Cited by 205Diabetes Management and ResearchDiabetes and associated disordersDiabetes Treatment and Management

The DOI matches its Crossref record; 66 of the 68 references it cites were found in a registry or an index.

Hypoglycemia in Type 1 Diabetes Mellitus

Open access

Cryer, Philip E.·2010·Endocrinology and Metabolism Clinics of North America

DOI 10.1016/j.ecl.2010.05.003PMC PMC2923455

Open this paper in CoChat — free account

Abstract

Iatrogenic hypoglycemia, typically the result of the interplay of therapeutic hyperinsulinemia and compromised defenses resulting in hypoglycemia-associated autonomic failure (HAAF) in diabetes, is a problem for people with type 1 diabetes mellitus (T1DM). It causes recurrent morbidity is sometimes fatal, leads to recurrent hypoglycemia, and precludes euglycemia over a lifetime of T1DM. Risk factors include those that result in relative or absolute insulin excess and those indicative of HAAF in diabetes. Elimination of hypoglycemia from the lives of people with T1DM will likely be accomplished by new treatment methods that provide plasma glucose-regulated insulin replacement or secretion.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.ecl.2010.05.003

Cites

66 of 66 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus
(1993) · New England Journal of Medicine · doi:10.1056/nejm199309303291401 · Cited by 24,667
Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes
(2005) · New England Journal of Medicine · doi:10.1056/nejmoa052187 · Cited by 5,138
Standards of Medical Care in Diabetes—2009
American Diabetes Association (2009) · Diabetes Care · doi:10.2337/dc09-s013 · Cited by 2,167
Continuous glucose monitoring and intensive treatment of type 1 diabetes
(2008) · New England Journal of Medicine · doi:10.1056/nejmoa0805017 · Cited by 1,559
Evaluation and Management of Adult Hypoglycemic Disorders: An Endocrine Society Clinical Practice Guideline
Cryer, P. E., Axelrod, L., Grossman, A. B., Heller, S. R., Montori, V. M., Seaquist, E. R., & Service, F. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1410 · Cited by 1,277 · cited 1×
“The vast majority of episodes of hypoglycemia in people with T1DM are iatrogenic, but those individuals can suffer from hypoglycemia caused by mechanisms other than insulin treatment [58].”
BackgroundSelf-citation
Hypoglycemia in Diabetes
Cryer, P. E., Davis, S. N., & Shamoon, H. (2003) · Diabetes Care · doi:10.2337/diacare.26.6.1902 · Cited by 1,160 · cited 5×
“Minimizing the risk of hypoglycemia in T1DM involves the practice of hypoglycemia risk factor reduction [1,2,34,36,37].”
BackgroundInfluentialSelf-citation
Defining and Reporting Hypoglycemia in Diabetes
American Diabetes Association Workgroup on Hypoglycemia (2005) · Diabetes Care · doi:10.2337/diacare.28.5.1245 · Cited by 1,146
Intensive Glycemic Control and the Prevention of Cardiovascular Events: Implications of the ACCORD, ADVANCE, and VA Diabetes Trials
Skyler, J. S., Bergenstal, R., Bonow, R. O., Buse, J., Deedwania, P., Gale, E. A. M., Howard, B. V., Kirkman, M. S., Kosiborod, M., Reaven, P., et al. (2009) · Diabetes Care · doi:10.2337/dc08-9026 · Cited by 881
Risk of hypoglycaemia in types 1 and 2 diabetes: Effects of treatment modalities and their duration
UK Hypoglycaemia Study Group (2007) · Diabetologia · doi:10.1007/s00125-007-0599-y · Cited by 825
Epidemiology of severe hypoglycemia in the diabetes control and complications trial
(1991) · The American Journal of Medicine · doi:10.1016/0002-9343(91)80085-z · Cited by 807

Flagged first, then by citations

Show all 68 references

2 of the 68 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

Hopkins, 2008, Routine structured education reduces HbA1C and hypoglycemia and improves psychological health in patients with type 1 diabetes mellitus [abstract], Diabetes, 57, A37

Sorted by citations

The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Holt, R. I. G., DeVries, J. H., Hess-Fischl, A., Hirsch, I. B., Kirkman, M. S., Klupa, T., Ludwig, B., Nørgaard, K., Pettus, J., Renard, E., et al. (2021) · Diabetes Care · doi:10.2337/dci21-0043 · Cited by 699
Threshold-based insulin-pump interruption for reduction of hypoglycemia
Bergenstal, R. M., Klonoff, D. C., Garg, S. K., Bode, B. W., Meredith, M., Slover, R. H., Ahmann, A. J., Welsh, J. B., Lee, S. W., & Kaufman, F. R. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1303576 · Cited by 652
The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Holt, R. I. G., DeVries, J. H., Fischl, A. H., Hirsch, I. B., Kirkman, M. S., Klupa, T., Ludwig, B., Nørgaard, K., Pettus, J., Renard, É., et al. (2021) · Diabetologia · doi:10.1007/s00125-021-05568-3 · Cited by 470
Severe hypoglycemia and diabetic ketoacidosis in adults with type 1 diabetes: results from the T1D Exchange clinic registry
Weinstock, R. S., Xing, D., Maahs, D. M., Michels, A., Rickels, M. R., Peters, A. L., Bergenstal, R. M., Harris, B., DuBose, S. N., Miller, K. M., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1589 · Cited by 338
Diabetes Technology Update: Use of Insulin Pumps and Continuous Glucose Monitoring in the Hospital
Umpierrez, G. E., & Klonoff, D. C. (2018) · Diabetes Care · doi:10.2337/dci18-0002 · Cited by 260
Predictive low-glucose suspend reduces hypoglycemia in adults, adolescents, and children with type 1 diabetes in an at-home randomized crossover study: results of the PROLOG trial
Forlenza, G. P., Li, Z., Buckingham, B. A., Pinsker, J. E., Cengiz, E., Wadwa, R. P., Ekhlaspour, L., Church, M. M., Weinzimer, S. A., Jost, E., et al. (2018) · Diabetes Care · doi:10.2337/dc18-0771 · Cited by 246
Type 1 diabetes mellitus: much progress, many opportunities
Powers, A. C. (2021) · Journal of Clinical Investigation · doi:10.1172/jci142242 · Cited by 172
Stress and A1c Among People with Diabetes Across the Lifespan
Hilliard, M. E., Yi‐Frazier, J. P., Hessler, D., Butler, A. M., Anderson, B. J., & Jaser, S. S. (2016) · Current Diabetes Reports · doi:10.1007/s11892-016-0761-3 · Cited by 149
Inhaled Technosphere insulin compared with injected prandial insulin in type 1 diabetes: A randomized 24-week trial
Bode, B. W., McGill, J. B., Lorber, D. L., Gross, J. L., Chang, P.-C., Bregman, D. B., & for the Affinity 1 Study Group (2015) · Diabetes Care · doi:10.2337/dc15-0075 · Cited by 114
Why should people with type 1 diabetes exercise regularly?
Codella, R., Terruzzi, I., & Luzi, L. (2017) · Acta Diabetologica · doi:10.1007/s00592-017-0978-x · Cited by 108
Hypoglycemia
Morales, J., & Schneider, D. (2014) · The American Journal of Medicine · doi:10.1016/j.amjmed.2014.07.004 · Cited by 106
ISPAD Clinical Practice Consensus Guidelines 2022: Assessment and management of hypoglycemia in children and adolescents with diabetes
Abraham, M. B., Karges, B., Dovč, K., Naranjo, D. M., Arbeláez, A. M., Mbogo, J., Javelikar, G., Jones, T. W., & Mahmud, F. H. (2022) · Pediatric Diabetes · doi:10.1111/pedi.13443 · Cited by 112
Medical devices, smart drug delivery, wearables and technology for the treatment of Diabetes Mellitus
Domingo‐Lopez, D. A., Lattanzi, G., Schreiber, L. H. J., Wallace, E. J., Wylie, R., O’Sullivan, J., Dolan, E. B., & Duffy, G. P. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114280 · Cited by 109
Hybrid closed‐loop glucose control with faster insulin aspart compared with standard insulin aspart in adults with type 1 diabetes: A double‐blind, multicentre, multinational, randomized, crossover study
Boughton, C. K., Hartnell, S., Thabit, H., Poettler, T., Herzig, D., Wilinska, M. E., Ashcroft, N. L., Sibayan, J., Cohen, N., Calhoun, P. M., et al. (2021) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14355 · Cited by 96
Pathway-selective Insulin Resistance and Metabolic Disease: The Importance of Nutrient Flux
Otero, Y. F., Stafford, J. M., & McGuinness, O. P. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.r114.576355 · Cited by 97
Management of Type 1 Diabetes in Older Adults
Dhaliwal, R., & Weinstock, R. S. (2014) · Diabetes Spectrum · doi:10.2337/diaspect.27.1.9 · Cited by 87
Closed-Loop Insulin Delivery for Adults with Type 1 Diabetes Undertaking High-Intensity Interval Exercise Versus Moderate-Intensity Exercise: A Randomized, Crossover Study
Jayawardene, D., McAuley, S. A., Horsburgh, J. C., Gerche, A. L., Jenkins, A. J., Ward, G. M., MacIsaac, R. J., Roberts, T. J., Grosman, B., Kurtz, N., et al. (2017) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2016.0461 · Cited by 82
Management of Diabetes in the Elderly
Bansal, N., Dhaliwal, R., & Weinstock, R. S. (2014) · Medical Clinics of North America · doi:10.1016/j.mcna.2014.11.008 · Cited by 82
Insulin Degludec/Insulin Aspart Administered Once Daily at Any Meal, With Insulin Aspart at Other Meals Versus a Standard Basal-Bolus Regimen in Patients With Type 1 Diabetes
Hirsch, I. B., Bode, B. W., Courrèges, J. P., Dykiel, P., Franek, E., Hermansen, K., King, A. B., Mersebach, H., & Davies, M. J. (2012) · Diabetes Care · doi:10.2337/dc11-2503 · Cited by 77
Impact of Ramadan Diurnal Intermittent Fasting on Hypoglycemic Events in Patients With Type 2 Diabetes: A Systematic Review of Randomized Controlled Trials and Observational Studies
Abdelrahim, D. N., Faris, M. E., Hassanein, M. M., Shakir, A. Z., Yusuf, A. M., Almeneessier, A. S., & BaHammam, A. S. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.624423 · Cited by 67
Glucagon-like peptide 1 analogues as adjunctive therapy for patients with type 1 diabetes: An updated systematic review and meta-analysis
Park, J., Ntelis, S., Yunasan, E., Downton, K. D., Yip, T. C.-F., Munir, K. M., & Haq, N. (2023) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgad471 · Cited by 69
Impact of CGM on the management of hypoglycemia problems: overview and secondary analysis of the HypoDE study
Hermanns, N., Heinemann, L., Freckmann, G., Waldenmaier, D., & Ehrmann, D. (2019) · Journal of Diabetes Science and Technology · doi:10.1177/1932296819831695 · Cited by 66
Prospective study evaluating the use of nasal glucagon for the treatment of moderate to severe hypoglycaemia in adults with type 1 diabetes in a real‐world setting
Seaquist, E. R., Dulude, H., Zhang, X. M., RABASA-LHORET, R. P. R., Tsoukas, G. M., Conway, J. R., Weisnagel, S. J., Gerety, G., Woo, V. C., Zhang, S., et al. (2018) · Diabetes Obesity and Metabolism · doi:10.1111/dom.13278 · Cited by 54
Hypoglycemia in Patients with Type 1 Diabetes: Epidemiology, Pathogenesis, and Prevention
Awoniyi, O., Rehman, R., & Dagogo-Jack, S. E. (2013) · Current Diabetes Reports · doi:10.1007/s11892-013-0411-y · Cited by 55
Inhaled Technosphere Insulin Compared With Injected Prandial Insulin in Type 1D iabetes: A Randomized 24-Week Trial
Einstein, A. (2015) · Cited by 47
Nationwide reduction in the frequency of severe hypoglycemia by half
The Danish Society for Diabetes in Childhood and Adolescence, Fredheim, S., Johansen, A., Thorsen, S. U., Kremke, B., Nielsen, L. B., Olsen, B. S., Lyngsøe, L., Sildorf, S. M., Pipper, C. B., et al. (2014) · Acta Diabetologica · doi:10.1007/s00592-014-0697-5 · Cited by 46
Recombinant Human Insulins – Clinical Efficacy and Safety in Diabetes Therapy
Landgraf, W., & SANDOW, J. (2016) · touchREVIEWS in Endocrinology · doi:10.17925/ee.2016.12.01.12 · Cited by 46
Amelioration of Hypoglycemia Via Somatostatin Receptor Type 2 Antagonism in Recurrently Hypoglycemic Diabetic Rats
Yue, J. T. Y., Riddell, M. C., Burdett, E., Coy, D. H., Efendic, S., & Vranic, M. (2013) · Diabetes · doi:10.2337/db12-1523 · Cited by 45
Counter‐regulatory hormone responses to hypoglycaemia in people with type 1 diabetes after 4 weeks of treatment with liraglutide adjunct to insulin: a randomized, placebo‐controlled, double‐blind, crossover trial
Pieber, T. R., Deller, S., Korsatko, S., Jensen, L., Christiansen, E., Madsen, J. C., & Heller, S. R. (2015) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12473 · Cited by 46
Practical Considerations on the Use of Continuous Glucose Monitoring in Pediatrics and Older Adults and Nonadjunctive Use
Forlenza, G. P., Argento, N. B., & Laffel, L. M. (2017) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2017.0034 · Cited by 47
Efficacy and safety of mini-dose glucagon for treatment of nonsevere hypoglycemia in adults with type 1 diabetes
Haymond, M. W., DuBose, S. N., Rickels, M. R., Wolpert, H., Shah, V. N., Sherr, J. L., Weinstock, R. S., Agarwal, S., Verdejo, A. S., Cummins, M. J., et al. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-00591 · Cited by 42
Suprachiasmatic nucleus-mediated glucose entry into the arcuate nucleus determines the daily rhythm in blood glycemia
Rodríguez-Cortés, B., Hurtado‐Alvarado, G., Martínez-Gómez, R., Mercado, L. L., Prager‐Khoutorsky, M., & Buijs, R. M. (2022) · Current Biology · doi:10.1016/j.cub.2021.12.039 · Cited by 44
Acute and Chronic Adverse Outcomes of Type 1 Diabetes
LONGENDYKE, R. L., Grundman, J., & Majidi, S. (2023) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2023.09.004 · Cited by 49
Hyperglycemia / hypoglycemia-induced mitochondrial dysfunction and cerebral ischemic damage in diabetics
Rehni, A. K., Nautiyal, N., Pérez‐Pinzón, M. A., & Dave, K. R. (2014) · Metabolic Brain Disease · doi:10.1007/s11011-014-9538-z · Cited by 43
Defining High Glycemic Variability in Type 1 Diabetes: Comparison of Multiple Indexes to Identify Patients at Risk of Hypoglycemia
Gómez, A. M., Henao, D. C., Madero, A. I., Taboada, L. B., Cruz, V., Gómez, M. A. R., Rondón, M., Múñoz, Ó., Maira, G., & Vargas, F. M. L. (2019) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2019.0075 · Cited by 41
Overcoming barriers in clinical islet transplantation: Current limitations and future prospects
Chhabra, P., Sutherland, D. E. R., & Brayman, K. L. (2013) · Current Problems in Surgery · doi:10.1067/j.cpsurg.2013.10.002 · Cited by 40
Hindbrain Estrogen Receptor Regulation of Ventromedial Hypothalamic Glycogen Metabolism and Glucoregulatory Transmitter Expression in the Hypoglycemic Female Rat
Napit, P. R., Ali, M. H., Shakya, M., Mandal, S. K., Bheemanapally, K., Mahmood, A. S. M. H., Ibrahim, M. M. H., & Briski, K. P. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.05.007 · Cited by 35
Management of type 1 diabetes in the hospital setting
Mendez, C. E., & Umpierrez, G. E. (2017) · Current Diabetes Reports · doi:10.1007/s11892-017-0919-7 · Cited by 34
Sex differences in forebrain estrogen receptor regulation of hypoglycemic patterns of counter-regulatory hormone secretion and ventromedial hypothalamic nucleus glucoregulatory neurotransmitter and astrocyte glycogen metabolic enzyme expression
Mahmood, A. S. M. H., Uddin, M. M., Ibrahim, M. M. H., Mandal, S. K., Alhamami, H. N., & Briski, K. P. (2018) · Neuropeptides · doi:10.1016/j.npep.2018.10.003 · Cited by 32
Effects of acute versus recurrent insulin-induced hypoglycemia on ventromedial hypothalamic nucleus metabolic-sensory neuron AMPK activity: Impact of alpha1-adrenergic receptor signaling
Briski, K. P., Mandal, S. K., Bheemanapally, K., & Ibrahim, M. M. H. (2020) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2020.01.013 · Cited by 32
Nocturnal Continuous Glucose and Sleep Stage Data in Adults with Type 1 Diabetes in Real-World Conditions
Feupe, S. F., Frias, P. F., Mednick, S. C., McDevitt, E. A., & Heintzman, N. D. (2013) · Journal of Diabetes Science and Technology · doi:10.1177/193229681300700525 · Cited by 33
The Rate of Fall of Blood Glucose Determines the Necessity of Forebrain-Projecting Catecholaminergic Neurons for Male Rat Sympathoadrenal Responses
Jokiaho, A. J., Donovan, C. M., & Watts, A. G. (2014) · Diabetes · doi:10.2337/db13-1753 · Cited by 31
Effect of once‐weekly semaglutide on the counterregulatory response to hypoglycaemia in people with type 2 diabetes: A randomized, placebo‐controlled, double‐blind, crossover trial
Korsatko, S., Jensen, L., Brunner, M., Sach‐Friedl, S., Tarp, M. D., Holst, A. G., Heller, S. R., & Pieber, T. R. (2018) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.13422 · Cited by 29
Impact of C-Peptide Status on the Response of Glucagon and Endogenous Glucose Production to Induced Hypoglycemia in T1DM
Zenz, S., Mader, J. K., Regittnig, W., Brunner, M., Korsatko, S., Boulgaropoulos, B., Magnes, C., Raml, R., Narath, S. H., Eller, P., et al. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-01836 · Cited by 29
Hindbrain estrogen receptor regulation of ventromedial hypothalamic glycogen metabolism and glucoregulatory transmitter expression in the hypoglycemic male rat
Ali, M. H., Napit, P. R., Mahmood, A. S. M. H., Bheemanapally, K., Alhamami, H. N., Uddin, M. M., Mandal, S. K., Ibrahim, M. M. H., & Briski, K. P. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.03.053 · Cited by 27
Advances in Predictive, Preventive and Personalised Medicine
Karabulut, S. (2012) · Cited by 26
Has Technology Improved Diabetes Management in Relation to Age, Gender, and Ethnicity?
Eiland, L. A., Thangavelu, T., & Drincic, A. (2019) · Current Diabetes Reports · doi:10.1007/s11892-019-1231-5 · Cited by 26
The impact of islet mass, number of transplants, and time between transplants on graft function in a national islet transplant program
Forbes, S., Flatt, A. J., Bennett, D., Crookston, R. M., Pimkova, M., Birtles, L., Pernet, A., Wood, R., Burling, K., Barker, P., et al. (2021) · American Journal of Transplantation · doi:10.1111/ajt.16785 · Cited by 24
Experience of hypoglycaemia and strategies used for its management by community-dwelling adults with diabetes mellitus: a systematic review
Tan, P., Chen, H., Taylor, B. J., & Hegney, D. G. (2012) · International Journal of Evidence-Based Healthcare · doi:10.1111/j.1744-1609.2012.00276.x · Cited by 25
A real-time continuous glucose monitoring-based algorithm to trigger hypotreatments to prevent/mitigate hypoglycemic events
Camerlingo, N., Vettoretti, M., Del Favero, S., Cappon, G., Sparacino, G., & Facchinetti, A. (2019) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2019.0139 · Cited by 22
Role of hindbrain adenosine 5′-monophosphate-activated protein kinase (AMPK) in hypothalamic AMPK and metabolic neuropeptide adaptation to recurring insulin-induced hypoglycemia in the male rat
Mandal, S. K., Shrestha, P. K., Alenazi, F., Shakya, M., Alhamami, H. N., & Briski, K. P. (2017) · Neuropeptides · doi:10.1016/j.npep.2017.08.001 · Cited by 21
Use of a Smartphone Application to Reduce Hypoglycemia in Type 1 Diabetes: A Pilot Study
Feuerstein-Simon, C. B., Bzdick, S., Padmanabhuni, A., Bains, P., Roe, C. A., & Weinstock, R. S. (2018) · Journal of Diabetes Science and Technology · doi:10.1177/1932296817749859 · Cited by 20
Challenges in Modelling Hypoglycaemia-Associated Autonomic Failure: A Review of Human and Animal Studies
Senthilkumaran, M., Zhou, X.-F., & Bobrovskaya, L. (2016) · International Journal of Endocrinology · doi:10.1155/2016/9801640 · Cited by 19
Impact of Disease Duration on the Effects of Pramlintide in Type 1 Diabetes: A Post Hoc Analysis of Three Clinical Trials
Herrmann, K., Brunell, S. C., Li, Y., Zhou, M., & Maggs, D. G. (2016) · Advances in Therapy · doi:10.1007/s12325-016-0326-5 · Cited by 20
The Effects of Insulin-Induced Hypoglycaemia on Tyrosine Hydroxylase Phosphorylation in Rat Brain and Adrenal Gland
Senthilkumaran, M., Johnson, M., & Bobrovskaya, L. (2016) · Neurochemical Research · doi:10.1007/s11064-016-1875-3 · Cited by 19
Making Insulin Accessible: Does Inhaled Insulin Fill an Unmet Need?
McGill, J. B., Ahn, D. T., Edelman, S. V., Kilpatrick, C. R., & Cavaiola, T. S. (2016) · Advances in Therapy · doi:10.1007/s12325-016-0370-1 · Cited by 18
Pathophysiology and management of hypoglycemia in diabetes
RANGEL, E. S., Deajon-Jackson, J. D., & Hwang, J. J. (2022) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.14904 · Cited by 19
Current therapeutic approaches in the management of hyperglycemia in chronic renal disease
Garla, V. V., Yanes-Cardozo, L. L., & Lien, L. F. (2017) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-017-9416-1 · Cited by 17
Potential role of hypothalamic microRNAs in regulation of FOS and FTO expression in response to hypoglycemia
Mussa, B. M., Taneera, J., Mohammed, A. K., Srivastava, A., Mukhopadhyay, D., & Sulaiman, N. D. (2019) · The Journal of Physiological Sciences · doi:10.1007/s12576-019-00718-0 · Cited by 17
Continuous Glucose Monitoring as a Matter of Justice
Kraaijeveld, S. R. (2020) · HEC Forum · doi:10.1007/s10730-020-09413-9 · Cited by 19
Hypoglycemia-induced alterations in hippocampal intrinsic rhythms: Decreased inhibition, increased excitation, seizures and spreading depression
Florez, C. M., Lukankin, V., Sugumar, S., McGinn, R. J., Zhang, Z. J., Zhang, L., & Carlen, P. L. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.06.005 · Cited by 17
Assessing fear of hypoglycemia among adults with type 1 diabetes – psychometric properties of the Norwegian version of the Hypoglycemia Fear Survey II questionnaire
Graue, M., Iversen, M. M., Wentzel‐Larsen, T., Rokne, B., & Haugstvedt, A. (2013) · Norsk Epidemiologi · doi:10.5324/nje.v23i1.1605 · Cited by 17
SGLT2 Inhibition Increases Fasting Glucagon but Does Not Restore the Counterregulatory Hormone Response to Hypoglycemia in Participants With Type 1 Diabetes
BOEDER, S. C., Gregory, J. M., Giovannetti, E. R., & Pettus, J. (2021) · Diabetes · doi:10.2337/db21-0769 · Cited by 16
Comparison between a tubeless, on-body automated insulin delivery system and a tubeless, on-body sensor-augmented pump in type 1 diabetes: a multicentre randomised controlled trial
Kim, J. Y., Jin, S.-M., Kang, E. S., Kwak, S. H., Yang, Y., Yoo, J. H., Bae, J. H., Moon, J. S., Jung, C. H., Bae, J. C., et al. (2024) · Diabetologia · doi:10.1007/s00125-024-06155-y · Cited by 17
Childhood diabetes and sleep
Monzon, A. D., Patton, S. R., & Koren, D. (2021) · Pediatric Pulmonology · doi:10.1002/ppul.25651 · Cited by 17
Glucose-sensing and glucose-driven “organic engine” with co-immobilized enzyme membrane toward autonomous drug release systems for diabetes
Munkhjargal, M., Matsuura, Y., Hatayama, K., Miyajima, K., Arakawa, T., Kudo, H., & Mitsubayashi, K. (2013) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2013.07.080 · Cited by 16
Cost-effectiveness of switching to insulin degludec from other basal insulins in real-world clinical practice in Italy
Haldrup, S., Lapolla, A., Gundgaard, J., & Wolden, M. L. (2019) · Journal of Medical Economics · doi:10.1080/13696998.2019.1669613 · Cited by 16
Norepinephrine Regulation of Ventromedial Hypothalamic Nucleus Astrocyte Glycogen Metabolism
Briski, K. P., Ibrahim, M. M. H., Mahmood, A. S. M. H., & Alshamrani, A. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22020759 · Cited by 15
Endoplasmic reticulum stress in diabetes: New insights of clinical relevance
Balasubramanyam, M., Lenin, R. R., & Monickaraj, F. (2010) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-010-0022-1 · Cited by 15
The role of the new basal insulin analogs in addressing unmet clinical needs in people with type 1 and type 2 diabetes
Lajara, R., Cengiz, E., & Tanenberg, R. J. (2017) · Current Medical Research and Opinion · doi:10.1080/03007995.2017.1298522 · Cited by 14
Different Heart Rate Patterns During Cardio-Pulmonary Exercise (CPX) Testing in Individuals With Type 1 Diabetes
Moser, O., Tschakert, G., Mueller, A., Groeschl, W., Eckstein, M. L., Koehler, G., Bracken, R. M., Pieber, T. R., & Hofmann, P. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00585 · Cited by 14
The majority of people with type 1 diabetes and multiple daily insulin injections benefit from using continuous glucose monitoring: An analysis based on the GOLD randomized trial ( GOLD‐5 )
Ólafsdóttir, A. F., Bolinder, J., Heise, T., Polonsky, W. H., Ekelund, M., Wijkman, M., Pivodic, A., Ahlén, E., Schwarcz, E., Nyström, T., et al. (2020) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14257 · Cited by 13
Pancreas transplant in type 1 diabetes mellitus: the emerging role of islet cell transplant
Kochar, I. S., & Jain, R. (2021) · Annals of Pediatric Endocrinology & Metabolism · doi:10.6065/apem.2142012.006 · Cited by 16
Association Between Knowledge of Hypoglycemia and Likelihood of Experiencing Hypoglycemia Among Patients with Insulin-Treated Diabetes Mellitus
Almigbal, T. H. (2021) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s327368 · Cited by 14
Management of the Hospitalized Patient With Type I Diabetes Mellitus
Mendez, C. E., & Umpierrez, G. E. (2013) · Hospital Practice · doi:10.3810/hp.2013.08.1072 · Cited by 13
Frequency of adrenal insufficiency in patients with hypoglycemia in an emergency department: A cross-sectional study
Kawahara, T., Tsuji, M., Tominaga, N., Toyama, N., & Toda, M. (2022) · Journal of the Endocrine Society · doi:10.1210/jendso/bvac119 · Cited by 13
Hypothalamic ventromedial COUP-TFII protects against hypoglycemia-associated autonomic failure
Sabra-Makke, L., Maritan, M., Planchais, J., Boutant, M., Pégorier, J. P., Even, P. C., Vasseur-Cognet, M., & Bossard, P. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219262110 · Cited by 13
Impaired awareness of hypoglycemia in children and adolescents with type 1 diabetes mellitus in north of Jordan
Alkhatatbeh, M. J., Abdalqader, N. A., & Alqudah, M. A. Y. (2019) · BMC Endocrine Disorders · doi:10.1186/s12902-019-0441-9 · Cited by 13
Current and future management of diabetic retinopathy: a personalized evidence-based approach
Fante, R. J., Gardner, T. W., & Sundstrom, J. M. (2013) · Diabetes Management · doi:10.2217/dmt.13.50 · Cited by 13
The Health Economic Value of Changes in Glycaemic Control, Weight and Rates of Hypoglycaemia in Type 1 Diabetes Mellitus
McEwan, P. C., Bennett, H., Fellows, J., Priaulx, J., & Bergenheim, K. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162441 · Cited by 13
Ultra-marathon 100 km in an islet-transplanted runner
Codella, R., Adamo, M., Maffi, P., Piemonti, L., Secchi, A., & Luzi, L. (2016) · Acta Diabetologica · doi:10.1007/s00592-016-0938-x · Cited by 13
Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes
Sejling, A., Lange, K. H. W., Frandsen, C. S., Diemar, S. S., Tarnow, L., Faber, J. O., Holst, J. J., Hartmann, B., Hilsted, L. M., Kjær, T. W., et al. (2015) · Diabetologia · doi:10.1007/s00125-015-3616-6 · Cited by 15
Potential approaches to prevent hypoglycemia-associated autonomic failure
Lontchi-Yimagou, E., You, J. Y., Carey, M., Gabriely, I., Shamoon, H., & Hawkins, M. (2018) · Journal of Investigative Medicine · doi:10.1136/jim-2017-000582 · Cited by 12
Estimating risk of consequences following hypoglycaemia exposure using the Hypo-RESOLVE cohort: a secondary analysis of pooled data from insulin clinical trials
Mellor, J., Kuznetsov, D., Heller, S. R., Gall, M.-A., Rosilio, M., Amiel, S. A., Ibberson, M. R., McGurnaghan, S. J., Blackbourn, L. A. K., Berthon, W., et al. (2024) · Diabetologia · doi:10.1007/s00125-024-06225-1 · Cited by 13
Insulin-Induced Hypoglycemia and Its Effect on the Brain
Herzog, R. I., Sherwin, R. S., & Rothman, D. L. (2011) · Diabetes · doi:10.2337/db11-0498 · Cited by 12
Metabolic interventions as adjunctive therapies to insulin in type 1 diabetes: Current clinical landscape and perspectives
Podobnik, J., & Prentice, K. J. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16154 · Cited by 11
Fracture patterns and associated risk factors in pediatric and early adulthood type 1 diabetes: Findings from a nationwide retrospective cohort study
Rasmussen, N. H., Driessen, J. H. M., Kvist, A. V., Souverein, P. C., van den Bergh, J. P., & Vestergaard, P. (2023) · Bone · doi:10.1016/j.bone.2023.116997 · Cited by 11
Acute Hyperglycemia Associated with Psychotic Symptoms in a Patient with Type 1 Diabetes Mellitus: A Case Report.
Sahoo, S., Mehra, A., & Grover, S. (2016) · Europe PMC (PubMed Central) · Cited by 11
Delirium in Diabetic Ketoacidosis: A Case Report
Cebeci, A. N., & Güven, A. (2012) · Journal of Clinical Research in Pediatric Endocrinology · doi:10.4274/jcrpe.478 · Cited by 12
Recommendations for recognizing, risk stratifying, treating, and managing children and adolescents with hypoglycemia
Zucchini, S., Tumini, S., Scaramuzza, A. E., Bonfanti, R., Delvecchio, M., Franceschi, R., Iafusco, D., Lenzi, L., Mozzillo, E., Passanisi, S., et al. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1387537 · Cited by 11
Prevalence of nocturnal hypoglycemia in free-living conditions in adults with type 1 diabetes: What is the impact of daily physical activity?
Molveau, J., RABASA-LHORET, R. P. R., Myette‐Côté, É., Messier, V., Suppère, C., Potter, K. J., Heyman, E., & Tagougui, S. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.953879 · Cited by 10
A bioengineered artificial interstitium supports long-term islet xenograft survival in nonhuman primates without immunosuppression
Oppler, S. H., Stone, L. H., Leishman, D. J., Janecek, J. L., Moore, M. E. G., Rangarajan, P., Willenberg, B. J., O’Brien, T. D., Modiano, J. F., Pheil, N., et al. (2024) · Science Advances · doi:10.1126/sciadv.adi4919 · Cited by 11
Prevalence of Vertebral Fractures in Adults With Type 1 Diabetes: DenSiFy Study (Diabetes Spine Fractures)
Coll, J.-C., Garceau, É., Leslie, W. D., Genest, M., Michou, L., Weisnagel, S. J., Mac‐Way, F., Albert, C., Morin, S. N., RABASA-LHORET, R. P. R., et al. (2022) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgac031 · Cited by 10
Assessing the influence of insulin type (ultra-rapid vs rapid insulin) and exercise timing on postprandial exercise-induced hypoglycaemia risk in individuals with type 1 diabetes: a randomised controlled trial
Molveau, J., Myette‐Côté, É., Tagougui, S., Taleb, N., St-Amand, R., Suppère, C., Bourdeau, V., Heyman, E., & RABASA-LHORET, R. P. R. (2024) · Diabetologia · doi:10.1007/s00125-024-06234-0 · Cited by 11
Safety, efficacy, and cost-effectiveness of insulin degludec U100 versus insulin glargine U300 in adults with type 1 diabetes: a systematic review and indirect treatment comparison
Martín, Zhou, Y., Takagi, T., & Tian, Y. (2022) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-022-01410-x · Cited by 9
Targeted delivery of harmine to xenografted human pancreatic islets promotes robust cell proliferation
Mishra, S., & Streeter, P. R. (2022) · Scientific Reports · doi:10.1038/s41598-022-19453-5 · Cited by 9
Management of Diabetes in Children
Wolfsdorf, J. I., & Garvey, K. C. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00049-4 · Cited by 9
Evaluating the Clinical and Economic Outcomes Associated with Poor Glycemic Control in People with Type 1 Diabetes in the Netherlands
Moes, R. G. J., Huisman, E. L., Malkin, S. J. P., & Hunt, B. (2023) · ClinicoEconomics and Outcomes Research · doi:10.2147/ceor.s391626 · Cited by 8
Macromolecules from mushrooms, venoms, microorganisms, and plants for diabetes treatment - Progress or setback?
Chbel, A., Lafnoune, A., Irahal, I. N., & Bourhim, N. (2024) · Biochimie · doi:10.1016/j.biochi.2024.07.004 · Cited by 9
In Vivo Mouse Abdominal Oxygen Imaging And Assessment of Subcutaneously Implanted Beta Cell Replacement Devices
Canavesi, I., Viswakarma, N., Epel, B., & Kotecha, M. (2024) · Molecular Imaging and Biology · doi:10.1007/s11307-024-01963-5 · Cited by 8

Authors: Cryer, P. E.
Affiliations: Barnes-Jewish Hospital (US)
Corresponding author: Cryer, Philip E.
Venue: Endocrinology and Metabolism Clinics of North America
Publisher: Elsevier BV
Published: 2010-09
Volume: 39
Issue: 3
Pages: 641-654
ISSN: 0889-8529 (ISSN-L)
DOI: 10.1016/j.ecl.2010.05.003
PMC: PMC2923455
OpenAlex: W2009090185
Cited by: 205
References: 68
Citations by year: 2026: 16 · 2025: 20 · 2024: 11 · 2023: 12 · 2022: 12 · 2021: 21 · 2020: 14 · 2019: 13 · 2018: 12 · 2017: 11 · 2016: 9 · 2015: 10 · 2014: 9 · 2013: 16 · 2012: 11
FWCI: 1.50
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Endocrinology and Metabolism Clinics of North America (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (5p60dk020579-35, UL1TR000448)
National Institute of Diabetes and Digestive and Kidney Diseases (R37DK027085, P60-DK20579, R37-DK27085, T32 DK07120, P60-DK-020579, P30DK020579, T32DK007120)
National Center for Research Resources (UL1-RR-24992, M01-RR00036, UL1RR024992, M01RR000036)
NIH Clinical Center
National Center for Advancing Translational Sciences
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Keywords: hypoglycemia, type 1 diabetes, hypoglycemia-associated autonomic failure, iatrogenic hypoglycemia, hyperinsulinemia, insulin excess, hypoglycemia risk factors, insulin secretion
MeSH terms: Blood Glucose, Diabetes Mellitus, Type 1, Humans, Hypoglycemia, Models, Biological, Risk Factors

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Hypoglycemia in Type 1 Diabetes Mellitus

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks