The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Oral vaccination of fish: Lessons from humans and veterinary species
Open accessAbstract
The limited number of oral vaccines currently approved for use in humans and veterinary species clearly illustrates that development of efficacious and safe oral vaccines has been a challenge not only for fish immunologists. The insufficient efficacy of oral vaccines is partly due to antigen breakdown in the harsh gastric environment, but also to the high tolerogenic gut environment and to inadequate vaccine design. In this review we discuss current approaches used to develop oral vaccines for mass vaccination of farmed fish species. Furthermore, using various examples from the human and veterinary vaccine development, we propose additional approaches to fish vaccine design also considering recent advances in fish mucosal immunology and novel molecular tools. Finally, we discuss the pros and cons of using the zebrafish as a pre-screening animal model to potentially speed up vaccine design and testing for aquaculture fish species.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Frey, A., Giannasca, K. T., Weltzin, R., Giannasca, P. J., Reggio, H., Lencer, W. I., & Neutra, M. R. (1996) · The Journal of experimental medicine · doi:10.1084/jem.184.3.1045 · Cited by 401
Long-lived effects of administering β-glucans: Indications for trained immunity in fish
Petit, J., & Wiegertjes, G. F. (2016) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2016.03.003 · Cited by 196
Adenoviruses as gene/vaccine delivery vectors: Promises and pitfalls
Appaiahgari, M. B., & Vrati, S. (2015) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2015.993374 · Cited by 110
Cited by
Sustainable aquaculture requires environmental‐friendly treatment strategies for fish diseases
Lieke, T., Meinelt, T., Hoseinifar, S. H., Pan, B., Straus, D. L., & Steinberg, C. E. W. (2020) · Reviews in Aquaculture · doi:10.1111/raq.12365 · Cited by 363
Metadata
- Authors
- Embregts, C. W. E., & Forlenza, M.
- Venue
- Developmental & Comparative Immunology
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 64
- Pages
- 118-137
- ISSN
- 0145-305X (ISSN-L)
- OpenAlex
- W2357716177
- Cited by
- 176
- References
- 3
- FWCI
- 5.89
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Oral vaccination of fish: Lessons from humans and veterinary species. https://app.cochat.ai/papers/10.1016/j.dci.2016.03.024
- The paper
- Embregts, C. W. E., & Forlenza, M. (2016). Oral vaccination of fish: Lessons from humans and veterinary species. Developmental & Comparative Immunology. https://doi.org/10.1016/j.dci.2016.03.024
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
