The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.
Linalool bioactive properties and potential applicability in drug delivery systems
Abstract
The medicinal properties of essential oils from aromatic plants are known since antiquity. Currently, the technological innovation enabled the reinvention of the ancient plant knowledge leading to the identification and extraction of organic compounds present in essential oils. These organic compounds belong mainly to the terpene group and are accountable for the wide range of bioactive properties attributed to essential oils. Linalool (C10H18O), so-called 3,7-dimethyl-1,6-octadien-3-ol, is a monoterpene alcohol broadly present as a major constituent of plant essential oils, particularly lavender and coriander. Linalool per se is non-toxic and, according to recent in vitro and in vivo scientific studies, it has demonstrated to have a comprehensive range of bioactive properties, which can be exploited for pharmaceutic and cosmetic applications. The present review focuses on the anti-inflammatory, anticancer, anti-hyperlipidemic, antimicrobial, antinoceptive, analgesic, anxiolytic, antidepressive and neuroprotective properties of linalool. The advantages of the loading in nanotechnology-based drug delivery systems, with the purpose of enhancing its bioactive properties are also discussed.
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Cited by
Koilybayeva, M., Shynykul, Z., Ustenova, G., Waleron, K., Jońca, J., Mustafina, K., Amirkhanova, A., Koloskova, Y., Bayaliyeva, R., Akhayeva, T., et al. (2023) · Molecules · doi:10.3390/molecules28227556 · Cited by 44
Monoterpenoid biosynthesis by engineered microbes
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Metadata
- Authors
- Pereira, I., Severino, P., Santos, A. C., Silva, A. M., & Souto, E. B.
- Venue
- Colloids and Surfaces B: Biointerfaces
- Publisher
- Elsevier BV
- Published
- 2018-11
- Volume
- 171
- Pages
- 566-578
- ISSN
- 0927-7765 (ISSN-L)
- OpenAlex
- W2885676094
- Cited by
- 267
- References
- 110
- FWCI
- 17.89
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pereira, I., Severino, P., Santos, A. C., Silva, A. M., & Souto, E. B. (2018). Linalool bioactive properties and potential applicability in drug delivery systems. Colloids and Surfaces B: Biointerfaces. https://doi.org/10.1016/j.colsurfb.2018.08.001
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