Cited by 345Opioid Use Disorder TreatmentSubstance Abuse Treatment and OutcomesPain Management and Opioid Use

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A review of opioid dependence treatment: Pharmacological and psychosocial interventions to treat opioid addiction

Veilleux, Jennifer C., Colvin, Peter J., Anderson, Jennifer, York, Catherine, Heinz, Adrienne J.·2010·Clinical Psychology Review

DOI 10.1016/j.cpr.2009.10.006

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Abstract

Opioid dependence is a problem of national concern, especially with dramatically increased rates of abuse and dependence of prescription opioids. The current article provides an up-to-date review of the literature on opioid dependence treatment, with a focus on conclusions drawn by experts in the field (e.g., Cochrane reviews and meta-analyses) and methodologically rigorous studies (e.g., randomized controlled trials). We describe the major classes of drug treatments available, including opioid agonist (e.g., methadone, buprenorphine, LAAM), antagonist (e.g., naltrexone) and non-opioid pharmacotherapies (e.g., alpha2 adrenergic agonists). These treatments are discussed in the context of detoxification and long term treatment options such as abstinence-based and maintenance strategies. We review the state of the literature as to prevention of opioid overdose and discuss the widespread problem of comorbidity among opioid-dependent populations. We also focus prominently on evidence for inclusion of psychosocial approaches in treatment regimens, either as stand-alone or in conjunction with psychopharmacological options.

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Psychosocial treatment for opiate abuse and dependence
Mayet, S., Farrell, M., Ferri, M., Davoli, M., & Amato, L. (2003) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004330 · Cited by 12
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Authors: Veilleux, J. C., Colvin, P. J., Anderson, J., York, C., & Heinz, A. J.
Affiliations: University of Illinois Chicago (US)
Corresponding author: Veilleux, Jennifer C.
ORCID: Veilleux, Jennifer C.
Heinz, Adrienne J.
Venue: Clinical Psychology Review
Publisher: Elsevier BV
Published: 2010-03
Volume: 30
Issue: 2
Pages: 155-166
ISSN: 0272-7358 (ISSN-L)
DOI: 10.1016/j.cpr.2009.10.006
OpenAlex: W2038833041
Cited by: 336
References: 130
Citations by year: 2026: 2 · 2025: 12 · 2024: 11 · 2023: 13 · 2022: 21 · 2021: 12 · 2020: 24 · 2019: 62 · 2018: 24 · 2017: 22 · 2016: 18 · 2015: 24 · 2014: 29 · 2013: 22 · 2012: 20
FWCI: 1.81
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Clinical Psychology Review (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Keywords: opioid use disorder, opioid dependence treatment, pharmacological interventions, psychosocial interventions, methadone, buprenorphine, LAAM, naltrexone, alpha-2 adrenergic agonists, opioid agonists, opioid antagonists, opioid detoxification, abstinence-based treatment, maintenance therapy, opioid overdose prevention, comorbidities, prescription opioid abuse
MeSH terms: Biofeedback, Psychology, Humans, Narcotic Antagonists, Opioid-Related Disorders, Narcotics, Self-Help Groups, Cognitive Behavioral Therapy, Prevalence, Adrenergic Agents

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A review of opioid dependence treatment: Pharmacological and psychosocial interventions to treat opioid addiction

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