Outcome in AN adult patients: A 13-year follow-up in 484 patients
Abstract
Background To study the long-term prognosis of anorexia nervosa (AN), 484 adult AN patients were followed on a mean duration of 13 years.Results The mortality rate was 1.2%. Eight factors were linked to the lack of recovery at 2 years: low BMI at discharge, low energy and fat intakes, high drive for excessive exercising, high score for perfectionism, for interpersonal distrust and for anxiety, use of tube-feeding and adhesion to treatment (P<0.02). Four factors explained the risk of the binge/purging form at 2 years: having had binge-eating disorder and overweight before AN, having had purging episodes within the first 2 years of AN; having had very high energy intakes through meals and being not treated by tube-feeding. During the 13-year follow-up, very few binge/purging patients turned out to have the restrictive form. Two main factors explained 67% of the variance of menses recovery: having a BMI>18.5 kg/m(2); and having no physical hyperactivity. The recovery rate increased with the elapsing of relapse-free time (P=0.02). After a 13.5-year follow-up, 292 out of the 484 patients were recovered (60.3%), 25.8% had a relatively good outcome, 6.4% a bad outcome and 6.4% a severe outcome. Very few factors were identified as predictors of a good outcome (binge-eating/purging subtype, personality disorder).
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Achieving a healthy weight in intensive treatment is the strongest predictor of recovery from anorexia nervosa.
“achieving a healthy weight in intensive treatment is the strongest predictor of recovery [14–16].”
From Terminal anorexia nervosa is a dangerous term: it cannot, and should not, be defined (2022) · cites this paper as [15]
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Terminal anorexia nervosa is a dangerous term: it cannot, and should not, be defined
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- Authors
- Rigaud, D., Pennacchio, H., Bizeul, C., Reveillard, V., & Vergès, B.
- Affiliations
- CHU Dijon Bourgogne (FR)
- Corresponding author
- Rigaud, D.
- ORCID
- Vergès, B.
- Venue
- Diabetes & Metabolism
- Publisher
- Elsevier BV
- Published
- 2011-09
- Volume
- 37
- Issue
- 4
- Pages
- 305-311
- ISSN
- 1262-3636 (ISSN-L)
- OpenAlex
- W2067383854
- Cited by
- 98
- References
- 38
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 7 · 2021: 2 · 2020: 13 · 2019: 9 · 2018: 4 · 2017: 11 · 2016: 8 · 2015: 9 · 2014: 7 · 2013: 12 · 2012: 5
- FWCI
- 8.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diabetes & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- Ministère de la Santé
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- anorexia nervosa, long-term prognosis, relapse, binge eating disorder, purging, restrictive anorexia nervosa, mortality, body mass index, perfectionism, interpersonal distrust, anxiety, physical activity, tube feeding, medication adherence, menstrual recovery, personality disorders, prognostic factors, adult patients, follow-up study, eating disorders, bulimia nervosa
- MeSH terms
- Adult, Anorexia Nervosa, Anxiety, Depression, Female, Follow-Up Studies, Humans, Male, Menstruation Disturbances, Prognosis, Surveys and Questionnaires, Recurrence, Risk Factors, Body Mass Index, Treatment Outcome
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