The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Overall alcohol intake, beer, wine, and systemic markers of inflammation in western Europe: results from three MONICA samples (Augsburg, Glasgow, Lille)
Abstract
AIM: Anti-inflammatory effects of moderate alcohol consumption have been proposed to explain why moderate alcohol intake lowers coronary heart disease risk. We investigated the relationship between overall alcohol, beer or wine consumption and markers of systemic inflammation in three different geographical areas in Europe. METHODS AND RESULTS: Cross-sectional samples, each representative of the general population from Germany, Scotland, and France (MONICA Augsburg 1994/95, 2275 men and 2186 women, 25-74 years; Glasgow MONICA 1994/95, 561/616, 25-74 years, and MONICA Lille 1994/95, 581/574, 35-64 years) were studied. Alcohol intake was assessed by standardized interview. Adjusted means of C-reactive protein (CRP), fibrinogen, white blood cell (WBC) count, plasma viscosity (PV), and albumin were calculated among categories of alcohol intake, and separately for beer or wine consumption, by multiple linear regression. Self-reported moderate daily alcohol intake up to 40 g was associated with lower concentrations of CRP, fibrinogen, PV and WBC count, compared to non-drinking and heavy drinking, even after adjustment for various potential confounders. CONCLUSIONS: Moderate consumption of either wine or beer is associated with lower levels of systemic inflammatory markers in three different European areas, suggesting that ethanol itself might be largely responsible for the potential anti-inflammatory effects of these beverages.
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“Similar findings were reported in a cross-sectional study with healthy subjects (n 205) and in subjects with metabolic disorders (n 1653) in Italy (679) .”
From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [679]
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Bruellman, R., Reynolds, C. A., Smolen, A., Evans, D., Gustavson, D. E., & Ellingson, J. M. (2026) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2026.101229
“Specifically, adults with moderate alcohol consumption (e.g., less than two drinks daily) may have lower cytokine levels (Imhof et al., 2004), but such effects are often negligible when excluding alcohol abstainers or participants with health problems, suggesting possible confounding (Kember et…”
Schoormans, D., Bruijnzeels, A. E. C., Deun, K. V., & Mols, F. (2026) · Cancer Epidemiology · doi:10.1016/j.canep.2026.103164
Beer as a functional beverage: Health benefits and bioactive compounds
da Cunha, M. A. A., Marchioro, M. L. K., Couto, G. H., Bortolini, D. G., Rodrigues, S. Á., & Pagnoncelli, M. G. B. (2026) · Beer in Health and Disease Prevention · doi:10.1016/b978-0-443-22332-7.00042-8
Lipid and Inflammation in Atherosclerosis
Ahmado, I., Abela, O. G., Saffia, M. A., Janoudi, A., & Abela, G. S. (2015) · Springer eBooks · doi:10.1007/978-3-319-11161-2_3
Metadata
- Authors
- IMHOF, A., WOODWARD, M., DOERING, A., HELBECQUE, N., LOEWEL, H., AMOUYEL, P., LOWE, G., & KOENIG, W.
- Affiliations
- Universität Ulm (DE)
- The University of Sydney (AU)
- Helmholtz Munich (DE)
- Inserm (FR)
- Glasgow Royal Infirmary (GB)
- Corresponding author
- IMHOF, A
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-12
- Volume
- 25
- Issue
- 23
- Pages
- 2092-2100
- ISSN
- 0195-668X (ISSN-L)
- OpenAlex
- W2155361516
- Cited by
- 204
- References
- 39
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 4 · 2023: 2 · 2022: 9 · 2021: 7 · 2020: 3 · 2019: 5 · 2018: 7 · 2017: 8 · 2016: 8 · 2015: 14 · 2014: 14 · 2013: 7 · 2012: 17
- FWCI
- 8.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Heart Journal (publishedVersion)
- PubMed (publishedVersion)
- Site cant be reached (submittedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- alcohol consumption, beer, wine, systemic inflammation, C-reactive protein, fibrinogen, plasma viscosity, white blood cell count, coronary heart disease risk, MONICA study, heavy drinking
- MeSH terms
- Adult, Aged, Alcohol Drinking, Arteriosclerosis, Beer, Coronary Disease, Cross-Sectional Studies, Female, France, Germany, Humans, Inflammation, Male, Middle Aged, Risk Factors, Scotland, Wine, Biomarkers
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