Prefrontal control of fear: more than just extinction
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- The mouse dorsal peduncular cortex encodes fear memoryRodrigo Campos‐Cardoso, Zephyr R. Desa, Brianna L. Fitzgerald, Alana G Moore, Jace L Duhon, Victoria A. Landar, Roger L. Clem, Kirstie A. Cummings · 2024 · Cell Reports
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- Calcium signalling in medial intercalated cell dendrites and spinesCornelia Strobel, R Sullivan, Peter Gregory Stratton, Pankaj Sah · 2017 · The Journal of Physiology
- Increased amygdalar metabotropic glutamate receptor 7 mRNA in a genetic mouse model of impaired fear extinctionRichard M. O’Connor, Cian P. McCafferty, Javier A. Bravo, Nicolas Singewald, Andrew Holmes, John F. Cryan · 2018 · Psychopharmacology
- Impairment of the context preexposure facilitation effect in juvenile rats by neonatal alcohol exposure is associated with decreased Egr-1 mRNA expression in the prefrontal cortex.Sarah A. Jablonski, Patrese A. Robinson-Drummer, William B. Schreiber, Arun Asok, Jeffrey B. Rosen, Mark E. Stanton · 2018 · Behavioral Neuroscience
- Contextual fear response is modulated by M-type K+ channels and is associated with subtle structural changes of the axon initial segment in hippocampal GABAergic neuronsSara Melisa Arciniegas Ruiz, Eliav Tikochinsky, Vardit Rubovitch, Chaim G. Pick, Bernard Attali · 2023 · AIMS neuroscience
- Ventral Pallidum and Amygdala Cooperate to Restrain Reward Approach under ThreatAlejandra Hernández-Jaramillo, Elizabeth Illescas-Huerta, Francisco Sotres-Bayón · 2024 · Journal of Neuroscience
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- Beyond Fear, Extinction, and Freezing: Strategies for Improving the Translational Value of Animal Conditioning ResearchChristopher K. Cain · 2023 · Current topics in behavioral neurosciences
- Neural oscillations in the infralimbic cortex after electrical stimulation of the amygdala. Relevance to acute stress processingAina Luque‐García, Vicent Teruel‐Martí, Sergio Martínez‐Bellver, Albert Adell, Ana Cervera‐Ferri, Joana Martínez‐Ricós · 2018 · The Journal of Comparative Neurology
- Involvement of cortical projections to basolateral amygdala in context-induced reinstatement of ethanol-seeking in ratsGabrielle Emily Boaventura Tavares, P Bianchi, Thais Suemi Yokoyama, Paola Palombo, Fábio C. Cruz · 2023 · Behavioural Brain Research
- Long-range GABAergic neurons in the prefrontal cortex modulate behaviorChristian Bravo-Rivera, María M. Diehl, Ciorana Roman-Ortiz, Jose Rodríguez-Romaguera, Luis E. Rosas-Vidal, Héctor Bravo-Rivera, Kelvin Quiñones-Laracuente, Fabricio H Do Monte · 2014 · Journal of Neurophysiology
- Theoretical Tinnitus Multimodality Framework: A Neurofunctional ModelIman Ghodratitoostani, Alexandre C. B. Delbem, Mohammad Torabi-Nami, Bahador Makkiabadi, Hamid Jalilvand, Tanit Ganz Sánchez · 2016 · Journal of Advanced Medical Sciences and Applied Technologies
- Extinction of Contextual Fear with Timed Exposure to Enriched Environment: A Differential EffectP. Hegde, S. O'Mara, T. Laxmi · 2017 · Annals of Neurosciences
- The formation and extinction of fear memory in tree shrewsShujiang Shang, Cong Wang, Chengbing Guo, Xu‐Feng Huang, Liecheng Wang, Chen Zhang · 2015 · Frontiers in Behavioral Neuroscience
- Medial prefrontal cortex (A32 and A25) projections in the common marmoset: a subcortical anterograde studyJ. A. Ríos-Flórez, R. R. M. Lima, P. L. A. Morais, Helder Henrique Alves de Medeiros, J. S. Cavalcante, E. S. Nascimento · 2021 · Scientific Reports
- Lateral Orbitofrontal Cortical Modulation on the Medial Prefrontal Cortex-Amygdala Pathway: Differential Regulation of Intra-Amygdala GABAA and GABAB ReceptorsChun‐hui Chang · 2017 · The International Journal of Neuropsychopharmacology
- Inhibitory modulation of medial prefrontal cortical activation on lateral orbitofrontal cortex–amygdala information flowChun‐hui Chang, Ta‐wen Ho · 2017 · The Journal of Physiology
- Inhibition of Serotonin Reuptake in the Medial Prefrontal Cortex during Acquisition of a Condition Reflex Fear Reaction Promotes Formation of Generalized FearNatalia B. Saulskaya, О. Э. Марчук · 2020 · Neuroscience and Behavioral Physiology
- Neuroimaging and intervening in memory reconsolidation of human drug addictionChuan Gang Fan, Yan Fen Cheng, Huixing Gou, Chang Liu, Shengliang Deng, Chialun Liu, Xianwen Chen, Junjie Bu, Xiaochu Zhang · 2020 · Science China Information Sciences
- Conceptual advances in the cognitive neuroscience of learning: Implications for relational frame theoryNigel A. Vahey, Marc Bennett, Robert Whelan · 2017 · Journal of Contextual Behavioral Science
- Reduced Inhibitory Inputs On Basolateral Amygdala Principal Neurons Following Long-Term Alcohol ConsumptionPaul M. Klenowski, Matthew Joseph Fogarty, Joy R. Drieberg-Thompson, Mark C. Bellingham, Selena E. Bartlett · 2020 · Neuroscience
- Brain Mechanisms for Learning and Using Safety SignalsAllison R. Foilb, John P. Christianson · 2018 · Elsevier eBooks
- Dissociable dorsal medial prefrontal cortex ensembles are necessary for cocaine seeking and fear conditioning in miceShuai Liu, Natalie N. Nawarawong, Xiaojie Liu, Qing-song Liu, Christopher M. Olsen · 2024 · Translational Psychiatry
- Axon initial segment dynamics during associative fear learningChloé Maëlle Benoit, Dan A Ganea, Ricardo Paricio-Montesinos, Julia Esser, Christian Thome, Jan Maximilian Janssen, Andrea Sattin, Sabrina Milena Innocenti, Sabine Krabbe, Andreas Lüthi et al. · 2025 · Nature Neuroscience
- Plexin-A1 expression in the inhibitory neurons of infralimbic cortex regulates the specificity of fear memory in male miceXin Ran Cheng, Yan Zhao, Shuyu Zheng, Panwu Zhao, Jinlin Zou, Wei‐Jye Lin, Wen Wu, Xiaojing Ye · 2021 · Neuropsychopharmacology
- Prefrontal Cortex in Learning to Overcome Generalized FearEdward Korzus · 2015 · Journal of Experimental Neuroscience
- Selective expression of the neurexin substrate for presenilin in the adult forebrain causes deficits in associative memory and presynaptic plasticityAna C. Sánchez-Hidalgo, Francisco Arias-Aragón, María Teresa Romero-Barragán, Celia Martín-Cuevas, Jose Maria Delgado-Garcia, Amalia Martı́nez-Mir, Francisco G. Scholl · 2021 · Experimental Neurology
- Honey bees can store and retrieve independent memory traces after complex experiences that combine appetitive and aversive associationsMartín Klappenbach, Agustín E. Lara, Fernando Federico Locatelli · 2022 · Journal of Experimental Biology
- Reduction of Excitatory Synaptic Transmission Efficacy in the Infralimbic Prefrontal Cortex Potentially Contributes to Impairment of Contextual Fear Memory Extinction in Aged MiceQiang Shan, Xiaoxuan Yu, Yao Tian · 2022 · The Journals of Gerontology Series A
- Medial Prefrontal Cortex Processes Threatening Stimuli in Juvenile RatsPatricia Kabitzke, Gordon A. Barr, Thomas Chan, Harry N. Shair, Christoph P. Wiedenmayer · 2014 · Neuropsychopharmacology
- Acute tianeptine treatment selectively modulates neuronal activation in the central nucleus of the amygdala and attenuates fear extinctionBill P. Godsil, Bruno Bontempi, François Mailliet, Philippe Delagrange, Michael Spedding, Thérèse M. Jay · 2015 · Molecular Psychiatry
- Fear Models in Animals and HumansCatherine A. Hartley, Elizabeth A. Phelps · 2013 · Springer eBooks
- Functional Interplay of Type-2 Corticotrophin Releasing Factor and Dopamine Receptors in the Basolateral Amygdala-Medial Prefrontal Cortex CircuitryHéctor E. Yarur, Juan Zegers, Ignacio Vega‐Quiroga, J Novoa, Francisco Ciruela, Marı́a Estela Andrés, Katia Gysling · 2020 · The International Journal of Neuropsychopharmacology
- Chemogenetic activation of the ventral subiculum–BNST pathway reduces context fear expressionLeeza Kopaeva, Alexandrina Yakimov, Louise Urien, Elizabeth P. Bauer · 2023 · Learning & Memory
- Involvement of dysregulated hippocampal histone H3K9 methylation at the promoter of the BDNF gene in impaired memory extinctionKenichi Oga, Manabu Fuchikami, Hironori Kobayashi, Tatsuhiro Miyagi, Sho Fujita, S. Fujita, S. Okada, Shigeru Morinobu · 2024 · Psychopharmacology
- The locus coeruleus influences behavior by coordinating effective integration of fear memories and sensory inputHaoyu Duan, Tianyu Wang, Xinyang Zhang, Dan Xia, Zeyi Wang, Tsz Hei Fong, Tianxiang Li, Rongzhen Yan, Yang Zhan, Yulong Li et al. · 2025 · PLoS Biology
- Medial prefrontal cortex circuit dynamics involved in stage-specific addictionZhao Dongdong, Xianwen Zhang, Jie Bai · 2025 · Brain Structure and Function
- Chronic exposure to imipramine induces a switch from depression-like to mania-like behavior in female serotonin transporter knockout rats: Role of BDNF signaling in the infralimbic cortexMina Sadighi, Lingling Mai, Yifan Xu, Morgane Boillot, Giorgia Targa, Francesca Mottarlini, Paolo Brambilla, Peter Gass, Lucia Caffino, Fabio Fumagalli et al. · 2024 · Journal of Affective Disorders
- Auditory Fear Conditioning Alters Sensitivity of the Medial Prefrontal Cortex but this is not based on Frequency-dependent IntegrationHaiting Xie, Duobin Wu, Xiaoya Gao, Ningqian Wang, Zhongju Xiao · 2020 · Neuroscience
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- Genetics in Experimental Psychopathology: From Laboratory Models to Therapygenetics. Where do we go from Here?Tina B. Lonsdorf, Johanna M.P. Baas · 2015 · Psychopathology Review
- Animal Models to Investigate Social Support Induced Anxiety ReductionsSreeparna Majumdar, Elizabeth A. Lungwitz, Katharine D. Andrews, Joanna E. Chambers, William A. Truitt · 2018 · Elsevier eBooks
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- Cathodal transcranial direct current stimulation on the prefrontal cortex applied after reactivation attenuates fear memories and prevent reinstatement after extinctionJohanna Marcela Duran, Rodrigo O. Sierra, Karen Corredor, Fernando P. Cárdenas · 2021 · Journal of Psychiatric Research
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- Chronic treatment with corticosterone increases the number of tyrosine hydroxylase-expressing cells within specific nuclei of the brainstem reticular formationCarla Letizia Busceti, Domenico Bucci, Mariarosaria Scioli, Paola Di Pietro, Ferdinando Nicoletti, Stefano Puglisi‐Allegra, Michela Ferrucci, Francesco Fornai · 2022 · Frontiers in Neuroanatomy
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- Punishment history biases corticothalamic responses to motivationally-significant stimuliFederica Lucantonio, Zhi-Xiao Su, Anna J. Chang, Bilal A. Bari, Jeremiah Y. Cohen · 2020 · bioRxiv
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- Selective disruption of perineuronal nets in mice lacking Crtl1 is sufficient to make fear memories susceptible to erasureAndrea Poli, Aurelia Viglione, Raffaele Mario Mazziotti, Silvia Morea, Riccardo Melani, Davide Silingardi, Elena Putignano, Nicoletta Berardi, Tommaso Pizzorusso · 2022 · Research Square
- The infralimbic and prelimbic cortical areas bidirectionally regulate safety learning during normal and stress conditionsAda C. Felix‐Ortiz, Jaelyn M. Terrell, Carolina Gonzalez, Hope D. Msengi, Angelica R. Ramos, Miranda B. Boggan, Savannah M. Lopez-Pesina, Gabrielle Magalhães, Anthony Burgos-Robles · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Subcortical functional connectivity alterations in first-episode medication-naïve adolescents with major depressive disorderLei Sun, Zilin Zhou, Ruohan Feng, Yingxue Gao, Weijie Bao, Hong He, Hongwei Li, Xinyue Hu, Hailong Li, Lianqing Zhang et al. · 2025 · European Child & Adolescent Psychiatry
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- Activation of Beta-adrenergic Receptors Upregulates the Signal-to-Noise Ratio of Auditory Input in the Medial Prefrontal Cortex and Mediates Auditory Fear ConditioningHaiting Xie, Yueqin Tian, Zhongli Li, Kaitao Wang, Runtong Li, Shang Yi, Aimin Chen, Jian Chen, Jun Liu, Xuhong Wei et al. · 2023 · Molecular Neurobiology
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