The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Rho-Kinase Directs Bazooka/Par-3 Planar Polarity during Drosophila Axis Elongation
Open accessAbstract
Summary Cell rearrangements shape the Drosophila embryo through spatially regulated changes in cell shape and adhesion. We show that Bazooka/Par-3 (Baz) is required for the planar polarized distribution of myosin II and adherens junction proteins and polarized intercalary behavior is disrupted in baz mutants. The myosin II activator Rho-kinase is asymmetrically enriched at anterior and posterior borders of intercalating cells in a pattern complementary to Baz. Loss of Rho-kinase results in expansion of the Baz domain and activated Rho-kinase is sufficient to exclude Baz from the cortex. The planar polarized distribution of Baz requires its C-terminal domain. Rho-kinase can phosphorylate this domain and inhibit its interaction with phosphoinositide membrane lipids, suggesting a mechanism by which Rho-kinase could regulate Baz association with the cell cortex. These results demonstrate that Rho-kinase plays an instructive role in planar polarity by targeting Baz/Par-3 and myosin II to complementary cortical domains.
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Cites
Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)
Kimura, K., Ito, M., Amano, M., Chihara, K., Fukata, Y., Nakafuku, M., Yamamori, B., Feng, J., Nakano, T., Okawa, K., et al. (1996) · Science · doi:10.1126/science.273.5272.245 · Cited by 2,884
Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)
Amano, M., Ito, M., Kimura, K., Fukata, Y., Chihara, K., Nakano, T., Matsuura, Y., & Kaibuchi, K. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.34.20246 · Cited by 2,008
ROCKs: multifunctional kinases in cell behaviour
Riento, K., & Ridley, A. J. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1128 · Cited by 1,941
Pulsed contractions of an actin–myosin network drive apical constriction
Martin, A. C., Kaschube, M., & Wieschaus, E. F. (2009) · Nature · doi:10.1038/nature07522 · Cited by 1,245
Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation
Bertet, C., Sulak, L., & Lecuit, T. (2004) · Nature · doi:10.1038/nature02590 · Cited by 1,020
The PAR Proteins: Fundamental Players in Animal Cell Polarization
Goldstein, B., & Macara, I. G. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.10.007 · Cited by 758
Multicellular Rosette Formation Links Planar Cell Polarity to Tissue Morphogenesis
Blankenship, J. T., Backovic, S. T., Sanny, J. S. P., Weitz, O., & Zallen, J. A. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.09.007 · Cited by 707
Self-citationMunro, E., Nance, J., & Priess, J. R. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.08.001 · Cited by 682
Myosin II Dynamics Are Regulated by Tension in Intercalating Cells
Fernandez-Gonzalez, R., Simoes, S. D. M., Röper, J.-C., Eaton, S., & Zallen, J. A. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.09.003 · Cited by 662
Self-citationThe Autosomal FLP-DFS Technique for Generating Germline Mosaics in Drosophila melanogaster
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Cited by
Hidalgo-Carcedo, C., Hooper, S., Chaudhry, S. I., Williamson, P., Harrington, K., Leitinger, B., & Sahai, E. (2011) · Nature Cell Biology · doi:10.1038/ncb2133 · Cited by 366
Tepass, U. (2012) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154033 · Cited by 334
Apical–basal polarity and the control of epithelial form and function
Buckley, C. E., & St Johnston, D. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00465-y · Cited by 295
Recapitulation of morphogenetic cell shape changes enables wound re-epithelialisation
Razzell, W., Wood, W., & Martin, P. (2014) · Development · doi:10.1242/dev.107045 · Cited by 82
Metadata
- Authors
- Simões, S. D. M., Blankenship, J. T., Weitz, O., Farrell, D. L., Tamada, M., Fernandez-Gonzalez, R., & Zallen, J. A.
- Venue
- Developmental Cell
- Publisher
- Elsevier BV
- Published
- 2010-09
- Volume
- 19
- Issue
- 3
- Pages
- 377-388
- ISSN
- 1534-5807 (ISSN-L)
- OpenAlex
- W2011233440
- Cited by
- 274
- References
- 63
- FWCI
- 8.10
- Type
- journal article
- Language
- en
- Open access
- bronze
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