The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Peptide Antimicrobial Agents
Open accessAbstract
SUMMARY: Antimicrobial host defense peptides are produced by all complex organisms as well as some microbes and have diverse and complex antimicrobial activities. Collectively these peptides demonstrate a broad range of antiviral and antibacterial activities and modes of action, and it is important to distinguish between direct microbicidal and indirect activities against such pathogens. The structural requirements of peptides for antiviral and antibacterial activities are evaluated in light of the diverse set of primary and secondary structures described for host defense peptides. Peptides with antifungal and antiparasitic activities are discussed in less detail, although the broad-spectrum activities of such peptides indicate that they are important host defense molecules. Knowledge regarding the relationship between peptide structure and function as well as their mechanism of action is being applied in the design of antimicrobial peptide variants as potential novel therapeutic agents.
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Cites
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?
Brogden, K. A. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1098 · Cited by 5,829
Defensins: antimicrobial peptides of innate immunity
Ganz, T. (2003) · Nature Reviews Immunology · doi:10.1038/nri1180 · Cited by 3,066
Bacteriocins: Developing innate immunity for food
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Anti-microbial peptides: from invertebrates to vertebrates
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Cathelicidins, multifunctional peptides of the innate immunity
Zanetti, M. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0403147 · Cited by 988
Cationic peptides: effectors in innate immunity and novel antimicrobials
Hancock, R. E. (2001) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(01)00092-5 · Cited by 978
Self-citationYang, D., Biragyn, A., Hoover, D. M., Lubkowski, J., & Oppenheim, J. J. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104603 · Cited by 572
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Deficiency of antibacterial peptides in patients with morbus Kostmann: an observation study
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Histatins: Antimicrobial peptides with therapeutic potential
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“variant of histatins, which are naturally occurring cationic peptides in saliva (124).”
Background
Cited by
Endosomal escape pathways for delivery of biologicals
Varkouhi, A. K., Scholte, M., Storm, G., & Haisma, H. J. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.11.004 · Cited by 1,561
Antimicrobial host defence peptides: functions and clinical potential
Mookherjee, N., Anderson, M. A., Haagsman, H. P., & Davidson, D. J. (2020) · Nature Reviews Drug Discovery · doi:10.1038/s41573-019-0058-8 · Cited by 1,502
CAMP: a useful resource for research on antimicrobial peptides.
Thomas, S., Karnik, S., Barai, R. S., Jayaraman, V. K., & Idicula-Thomas, S. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkp1021 · Cited by 462
Mehbub, M., Lei, J., Franco, C., & Zhang, W. (2014) · Marine Drugs · doi:10.3390/md12084539 · Cited by 417
Quaternary ammonium salts and their antimicrobial potential: targets or nonspecific interactions
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Metadata
- Authors
- Jenssen, H., Hamill, P., & Hancock, R. E. W.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2006-07
- Volume
- 19
- Issue
- 3
- Pages
- 491-511
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- OpenAlex
- W2159861471
- Cited by
- 2,518
- References
- 10
- FWCI
- 62.43
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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