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Cited by 256

The DOI matches its Crossref record; 102 of the 102 references it cites were found in a registry or an index.

Cell Size Control in Bacteria

Open access
Chien, An-Chun, Hill, Norbert S., Levin, Petra Anne·2012·Current Biology
DOI 10.1016/j.cub.2012.02.032
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Abstract

Like eukaryotes, bacteria must coordinate division with growth to ensure cells are the appropriate size for a given environmental condition or developmental fate. As single-celled organisms, nutrient availability is one of the strongest influences on bacterial cell size. Classic physiological experiments conducted over four decades ago first demonstrated that cell size is directly correlated with nutrient source and growth rate in the Gram-negative bacterium Salmonella typhimurium. This observation subsequently served as the basis for studies revealing a role for cell size in cell cycle progression in a closely related organism, Escherichia coli. More recently, the development of powerful genetic, molecular, and imaging tools has allowed us to identify and characterize the nutrient-dependent pathway responsible for coordinating cell division and cell size with growth rate in the Gram-positive model organism B. subtilis. Here, we discuss the role of cell size in bacterial growth and development and propose a broadly applicable model for cell size control in this important and highly divergent domain of life.

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Metadata

Authors
Chien, A.-C., Hill, N. S., & Levin, P. A.
Venue
Current Biology
Publisher
Elsevier BV
Published
2012-05
Volume
22
Issue
9
Pages
R340-R349
ISSN
0960-9822 (ISSN-L)
DOI
10.1016/j.cub.2012.02.032
OpenAlex
W2102670556
Cited by
256
References
102
FWCI
10.98
Type
journal article
Language
en
Open access
bronze

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