The DOI matches its Crossref record; 124 of the 130 references it cites were found in a registry or an index.
A review of opioid dependence treatment: Pharmacological and psychosocial interventions to treat opioid addiction
Abstract
Opioid dependence is a problem of national concern, especially with dramatically increased rates of abuse and dependence of prescription opioids. The current article provides an up-to-date review of the literature on opioid dependence treatment, with a focus on conclusions drawn by experts in the field (e.g., Cochrane reviews and meta-analyses) and methodologically rigorous studies (e.g., randomized controlled trials). We describe the major classes of drug treatments available, including opioid agonist (e.g., methadone, buprenorphine, LAAM), antagonist (e.g., naltrexone) and non-opioid pharmacotherapies (e.g., alpha2 adrenergic agonists). These treatments are discussed in the context of detoxification and long term treatment options such as abstinence-based and maintenance strategies. We review the state of the literature as to prevention of opioid overdose and discuss the widespread problem of comorbidity among opioid-dependent populations. We also focus prominently on evidence for inclusion of psychosocial approaches in treatment regimens, either as stand-alone or in conjunction with psychopharmacological options.
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In the citing paper
“There is a dearth of research investigating the efficacy of psychosocial treatments in reducing opioid use among people living with chronic pain.42,43”
Citations
Cites
2 retracted
Psychosocial treatment for opiate abuse and dependence
Mayet, S., Farrell, M., Ferri, M., Amato, L., & Davoli, M. (2004) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004330.pub2 · Cited by 106
RetractedPsychosocial treatment for opiate abuse and dependence
Mayet, S., Farrell, M., Ferri, M., Davoli, M., & Amato, L. (2003) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004330 · Cited by 12
RetractedMonitoring the Future: National Results on Adolescent Drug Use: Overview of Key Findings
Johnston, L. D., O’Malley, P. M., Bachman, J. G., & Schulenberg, J. E. (2003) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1037/e560352009-001 · Cited by 6,930
Di Chiara, G., & Imperato, A. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.14.5274 · Cited by 4,733
Relapse Prevention: Maintenance Strategies in the Treatment of Addictive Behaviors
Washton, A. M. (1986) · Journal of Studies on Alcohol · doi:10.15288/jsa.1986.47.260 · Cited by 2,531
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
Mattick, R. P., Breen, C. L., Kimber, J., & Davoli, M. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002207.pub4 · Cited by 2,312
Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence
Mattick, R. P., Breen, C., Kimber, J., & Davoli, M. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002209.pub2 · Cited by 1,654
Volume, I. I. (2017) · Institute for Social Research eBooks · doi:10.3998/2027.42/139710 · Cited by 1,369
A Meta-Analytic Review of Psychosocial Interventions for Substance Use Disorders
Dutra, L., Stathopoulou, G., Basden, S. L., Leyro, T. M., Powers, M. B., & Otto, M. W. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06111851 · Cited by 1,287
Results from the 2003 National Survey on Drug Use and Health: National Findings
(2004) · PsycEXTRA Dataset · doi:10.1037/e400442005-001 · Cited by 1,245
Research works printed but not linked: 2
- Johnston, 2008, Monitoring the future national survey results on drug use, 1975–2007, Vol. 1.
- Maremmani, 2003, Dual diagnosis heroin addicts. The clinical and therapeutic aspects, Heroin Addiction and Related Clinical Problems, 5, 7
Cited by
Sorted by citations
Medication-Assisted Treatment of Opioid Use Disorder
Connery, H. S. (2015) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000075 · Cited by 577
Stigma at every turn: Health services experiences among people who inject drugs
Paquette, C. E., Syvertsen, J. L., & Pollini, R. A. (2018) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2018.04.004 · Cited by 504
Treatment of substance abusing patients with comorbid psychiatric disorders
Kelly, T. M., Daley, D. C., & Douaihy, A. B. (2011) · Addictive Behaviors · doi:10.1016/j.addbeh.2011.09.010 · Cited by 306
Prescription Opioid Misuse, Abuse, and Treatment in the United States: An Update
Brady, K. T., McCauley, J. L., & Back, S. E. (2015) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2015.15020262 · Cited by 249
Bonhomme, J. J. E., Shim, R. S., Gooden, R., Tysu, D., & Rust, G. S. (2012) · Journal of the National Medical Association · doi:10.1016/s0027-9684(15)30175-9 · Cited by 233
Metadata
- Authors
- Veilleux, J. C., Colvin, P. J., Anderson, J., York, C., & Heinz, A. J.
- Affiliations
- University of Illinois Chicago (US)
- Corresponding author
- Veilleux, Jennifer C.
- Venue
- Clinical Psychology Review
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 30
- Issue
- 2
- Pages
- 155-166
- ISSN
- 0272-7358 (ISSN-L)
- OpenAlex
- W2038833041
- Cited by
- 336
- References
- 130
- Citations by year
- 2026: 2 · 2025: 12 · 2024: 11 · 2023: 13 · 2022: 21 · 2021: 12 · 2020: 24 · 2019: 62 · 2018: 24 · 2017: 22 · 2016: 18 · 2015: 24 · 2014: 29 · 2013: 22 · 2012: 20
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Psychology Review (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- opioid use disorder, opioid dependence treatment, pharmacological interventions, psychosocial interventions, methadone, buprenorphine, LAAM, naltrexone, alpha-2 adrenergic agonists, opioid agonists, opioid antagonists, opioid detoxification, abstinence-based treatment, maintenance therapy, opioid overdose prevention, comorbidities, prescription opioid abuse
- MeSH terms
- Biofeedback, Psychology, Humans, Narcotic Antagonists, Opioid-Related Disorders, Narcotics, Self-Help Groups, Cognitive Behavioral Therapy, Prevalence, Adrenergic Agents
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