Rho-Kinase Directs Bazooka/Par-3 Planar Polarity during Drosophila Axis Elongation

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

Kimura, K., Ito, M., Amano, M., Chihara, K., Fukata, Y., Nakafuku, M., Yamamori, B., Feng, J., Nakano, T., Okawa, K., et al. (1996) · Science · doi:10.1126/science.273.5272.245 · Cited by 2,884

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

Amano, M., Ito, M., Kimura, K., Fukata, Y., Chihara, K., Nakano, T., Matsuura, Y., & Kaibuchi, K. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.34.20246 · Cited by 2,008

ROCKs: multifunctional kinases in cell behaviour

Riento, K., & Ridley, A. J. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1128 · Cited by 1,941

Pulsed contractions of an actin–myosin network drive apical constriction

Martin, A. C., Kaschube, M., & Wieschaus, E. F. (2009) · Nature · doi:10.1038/nature07522 · Cited by 1,245

Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation

Bertet, C., Sulak, L., & Lecuit, T. (2004) · Nature · doi:10.1038/nature02590 · Cited by 1,020

The PAR Proteins: Fundamental Players in Animal Cell Polarization

Goldstein, B., & Macara, I. G. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.10.007 · Cited by 758

Multicellular Rosette Formation Links Planar Cell Polarity to Tissue Morphogenesis

Blankenship, J. T., Backovic, S. T., Sanny, J. S. P., Weitz, O., & Zallen, J. A. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.09.007 · Cited by 707

Cortical Flows Powered by Asymmetrical Contraction Transport PAR Proteins to Establish and Maintain Anterior-Posterior Polarity in the Early C. elegans Embryo

Munro, E., Nance, J., & Priess, J. R. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.08.001 · Cited by 682

Myosin II Dynamics Are Regulated by Tension in Intercalating Cells

Fernandez-Gonzalez, R., Simoes, S. D. M., Röper, J.-C., Eaton, S., & Zallen, J. A. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.09.003 · Cited by 662

The Autosomal FLP-DFS Technique for Generating Germline Mosaics in Drosophila melanogaster

Chou, T.-B., & Perrimon, N. (1996) · Genetics · doi:10.1093/genetics/144.4.1673 · Cited by 639

Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis

Rauzi, M., Verant, P., Lecuit, T., & Lenne, P.-F. (2008) · Nature Cell Biology · doi:10.1038/ncb1798 · Cited by 615

Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression.

Steinberg, M. S., & Takeichi, M. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.1.206 · Cited by 572

Patterned Gene Expression Directs Bipolar Planar Polarity in Drosophila

Zallen, J. A., & Wieschaus, E. (2004) · Developmental Cell · doi:10.1016/s1534-5807(04)00060-7 · Cited by 555

Drosophila Rho-Associated Kinase (Drok) Links Frizzled-Mediated Planar Cell Polarity Signaling to the Actin Cytoskeleton

Winter, C. G., Wang, B., Ballew, A., Royou, A., Karess, R., Axelrod, J. D., & Luo, L. (2001) · Cell · doi:10.1016/s0092-8674(01)00298-7 · Cited by 555

Mechanisms of convergence and extension by cell intercalation

Keller, R., Davidson, L., Edlund, A., Elul, T., Ezin, M., Shook, D., & Skoglund, P. (2000) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2000.0626 · Cited by 519

Regulation and Functions of Rho-Associated Kinase

Amano, M., Fukata, Y., & Kaibuchi, K. (2000) · Experimental Cell Research · doi:10.1006/excr.2000.5046 · Cited by 518

Drosophila Atypical Protein Kinase C Associates with Bazooka and Controls Polarity of Epithelia and Neuroblasts

Wodarz, A., Ramrath, A., Grimm, A., & Knust, E. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.150.6.1361 · Cited by 472

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

Sahai, E., & Marshall, C. J. (2002) · Nature Cell Biology · doi:10.1038/ncb796 · Cited by 466

Cell intercalation during Drosophila germband extension and its regulation by pair-rule segmentation genes

Irvine, K. D., & Wieschaus, E. (1994) · Development · doi:10.1242/dev.120.4.827 · Cited by 466

Planar Polarity and Tissue Morphogenesis

Zallen, J. A. (2007) · Cell · doi:10.1016/j.cell.2007.05.050 · Cited by 460

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1

Chen, X., & Macara, I. G. (2005) · Nature Cell Biology · doi:10.1038/ncb1226 · Cited by 458

Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts

Wodarz, A., Ramrath, A., Kuchinke, U., & Knust, E. (1999) · Nature · doi:10.1038/990128 · Cited by 451

folded gastrulation , cell shape change and the control of myosin localization

Dawes-Hoang, R. E., Parmar, K. M., Christiansen, A. E., Phelps, C. B., Brand, A. H., & Wieschaus, E. F. (2005) · Development · doi:10.1242/dev.01938 · Cited by 414

Conserved Patterns of Cell Movements during Vertebrate Gastrulation

Solnica-Krezel, L. (2005) · Current Biology · doi:10.1016/j.cub.2005.03.016 · Cited by 391

armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila.

Müller, H. A., & Wieschaus, E. (1996) · The Journal of cell biology · doi:10.1083/jcb.134.1.149 · Cited by 384

Linking Cell Cycle to Asymmetric Division: Aurora-A Phosphorylates the Par Complex to Regulate Numb Localization

Wirtz-Peitz, F., Nishimura, T., & Knoblich, J. A. (2008) · Cell · doi:10.1016/j.cell.2008.07.049 · Cited by 369

PAR-6–PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1

Nishimura, T., Yamaguchi, T., Kato, K., Yoshizawa, M., Nabeshima, Y.-I., Ohno, S., Hoshino, M., & Kaibuchi, K. (2005) · Nature Cell Biology · doi:10.1038/ncb1227 · Cited by 365

Zebrafish Rho Kinase 2 Acts Downstream of Wnt11 to Mediate Cell Polarity and Effective Convergence and Extension Movements

Marlow, F., Topczewski, J., Sepich, D., & Solnica-Krezel, L. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00864-3 · Cited by 337

Sequential Roles of Cdc42, Par-6, aPKC, and Lgl in the Establishment of Epithelial Polarity during Drosophila Embryogenesis

Hutterer, A., Betschinger, J., Petronczki, M., & Knoblich, J. A. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.05.003 · Cited by 334

aPKC Acts Upstream of PAR-1b in Both the Establishment and Maintenance of Mammalian Epithelial Polarity

Suzuki, A., Hirata, M., Kamimura, K., Maniwa, R., Yamanaka, T., Mizuno, K., Kishikawa, M., Hirose, H., Amano, Y., Izumi, N., et al. (2004) · Current Biology · doi:10.1016/j.cub.2004.08.021 · Cited by 319

The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila

Karess, R. E., Chang, X.-J., Edwards, K. A., Kulkarni, S., Aguilera, I., & Kiehart, D. P. (1991) · Cell · doi:10.1016/0092-8674(91)90013-o · Cited by 294

aPKC Phosphorylation of Bazooka Defines the Apical/Lateral Border in Drosophila Epithelial Cells

Morais-de-Sá, E., Mirouse, V., & St Johnston, D. (2010) · Cell · doi:10.1016/j.cell.2010.02.040 · Cited by 282

Reassessing the Role and Dynamics of Nonmuscle Myosin II during Furrow Formation in Early Drosophila Embryos

Royou, A., Field, C., Sisson, J. C., Sullivan, W., & Karess, R. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-06-0440 · Cited by 282

An actomyosin-based barrier inhibits cell mixing at compartmental boundaries in Drosophila embryos

Monier, B., Pélissier-Monier, A., Brand, A. H., & Sanson, B. (2010) · Nature Cell Biology · doi:10.1038/ncb2005 · Cited by 258

The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex

Mertens, A. E. E., Rygiel, T. P., Olivo, C., van der Kammen, R., & Collard, J. G. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200502129 · Cited by 238

Real-time imaging of cell-cell adherens junctions reveals that Drosophila mesoderm invagination begins with two phases of apical constriction of cells

Oda, H., & Tsukita, S. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.3.493 · Cited by 236

Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway

Roszko, I., Sawada, A., & Solnica-Krezel, L. (2009) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2009.09.004 · Cited by 234

Regulated protein–protein interaction between aPKC and PAR‐3 plays an essential role in the polarization of epithelial cells

Nagai‐Tamai, Y., Mizuno, K., Hirose, T., Suzuki, A., & Ohno, S. (2002) · Genes to Cells · doi:10.1046/j.1365-2443.2002.00590.x · Cited by 192

C. elegans PAR-3 and PAR-6 are required for apicobasal asymmetries associated with cell adhesion and gastrulation

Nance, J., Munro, E. M., & Priess, J. R. (2003) · Development · doi:10.1242/dev.00735 · Cited by 189

The PAR complex regulates pulsed actomyosin contractions during amnioserosa apical constriction in Drosophila

David, D. J. V., Tishkina, A., & Harris, T. J. C. (2010) · Development · doi:10.1242/dev.044107 · Cited by 185

Interaction between PAR-3 and the aPKC–PAR-6 complex is indispensable for apical domain development of epithelial cells

Horikoshi, Y., Suzuki, A., Yamanaka, T., Sasaki, K., Mizuno, K., Sawada, H., Yonemura, S., & Ohno, S. (2009) · Journal of Cell Science · doi:10.1242/jcs.043174 · Cited by 176

aPKC Phosphorylates Miranda to Polarize Fate Determinants during Neuroblast Asymmetric Cell Division

Atwood, S. X., & Prehoda, K. E. (2009) · Current Biology · doi:10.1016/j.cub.2009.03.056 · Cited by 175

Antero-posterior tissue polarity links mesoderm convergent extension to axial patterning

Ninomiya, H., Elinson, R. P., & Winklbauer, R. (2004) · Nature · doi:10.1038/nature02620 · Cited by 163

A Conserved Oligomerization Domain in Drosophila Bazooka/PAR-3 Is Important for Apical Localization and Epithelial Polarity

Benton, R., & Johnston, D. S. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00508-6 · Cited by 160

Rho-Kinase Phosphorylates PAR-3 and Disrupts PAR Complex Formation

Nakayama, M., Goto, T. M., Sugimoto, M., Nishimura, T., Shinagawa, T., Ohno, S., Amano, M., & Kaibuchi, K. (2008) · Developmental Cell · doi:10.1016/j.devcel.2007.11.021 · Cited by 156

Membrane Targeting of Bazooka/PAR-3 Is Mediated by Direct Binding to Phosphoinositide Lipids

Krahn, M. P., Klopfenstein, D. R., Fischer, N., & Wodarz, A. (2010) · Current Biology · doi:10.1016/j.cub.2010.01.065 · Cited by 146

Localization and requirement for Myosin II at the dorsal‐ventral compartment boundary of the Drosophila wing

Major, R. J., & Irvine, K. D. (2006) · Developmental Dynamics · doi:10.1002/dvdy.20966 · Cited by 145

The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesisPreprint

McCaffrey, L. M., & Macara, I. G. (2009) · Genes & Development · doi:10.1101/gad.1795909 · Cited by 145

Rho/Rho-associated Kinase-II Signaling Mediates Disassembly of Epithelial Apical Junctions

Samarin, S., Ivanov, A. I., Flatau, G., Parkos, C. A., & Nusrat, A. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-04-0315 · Cited by 139

Self-association of PAR-3-mediated by the Conserved N-terminal Domain Contributes to the Development of Epithelial Tight Junctions

Mizuno, K., Suzuki, A., Hirose, T., Kitamura, K., Kutsuzawa, K., Futaki, M., Amano, Y., & Ohno, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303593200 · Cited by 135

Crumbs/DaPKC-Dependent Apical Exclusion of Bazooka Promotes Photoreceptor Polarity Remodeling

Walther, R. F., & Pichaud, F. (2010) · Current Biology · doi:10.1016/j.cub.2010.04.049 · Cited by 132

aPKC Controls Microtubule Organization to Balance Adherens Junction Symmetry and Planar Polarity during Development

Harris, T., & Peifer, M. A. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.02.011 · Cited by 123

Independent cadherin–catenin and Bazooka clusters interact to assemble adherens junctions

McGill, M. A., McKinley, R. F. A., & Harris, T. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200812146 · Cited by 114

Armadillo nuclear import is regulated by cytoplasmic anchor Axin and nuclear anchor dTCF/Pan

Tolwinski, N. S., & Wieschaus, E. F. (2001) · Development · doi:10.1242/dev.128.11.2107 · Cited by 113

The Role of the Actomyosin Cytoskeleton in Coordination of Tissue Growth during Drosophila Oogenesis

Wang, Y., & Riechmann, V. (2007) · Current Biology · doi:10.1016/j.cub.2007.06.067 · Cited by 93

Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly

Chen, X., & Macara, I. (2006) · Journal of Cell Biology · doi:10.1083/jcb.200510061 · Cited by 90

Crag Regulates Epithelial Architecture and Polarized Deposition of Basement Membrane Proteins in Drosophila

Denef, N., Chen, Y., Weeks, S. D., Barcelo, G., & Schüpbach, T. (2008) · Developmental Cell · doi:10.1016/j.devcel.2007.12.012 · Cited by 87

Multicellular dynamics during epithelial elongation

Zallen, J. A., & Blankenship, J. T. (2008) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2008.01.005 · Cited by 87

Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion

Hu, H., Li, M., Labrador, J.-P., McEwen, J. M., Lai, E. C., Goodman, C. S., & Bashaw, G. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409325102 · Cited by 85

Rho Kinase's Role in Myosin Recruitment to the Equatorial Cortex of Mitotic Drosophila S2 Cells Is for Myosin Regulatory Light Chain Phosphorylation

Dean, S. O., & Spudich, J. A. (2006) · PLoS ONE · doi:10.1371/journal.pone.0000131 · Cited by 69

Actomyosin contractility and Discs large contribute to junctional conversion in guiding cell alignment within the Drosophila embryonic epithelium

Simone, R. P., & DiNardo, S. (2010) · Development · doi:10.1242/dev.048520 · Cited by 52

A critical step for postsynaptic F‐actin organization: Regulation of Baz/Par‐3 localization by aPKC and PTEN

Ramachandran, P., Barría, R., Ashley, J., & Budnik, V. (2009) · Developmental Neurobiology · doi:10.1002/dneu.20728 · Cited by 45

Drosophila Rho-kinase (DRok) is required for tissue morphogenesis in diverse compartments of the egg chamber during oogenesis

Verdier, V., Johndrow, J. E., Betson, M., Chen, G.-C., Hughes, D. A., Parkhurst, S. M., & Settleman, J. E. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.05.016 · Cited by 16

Collective cell migration requires suppression of actomyosin at cell–cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6

Hidalgo-Carcedo, C., Hooper, S., Chaudhry, S. I., Williamson, P., Harrington, K., Leitinger, B., & Sahai, E. (2011) · Nature Cell Biology · doi:10.1038/ncb2133 · Cited by 366

The Apical Polarity Protein Network in Drosophila Epithelial Cells: Regulation of Polarity, Junctions, Morphogenesis, Cell Growth, and Survival

Tepass, U. (2012) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154033 · Cited by 334

Apical–basal polarity and the control of epithelial form and function

Buckley, C. E., & St Johnston, D. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00465-y · Cited by 295

Recapitulation of morphogenetic cell shape changes enables wound re-epithelialisation

Razzell, W., Wood, W., & Martin, P. (2014) · Development · doi:10.1242/dev.107045 · Cited by 82