The transforming growth factor-β superfamily of receptors

TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders

Massagué, J., Blain, S. W., & Lo, R. S. (2000) · Cell · doi:10.1016/s0092-8674(00)00121-5 · Cited by 2,391

Mechanism of activation of the TGF-β receptor

Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., & Massagué, J. (1994) · Nature · doi:10.1038/370341a0 · Cited by 2,340

Transcriptional control by the TGF‐β/Smad signaling system

Massagué, J., & Wotton, D. (2000) · The EMBO Journal · doi:10.1093/emboj/19.8.1745 · Cited by 1,990

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

Nakao, A., Afrakhte, M., Morn, A., Nakayama, T., Christian, J. L., Heuchel, R. L., Itoh, S., Kawabata, M., Heldin, N., Heldin, C., et al. (1997) · Nature · doi:10.1038/39369 · Cited by 1,796

SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7

Inman, G. J., Nicolás, F. J., Callahan, J. F., Harling, J. D., Gaster, L. M., Reith, A. D., Laping, N. J., & Hill, C. S. (2002) · Molecular Pharmacology · doi:10.1124/mol.62.1.65 · Cited by 1,636

Regulation of myostatin activity and muscle growth

Lee, S.-J., & McPherron, A. C. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.151270098 · Cited by 1,616

TGFβ signals through a heteromeric protein kinase receptor complex

Wrana, J. L., Attisano, L., Cárcamo, J. M., Zentella‐Dehesa, A., Doody, J. F., Laiho, M., Wang, X.-F., & Massagué, J. (1992) · Cell · doi:10.1016/0092-8674(92)90395-s · Cited by 1,528

Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

Arber, S., Barbayannis, F. A., Hanser, H., Schneider, C., Stanyon, C. A., Bernard, O., & Caroni, P. (1998) · Nature · doi:10.1038/31729 · Cited by 1,426

Active and Inactive Protein Kinases: Structural Basis for Regulation

Johnson, L. N., Noble, M. E. M., & Owen, D. J. (1996) · Cell · doi:10.1016/s0092-8674(00)81092-2 · Cited by 1,396

Thymus Transcriptome of TGF-β Superfamily

Jurberg, A. D., & Cotta-de-Almeida, V. (2019) · Springer eBooks · doi:10.1007/978-3-030-12040-5_11 · Cited by 1

Non-collagenous ECM Matrix Components Growth Factors and Cytokines Involved in Matrix Mineralization

Merkel, A. C., Guirado, E., Narayanan, K., Ganapathy, A., & George, A. (2021) · Biology of extracellular matrix · doi:10.1007/978-3-030-76283-4_4 · Cited by 1

Development of an in Vitro Assay to Assess Gap Junction Activity in Cumulus-Oocyte Complexes (COC) in the Rat

Patel, S. B. (2009) · doi:10.26686/wgtn.16967377 · Cited by 1

Energy Metabolism in Skeletal Muscle and its Link to Insulin Resistance

Wang, M. (2011) · Wiley eBooks · doi:10.1002/9780470910016.ch6 · Cited by 1

The Potential of Neurotrophic Factors for the Treatment of Parkinson’s Disease

Aideen, M. E., & Toulouse, A. (2011) · InTech eBooks · doi:10.5772/16659 · Cited by 1

Adenovirus-mediated overexpression of activin βC subunit accelerates liver regeneration in partially hepatectomized rats

Taub, R. A. (2005) · Journal of Hepatology · doi:10.1016/j.jhep.2005.07.011 · Cited by 1

Molecular and morphological studies of folliculogenesis, oocyte maturation and embryogenesis in humans.

Lindeberg, M. (2008) · Figshare · Cited by 1

An investigation into the roles of p53, Nodal/ Activin and fibroblast growth factor signalling in early heart development

Black, S. (2016) · ORCA Online Research @Cardiff (Cardiff University) · Cited by 1

RBP4 functions as an antagonistic ligand of orphan DR6Preprint

Kim, T., Lee, W., Nguyen, T. N. C., Jang, J., Kim, K., Kim, M., Seo, D., Lee, Y.-S., & Lee, Y.-I. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.21.619555 · Cited by 1

Caractérisation de voies de régulation paracrine potentiellement impliquées dans le devenir des cellules souches spermatogoniales chez la truite arc-en-ciel (Oncorhynchus mykiss)

Maouche, A. (2018) · doi:10.70675/72de05abz744az4972z9bdczc356c657cd1b · Cited by 1

Modulating TGF-β Receptor Signaling: A Novel Approach of Cancer Therapy

Naumann, U., & Weller, M. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-293-9_39

TRANSFORMING GROWTH FACTOR BETA (TGF-β) FAMILY OF MOLECULES

McAnulty, R. J. (2006) · Elsevier eBooks · doi:10.1016/b0-12-370879-6/00394-x

MYOSTATIN AND TGF-Β FUNCTION IN THE REGULATION OF MYOGENESIS IN RAINBOW TROUT (Oncorhynchus mykiss), A BASAL TELEOST

Jaffe, I. M. (2013) · doi:10.23860/thesis-jaffe-ian-2013

Avaliação da expressão de hepcidina e produção de IL-6 por monócitos de indivíduos idosos

Miranda, J. C. (2009) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.60.2009.tde-25082009-152450

Other signaling pathways

Nagy, I., Lever, I. J., & Cibelli, M. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511781933.005

Transforming growth factor receptor type II (ec-TβR II) behaves as a halophile

Saini, K., Khan, M. A. I., Chakrapani, S., & Deep, S. (2014) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2014.09.051

Transforming Growth Factor Signaling in Colorectal Cancer

Grady, W. M. (2007)

Influence of Previous Moderate Training on the Elevated Serum Levels of Growth Factors and Inflammatory Mediators in Rats Exposed to Acute Exhausting Physical Exercise

Naguib, Y. M., & Azmy, R. M. (2014) · American Journal of Medicine and Medical Sciences

Le Transforming Growth Factor-beta (TGF-β) : une cytokine de plus en plus impliquée dans la physiopathogénie des maladies pulmonaires, fibroses en particulier

Sauty, A., & Aubert, J. (2005) · Revue des Maladies Respiratoires · doi:10.1016/s0761-8425(05)72917-x

Investigating the Role of Retinoblastoma Protein and Transforming Growth Factor-Beta in Growth Inhibition

Amiri, M. (2014) · Scholarship@Western (Western University)

The role of transforming growth factor beta-receptor III in Kawasaki Disease

Lundergan, J. E. (2011) · eScholarship (California Digital Library)

Regulation of the Neuronal Chloride Cotransporter KCC2 by Neurotrophins

Thomas-Crusells, J. (2004) · Työväentutkimus Vuosikirja

Characterization of Bone Morphogenetic Protein 7 in Breast Cancer

Alarmo, E. (2008) · Tampere University Institutional Repository (Tampere University)

Calibrating Notch/TGF-β Signaling for Youthful, Healthy Tissue Maintenance and Repair

Carlson, M. E., & Conboy, I. M. (2010) · Springer eBooks · doi:10.1007/978-90-481-3999-6_13

Tumor Necrosis Factors and Chemokines in Hair Development

Lefebvre, S. (2012) · Työväentutkimus Vuosikirja

Studies on TGF-β family signalling in the diseased lung tissue

Leppäranta, O. (2012) · Työväentutkimus Vuosikirja

Two Activin Type 2B Receptors from Sea Bream Function Similarly in vitro

Nadjar-Boger, E., Krol, E., & Funkenstein, B. (2016) · Biological Bulletin · doi:10.1086/bblv230n1p56

Hematopoietic growth factors

Ihle, J. N. (2006) · Cambridge University Press eBooks · doi:10.1017/cbo9780511471001.006

Expression und Wirkung von Erythropoietin während der Retinaentwicklung der Maus

Scheerer, N. (2011) · DuEPublico (University of Duisburg-Essen)

Importância dos fatores de crescimento locais na regulação da foliculogênese ovariana em mamíferos Importance of local growth factors in the regulation of ovarian folliculogenesis in mammals

Leitão, C. C. F., Leitão, F., Brito, I. R., Frota, I. M. A., Frota, A., & Silva, J. R. V. (2009)

Activin is critical for the development of pain hypersensitivity after inflammation.

Xu, P. (2007) · OhioLink ETD Center (Ohio Library and Information Network)

Transforming growth factor-beta1 activation and transforming growth factor-beta receptor 2 expression levels in the regulation of the TGF-beta signaling pathway

Rojas, A. (2008) · Europe PMC (PubMed Central)

Principles and Mechanisms of Morphogenesis and Dysmorphogenesis

Schoenwolf, G. C., Bleyl, S. B., Brauer, P. R., & Francis‐West, P. H. (2009) · Elsevier eBooks · doi:10.1016/b978-0-443-06811-9.10005-3

Altered Airway Smooth Muscle Contractile Function in the Presence of Airway Epithelium and the Influence of TGF-β1

Tjong, J. (2017) · DalSpace (Dalhousie University)

Inmunoexpresión del factor de crecimiento transformante β3 (TGF-β3) y del receptor III del factor de crecimiento transformante β (TGF β-RIII) en pacientes pediátricos con paladar hendido completo o incompleto no sindromático

González, C. L., Martínez, H. A. M., López, S. G., Ramírez, M. D. C. R., López‐Casillas, F., González, A. P., & Valdez, D. H. G. (2017) · Revista Mexicana de Ortodoncia · doi:10.1016/j.rmo.2018.01.003

Immunoexpression of transforming growth factor-β3 (TGF-β3) and receptor III of β transforming growth factor (TGF β-RIII) in pediatric patients with complete or incomplete non-syndromic cleft palate

González, C. L., Martínez, H. A. M., López, S. G., Ramírez, M. D. C. R., López‐Casillas, F., González, A. P., & Valdez, D. H. G. (2017) · Revista Mexicana de Ortodoncia · doi:10.1016/j.rmo.2018.01.012

Signal Transduction Mechanisms for Lysophosphatidic Acid Mediated Cardiac Differentiation of P19 Stem Cells

Maan, G. (2018) · University of Hertfordshire Research Archive (University of Hertfordshire) · doi:10.18745/th.21151

Genetic polymorphism in core promoter sequence of ACTRIIB gene and association analysis with growth traits in chicken

Vishnu, P. G., Bhattacharya, T. K., Bhushan, B., Paswan, C., Prasad, A. R., & Divya, D. (2019) · Reproduction in Domestic Animals · doi:10.1111/rda.13511

Molekulargenetik des Marfan-Syndroms

Rommel, K. (2006) · Institutional Repository of Leibniz Universität Hannover (Leibniz Universität Hannover) · doi:10.15488/6787

La voie du TGFβ

Robert, J. (2010) · Springer eBooks · doi:10.1007/978-2-8178-0028-8_6

Transforming Growth Factor-β (TGF-β) Family of Molecule

McAnulty, R. J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-08-102723-3.00007-x

The conditioned medium from a stable human GDF3-expressing CHO cell line, induces the differentiation of PC12 cells

Wu, Q., Ling, J., ZhangXianmei, M., & Yu, Y. (2012)

Experimental Animal Models in Cranial Suture Biology: Molecular and Pharmacological Treatment Strategies

Rachwalski, M. (2021) · Springer eBooks · doi:10.1007/978-3-030-72338-5_19

Dies1 gene expression and regulation in gastric cancer

Reis, I. (2014) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.34626/ntv9-2c13

TGF-β (BETA) AND PERIOSTIN MODULATE EACH OTHER’S EXPRESSION IN BOTH BREAST STROMA AND TUMOR CELLS

Burman, A. D. (2013)

Biomineralization and Bone Regeneration

Hu, J., Liu, X., & Ma, P. X. (2008) · Elsevier eBooks · doi:10.1016/b978-012369410-2.50045-0

Relacion entre los polimorfismos funcionales de nucleotido unico del TGF-β1 y el glaucoma primario de angulo abierto en una poblacion mexicana

Alvarado-Castillo, B., Navarro‐Partida, J., Ori-Guy, T., García-Loza, B. A., Carvajal-Quinonez, M. A., Navarro-Arregui, D., & Cruz-Pavlovich, F. J. S. (2022) · Revista Mexicana de Oftalmología · doi:10.24875/rmo.m22000240

Different responses of the TGF-β superfamily genes in the warm-water noble scallop Chlamys nobilis to acute and chronic low temperature stress

Liu, S., Cheng, D., Chen, M., Li, H., Zhao, N., Liu, Y., Yan, B., Wang, W., Zhang, H., & Zheng, H. (2025) · Aquaculture · doi:10.1016/j.aquaculture.2025.742852

TGF-ß Signaling Pathway and Colorectal Cancer

Grady, W. M. (2013) · Springer eBooks · doi:10.1007/978-1-4614-8412-7_7

Characterization of TGFβ Signaling Components in Large Yellow Croaker (Larimichthys crocea) and Their Role in Growth and Body Shape Regulation

Jiang, X., Zhang, L., Hu, X., Cui, M., Li, J., Liu, H., & Yao, L. (2025) · Journal of Marine Science and Engineering · doi:10.3390/jmse13091716

Activin A Secreted by Cancer-Associated Fibroblasts Reduces the Sensitivity of Breast Cancer Cells to Ixazomib via Inhibition of Proteasome Activity

Geng, S., Liu, S., He, L., Wang, S., Niu, Y., Gao, J., Meng, Y., & Gao, M. (2025) · Biomolecules · doi:10.3390/biom15091318

The Role of Bone Morphogenetic Protein (BMP)-12 in Accelerating Tendon Healing

Lee, S. C. (2025) · Clinical Pain · doi:10.35827/cp.2025.24.2.94

Advances in Internal Organogenesis: Differentiation and Morphogenesis of Human Ventral Cavity Organs

Qureshi, M. I., Mian, A. A., & Khan, I. (2026) · Stem Cell Reviews and Reports · doi:10.1007/s12015-025-11041-0

Ectodysplasin-A (EDA) Signaling Cross-Talk in Skeletogenesis

Ahi, E. P., Moustakas-Verho, J. E., & Singh, P. (2026) · Calcified Tissue International · doi:10.1007/s00223-026-01502-0 · Cited by 1

Influence des facteurs biochimiques et mécaniques in vitro sur la prolifération cellulaire et la synthèse matricielle de fibroblastes : application en Ingénierie tissulaire

Fawzi-Grancher, S. (2006) · doi:10.70675/d90bd60bz9269z455czafa4zf7daee51972e

Différenciation des cellules souches embryonnaires humaines en cellules épithéliales respiratoires.

Navarre, A. (2016) · theses.fr (ABES) · doi:10.70675/cb95c371zdf96z4569za402za35116916f8a

The role of Activin signaling pathway in the initiation and progression of pancreatic cancer

Zhao, Y. (2019) · theses.fr (ABES) · doi:10.70675/17612dbdz6d94z4563z86a3z6d1e91b34f9b

Incidences de l’ischémie cérébrale sur la fonction et la sensibilité cardiaques à l’ischémie

Méloux, A. (2019) · theses.fr (ABES) · doi:10.70675/a9b30413z16cbz4038za961z28b244223160

Le rôle de l'érythroferrone dans la régulation du métabolisme du fer

Sardo, U. (2020) · theses.fr (ABES) · doi:10.70675/d03e67aczc44bz4af9z8fa1zef080668f44f

Protection et dégradation du muscle squelettique : caractérisation des propriétés antioxydantes du Safran et impact de l’hypermuscularité dans la protéolyse post-mortem

Nassar, R. (2020) · theses.fr (ABES) · doi:10.70675/a5fdec16z9885z4cfezb824z9bcf174c3888

Bases génétiques du déterminisme du sexe chez le tilapia du Nil en populations naturelles

Triay, C. (2021) · doi:10.70675/eb748549z374bz4020zbe2cz56bd9cbdc19a

The impact of serum myokine profile on the outcome of peritoneal dialysis patients

Xu, L., Ng, J. K., Chan, G. C., Fung, W. W., Pang, W., Chow, K., & Szeto, C. (2026) · BMC Nephrology · doi:10.1186/s12882-026-05170-y

Advances in self-assembling growth factor-mimetic peptides for regenerative medicine

Yao, C., Wu, X., Wei, M., & Shi, J. (2026) · Journal of Controlled Release · doi:10.1016/j.jconrel.2026.115334

Signal transduction and TGF-β superfamily receptors

Kolodziejczyk, S. M., & Hall, B. K. (1996) · Biochemistry and Cell Biology · doi:10.1139/o96-033 · Cited by 32

Transforming Growth Factor-β Receptors and Signal Transduction

Miyazono, K., ten Dijke, P., Souchelnytskyi, S., Nakao, A., Imamura, T., Hanai, J., Kawabata, M., & Heldin, C. (1997) · Springer eBooks · doi:10.1007/978-1-4612-1874-6_26 · Cited by 2

Receptors for the TGF-β superfamily: multiple polypeptides and serine/threonine kinases

Lin, H. Y.-F., & Lodish, H. F. (1993) · Trends in Cell Biology · doi:10.1016/0962-8924(93)90195-7 · Cited by 163

TGF-beta receptors: structure and function.

Lin, H. Y.-F., & Moustakas, A. (1994) · PubMed · Cited by 63

Receptor–Ligand Recognition in the TGFβ Family as Suggested by the Crystal Structures of BMP-2–BR-IAec and TGFβ3–TR-IIec

Dreyer, M. (2003) · Elsevier eBooks · doi:10.1016/b978-012124546-7/50411-3