The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
An overview of IL-17 function and signaling
Open accessAbstract
Since the discovery of interferons over 50 years ago, efforts to understand the biochemistry, molecular biology and biological activities of cytokines have been intense and rewarding. Although there are several hundred cytokines and receptors currently recognized, they in fact fall into a fairly limited set of subfamilies (reviewed in [1, 2]). Within these families (and in some cases even outside them), cytokines share many structural and functional features that have provided a framework for understanding their biological activities and signal transduction mechanisms. This review will focus on interleukin (IL)-17, the founding member of the newest subclass of cytokines, which has received considerable attention in the last several years due to its central role in the Th17 system.
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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
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“IL-17 and IL-17F exist as homodimers [9], and it was recently shown that IL-17A and IL-17F, which are both pro-”
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Cited by
Reboldi, A., Coisne, C., Baumjohann, D., Benvenuto, F., Bottinelli, D., Lira, S., Uccelli, A., Lanzavecchia, A., Engelhardt, B., & Sallusto, F. (2009) · Nature Immunology · doi:10.1038/ni.1716 · Cited by 1,206
Conti, H. R., Shen, F., Nayyar, N., Stocum, E., Sun, J. N., Lindemann, M. J., Ho, A. W., Hai, J. H., Yu, J. J., Jung, J. W., et al. (2009) · Journal of Experimental Medicine · doi:10.1084/jem.20081463 · Cited by 1,024
Neutrophils: Cinderella of innate immune system
Kumar, V., & Sharma, A. (2010) · International Immunopharmacology · doi:10.1016/j.intimp.2010.08.012 · Cited by 444
Protumor vs Antitumor Functions of IL-17
Murugaiyan, G., & Saha, B. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901017 · Cited by 369
Infection, Inflammation, and Bone Regeneration: a Paradoxical Relationship
Thomas, M. V., & Puleo, D. A. (2011) · Journal of Dental Research · doi:10.1177/0022034510393967 · Cited by 329
Metadata
- Authors
- Gaffen, S. L.
- Venue
- Cytokine
- Publisher
- Elsevier BV
- Published
- 2008-09
- Volume
- 43
- Issue
- 3
- Pages
- 402-407
- ISSN
- 1043-4666 (ISSN-L)
- OpenAlex
- W2008924149
- Cited by
- 382
- References
- 24
- FWCI
- 15.71
- Type
- journal article
- Language
- en
- Open access
- green
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