The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Advanced Glycation End-Products (AGEs) and Heart Failure: Pathophysiology and Clinical Implications
Abstract
Advanced glycation end-products (AGEs) are molecules formed during a non-enzymatic reaction between proteins and sugar residues, called the Maillard reaction. AGEs accumulate in the human body with age, and accumulation is accelerated in the presence of diabetes mellitus. In patients with diabetes, AGE accumulation is associated with the development of cardiac dysfunction. Enhanced AGE accumulation is not restricted to patients with diabetes, but can also occur in renal failure, enhanced states of oxidative stress, and by an increased intake of AGEs. Several lines of evidence suggest that AGEs are related to the development and progression of heart failure in non-diabetic patients as well. Preliminary small intervention studies with AGE cross-link breakers in heart failure patients have shown promising results. In this review, the role of AGEs in the development of heart failure and the role of AGE intervention as a possible treatment for heart failure are discussed.
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Cites
Role of oxidized low density lipoprotein in atherogenesis.
Witztum, J. L., & Steinberg, D. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115499 · Cited by 2,675
Advanced Glycation End Products: Sparking the Development of Diabetic Vascular Injury
Goldin, A., Beckman, J. A., Schmidt, A. M., & Creager, M. A. (2006) · Circulation · doi:10.1161/circulationaha.106.621854 · Cited by 2,261
Foley, R. N., Murray, A. M., Li, S., Herzog, C. A., McBean, A. M., Eggers, P. W., & Collins, A. J. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2004030203 · Cited by 972
Brett, J., Schmidt, A. M., Yan, S. D., Zou, Y. S., Weidman, E., Pinsky, D. J., Nowygrod, R., Neeper, M. P., Przysiecki, C. T., & SHAW, A. R. (1993) · PubMed · Cited by 780
Accumulation of Maillard reaction products in skin collagen in diabetes and aging.
Dyer, D. G., Dunn, J. A., Thorpe, S. R., Bailie, K. E., Lyons, T. J., McCance, D. R., & Baynes, J. W. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116481 · Cited by 769
Improved Arterial Compliance by a Novel Advanced Glycation End-Product Crosslink Breaker
Kass, D. A., Shapiro, E. P., Kawaguchi, M., Capriotti, A. R., Scuteri, A., deGroof, R. C., & Lakatta, E. G. (2001) · Circulation · doi:10.1161/hc3801.097806 · Cited by 727
Schleicher, E. D., Wagner, E., & Nerlich, A. G. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119180 · Cited by 714
Borlaug, B. A., Melenovsky, V., Russell, S. D., Kessler, K., Pacak, K., Becker, L. C., & Kass, D. A. (2006) · Circulation · doi:10.1161/circulationaha.106.632745 · Cited by 699
Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts
Thornalley, P. J. (2003) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2003.08.013 · Cited by 682
Aronson, D. (2003) · Journal of Hypertension · doi:10.1097/00004872-200301000-00002 · Cited by 651
Cited by
Cosentino, F., Grant, P. J., Aboyans, V., Bailey, C. J., Ceriello, A., Delgado, V., Federici, M., Filippatos, G., Grobbee, D. E., Hansen, T. B., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz486 · Cited by 4,763
2023 ESC guidelines for the management of cardiovascular disease in patients with diabetes.
Marx, N., Federici, M., Schütt, K., Müller-Wieland, D., Ajjan, R. A., Antunes, M. J., Christodorescu, R. M., Crawford, C., Di Angelantonio, E., Eliasson, B., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad192 · Cited by 1,642
The glycation of albumin: Structural and functional impacts
Rondeau, P., & Bourdon, E. (2011) · Biochimie · doi:10.1016/j.biochi.2010.12.003 · Cited by 433
Fishman, S. L., Sonmez, H., Basman, C., Singh, V., & Poretsky, L. (2018) · Molecular Medicine · doi:10.1186/s10020-018-0060-3 · Cited by 330
Continuous Glucose Monitoring Systems: A Review
Vashist, S. (2013) · Diagnostics · doi:10.3390/diagnostics3040385 · Cited by 261
Metadata
- Authors
- Hartog, J. W. L., Voors, A. A., Bakker, S. J. L., Smit, A. J., & van Veldhuisen, D. J.
- Venue
- European Journal of Heart Failure
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-12-01
- Volume
- 9
- Issue
- 12
- Pages
- 1146-1155
- ISSN
- 1388-9842 (ISSN-L)
- 1879-0844
- OpenAlex
- W2147752413
- Cited by
- 299
- References
- 54
- FWCI
- 6.81
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hartog, J. W. L., Voors, A. A., Bakker, S. J. L., Smit, A. J., & van Veldhuisen, D. J. (2007). Advanced Glycation End-Products (AGEs) and Heart Failure: Pathophysiology and Clinical Implications. European Journal of Heart Failure. https://doi.org/10.1016/j.ejheart.2007.09.009
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
