Cited by 59Heart Failure Treatment and ManagementErythropoietin and Anemia TreatmentCardiovascular and exercise physiology

Fatigue and anaemia in patients with chronic heart failure

Falk, Kristin, Swedberg, Karl, Gaston-Johansson, Fannie, Ekman, Inger·2006·European Journal of Heart Failure

Abstract

BACKGROUND: Fatigue is common in patients with chronic heart failure (CHF) and has great impact on functional ability and daily activity. Although anaemia is associated with fatigue, the relationship between fatigue and anaemia is unclear in CHF. The aim of this study was to describe the fatigue experience and its relationship to haemoglobin (Hb) concentration and to evaluate its effect on health-related quality of life in an unselected hospitalised CHF population. METHODS: Ninety three consecutive patients hospitalised with a diagnosis of CHF, enrolled in the EuroHeart Failure Survey, completed the Multidimensional Fatigue Inventory Scale (MFI-20). New York Heart Association (NYHA) functional class, quality of life and haemoglobin were also assessed. RESULTS: Anaemia (Hb < or = 125 g/L) was found in 31 (33%) patients. The perception of fatigue differed significantly between patients with CHF and healthy individuals. Anaemic patients reported significantly more fatigue compared to non-anaemic patients. Decreased haemoglobin and higher NYHA class explained 30% of the variance in General Fatigue. Perceived fatigue was also inversely related to global health and quality of life. CONCLUSION: Our findings suggest that the subjective experience of fatigue in patients with CHF is associated with low haemoglobin concentration and reduced functional status after controlling for age and sex.

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Crossref · 10.1016/j.ejheart.2006.01.016

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  • Despite not being validated in CHF, the 20-item Multidimensional Fatigue Inventory has been frequently utilized in CHF studies.

    “Despite not being validated in CHF, the 20‐item Multidimensional Fatigue Inventory has been frequently utilized in CHF studies. 14 , 47”

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Authors
Falk, K., Swedberg, K., Gaston-Johansson, F., & Ekman, I.
Affiliations
  • University of Gothenburg (SE)
  • Sahlgrenska University Hospital (SE)
  • Institute of Nursing, Faculty of Health and Caring Sciences, The Sahlgrenska Academy at Góteborg University , Box 457, S-405 30, Góteborg ,
Corresponding author
Falk, Kristin
Venue
European Journal of Heart Failure
Published
2006-10-28
Volume
8
Issue
7
Pages
744-749
ISSN
  • 1388-9842 (ISSN-L)
  • 1879-0844
OpenAlex
W1979281775
Cited by
59
References
45
Citations by year
2026: 1 · 2025: 4 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 3 · 2016: 4 · 2015: 3 · 2014: 1 · 2013: 5 · 2012: 1
FWCI
4.51
Type
journal article
Language
en
Open access
closed
Locations
  • European Journal of Heart Failure (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
  • Health Sciences › Medicine › Hematology › Erythropoietin and Anemia Treatment
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords
chronic heart failure, fatigue, anemia, hemoglobin, health-related quality of life, NYHA functional class, Multidimensional Fatigue Inventory, functional status, hospitalized patients
MeSH terms
Aged, Anemia, Fatigue, Female, Gender Identity, Heart Failure, Hemoglobins, Hospitalization, Humans, Male, Prospective Studies, Quality of Life, Surveys and Questionnaires

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