Carter, D. K., Hural, J., Akondy, R. S., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)61592-5 · Cited by 712 · see citing works

Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys

Barouch, D. H., O’Brien, K. L., Simmons, N. L., King, S. L., Abbink, P., Maxfield, L. F., Sun, Y.-H., Porte, A. L., Riggs, A. M., Lynch, D. M., et al. (2010) · Nature Medicine · doi:10.1038/nm.2089 · Cited by 384 · see citing works

Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination

Wei, C., Boyington, J. C., McTamney, P. M., Kong, W., Pearce, M. B., Xu, L., Andersen, H., Rao, S. S., Tumpey, T. M., Yang, Z., et al. (2010) · Science · doi:10.1126/science.1192517 · Cited by 337 · see citing works

Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization

Gao, F., Morrison, S. G., Robertson, D. L., et al. (1996) · Journal of Virology · doi:10.1128/jvi.70.3.1651-1667.1996 · Cited by 286 · see citing works

Design and Pre-Clinical Evaluation of a Universal HIV-1 Vaccine

Létourneau, S., Im, E., Mashishi, T., Brereton, C., Bridgeman, A., Yang, H., Dorrell, L., Dong, T., Korber, B., McMichael, A. J., et al. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000984 · Cited by 280 · see citing works

New Insights on Adenovirus as Vaccine Vectors

Lasaro, M. O., & Ertl, H. C. J. (2009) · Molecular Therapy · doi:10.1038/mt.2009.130 · Cited by 263 · see citing works

Structural and Phylogenetic Analysis of Adenovirus Hexons by Use of High-Resolution X-Ray Crystallographic, Molecular Modeling, and Sequence-Based Methods

Rux, J. J., Kuser, P. R., & Burnett, R. M. (2003) · Journal of Virology · doi:10.1128/jvi.77.17.9553-9566.2003 · Cited by 238 · see citing works

Immunologic Basis of Vaccine Vectors

Liu, M. A. (2010) · Immunity · doi:10.1016/j.immuni.2010.10.004 · Cited by 237 · see citing works

Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys

Santra, S., Liao, H., Zhang, R., et al. (2010) · Nature Medicine · doi:10.1038/nm.2108 · Cited by 235 · see citing works

A Simian Replication-Defective Adenoviral Recombinant Vaccine to HIV-1 Gag

Fitzgerald, J. C., Gao, G., Reyes‐Sandoval, A., Pavlakis, G. N., Xiang, Z., Wlazlo, A. P., Giles‐Davis, W., Wilson, J. M., & Ertl, H. C. J. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.3.1416 · Cited by 216 · see citing works

Novel, Chimpanzee Serotype 68-Based Adenoviral Vaccine Carrier for Induction of Antibodies to a Transgene Product

Xiang, Z., Gao, G., Reyes‐Sandoval, A., Cohen, C. J., Li, Y., Bergelson, J. M., Wilson, J. M., & Ertl, H. C. J. (2002) · Journal of Virology · doi:10.1128/jvi.76.6.2667-2675.2002 · Cited by 194 · see citing works

Chimpanzee Adenovirus Antibodies in Humans, Sub-Saharan Africa

Xiang, Z., Li, Y., Cun, A., Yang, W. P., Ellenberg, S. S., Switzer, W. M., Kalish, M. L., & Ertl, H. C. J. (2006) · Emerging infectious diseases · doi:10.3201/eid1210.060078 · Cited by 178 · see citing works

Prime-Boost Immunization with Adenoviral and Modified Vaccinia Virus Ankara Vectors Enhances the Durability and Polyfunctionality of Protective Malaria CD8 + T-Cell Responses

Reyes‐Sandoval, A., Berthoud, T. K., Alder, N. C., Siani, L., Gilbert, S. C., Nicosia, A., Colloca, S., Cortese, R., & Hill, A. V. S. (2009) · Infection and Immunity · doi:10.1128/iai.00740-09 · Cited by 175 · see citing works

Long-Term Thermostabilization of Live Poxviral and Adenoviral Vaccine Vectors at Supraphysiological Temperatures in Carbohydrate Glass

Alcock, R. S., Cottingham, M. G., Rollier, C. S., Furze, J. M., Costa, S. D. D., Hanlon, M., Spencer, A. J., Honeycutt, J. D., Wyllie, D. H., Gilbert, S. C., et al. (2010) · Science Translational Medicine · doi:10.1126/scitranslmed.3000490 · Cited by 160 · see citing works

Priming Immunization with DNA Augments Immunogenicity of Recombinant Adenoviral Vectors for Both HIV-1 Specific Antibody and T-Cell Responses

Koup, R. A., Roederer, M., Lamoreaux, L., Fischer, J., Novik, L., Nason, M., Larkin, B. D., Enama, M. E., Ledgerwood, J. E., Bailer, R. T., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009015 · Cited by 133 · see citing works

IMVAMUNE ® : modified vaccinia Ankara strain as an attenuated smallpox vaccine

Kennedy, J. S., & Greenberg, R. N. (2008) · Expert Review of Vaccines · doi:10.1586/14760584.8.1.13 · Cited by 133 · see citing works

Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity

Flatz, L., Hegazy, A., Bergthaler, A., Verschoor, A., Claus, C., Fernandez, M., Gattinoni, L., Johnson, S. B., Kreppel, F., Kochanek, S., et al. (2010) · Nature Medicine · doi:10.1038/nm.2104 · Cited by 133 · see citing works

AIDS Clinical Trials Group 5197: A Placebo‐Controlled Trial of Immunization of HIV‐1–Infected Persons with a Replication‐Deficient Adenovirus Type 5 Vaccine Expressing the HIV‐1 Core Protein

Schooley, R. T., Spritzler, J., Wang, H., et al. (2010) · The Journal of Infectious Diseases · doi:10.1086/655468 · Cited by 118 · see citing works

Vaccine Delivery Methods Using Viral Vectors

Bråve, A., Ljungberg, K., Wahrén, B., & Liu, M. A. (2006) · Molecular Pharmaceutics · doi:10.1021/mp060098+ · Cited by 110 · see citing works

A Phase 1/2 Study of a Multiclade HIV‐1 DNA Plasmid Prime and Recombinant Adenovirus Serotype 5 Boost Vaccine in HIV‐Uninfected East Africans (RV 172)

Kibuuka, H. N., Kimutai, R., Maboko, L., et al. (2010) · The Journal of Infectious Diseases · doi:10.1086/650299 · Cited by 106 · see citing works

Recombination-Mediated Genetic Engineering of a Bacterial Artificial Chromosome Clone of Modified Vaccinia virus Ankara (MVA)

Cottingham, M. G., Andersen, R. F., Spencer, A. J., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001638 · Cited by 93 · see citing works

Human Immunodeficiency Virus Type 1-Specific Immune Responses in Primates upon Sequential Immunization with Adenoviral Vaccine Carriers of Human and Simian Serotypes

Reyes‐Sandoval, A., Fitzgerald, J. C., Grant, R., Roy, S., Xiang, Z., Li, Y., Gao, G., Wilson, J. M., & Ertl, H. C. J. (2004) · Journal of Virology · doi:10.1128/jvi.78.14.7392-7399.2004 · Cited by 91 · see citing works

Single‐dose immunogenicity and protective efficacy of simian adenoviral vectors against Plasmodium berghei

Reyes‐Sandoval, A., Sridhar, S., Berthoud, T. K., Moore, A., Harty, J. T., Gilbert, S. C., Gao, G., Ertl, H. C. J., Wilson, J. M., & Hill, A. V. S. (2008) · European Journal of Immunology · doi:10.1002/eji.200737672 · Cited by 90 · see citing works

Prevalence of serum neutralizing antibodies against chimpanzee adenovirus 63 and human adenovirus 5 in Kenyan Children, in the context of vaccine vector efficacy

Dudareva, M., Andrews, L., Gilbert, S. C., et al. (2009) · Vaccine · doi:10.1016/j.vaccine.2009.03.080 · Cited by 82 · see citing works

Antibody-Mediated Protection against Mucosal Simian-Human Immunodeficiency Virus Challenge of Macaques Immunized with Alphavirus Replicon Particles and Boosted with Trimeric Envelope Glycoprotein in MF59 Adjuvant

Barnett, S. W., Burke, B., Sun, Y., Kan, E., Legg, H., Lian, Y., Bost, K., Zhou, F., Goodsell, A., zur Megede, J., et al. (2010) · Journal of Virology · doi:10.1128/jvi.02533-09 · Cited by 82 · see citing works

Immune responses against a liver-stage malaria antigen induced by simian adenoviral vector AdCh63 and MVA prime–boost immunisation in non-human primates

Capone, S., Reyes‐Sandoval, A., Naddeo, M., et al. (2010) · Vaccine · doi:10.1016/j.vaccine.2010.10.041 · Cited by 77 · see citing works

Enhancing Blood-Stage Malaria Subunit Vaccine Immunogenicity in Rhesus Macaques by Combining Adenovirus, Poxvirus, and Protein-in-Adjuvant Vaccines

Draper, S. J., Biswas, S., Spencer, A. J., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1001760 · Cited by 77 · see citing works

Long peptides induce polyfunctional T cells against conserved regions of HIV‐1 with superior breadth to single‐gene vaccines in macaques

Rosario, M., Bridgeman, A., Quakkelaar, E. D., Quigley, M. F., Hill, B. J., Knudsen, M. L., Ammendola, V., Ljungberg, K., Borthwick, N., Im, E., et al. (2010) · European Journal of Immunology · doi:10.1002/eji.201040344 · Cited by 75 · see citing works

Route of Adenovirus-Based HIV-1 Vaccine Delivery Impacts the Phenotype and Trafficking of Vaccine-Elicited CD8 + T Lymphocytes

Kaufman, D. R., Bivas‐Benita, M., Simmons, N. L., Miller, D. D., & Barouch, D. H. (2010) · Journal of Virology · doi:10.1128/jvi.02563-09 · Cited by 66 · see citing works

Boosting BCG with Recombinant Modified Vaccinia Ankara Expressing Antigen 85A: Different Boosting Intervals and Implications for Efficacy Trials

Pathan, A. A., Sander, C. R., Fletcher, H. A., et al. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001052 · Cited by 64 · see citing works

Potent immune responses and in vitro pro-inflammatory cytokine suppression by a novel adenovirus vaccine vector based on rare human serotype 28

Kahl, C. A., Bonnell, J. C., Hiriyanna, S., Fultz, M., Nyberg-Hoffman, C., Chen, P., King, C. R., & Gall, J. G. D. (2010) · Vaccine · doi:10.1016/j.vaccine.2010.06.050 · Cited by 57 · see citing works

Overview of vaccines and vaccination

Ada, G. (2005) · Molecular Biotechnology · doi:10.1385/mb:29:3:255 · Cited by 51 · see citing works

Vaccination with an Adenoviral Vector That Encodes and Displays a Retroviral Antigen Induces Improved Neutralizing Antibody and CD4+T-Cell Responses and Confers Enhanced Protection

Bayer, W., Tenbusch, M., Lietz, R., Johrden, L., Schimmer, S., Überla, K., Dittmer, U., & Wildner, O. (2009) · Journal of Virology · doi:10.1128/jvi.01840-09 · Cited by 48 · see citing works

A preliminary and comparative evaluation of a novel Ad5 [E1-, E2b-] recombinant-based vaccine used to induce cell mediated immune responses

Gabitzsch, E. S., Xu, Y., Yoshida, L. H., Balint, J. P., Gayle, R. B., Amalfitano, A., & Jones, F. R. (2008) · Immunology Letters · doi:10.1016/j.imlet.2008.11.003 · Cited by 41 · see citing works

Robust Vaccine-Elicited Cellular Immune Responses in Breast Milk following Systemic Simian Immunodeficiency Virus DNA Prime and Live Virus Vector Boost Vaccination of Lactating Rhesus Monkeys

Wilks, A. B., Christian, E., Seaman, M. S., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1002751 · Cited by 34 · see citing works

Gene-based vaccines: Recent developments.

Liu, M. A. (2010) · PubMed · Cited by 31 · see citing works

Adenovirus 5‐ and 35‐based immunotherapy enhances the strength but not breadth or quality of immunity during chronic SIV infection

Soloff, A. C., Liu, X., Gao, W., et al. (2009) · European Journal of Immunology · doi:10.1002/eji.200839130 · Cited by 22 · see citing works

CD8+ Cell Anti-HIV Activity Rapidly Increases Upon Discontinuation of Early Antiretroviral Therapy

Killian, M. S., Roop, J. I., Ng, S., et al. (2009) · Journal of Clinical Immunology · doi:10.1007/s10875-009-9275-y · Cited by 12 · see citing works

A guide to vaccinology: from basic principles to new developments

Pollard, A. J., & Bijker, E. M. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-020-00479-7 · Cited by 1,593 · see citing works

Application and development of viral vectors in neural stem cells

Li, L., Sun, C., Wang, X. B., et al. (2018) · Int J Genet · doi:10.3760/cma.j.issn.1673-4386.2018.06.013

Research Progress in Viral Vectors of Cancer Gene Therapy

Xiang-min, S. (2014) · Medical Recapitulate

Use of HIV as a gene transfer vector.

Pluta, K., & Kacprzak, M. (2009) · Acta Biochimica Polonica · doi:10.18388/abp.2009_2490 · Cited by 69 · see citing works

Progress in the Nonviral Vectors of Gene Therapy

Ping, W. (2005) · Progress in Veterinary Medicine

Use of multiply deleted adenovirus vectors to probe adenovirus vector performance and toxicities.

Amalfitano, A. (2003) · PubMed · Cited by 8 · see citing works