The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.
Protumor vs Antitumor Functions of IL-17
Open accessAbstract
Inflammation appears to be a necessity for both metastasis and elimination of tumor cells. IL-17, a proinflammatory cytokine produced by Th17 cells, contributes to both the processes by playing a dual role in the antitumor immunity. On one hand, IL-17 promotes an antitumor cytotoxic T cell response leading to tumor regression. On the other hand, by facilitating angiogenesis and egress of tumor cells from the primary focus, IL-17 promotes tumor growth. Thus, the therapeutic application that uses IL-17 needs to be refined by minimizing its protumor functions.
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Cited by
The polarization of immune cells in the tumour environment by TGFβ
Flavell, R. A., Sanjabi, S., Wrzesinski, S. H., & Licona-Limón, P. (2010) · Nature Reviews Immunology · doi:10.1038/nri2808 · Cited by 940
When worlds collide: Th17 and Treg cells in cancer and autoimmunity
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Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
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Th17 cells are long lived and retain a stem cell-like molecular signature
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Metadata
- Authors
- Murugaiyan, G., & Saha, B.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-10-01
- Volume
- 183
- Issue
- 7
- Pages
- 4169-4175
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W2166609587
- Cited by
- 369
- References
- 108
- FWCI
- 10.31
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
