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Potently cytotoxic natural killer cells initially emerge from erythro‐myeloid progenitors during mammalian development
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“On the contrary, EMPs obtained from the YS and fetal liver at different stages behave the same in clonogenic assays in vitro. 32 , 247”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [247]
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Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
Gomez Perdiguero, E., Klapproth, K., Schulz, C., Busch, K., Azzoni, E., Crozet, L., Garner, H., Trouillet, C., de Bruijn, M. F., Geissmann, F., et al. (2015) · Nature · doi:10.1038/nature13989 · Cited by 2,339 · cited 3×
“EMP seed the fetal liver and differentiate into definitive erythroid, megakaryocyte and multiple myeloid lineages (Gomez Perdiguero et al., 2015; Lux et al., 2008; McGrath et al., 2015a).”
BackgroundMethodHoeffel, G., Chen, J., Lavin, Y., Low, D., Almeida, F. F., See, P., Beaudin, A. E., Lum, J., Low, I., Forsberg, E. C., et al. (2015) · Immunity · doi:10.1016/j.immuni.2015.03.011 · Cited by 1,135 · cited 1×
“To test this hypothesis, we utilized the tamoxifen-inducible Csf1rMerCreMerRosa26YFP mouse model, which has been used to lineage trace the macrophage potential of EMP (Gomez Perdiguero et al., 2015; Hoeffel et al., 2015).”
MethodInduced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer
Hermanson, D. L., Bendzick, L., Pribyl, L., McCullar, V., Vogel, R. I., Miller, J. S., Geller, M. A., & Kaufman, D. S. (2016) · Stem Cells · doi:10.1002/stem.2230 · Cited by 242
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Mast cell ontogeny: From fetal development to life‐long health and disease
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Metadata
- Authors
- Dege, C., Fegan, K. H., Creamer, J. P., Berrien-Elliott, M. M., Luff, S. A., Kim, D., Wagner, J. A., Kingsley, P. D., McGrath, K. E., Fehniger, T. A., Palis, J., & Sturgeon, C. M.
- Venue
- Developmental Cell
- Publisher
- Elsevier BV
- Published
- 2020-04
- Volume
- 53
- Issue
- 2
- Pages
- 229-239.e7
- ISSN
- 1534-5807
- PMC
- PMC7185477
- Cited by
- 93
- References
- 3
- Language
- en
- Licence
- Funders
- National Heart, Lung, and Blood Institute (HL007088-41)
- American Cancer Society (IRG-58-010-59-2)
- National Center for Advancing Translational Sciences (UL1TR002345)
- National Institutes of Health (DK09361)
- Center of Regenerative Medicine, Washington University in St. Louis
- University of Rochester
- Center for Cellular Imaging, Washington University
- American Society of Hematology
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- Dege, C., Fegan, K. H., Creamer, J. P., Berrien-Elliott, M. M., Luff, S. A., Kim, D., Wagner, J. A., Kingsley, P. D., McGrath, K. E., Fehniger, T. A., Palis, J., & Sturgeon, C. M. (2020). Potently cytotoxic natural killer cells initially emerge from erythro‐myeloid progenitors during mammalian development. Developmental Cell. https://doi.org/10.1016/j.devcel.2020.02.016