The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.
Resting‐state network dysfunction in Alzheimer's disease: A systematic review and meta‐analysis
Open accessAbstract
Introduction: We performed a systematic review and meta‐analysis of the Alzheimer's disease (AD) literature to examine consistency of functional connectivity alterations in AD dementia and mild cognitive impairment, using resting‐state functional magnetic resonance imaging. Methods: Studies were screened using a standardized procedure. Multiresolution statistics were performed to assess the spatial consistency of findings across studies. Results: Thirty‐four studies were included (1363 participants, average 40 per study). Consistent alterations in connectivity were found in the default mode, salience, and limbic networks in patients with AD dementia, mild cognitive impairment, or in both groups. We also identified a strong tendency in the literature toward specific examination of the default mode network. Discussion: Convergent evidence across the literature supports the use of resting‐state connectivity as a biomarker of AD. The locations of consistent alterations suggest that highly connected hub regions in the brain might be an early target of AD.
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Imaging the evolution and pathophysiology of Alzheimer disease
Jagust, W. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0067-3 · Cited by 604
Synaptic degeneration in Alzheimer disease
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The role of the medial prefrontal cortex in cognition, ageing and dementia
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Metadata
- Authors
- Badhwar, A., Tam, A., Dansereau, C., Orban, P., Hoffstaedter, F., & Bellec, P.
- Venue
- Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
- Publisher
- Wiley
- Published
- 2017-01
- Volume
- 8
- Issue
- 1
- Pages
- 73-85
- ISSN
- 2352-8729 (ISSN-L)
- OpenAlex
- W2606081028
- Cited by
- 438
- References
- 101
- FWCI
- 3.72
- Type
- journal article
- Language
- en
- Open access
- gold
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- Badhwar, A., Tam, A., Dansereau, C., Orban, P., Hoffstaedter, F., & Bellec, P. (2017). Resting‐state network dysfunction in Alzheimer's disease: A systematic review and meta‐analysis. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. https://doi.org/10.1016/j.dadm.2017.03.007
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