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Cited by 2,518

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Peptide Antimicrobial Agents

Open access
Jenssen, Håvard, Hamill, Pamela, Hancock, Robert E. W.·2006·Clinical Microbiology Reviews

Abstract

SUMMARY: Antimicrobial host defense peptides are produced by all complex organisms as well as some microbes and have diverse and complex antimicrobial activities. Collectively these peptides demonstrate a broad range of antiviral and antibacterial activities and modes of action, and it is important to distinguish between direct microbicidal and indirect activities against such pathogens. The structural requirements of peptides for antiviral and antibacterial activities are evaluated in light of the diverse set of primary and secondary structures described for host defense peptides. Peptides with antifungal and antiparasitic activities are discussed in less detail, although the broad-spectrum activities of such peptides indicate that they are important host defense molecules. Knowledge regarding the relationship between peptide structure and function as well as their mechanism of action is being applied in the design of antimicrobial peptide variants as potential novel therapeutic agents.

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Crossref · 10.1128/cmr.00056-05

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Metadata

Authors
Jenssen, H., Hamill, P., & Hancock, R. E. W.
Venue
Clinical Microbiology Reviews
Published
2006-07
Volume
19
Issue
3
Pages
491-511
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
OpenAlex
W2159861471
Cited by
2,518
References
10
FWCI
62.43
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Peptide Antimicrobial Agents. https://app.cochat.ai/papers/10.1128/cmr.00056-05
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Jenssen, H., Hamill, P., & Hancock, R. E. W. (2006). Peptide Antimicrobial Agents. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.00056-05

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.