A pragmatic multi-centred randomised controlled trial of yoga for chronic low back pain: trial protocol
Open accessAbstract
UNLABELLED: A systematic review revealed three small randomised controlled trials of yoga for low back pain, all of which showed effects on back pain that favoured the yoga group. To build on these studies a larger trial, with longer term follow-up, and a number of different yoga teachers delivering the intervention is required. This study protocol describes the details of a randomised controlled trial (RCT) to determine the effectiveness and cost-effectiveness of Yoga for chronic Low Back Pain, which is funded by Arthritis Research Campaign (arc) and is being conducted by the University of York. 262 patients will be recruited from GP practices in 5 centres in England. Patients will be randomised to receive usual care or 12 weekly classes of yoga. A yoga programme will be devised that can be delivered by yoga teachers of the two main national yoga organisations in the UK (British Wheel of Yoga and Iyengar Yoga Association (UK)). TRIAL REGISTRATION: Current controlled trials registry ISRCTN81079604 (date registered 30/03/2007).
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The protocol for this systematic review was published previously by these authors.
“The protocol for this study was published previously by these authors.8”
From Productivity outcomes from chronic pain management interventions in the working age population; a systematic review (2024) · cites this paper as [8]
The Abstract identifies this paper as the protocol for a randomised controlled trial of yoga for chronic low back pain, not a systematic review. The Background mentions a systematic review the authors undertook, but does not present a protocol for it. The verbatim citing sentence says only “this study”; the supplied claim’s identification of that study as a systematic review is what the source contradicts. (LLM, conf=0.86)
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Cites
A Study of the Natural History of Back Pain: Part I
ROLAND, M., & MORRIS, R. (1983) · Spine · doi:10.1097/00007632-198303000-00004 · Cited by 3,395 · see citing works
The Roland–Morris Disability Questionnaire and the Oswestry Disability Questionnaire
Roland, M. O., & Fairbank, J. C. T. (2000) · Spine · doi:10.1097/00007632-200012150-00006 · Cited by 1,913 · see citing works
Manca, A., Hawkins, N., & Sculpher, M. J. (2005) · Health Economics · doi:10.1002/hec.944 · Cited by 1,024 · see citing works
Costs, effects and C/E‐ratios alongside a clinical trial
van Hout, B. A., Al, M., Gordon, G. S., & Rutten, F. (1994) · Health Economics · doi:10.1002/hec.4730030505 · Cited by 963 · see citing works
Cost‐effectiveness acceptability curves – facts, fallacies and frequently asked questions
Fenwick, E. A. L., OʼBrien, B. J., & Briggs, A. H. (2004) · Health Economics · doi:10.1002/hec.903 · Cited by 946 · see citing works
Assessing health-related quality of life in patients with sciatica
Patrick, D. L., Deyo, R. A., Atlas, S. J., Singer, D. E., Chapin, A., & Keller, R. B. (1995) · Spine · doi:10.1097/00007632-199509000-00011 · Cited by 760 · see citing works
Hoch, J. S., Briggs, A. H., & Willan, A. R. (2002) · Health Economics · doi:10.1002/hec.678 · Cited by 535 · see citing works
UK BEAM Trial Team (2004) · BMJ · doi:10.1136/bmj.38282.669225.ae · Cited by 517 · see citing works
Development and Testing of the UK SF-12
Jenkinson, C., & Layte, R. (1997) · Journal of Health Services Research & Policy · doi:10.1177/135581969700200105 · Cited by 493 · see citing works
Measuring the Functional Status of Patients With Low Back Pain
Beurskens, A. J. H. M., de Vet, H. C. W., Köke, A. J. A., van der Heijden, G. J. M. G., & Knipschild, P. G. (1995) · Spine · doi:10.1097/00007632-199505000-00008 · Cited by 491 · see citing works
Comparing Yoga, Exercise, and a Self-Care Book for Chronic Low Back Pain
Sherman, K. J., Cherkin, D. C., Erro, J. H., Miglioretti, D. L., & Deyo, R. A. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-143-12-200512200-00003 · Cited by 477 · see citing works
UK population norms for EQ-5DPreprint
Kind, P., Hardman, G., & Macran, S. (1999) · RePEc: Research Papers in Economics · Cited by 442 · see citing works
Willan, A. R., Briggs, A. H., & Hoch, J. S. (2004) · Health Economics · doi:10.1002/hec.843 · Cited by 364 · see citing works
Effect of Iyengar yoga therapy for chronic low back pain
Williams, K. A., Petronis, J. J., Smith, D. J., Goodrich, D. E., Wu, J., Ravi, N., Doyle, E. J., Juckett, G., Kolar, M. M., Gross, R. T., et al. (2005) · Pain · doi:10.1016/j.pain.2005.02.016 · Cited by 333 · see citing works
Understanding controlled trials: What is a patient preference trial?
Torgerson, D. J., & Sibbald, B. (1998) · BMJ · doi:10.1136/bmj.316.7128.360 · Cited by 306 · see citing works
Minimal clinically important difference. Low back pain: outcome measures.
Bombardier, C., Hayden, J. A., & Beaton, D. (2001) · PubMed · Cited by 298 · see citing works
The impact of modified Hatha yoga on chronic low back pain: a pilot study.
Galantino, M. L., Bzdewka, T. M., Eissler-Russo, J. L., Holbrook, M. L., Mogck, E. P., Geigle, P. M., & Farrar, J. T. (2004) · PubMed · Cited by 253 · see citing works
Active Exercise, Education, and Cognitive Behavioral Therapy for Persistent Disabling Low Back Pain
Johnson, R. E., Jones, G. T., Wiles, N., Chaddock, C., Potter, R., Roberts, C., Symmons, D. P. M., Watson, P., Torgerson, D. J., & Macfarlane, G. J. (2007) · Spine · doi:10.1097/brs.0b013e318074f890 · Cited by 194 · see citing works
Developing a Valid and Reliable Measure of Health Outcome for Patients With Low Back Pain
Ruta, D. A., Garratt, A., Wardlaw, D., & Russell, I. T. (1994) · Spine · doi:10.1097/00007632-199409000-00004 · Cited by 188 · see citing works
Measuring the functional status of patients with low back pain.
Ra, D. (1988) · PubMed · Cited by 150 · see citing works
Manca, A., Rice, N., Sculpher, M. J., & Briggs, A. H. (2004) · Health Economics · doi:10.1002/hec.914 · Cited by 117 · see citing works
Bigos, S. J., Roland, M., Waddell, G., Moffett, J. K., Burton, K. A., & Main, C. J. (1996) · Cited by 112 · see citing works
Manca, A., Rice, N., Sculpher, M. J., & Briggs, A. (2005) · ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) · Cited by 23 · see citing works
Flagged first, then by citations
2 of the 25 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- [14]Nicholas MK. Self-efficacy and chronic pain. Paper presented at the annual conference of the British Psychological Society. St. Andrews; 1989.
- [15]Torgerson D.J. Sibbald B. What is a patient preference design? BMJ 316 1998 36 PMC2665528 9487173
Cited by
Sorted by citations
Sample size calculations for pilot randomized trials: a confidence interval approach
Cocks, K., & Torgerson, D. J. (2013) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2012.09.002 · Cited by 431 · see citing works
A Randomized Trial Comparing Yoga, Stretching, and a Self-care Book for Chronic Low Back Pain
Sherman, K. J. (2011) · Archives of Internal Medicine · doi:10.1001/archinternmed.2011.524 · Cited by 297 · see citing works
Yoga treatment for chronic non-specific low back pain
Wieland, L. S., Skoetz, N., Pilkington, K., Vempati, R., D’Adamo, C. R., & Berman, B. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010671.pub2 · Cited by 258 · see citing works
Yoga for Chronic Low Back Pain
Tilbrook, H. E., Cox, H., Hewitt, C. E., Kang'ombe, A. R., Chuang, L., Jayakody, S., Aplin, J., Semlyen, A., Trewhela, A., Watt, I. S., et al. (2011) · Annals of Internal Medicine · doi:10.7326/0003-4819-155-9-201111010-00003 · Cited by 242 · see citing works
Guidelines for Developing Yoga Interventions for Randomized Trials
Sherman, K. (2012) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2012/143271 · Cited by 172 · see citing works
Mediators of Yoga and Stretching for Chronic Low Back Pain
Sherman, K. J., Wellman, R., Cook, A. J., Cherkin, D. C., & Ceballos, R. M. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/130818 · Cited by 96 · see citing works
A Pragmatic Multicentered Randomized Controlled Trial of Yoga for Chronic Low Back Pain
Chuang, L., Soares, M. O., Tilbrook, H. E., Cox, H., Hewitt, C. E., Aplin, J., Semlyen, A., Trewhela, A., Watt, I. S., & Torgerson, D. J. (2012) · Spine · doi:10.1097/brs.0b013e3182545937 · Cited by 72 · see citing works
Yoga for chronic non-specific low back pain
Wieland, L. S., Skoetz, N., Pilkington, K., Harbin, S., Vempati, R., & Berman, B. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010671.pub3 · Cited by 69 · see citing works
Man, M., Tilbrook, H. E., Jayakody, S., Hewitt, C. E., Cox, H., Cross, B., & Torgerson, D. J. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.10.013 · Cited by 34 · see citing works
Ngowsiri, K., Tanmahasamut, P., & Sukonthasab, S. (2014) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2014.05.002 · Cited by 32 · see citing works
Tilbrook, H. E., Hewitt, C. E., Aplin, J., Semlyen, A., Trewhela, A., Watt, I. S., & Torgerson, D. J. (2013) · Physiotherapy · doi:10.1016/j.physio.2013.10.001 · Cited by 21 · see citing works
Chowdhury, A. R., Graham, P. L., Schofield, D., Costa, D. S. J., & Nicholas, M. (2024) · Pain · doi:10.1097/j.pain.0000000000003149 · Cited by 15 · see citing works
Bhatta, M., Patil, S. S., Yadav, S. S., Somanadhapai, S., & Thapa, R. (2024) · Journal of Ayurveda and Integrative Medicine · doi:10.1016/j.jaim.2024.101030 · Cited by 9 · see citing works
Yoga as an Alternative and Complementary Treatment for Patients With Low Back Pain
Sharma, M., & Haider, T. (2012) · Journal of Evidence-Based Complementary & Alternative Medicine · doi:10.1177/2156587212458693 · Cited by 9 · see citing works
Brinzo, J. A., Crenshaw, J. T., Thomas, L., & Sapp, A. (2016) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2016-2409 · Cited by 6 · see citing works
Ward, L., Stebbings, S. M., Athens, J., Cherkin, D. C., & Baxter, D. G. (2014) · Physical Therapy Reviews · doi:10.1179/1743288x14y.0000000139 · Cited by 4 · see citing works
Peat, G., Jordan, K. P., Wilkie, R., van der Windt, D., Yu, D., Narle, G., & Ali, N. (2022) · Journal of Public Health · doi:10.1093/pubmed/fdac014 · Cited by 1 · see citing works
Bağcıer, F. (2020) · BOĞAZİÇİ TIP DERGİSİ · doi:10.14744/bmj.2020.92486 · Cited by 1 · see citing works
DuCharme, A. (2015) · SUNY Digital Repository Support (State University of New York System)
Aplicação das práticas integrativas e complementares na odontologia: revisão integrativa
Budach, F. A., dos Santos, G. L., Silva, G. M. C. D., Silva, I. R. G., Pimentel, B. V., Goya, S., Fujimaki, M., & Lolli, L. F. (2022) · Brazilian Journal of Development · doi:10.34117/bjdv8n12-075
Loudon, A. (2013) · Figshare · doi:10.25959/23205761
- Authors
- Cox, H., Tilbrook, H., Aplin, J., Chuang, L.-H., Hewitt, C., Jayakody, S., Semlyen, A., Soares, M. O., Torgerson, D., Trewhela, A., Watt, I., & Worthy, G.
- Affiliations
- University of York (GB)
- University of Manchester (GB)
- Corresponding author
- Tilbrook, Helen
- ORCID
- Venue
- Complementary Therapies in Clinical Practice
- Publisher
- Elsevier BV
- Published
- 2010-05
- Volume
- 16
- Issue
- 2
- Pages
- 76-80
- ISSN
- 1744-3881 (ISSN-L)
- PMC
- PMC2856861
- OpenAlex
- W2157081180
- Cited by
- 21
- References
- 25
- Citations by year
- 2024: 2 · 2022: 3 · 2020: 1 · 2017: 1 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 3 · 2012: 4
- FWCI
- 1.68
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Complementary Therapies in Clinical Practice (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- Versus Arthritis (17727)
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Health Sciences › Medicine › Complementary and alternative medicine › Acupuncture Treatment Research Studies
- Keywords
- yoga, chronic low back pain, yoga teachers, Iyengar yoga, cost-effectiveness, pain management, exercise therapy
- MeSH terms
- Adolescent, Adult, Aged, Chronic Disease, Clinical Protocols, England, Humans, Middle Aged, Research Design, Yoga, Single-Blind Method, Low Back Pain, Young Adult
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