The DOI matches its Crossref record; 54 of the 55 references it cites were found in a registry or an index.
Chain elongation in anaerobic reactor microbiomes to recover resources from waste
Open accessAbstract
Different microbial pathways can elongate the carbon chains of molecules in open cultures of microbial populations (i.e. reactor microbiomes) under anaerobic conditions. Here, we discuss three such pathways: 1. homoacetogenesis to combine two carbon dioxide molecules into acetate; 2. succinate formation to elongate glycerol with one carbon from carbon dioxide; and 3. reverse β oxidation to elongate short-chain carboxylates with two carbons into medium-chain carboxylates, leading to more energy-dense and insoluble products (e.g. easier to separate from solution). The ability to use reactor microbiomes to treat complex substrates can simultaneously address two pressing issues: 1. providing proper waste management; and 2. producing renewable chemicals and fuels.
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Cites
Biogas production: current state and perspectives
Weiland, P. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-009-2246-7 · Cited by 2,824
Microbial electrosynthesis — revisiting the electrical route for microbial production
Rabaey, K., & Rozendal, R. A. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2422 · Cited by 1,676
Self-citationWaste to bioproduct conversion with undefined mixed cultures: the carboxylate platform
Agler, M. T., Wrenn, B. A., Zinder, S. H., & Angenent, L. T. (2010) · Trends in biotechnology · doi:10.1016/j.tibtech.2010.11.006 · Cited by 821
Self-citationAlternative Pathways of Carbon Dioxide Fixation: Insights into the Early Evolution of Life?
Fuchs, G. (2011) · Annual Review of Microbiology · doi:10.1146/annurev-micro-090110-102801 · Cited by 726
The genome of Clostridium kluyveri , a strict anaerobe with unique metabolic features
Seedorf, H., Fricke, W. F., Veith, B., Brüggemann, H., Liesegang, H., Strittmatter, A., Miethke, M., Buckel, W., Hinderberger, J., Li, F., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711093105 · Cited by 506
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Werner, J. J., Knights, D., García, M. L., Scalfone, N. B., Smith, S., Yarasheski, K. E., Cummings, T. A., Beers, A. R., Knight, R. D., & Angenent, L. T. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015676108 · Cited by 493
Self-citationSteinbusch, K. J. J., Hamelers, H. V. M., Plugge, C. M., & Buisman, C. J. N. (2011) · Energy Environ. Sci. · doi:10.1039/c0ee00282h · Cited by 453
Electrosynthesis of Commodity Chemicals by an Autotrophic Microbial Community
Marshall, C. W., Ross, D. E., Fichot, E. B., Norman, R. S., & May, H. D. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.02401-12 · Cited by 423
Tracy, B. P., Jones, S. W., Fast, A. G., Indurthi, D. C., & Papoutsakis, E. T. (2011) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2011.10.008 · Cited by 408
Chain elongation with reactor microbiomes: upgrading dilute ethanol to medium-chain carboxylates
Agler, M. T., Spirito, C. M., Usack, J. G., Werner, J. J., & Angenent, L. T. (2012) · Energy & Environmental Science · doi:10.1039/c2ee22101b · Cited by 376
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Chain elongation with reactor microbiomes: open-culture biotechnology to produce biochemicals
Angenent, L. T., Richter, H., Buckel, W., Spirito, C. M., Steinbusch, K. J. J., Plugge, C. M., Strik, D. P. B. T. B., Grootscholten, T. I. M., Buisman, C. J. N., & Hamelers, H. V. M. (2016) · Environmental Science & Technology · doi:10.1021/acs.est.5b04847 · Cited by 689
Self-citationKehrein, P., van Loosdrecht, M. C. M., Osseweijer, P., Garfí, M., Dewulf, J. P., & Posada, J. A. (2020) · Environmental Science Water Research & Technology · doi:10.1039/c9ew00905a · Cited by 499
Liew, F., Martin, M. E., Tappel, R. C., Heijstra, B. D., Mihalcea, C., & Köpke, M. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00694 · Cited by 485
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Anaerobic fermentation for n-caproic acid production: A review
Cavalcante, W. D. A., Leitão, R. C., Gehring, T. A., Angenent, L. T., & Santaella, S. T. (2016) · Process Biochemistry · doi:10.1016/j.procbio.2016.12.024 · Cited by 373
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Metadata
- Authors
- Spirito, C. M., Richter, H., Rabaey, K., Stams, A. J., & Angenent, L. T.
- Affiliations
- Cornell University (US)
- Ghent University (BE)
- Wageningen University & Research (NL)
- Corresponding author
- Angenent, Largus T
- Venue
- Current Opinion in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2014-06
- Volume
- 27
- Pages
- 115-122
- ISSN
- 0958-1669 (ISSN-L)
- OpenAlex
- W2111185205
- Cited by
- 479
- References
- 55
- Citations by year
- 2026: 56 · 2025: 48 · 2024: 56 · 2023: 46 · 2022: 46 · 2021: 59 · 2020: 43 · 2019: 34 · 2018: 24 · 2017: 31 · 2016: 19 · 2015: 15 · 2014: 1
- FWCI
- 4.04
- Type
- journal article
- Language
- en
- Open access
- green
- research.wur.nl
- Locations
- Current Opinion in Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Socio-Environmental Systems Modeling (acceptedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, cc-by-nc-nd)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- U. S. Army Research Office (W911NF-12-1-0555)
- Cornell University Agricultural Experiment Station (NYC-123452)
- National Institutes for Food and Agriculture (NIFA)
- U.S. Department of Agriculture
- European Research Council Starter Grant Electrotalk
- the Multidisciplinary Research Partnership Ghent Bio-Economy
- Netherlands Science Foundation (CW-TOP 700.55.343)
- European Research Council (323009)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Anaerobic Digestion and Biogas Production
- Physical Sciences › Environmental Science › Environmental Engineering › Microbial Fuel Cells and Bioremediation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Keywords
- chain extension, homoacetogenesis, reverse β-oxidation, CO2 utilization, glycerol, waste management, renewable chemicals, renewable fuels, microbial metabolism
- MeSH terms
- Acetates, Anaerobiosis, Carbon Dioxide, Carboxylic Acids, Electrodes, Oxidation-Reduction, Waste Management, Bioreactors, Succinic Acid, Recycling, Microbiota
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