Cited by 260Atrial Fibrillation Management and OutcomesCardiac, Anesthesia and Surgical OutcomesCardiac Health and Mental Health

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Postoperative atrial fibrillation in patients undergoing aortocoronary bypass surgery carries an eightfold risk of future atrial fibrillation and a doubled cardiovascular mortality

Ahlsson, Anders, Fengsrud, Espen, Bodin, Lennart, Englund, Anders·2010·European Journal of Cardio-Thoracic Surgery

DOI 10.1016/j.ejcts.2009.12.033

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Abstract

OBJECTIVE: This article presents a study of postoperative atrial fibrillation (AF) and its long-term effects on mortality and heart rhythm. METHODS: The study cohort consisted of 571 patients with no history of AF who underwent primary aortocoronary bypass surgery from 1999 to 2000. Postoperative AF occurred in 165/571 patients (28.9%). After a median follow-up of 6 years, questionnaires were obtained from 91.6% of surviving patients and an electrocardiogram (ECG) from 88.6% of all patients. Data from hospitalisations due to arrhythmia or stroke during follow-up were analysed. The causes of death were obtained for deceased patients. RESULTS: In postoperative AF patients, 25.4% had atrial fibrillation at follow-up compared with 3.6% of patients with no AF at surgery (p<0.001). An episode of postoperative AF was the strongest independent risk factor for development of late AF, with an adjusted risk ratio of 8.31 (95% confidence interval (CI) 4.20-16.43). Mortality was 29.7% (49 deaths/165 patients) in the AF group and 14.8% (60 deaths/406 patients) in the non-AF group (p<0.001). Death due to cerebral ischaemia was more common in the postoperative AF group (4.2% vs 0.2%, p<0.001), as was death due to myocardial infarction (6.7% vs 3.0%, p=0.041). Postoperative AF was an age-independent risk factor for late mortality, with an adjusted hazard ratio of 1.57 (95% CI 1.05-2.34). CONCLUSIONS: Postoperative AF patients have an eightfold increased risk of developing AF in the future, and a doubled long-term cardiovascular mortality.

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Authors: Ahlsson, A., Fengsrud, E., Bodin, L., & Englund, A.
Affiliations: Örebro University Hospital (SE)
Corresponding author: Ahlsson, Anders
ORCID: Ahlsson, Anders
Fengsrud, Espen
Englund, Anders
Venue: European Journal of Cardio-Thoracic Surgery
Publisher: Oxford University Press (OUP)
Published: 2010-06
Volume: 37
Issue: 6
Pages: 1353-1359
ISSN: 1010-7940 (ISSN-L)
DOI: 10.1016/j.ejcts.2009.12.033
OpenAlex: W2144902508
Cited by: 259
References: 24
Citations by year: 2026: 11 · 2025: 22 · 2024: 28 · 2023: 17 · 2022: 26 · 2021: 22 · 2020: 27 · 2019: 21 · 2018: 15 · 2017: 17 · 2016: 9 · 2015: 9 · 2014: 15 · 2013: 9 · 2012: 7
FWCI: 4.39
Type: journal article
Language: en
Open access: closed
Locations: European Journal of Cardio-Thoracic Surgery (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac, Anesthesia and Surgical Outcomes
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords: postoperative atrial fibrillation, coronary artery bypass grafting, cardiovascular mortality, stroke, myocardial infarction, risk factors, cardiac arrhythmias
MeSH terms: Aged, Coronary Artery Bypass, Atrial Fibrillation, Brain Ischemia, Electrocardiography, Epidemiologic Methods, Female, Humans, Male, Middle Aged, Myocardial Infarction, Prognosis, Recurrence, Stroke

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Postoperative atrial fibrillation in patients undergoing aortocoronary bypass surgery carries an eightfold risk of future atrial fibrillation and a doubled cardiovascular mortality

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