Cited by 81Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease PreventionDiabetes, Cardiovascular Risks, and Lipoproteins

Endothelial dysfunction: causes and consequences in patients with diabetes mellitus.

Avogaro, Angelo, Kreutzenberg, Saula Vigili de, Fadini, GianPaolo·2008·Diabetes Research and Clinical Practice

Abstract

Vascular endothelium plays a major role in maintaining cardiovascular homeostasis. Nitric oxide is the most powerful vasodilating compound. Diabetes disrupts endothelial integrity through an increased oxidative stress. Recent evidence indicates that there is a strong interaction between diabetes, the secretory proteins of adipocytes, called adipokines, and endothelium. Endothelial dysfunction may precede the development of overt DM, and a prolonged and repeated exposure to postprandial hyperglycemia may play an important role in the development of atherosclerosis, even in those who have normal fasting plasma glucose levels.

Integrity signals

Registry

Crossref · 10.1016/j.diabres.2008.09.021

Cites

55 of 55 references verified0 citation errors · 0 not checkable

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Authors
Avogaro, A., Kreutzenberg, S. V. D., & Fadini, G.
Affiliations
University of Padua (IT)
Venue
Diabetes Research and Clinical Practice
Publisher
Elsevier BV
Published
2008-12
Volume
82
Pages
S94-S101
ISSN
0168-8227 (ISSN-L)
OpenAlex
W1992504098
Cited by
81
References
54
Citations by year
2025: 1 · 2024: 7 · 2023: 1 · 2022: 2 · 2021: 5 · 2020: 7 · 2019: 2 · 2018: 5 · 2017: 2 · 2016: 6 · 2015: 8 · 2014: 9 · 2013: 6 · 2012: 10
FWCI
0.36
Type
journal article
Language
en
Open access
closed
Locations
  • Diabetes Research and Clinical Practice (publishedVersion)
  • PubMed (publishedVersion)
  • Padua Research Archive (University of Padova) (submittedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
endothelial dysfunction, diabetes mellitus, nitric oxide, oxidative stress, adipokines, adipocytes, postprandial hyperglycemia, atherosclerosis, cardiovascular homeostasis
MeSH terms
Diabetes Mellitus, Endothelium, Vascular, Humans, Nitric Oxide, Oxidative Stress, Adipokines

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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