The DOI matches its Crossref record; 66 of the 68 references it cites were found in a registry or an index.
Hypoglycemia in Type 1 Diabetes Mellitus
Open accessAbstract
Iatrogenic hypoglycemia, typically the result of the interplay of therapeutic hyperinsulinemia and compromised defenses resulting in hypoglycemia-associated autonomic failure (HAAF) in diabetes, is a problem for people with type 1 diabetes mellitus (T1DM). It causes recurrent morbidity is sometimes fatal, leads to recurrent hypoglycemia, and precludes euglycemia over a lifetime of T1DM. Risk factors include those that result in relative or absolute insulin excess and those indicative of HAAF in diabetes. Elimination of hypoglycemia from the lives of people with T1DM will likely be accomplished by new treatment methods that provide plasma glucose-regulated insulin replacement or secretion.
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“People with type 1 diabetes, particularly those with concomitant chronic kidney disease, are at higher risk of hypoglycemia, which should be avoided by careful insulin and carbohydrate matching (129).”
From The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (2021) · cites this paper as [129]
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Cites
(1993) · New England Journal of Medicine · doi:10.1056/nejm199309303291401 · Cited by 24,667
Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes
(2005) · New England Journal of Medicine · doi:10.1056/nejmoa052187 · Cited by 5,138
Standards of Medical Care in Diabetes—2009
American Diabetes Association (2009) · Diabetes Care · doi:10.2337/dc09-s013 · Cited by 2,167
Continuous glucose monitoring and intensive treatment of type 1 diabetes
(2008) · New England Journal of Medicine · doi:10.1056/nejmoa0805017 · Cited by 1,559
Cryer, P. E., Axelrod, L., Grossman, A. B., Heller, S. R., Montori, V. M., Seaquist, E. R., & Service, F. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1410 · Cited by 1,277 · cited 1×
“The vast majority of episodes of hypoglycemia in people with T1DM are iatrogenic, but those individuals can suffer from hypoglycemia caused by mechanisms other than insulin treatment [58].”
BackgroundSelf-citationCryer, P. E., Davis, S. N., & Shamoon, H. (2003) · Diabetes Care · doi:10.2337/diacare.26.6.1902 · Cited by 1,160 · cited 5×
“Minimizing the risk of hypoglycemia in T1DM involves the practice of hypoglycemia risk factor reduction [1,2,34,36,37].”
BackgroundInfluentialSelf-citationDefining and Reporting Hypoglycemia in Diabetes
American Diabetes Association Workgroup on Hypoglycemia (2005) · Diabetes Care · doi:10.2337/diacare.28.5.1245 · Cited by 1,146
Skyler, J. S., Bergenstal, R., Bonow, R. O., Buse, J., Deedwania, P., Gale, E. A. M., Howard, B. V., Kirkman, M. S., Kosiborod, M., Reaven, P., et al. (2009) · Diabetes Care · doi:10.2337/dc08-9026 · Cited by 881
Risk of hypoglycaemia in types 1 and 2 diabetes: Effects of treatment modalities and their duration
UK Hypoglycaemia Study Group (2007) · Diabetologia · doi:10.1007/s00125-007-0599-y · Cited by 825
Epidemiology of severe hypoglycemia in the diabetes control and complications trial
(1991) · The American Journal of Medicine · doi:10.1016/0002-9343(91)80085-z · Cited by 807
Flagged first, then by citations
2 of the 68 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Hopkins, 2008, Routine structured education reduces HbA1C and hypoglycemia and improves psychological health in patients with type 1 diabetes mellitus [abstract], Diabetes, 57, A37
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Items 201–204 of 204
Bader, S., Ashfaq, A., Mussa, B. M., Alawadi, F., Bhamidimarri, P. M., Al-Abadla, Z., & Abusnana, S. (2026) · Acta Neurologica Scandinavica · doi:10.1155/ane/6400429
Glucose-Responsive Nanomedicine in Diabetes Therapy: Emerging Advances and Clinical Prospects
Alsaei, A., Binrajab, A., Alsaei, S., Rahimi, F., Zarwi, A., Zarwi, H. N., AlAnsari, R., & Deen, G. R. (2026) · Journal of Functional Biomaterials · doi:10.3390/jfb17090424
Ajie, M., Ali, N., Hendriksz, M. S., Divilly, P., Rietveld, M. J., Abbink, E. J., Choudhary, P., Brøsen, J. M. B., Pedersen‐Bjergaard, U., McCrimmon, R. J., et al. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.71321
The Role Of Authoritative Parenting In Type 1 Diabetes Adolescent Outcomes
Radcliff, Z. (2014) · VCU Scholars Compass (Virginia Commonwealth University) · doi:10.25772/xxbh-ce82
Metadata
- Authors
- Cryer, P. E.
- Affiliations
- Barnes-Jewish Hospital (US)
- Corresponding author
- Cryer, Philip E.
- Venue
- Endocrinology and Metabolism Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2010-09
- Volume
- 39
- Issue
- 3
- Pages
- 641-654
- ISSN
- 0889-8529 (ISSN-L)
- PMC
- PMC2923455
- OpenAlex
- W2009090185
- Cited by
- 205
- References
- 68
- Citations by year
- 2026: 16 · 2025: 20 · 2024: 11 · 2023: 12 · 2022: 12 · 2021: 21 · 2020: 14 · 2019: 13 · 2018: 12 · 2017: 11 · 2016: 9 · 2015: 10 · 2014: 9 · 2013: 16 · 2012: 11
- FWCI
- 1.50
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Endocrinology and Metabolism Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5p60dk020579-35, UL1TR000448)
- National Institute of Diabetes and Digestive and Kidney Diseases (R37DK027085, P60-DK20579, R37-DK27085, T32 DK07120, P60-DK-020579, P30DK020579, T32DK007120)
- National Center for Research Resources (UL1-RR-24992, M01-RR00036, UL1RR024992, M01RR000036)
- NIH Clinical Center
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- hypoglycemia, type 1 diabetes, hypoglycemia-associated autonomic failure, iatrogenic hypoglycemia, hyperinsulinemia, insulin excess, hypoglycemia risk factors, insulin secretion
- MeSH terms
- Blood Glucose, Diabetes Mellitus, Type 1, Humans, Hypoglycemia, Models, Biological, Risk Factors
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