Advanced Glycation End Products: Sparking the Development of Diabetic Vascular Injury

Advanced glycation end-products: A review

Singh, R., Barden, A., Mori, T., & Beilin, L. (2001) · Diabetologia · doi:10.1007/s001250051591 · Cited by 2,597 · see citing works

Role of oxidative stress in diabetic complications: a new perspective on an old paradigm.

Baynes, J. W., & Thorpe, S. R. (1999) · Diabetes · doi:10.2337/diabetes.48.1.1 · Cited by 2,441 · see citing works

PROTEIN PRENYLATION: Molecular Mechanisms and Functional Consequences

Zhang, F. L., & Casey, P. J. (1996) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.65.070196.001325 · Cited by 2,018 · see citing works

RAGE Mediates a Novel Proinflammatory Axis

Hofmann, M. A., Drury, S., Fu, C., Qu, W., Taguchi, A., Lu, Y., Avila, C., Kambham, N., Bierhaus, A., Nawroth, P., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80801-6 · Cited by 1,864 · see citing works

Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins.

Neeper, M. P., Schmidt, A. M., Brett, J., Yan, S. D., Wang, F., Pan, Y., Elliston, K. O., Stern, D., & SHAW, A. R. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42138-2 · Cited by 1,542 · see citing works

Advanced protein glycosylation in diabetes and aging

Brownlee, M. D. (1995) · Annual Review of Medicine · doi:10.1146/annurev.med.46.1.223 · Cited by 1,312 · see citing works

Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins

Yan, S. D., Schmidt, A. M., Anderson, G. M., Zhang, J., Brett, J., Zou, Y., Pinsky, D. J., & Stern, D. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36966-1 · Cited by 1,305 · see citing works

The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses

Schmidt, A. M., Yan, S. D., Yan, S. F., & Stern, D. M. (2001) · Journal of Clinical Investigation · doi:10.1172/jci14002 · Cited by 1,256 · see citing works

Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases

Taguchi, A., Blood, D. C., del Toro, G., Canet, A., Lee, D. C., Qu, W., Tanji, N., Lu, Y., Lalla, E., Fu, C., et al. (2000) · Nature · doi:10.1038/35012626 · Cited by 1,217 · see citing works

Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.

Bucala, R., Tracey, K. J., & Cerami, A. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115014 · Cited by 1,162 · see citing works

Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts

Park, L., Raman, K. G., Lee, K. J., Lu, Y., Ferran, L. J., Chow, W. S., Stern, D. M., & Schmidt, A. M. (1998) · Nature Medicine · doi:10.1038/2012 · Cited by 1,103 · see citing works

Structure Elucidation of a Senescence Cross-Link from Human Extracellular Matrix

Sell, D. R., & Monnier, V. M. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)88225-8 · Cited by 1,082 · see citing works

Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE

Wautier, M., Chappey, O., Corda, S., Stern, D. M., Schmidt, A. M., & Wautier, J. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.280.5.e685 · Cited by 1,076 · see citing works

The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses

Schmidt, A. M., Yan, S. D., Yan, S. F., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200114002 · Cited by 1,039 · see citing works

The S100 family of EF-hand calcium-binding proteins: functions and pathology

Schäfer, B. W. (1996) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(96)10020-7 · Cited by 1,005 · see citing works

Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes

Basta, G. (2004) · Cardiovascular Research · doi:10.1016/j.cardiores.2004.05.001 · Cited by 996 · see citing works

Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.

Schmidt, A. M., Hori, O., Chen, J. X., Li, J. F., Crandall, J., Zhang, J., Cao, R., Yan, S. D., Brett, J., & Stern, D. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118175 · Cited by 896 · see citing works

N ε-(Carboxymethyl)Lysine Adducts of Proteins Are Ligands for Receptor for Advanced Glycation End Products That Activate Cell Signaling Pathways and Modulate Gene Expression

Kislinger, T., Fu, C., Huber, B., Qu, W., Taguchi, A., Yan, S. D., Hofmann, M. A., Yan, S. F., Pischetsrieder, M., Stern, D. M., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.44.31740 · Cited by 868 · see citing works

Identification of N epsilon-carboxymethyllysine as a degradation product of fructoselysine in glycated protein.

Ahmed, M. U., Thorpe, S. R., & Baynes, J. W. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)89188-3 · Cited by 864 · see citing works

Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface.

Schmidt, A. M., Vianna, M., Gerlach, M. L., Brett, J., Ryan, J., Kao, J. J., Esposito, C., Hegarty, H. M., Hurley, W. L., & Clauss, M. A. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42137-0 · Cited by 833 · see citing works

Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-κB

Bierhaus, A., Schiekofer, S., Schwaninger, M., Andrassy, M., Humpert, P. M., Chen, J., Hong, M., Luther, T., Henle, T., Klöting, I., et al. (2001) · Diabetes · doi:10.2337/diabetes.50.12.2792 · Cited by 826 · see citing works

Activation of the Receptor for Advanced Glycation End Products Triggers a p21 -dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant Stress

Lander, H. M., Tauras, J. M., Ogiste, J. S., Hori, O., Moss, R. A., & Schmidt, A. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.28.17810 · Cited by 813 · see citing works

Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy

Koschinsky, T., He, C.-J., Mitsuhashi, T., Bucala, R., Liu, C., Buenting, C., Heitmann, K., & Vlassara, H. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.12.6474 · Cited by 792 · see citing works

Activation of Receptor for Advanced Glycation End Products

Schmidt, A. M., Yan, S. D., Wautier, J., & Stern, D. M. (1999) · Circulation Research · doi:10.1161/01.res.84.5.489 · Cited by 792 · see citing works

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

Hammes, H.-P., Du, X., Edelstein, D., Taguchi, T., Matsumura, T., Ju, Q., Lin, J., Bierhaus, A., Nawroth, P., Hannak, D., et al. (2003) · Nature Medicine · doi:10.1038/nm834 · Cited by 785 · see citing works

Accumulation of Maillard reaction products in skin collagen in diabetes and aging.

Dyer, D. G., Dunn, J. A., Thorpe, S. R., Bailie, K., Lyons, T. J., McCance, D. R., & Baynes, J. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116481 · Cited by 770 · see citing works

Advanced glycoxidation end products in commonly consumed foods

Goldberg, T., Cai, W., Peppa, M., Dardaine, V., Baliga, B. S., Uribarri, J., & Vlassara, H. (2004) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2004.05.214 · Cited by 744 · see citing works

Improved Arterial Compliance by a Novel Advanced Glycation End-Product Crosslink Breaker

Kass, D. A., Shapiro, E. P., Kawaguchi, M., Capriotti, A. R., Scuteri, A., deGroof, R. C., & Lakatta, E. G. (2001) · Circulation · doi:10.1161/hc3801.097806 · Cited by 727 · see citing works

Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin.

Lo, T. W. C., Westwood, M. E., McLellan, A. C., Selwood, T., & Thornalley, P. J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)31635-1 · Cited by 695 · see citing works

The S100 family of EF-hand calcium-binding proteins: functions and pathology

Schäfer, B. W., & Heizmann, C. W. (1996) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)80167-8 · Cited by 688 · see citing works

Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy

Vlassara, H., Cai, W., Crandall, J., Goldberg, T., Oberstein, R., Dardaine, V., Peppa, M., & Rayfield, E. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242407999 · Cited by 668 · see citing works

A General Mechanism for Vitamin B 6 -catalyzed Reactions 1

Metzler, D. E., Ikawa, M., & Snell, E. E. (1954) · Journal of the American Chemical Society · doi:10.1021/ja01632a004 · Cited by 638 · see citing works

Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions.

Schmidt, A. M., Hori, O., Brett, J., Yan, S. D., Wautier, J., & Stern, D. (1994) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.14.10.1521 · Cited by 636 · see citing works

Receptor for Advanced Glycation End Products (RAGE)-mediated Neurite Outgrowth and Activation of NF-κB Require the Cytoplasmic Domain of the Receptor but Different Downstream Signaling Pathways

Huttunen, H. J., Fages, C., & Rauvala, H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.28.19919 · Cited by 629 · see citing works

RAGE Blockade Stabilizes Established Atherosclerosis in Diabetic Apolipoprotein E–Null Mice

Bucciarelli, L. G., Wendt, T., Qu, W., Lu, Y., Lalla, E., Rong, L., Goova, M. T., Moser, B., Kislinger, T., Lee, D. C., et al. (2002) · Circulation · doi:10.1161/01.cir.0000039325.03698.36 · Cited by 562 · see citing works

Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats.

Wautier, J., Zoukourian, C., Chappey, O., Wautier, M.-P., Guillausseau, P.-J., Cao, R. Y., Hori, O., Stern, D., & Schmidt, A. M. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118397 · Cited by 551 · see citing works

Advanced Glycation End Products Activate Endothelium Through Signal-Transduction Receptor RAGE

Basta, G., Lazzerini, G., Massaro, M., Simoncini, T., Tanganelli, P., Fu, C., Kislinger, T., Stern, D. M., Schmidt, A. M., & Caterina, R. D. (2002) · Circulation · doi:10.1161/hc0702.104183 · Cited by 544 · see citing works

Characterization and Functional Analysis of the Promoter of RAGE, the Receptor for Advanced Glycation End Products

Li, J., & Schmidt, A. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.26.16498 · Cited by 525 · see citing works

Glycation, Inflammation, and RAGE: A Scaffold for the Macrovascular Complications of Diabetes and Beyond

Yan, S. F., Ramasamy, R., Naka, Y., & Schmidt, A. M. (2003) · Circulation Research · doi:10.1161/01.res.0000103862.26506.3d · Cited by 513 · see citing works

Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency.

Bucala, R., Makita, Z., Vega, G., Grundy, S. M., Koschinsky, T., Cerami, A., & Vlassara, H. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.20.9441 · Cited by 471 · see citing works

Glycation, Glycoxidation, and Cross-Linking of Collagen by Glucose: Kinetics, Mechanisms, and Inhibition of Late Stages of the Maillard Reaction

Fu, M.-X., Wells‐Knecht, K. J., Blackledge, J. A., Lyons, T. J., Thorpe, S. R., & Baynes, J. (1994) · Diabetes · doi:10.2337/diab.43.5.676 · Cited by 464 · see citing works

Randomized Trial of an Inhibitor of Formation of Advanced Glycation End Products in Diabetic Nephropathy

Bolton, W. K., Cattran, D. C., Williams, M. E., Adler, S. G., Appel, G. B., Cartwright, K. J., Foiles, P. G., Freedman, B. I., Raskin, P., Ratner, R. E., et al. (2004) · American Journal of Nephrology · doi:10.1159/000075627 · Cited by 460 · see citing works

A Breaker of Advanced Glycation End Products Attenuates Diabetes-Induced Myocardial Structural Changes

Candido, R., Forbes, J. M., Thomas, M. C., Thallas, V., Dean, R. G., Burns, W. C., Tikellis, C., Ritchie, R. H., Twigg, S. M., Cooper, M. E., et al. (2003) · Circulation Research · doi:10.1161/01.res.0000065620.39919.20 · Cited by 449 · see citing works

Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion.

Morigi, M., Angioletti, S., Imberti, B., Donadelli, R., Micheletti, G., Figliuzzi, M., Remuzzi, A., Zoja, C., & Remuzzi, G. (1998) · Journal of Clinical Investigation · doi:10.1172/jci656 · Cited by 439 · see citing works

Blockade of Receptor for Advanced Glycation End-Products Restores Effective Wound Healing in Diabetic Mice

Goova, M. T., Li, J., Kislinger, T., Qu, W., Lu, Y., Bucciarelli, L. G., Nowygrod, S., Wolf, B. M., Caliste, X. A., Yan, S. F., et al. (2001) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)61723-3 · Cited by 432 · see citing works

Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): a new member of the AGE-receptor complex

Vlassara, H., Li, Y. M., Imani, F., Wojciechowicz, D., Yang, Z., Liu, F.-T., & Cerami, A. (1995) · Molecular Medicine · doi:10.1007/bf03401604 · Cited by 421 · see citing works

Endothelial receptor-mediated binding of glucose-modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties.

Esposito, C., Gerlach, H., Brett, J., Stern, D., & Vlassara, H. (1989) · The Journal of Experimental Medicine · doi:10.1084/jem.170.4.1387 · Cited by 380 · see citing works

Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat

Degenhardt, T. P., Alderson, N. L., Arrington, D. D., Beattie, R. J., Basgen, J. M., Steffes, M. W., Thorpe, S. R., & Baynes, J. (2002) · Kidney International · doi:10.1046/j.1523-1755.2002.00207.x · Cited by 378 · see citing works

Role of the Maillard Reaction in Aging of Tissue Proteins

Frye, E. B., Degenhardt, T. P., Thorpe, S. R., & Baynes, J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.30.18714 · Cited by 371 · see citing works

Nonenzymatic glycosylation in vitro and in bovine endothelial cells alters basic fibroblast growth factor activity. A model for intracellular glycosylation in diabetes.

Giardino, I., Edelstein, D., & Brownlee, M. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117296 · Cited by 364 · see citing works

The AGE Inhibitor Pyridoxamine Inhibits Development of Retinopathy in Experimental Diabetes

Stitt, A. W., Gardiner, T. A., Anderson, N. L., Canning, P., Frizzell, N., Duffy, N., Boyle, C., Januszewski, A. S., Chachich, M. E., Baynes, J., et al. (2002) · Diabetes · doi:10.2337/diabetes.51.9.2826 · Cited by 355 · see citing works

Advanced glycation end products (AGEs) on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: a link between surface-associated AGEs and diabetic complications.

Wautier, J., Wautier, M.-P., Schmidt, A. M., Anderson, G. M., Hori, O., Zoukourian, C., Capron, L., Chappey, O., Yan, S. D., & Brett, J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.16.7742 · Cited by 353 · see citing works

Mechanistic Studies of Advanced Glycosylation End Product Inhibition by Aminoguanidine

Edelstein, D., & Brownlee, M. (1992) · Diabetes · doi:10.2337/diab.41.1.26 · Cited by 345 · see citing works

Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins.

Li, Y. M., Mitsuhashi, T., Wojciechowicz, D. C., Shimizu, N., Li, J., Stitt, A. W., He, C., Banerjee, D., & Vlassara, H. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.20.11047 · Cited by 340 · see citing works

An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness

Asif, M., Egan, J. J., Vasan, S., Jyothirmayi, G. N., Masurekar, M. R., Lopez, S., Williams, C., Torres, R. L., Wagle, D., Ulrich, P. C., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.040558497 · Cited by 336 · see citing works

Restriction of Dietary Glycotoxins Reduces Excessive Advanced Glycation End Products in Renal Failure Patients

Uribarri, J., Peppa, Μ., Cai, W., Goldberg, T., Lu, M. M., He, C., & Vlassara, H. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000051593.41395.b9 · Cited by 331 · see citing works

Role of fructose in glycation and cross-linking of proteins

McPherson, J. D., Shilton, B. H., & Walton, D. J. (1988) · Biochemistry · doi:10.1021/bi00406a016 · Cited by 329 · see citing works

Receptor for advanced glycation end products (AGEs) has a central role in vessel wall interactions and gene activation in response to circulating AGE proteins.

Schmidt, A. M., Hasu, M., Popov, D., Zhang, J. H., Chen, J., Yan, S. D., Brett, J., Cao, R. Y., Kuwabara, K., & Costache, G. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.19.8807 · Cited by 327 · see citing works

Advanced Glycation End Products and Endothelial Dysfunction in Type 2 Diabetes

Tan, K. C. B., Chow, W.-S., Ai, V. H. G., Metz, C. N., Bucala, R., & Lam, K. S. L. (2002) · Diabetes Care · doi:10.2337/diacare.25.6.1055 · Cited by 318 · see citing works

Advanced Glycation End Product Interventions Reduce Diabetes-Accelerated Atherosclerosis

Forbes, J. M., Yee, L. T. L., Thallas, V., Lassila, M., Candido, R., Jandeleit-Dahm, K. A. M., Thomas, M. C., Burns, W. C., Deemer, E. K., Thorpe, S. R., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.7.1813 · Cited by 314 · see citing works

RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease

Bucciarelli, L. G., Wendt, T., Rong, L., Lalla, E., Hofmann, M. A., Goova, M. T., Taguchi, A., Yan, S. F., Yan, S. D., Stern, D. M., et al. (2002) · Cellular and Molecular Life Sciences (CMLS) · doi:10.1007/s00018-002-8491-x · Cited by 304 · see citing works

The AGE‐receptor in the pathogenesis of diabetic complications

Vlassara, H. (2001) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.233 · Cited by 301 · see citing works

Angiotensin II Receptor Antagonists and Angiotensin-Converting Enzyme Inhibitors Lower In Vitro the Formation of Advanced Glycation End Products

Miyata, T., de Strihou, C. V. Y., Ueda, Y., Ichimori, K., Inagi, R., Onogi, H., Ishikawa, N., Nangaku, M., & Kurokawa, K. (2002) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000032418.67267.f2 · Cited by 287 · see citing works

Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorins I and II and a 48 kd protein

Kelleher, D. J., Kreibich, G., & Gilmore, R. (1992) · Cell · doi:10.1016/0092-8674(92)90118-v · Cited by 286 · see citing works

Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells.

Quehenberger, P., Bierhaus, A., Fasching, P., Muellner, C., Klevesath, M. S., Hong, M., Stier, G., Sattler, M., Schleicher, E., Speiser, W., et al. (2000) · Diabetes · doi:10.2337/diabetes.49.9.1561 · Cited by 283 · see citing works

Reduction of the Accumulation of Advanced Glycation End Products by ACE Inhibition in Experimental Diabetic Nephropathy

Forbes, J. M., Cooper, M. E., Thallas, V., Burns, W. C., Thomas, M. C., Brammar, G. C., Lee, F., Grant, S. L., Burrell, L. M., Jerums, G., et al. (2002) · Diabetes · doi:10.2337/diabetes.51.11.3274 · Cited by 276 · see citing works

Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin

Okamoto, T., Yamagishi, S., Inagaki, Y., Amano, S., Koga, K., Abe, R., Takeuchi, M., Ohno, S., Yoshimura, A., & Makita, Z. (2002) · The FASEB Journal · doi:10.1096/fj.02-0030fje · Cited by 258 · see citing works

Immunohistochemical Evidence for an Increased Oxidative Stress and Carbonyl Modification of Proteins in Diabetic Glomerular Lesions

SUZUKI, D., Miyata, T., Saotome, N., Horie, K., Inagi, R., Yasuda, Y., Uchida, K., Izuhara, Y., Yagame, M., Sakai, H., et al. (1999) · Journal of the American Society of Nephrology · doi:10.1681/asn.v104822 · Cited by 254 · see citing works

Hemoglobin-AGE: A Circulating Marker of Advanced Glycosylation

Makita, Z., Vlassara, H., Rayfield, E. J., Cartwright, K. J., Friedman, E. A., Rodby, R. A., Cerami, A., & Bucala, R. (1992) · Science · doi:10.1126/science.1411574 · Cited by 251 · see citing works

Three Genes in the Human MHC Class III Region near the Junction with the Class II: Gene for Receptor of Advanced Glycosylation End Products, PBX2 Homeobox Gene and a Notch Homolog, Human Counterpart of Mouse Mammary Tumor Gene int-3

Sugaya, K., Fukagawa, T., Matsumoto, K., Mita, K., Takahashi, E., Ando, A., Inoko, H., & Ikemura, T. (1994) · Genomics · doi:10.1006/geno.1994.1517 · Cited by 242 · see citing works

Platelet Abnormalities in Diabetes Mellitus

Winocour, P. D. (1992) · Diabetes · doi:10.2337/diab.41.2.s26 · Cited by 237 · see citing works

Constitutive nitric oxide synthase expression in retinal vascular endothelial cells is suppressed by high glucose and advanced glycation end products.

Chakravarthy, U., Hayes, R., Stitt, A. W., McAuley, E., & Archer, D. B. (1998) · Diabetes · doi:10.2337/diabetes.47.6.945 · Cited by 237 · see citing works

Advanced Glycation End Product (AGE)–Mediated Induction of Tissue Factor in Cultured Endothelial Cells Is Dependent on RAGE

Bierhaus, A., Illmer, T., Kasper, M. E., Luther, T., Quehenberger, P., Tritschler, H., Wahl, P. M., Ziegler, R., Müller, M., & Nawroth, P. P. (1997) · Circulation · doi:10.1161/01.cir.96.7.2262 · Cited by 220 · see citing works

Advanced glycosylation endproducts block the antiproliferative effect of nitric oxide. Role in the vascular and renal complications of diabetes mellitus.

Hogan, M. M., Cerami, A., & Bucala, R. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115928 · Cited by 208 · see citing works

Glycation induces expansion of the molecular packing of collagen

Tanaka, S., Avigad, G., Brodsky, B., et al. (1988) · Journal of Molecular Biology · doi:10.1016/0022-2836(88)90015-0 · Cited by 205 · see citing works

Nonenzymatic Glycosylation Products on Collagen Covalently Trap Low-Density Lipoprotein

Brownlee, M., Vlassara, H., & Cerami, A. (1985) · Diabetes · doi:10.2337/diab.34.9.938 · Cited by 205 · see citing works

FEEL-1 and FEEL-2 Are Endocytic Receptors for Advanced Glycation End Products

Tamura, Y., Adachi, H., Osuga, J.-I., Ohashi, K., Yahagi, N., Sekiya, M., Okazaki, H., Tomita, S., Iizuka, Y., Shimano, H., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210211200 · Cited by 197 · see citing works

High molecular weight hyaluronic acid inhibits advanced glycation endproduct‐induced NF‐κB activation and cytokine expression

Neumann, A., Schinzel, R., Palm, D., Riederer, P. F., & Münch, G. W. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00731-0 · Cited by 195 · see citing works

Impairment of vascular endothelial nitric oxide synthase activity by advanced glycation end products

Biao, X., Chibber, R., Ruggiero, D., Kohner, E., Ritter, J., & Ferro, A. (2003) · The FASEB Journal · doi:10.1096/fj.02-0490fje · Cited by 195 · see citing works

Altered cellular interactions between endothelial cells and nonenzymatically glucosylated laminin/type IV collagen.

Haitoglou, C., Tsilibary, E. C., Brownlee, M., & CHARONIS, A. S. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42287-9 · Cited by 194 · see citing works

Advanced glycation endproducts inhibit prostacyclin production and induce plasminogen activator inhibitor-1 in human microvascular endothelial cells

Yamagishi, S., Fujimori, H., Yonekura, H., Yamamoto, Y., & Yamamoto, H. (1998) · Diabetologia · doi:10.1007/s001250051089 · Cited by 193 · see citing works

Two novel rat liver membrane proteins that bind advanced glycosylation endproducts: relationship to macrophage receptor for glucose-modified proteins.

Yang, Z., Makita, Z., Horii, Y., Brunelle, S., Cerami, A., Sehajpal, P. K., Suthanthiran, M., & Vlassara, H. (1991) · The Journal of Experimental Medicine · doi:10.1084/jem.174.3.515 · Cited by 191 · see citing works

Aminoguanidine prevents age-related arterial stiffening and cardiac hypertrophy

Corman, B., Duriez, M., Poitevin, P., Heudes, D., Bruneval, P., Tedgui, A., & Levy, B. I. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.3.1301 · Cited by 189 · see citing works

Acute Hyperglycemia Causes Intracellular Formation of CML and Activation of ras, p42/44 MAPK, and Nuclear Factor κB in PBMCs

Schiekofer, S., Andrassy, M., Chen, J., Rudofsky, G., Schneider, J. G., Wendt, T., Stefan, N., Humpert, P. M., Fritsche, A., Stümvoll, M., et al. (2003) · Diabetes · doi:10.2337/diabetes.52.3.621 · Cited by 180 · see citing works

High Levels of Dietary Advanced Glycation End Products Transform Low-Dersity Lipoprotein Into a Potent Redox-Sensitive Mitogen-Activated Protein Kinase Stimulant in Diabetic Patients

Cai, W., He, J. C., Zhu, L., Peppa, M., Lu, C., Uribarri, J., & Vlassara, H. (2004) · Circulation · doi:10.1161/01.cir.0000135587.92455.0d · Cited by 177 · see citing works

Scavenger Receptor Class B Type I-mediated Reverse Cholesterol Transport Is Inhibited by Advanced Glycation End Products

Ohgami, N., Nagai, R., Miyazaki, A., Ikemoto, M., Arai, H., Horiuchi, S., & Nakayama, H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m011613200 · Cited by 176 · see citing works

Scavenger receptors for oxidized and glycated proteins

Horiuchi, S., Sakamoto, Y., & Sakai, M. (2003) · Amino Acids · doi:10.1007/s00726-003-0029-5 · Cited by 175 · see citing works

PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products

Throckmorton, D. C., Brogden, A. P., Min, B., Rasmussen, H., & Kashgarian, M. J. (1995) · Kidney International · doi:10.1038/ki.1995.274 · Cited by 174 · see citing works

RAGE: a new target for the prevention and treatment of the vascular and inflammatory complications of diabetes.

Schmidt, A., & Stern, D. (2000) · Trends in endocrinology and metabolism · doi:10.1016/s1043-2760(00)00311-8 · Cited by 173 · see citing works

The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats

Alderson, N. L., Chachich, M. E., Youssef, N., Beattie, R. J., Nachtigal, M., Thorpe, S. R., & Baynes, J. (2003) · Kidney International · doi:10.1046/j.1523-1755.2003.00027.x · Cited by 171 · see citing works

Laminin Alterations After In Vitro Nonenzymatic Glycosylation

CHARONIS, A. S., Reger, L. A., Dege, J. E., Kouzi‐Koliakos, K., Furcht, L. T., Wohlhueter, R. M., & Tsilibary, E. C. (1990) · Diabetes · doi:10.2337/diab.39.7.807 · Cited by 164 · see citing works

Renoprotective effects of a novel inhibitor of advanced glycation

Forbes, J. M., Soulis, T., Thallas, V., Panagiotopoulos, S., Long, D. M., Vasan, S., Wagle, D., Jerums, G., & Cooper, M. E. (2001) · Diabetologia · doi:10.1007/s001250051587 · Cited by 161 · see citing works

The Vitamin B6 Group. V. The Reversible Interconversion of Pyridoxal and Pyridoxamine by Transamination Reactions

Snell, E. E. (1945) · Journal of the American Chemical Society · doi:10.1021/ja01218a013 · Cited by 152 · see citing works

Attenuation of Extracellular Matrix Accumulation in Diabetic Nephropathy by the Advanced Glycation End Product Cross-Link Breaker ALT-711 via a Protein Kinase C-α−Dependent Pathway

Thallas‐Bonke, V., Lindschau, C., Rizkalla, B., Bach, L. A., Boner, G., Meier, M., Haller, H. G., Cooper, M. E., & Forbes, J. M. (2004) · Diabetes · doi:10.2337/diabetes.53.11.2921 · Cited by 151 · see citing works

The dark side of glucose

Schmidt, A. M., Yan, S. D., & Stern, D. M. (1995) · Nature Medicine · doi:10.1038/nm1095-1002 · Cited by 150 · see citing works

The effect of nonenzymatic glucosylation on the binding of the main noncollagenous NC1 domain to type IV collagen.

Tsilibary, E. C., CHARONIS, A. S., Reger, L. A., Wohlhueter, R. M., & Furcht, L. T. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)68925-2 · Cited by 147 · see citing works

Advanced glycation and endothelial functions: A link towards vascular complications in diabetes

Armando Rojas, R., & Morales, M. A. (2004) · Life Sciences · doi:10.1016/j.lfs.2004.09.011 · Cited by 145 · see citing works

Modification of Proteins In Vitro by Physiological Levels of Glucose

Voziyan, P., Khalifah, R. G., Thibaudeau, C., Yıldız, A., Jacob, J., Serianni, A. S., & Hudson, B. G. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307155200 · Cited by 142 · see citing works

RAGE Axis

Naka, Y., Bucciarelli, L. G., Wendt, T., Lee, L. K., Rong, L., Ramasamy, R., Yan, S. F., & Schmidt, A. M. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000133191.71196.90 · Cited by 138 · see citing works

Glycated and Oxidized Protein Degradation Products Are Indicators of Fasting and Postprandial Hyperglycemia in Diabetes

Ahmed, N., Babaei‐Jadidi, R., Howell, S. K., Thornalley, P. J., & Beisswenger, P. J. (2005) · Diabetes Care · doi:10.2337/diacare.28.10.2465 · Cited by 138 · see citing works

Diabetes Enhances Lectin-like Oxidized LDL Receptor-1 (LOX-1) Expression in the Vascular Endothelium: Possible Role of LOX-1 Ligand and AGE

Chen, M., Nagase, M., Fujita, T., et al. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5674 · Cited by 135 · see citing works

Lectin‐like oxidized low density lipoprotein receptor‐1 (LOX‐1) serves as an endothelial receptor for advanced glycation end products (AGE)

Jono, T., Miyazaki, A., Nagai, R., Sawamura, T., Kitamura, T., & Horiuchi, S. (2002) · FEBS Letters · doi:10.1016/s0014-5793(01)03325-7 · Cited by 133 · see citing works

Regulation of Endothelial Nitric Oxide Synthase Expression by Albumin-Derived Advanced Glycosylation End Products

Armando Rojas, R., Romay, S., González, D., Sanchez, M. B. H., Delgado, R., & Otero, K. (2000) · Circulation Research · doi:10.1161/01.res.86.3.e50 · Cited by 126 · see citing works

The endothelial cell binding site for advanced glycation end products consists of a complex: an integral membrane protein and a lactoferrin-like polypeptide

Schmidt, A. M., Mora, R., Cao, R. Y., Yan, S. D., Brett, J., Ramakrishnan, R., Tsang, T. C., Simionescu, M., & Stern, D. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36965-x · Cited by 123 · see citing works

THE VITAMIN ACTIVITIES OF “PYRIDOXAL” AND “PYRIDOXAMINE”

Snell, E. E. (1944) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71972-8 · Cited by 120 · see citing works

The effect of advanced glycation end-product formation upon cell-matrix interactions

Paul, R. G., & Bailey, A. J. (1999) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(99)00023-0 · Cited by 119 · see citing works

Detection of 3-deoxyfructose and 3-deoxyglucosone in human urine and plasma: Evidence for intermediate stages of the maillard reaction in vivo

Knecht, K. J., Feather, M. S., & Baynes, J. (1992) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(92)90146-n · Cited by 118 · see citing works

ALT-946 and Aminoguanidine, Inhibitors of Advanced Glycation, Improve Severe Nephropathy in the Diabetic Transgenic (mREN-2)27 Rat

Wilkinson‐Berka, J. L., Kelly, D. J., Koerner, S. M., Jaworski, K., Davis, B., Thallas, V., & Cooper, M. E. (2002) · Diabetes · doi:10.2337/diabetes.51.11.3283 · Cited by 105 · see citing works

Modification of vitronectin by advanced glycation alters functional properties in vitro and in the diabetic retina.

Hammes, H. P., Weiss, A., Hess, S., Araki, N., Horiuchi, S., Brownlee, M., & Preissner, K. T. (1996) · PubMed · Cited by 104 · see citing works

Advanced Glycation End Products-Induced Gene Expression of Scavenger Receptors in Cultured Human Monocyte-Derived Macrophages

Iwashima, Y., Eto, M., Hata, A., Kaku, K., Horiuchi, S., Ushikubi, F., & Sano, H. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3685 · Cited by 101 · see citing works

Advanced glycation end products induce apoptosis and procoagulant activity in cultured human umbilical vein endothelial cells

Min, C., Kang, E., Yu, S.-H., Shinn, S.-H., & Kim, Y. (1999) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(99)00094-7 · Cited by 97 · see citing works

Effect of antioxidants and ACE inhibition on chemical modification of proteins and progression of nephropathy in the streptozotocin diabetic rat

Alderson, N. L., Chachich, M. E., Frizzell, N., Canning, P., Metz, T., Januszewski, A. S., Youssef, N., Stitt, A. W., Baynes, J., & Thorpe, S. R. (2004) · Diabetologia · doi:10.1007/s00125-004-1474-8 · Cited by 97 · see citing works

Atherogenesis and Advanced Glycation: Promotion, Progression, and Preventiona

Stitt, A. W., Bucala, R., & Vlassara, H. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb51994.x · Cited by 82 · see citing works

Identification of p90, a Prominent Tyrosine-phosphorylated Protein in Fibroblast Growth Factor-stimulated Cells, as 80K-H

Goh, K. C., Lim, Y. P., Ong, S. H., Siak, C. B., Cao, X., Tan, Y. H., & Guy, G. R. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.10.5832 · Cited by 67 · see citing works

Cellular Contraction of Collagen Lattices Is Inhibited by Nonenzymatic Glycation

Howard, E. W., Benton, R., Ahern-Moore, J. S., & Tomasek, J. J. (1996) · Experimental Cell Research · doi:10.1006/excr.1996.0308 · Cited by 67 · see citing works

The Insulin Gene Variable Number Tandem Repeat Class I/III Polymorphism Is in Linkage Disequilibrium With Birth Weight but Not Type 2 Diabetes in the Pima Population

Lindsay, R. S., Hanson, R. L., Wiedrich, C., Knowler, W. C., Bennett, P. H., & Baier, L. J. (2003) · Diabetes · doi:10.2337/diabetes.52.1.187 · Cited by 67 · see citing works

Advanced glycosylation end products induced tissue factor expression in human monocyte-like U937 cells and increased tissue factor expression in monocytes from diabetic patients

Ichikawa, K., Yoshinari, M., Iwase, M., et al. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(97)00221-9 · Cited by 67 · see citing works

In vivo and in vitro evidence for the glycoxidation of low density lipoprotein in human atherosclerotic plaques

Imanaga, Y., Sakata, N., Takebayashi, S., Matsunaga, A., Sasaki, J., Arakawa, K., Nagai, R., Horiuchi, S., Itabe, H., & Takano, T. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00396-2 · Cited by 65 · see citing works

Crosslink breakers: a new approach to cardiovascular therapy

Sušić, D., Varagić, J., Ahn, J., & Frohlich, E. D. (2004) · Current Opinion in Cardiology · doi:10.1097/01.hco.0000127135.73849.4f · Cited by 63 · see citing works

Administration of AGEs in vivo induces extracellular matrix gene expression

Striker, L. J., & Striker, G. E. (1996) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/11.supp5.62 · Cited by 62 · see citing works

Glycated low-density lipoprotein attenuates shear stress-induced nitric oxide synthesis by inhibition of shear stress-activated L-arginine uptake in endothelial cells.

Posch, K., Simecek, S., Wascher, T. C., et al. (1999) · Diabetes · doi:10.2337/diabetes.48.6.1331 · Cited by 59 · see citing works

Advanced glycosylation end products in skin, serum, saliva and urine and its association with complications of patients with Type 2 diabetes mellitus

Garay‐Sevilla, M. E., Regalado, J. C., Malacara, J. M., Nava, L. E., Wróbel, K., Castro-Rivas, A., & Wróbel, K. (2005) · Journal of Endocrinological Investigation · doi:10.1007/bf03345377 · Cited by 58 · see citing works

Getting Better Without AGE

Kass, D. A. (2003) · Circulation Research · doi:10.1161/01.res.0000069362.52165.c9 · Cited by 56 · see citing works

Inhibitor for advanced glycation end products formation attenuates hypertension and oxidative damage in genetic hypertensive rats

Mizutani, K.-I., Ikeda, K., Tsuda, K., & Yamori, Y. (2002) · Journal of Hypertension · doi:10.1097/00004872-200208000-00024 · Cited by 54 · see citing works

Release of Glomerular Heparan-35SO4 Proteoglycan by Heparin From Glomeruli of Streptozocin-Induced Diabetic Rats

Klein, D. J., Oegema, T. R., & Brown, D. M. (1989) · Diabetes · doi:10.2337/diab.38.1.130 · Cited by 53 · see citing works

Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesis

Sakata, N. (2001) · Cardiovascular Research · doi:10.1016/s0008-6363(00)00262-5 · Cited by 52 · see citing works

Nitric oxide inhibits the formation of advanced glycation end products

Asahi, K., Ichimori, K., Nakazawa, H. K., et al. (2000) · Kidney International · doi:10.1111/j.1523-1755.2000.00340.x · Cited by 47 · see citing works

The Role of Reactive Oxygen Species in Insulin Signaling in the Vasculature

Frank, G. D., Eguchi, S., & Motley, E. D. (2005) · Antioxidants and Redox Signaling · doi:10.1089/ars.2005.7.1053 · Cited by 46 · see citing works

Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose

Pomero, F., Min, A. R. M., Selva, M. L., Allione, A., Molinatti, G. M., & Porta, M. (2001) · Acta Diabetologica · doi:10.1007/s005920170010 · Cited by 44 · see citing works

Induction of TNFα and IL-1β mRNA in monocytes by methylglyoxal- and advanced glycated endproduct-modified human serum albumin

Webster, L., Abordo, E. A., Thornalley, P. J., et al. (1997) · Biochemical Society Transactions · doi:10.1042/bst025250s · Cited by 44 · see citing works

Pathological Roles of Advanced Glycation End Product Receptors SR‐A and CD36

Horiuchi, S., Unno, Y., Usui, H. K., Shikata, K., Takaki, K., Koito, W., SAKAMOTO, Y., Nagai, R., MAKINO, K., SASAO, A., et al. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1333.076 · Cited by 39 · see citing works

CD36 Is Not Involved in Scavenger Receptor–Mediated Endocytic Uptake of Glycolaldehyde- and Methylglyoxal-Modified Proteins by Liver Endothelial Cells

Nakajou, K., Horiuchi, S., Sakai, M., Hirata, K., Tanaka, M. R., Takeya, M., Kai, T., & Otagiri, M. (2005) · The Journal of Biochemistry · doi:10.1093/jb/mvi071 · Cited by 28 · see citing works

Roles of advanced glycation end-products in the progression of diabetic nephropathy

Makino, H., Shikata, K., Kushiro, M., et al. (1996) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/11.supp5.76 · Cited by 26 · see citing works

Molecular genetics of human renal cell tumours

Kovács, G. (1996) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/11.supp6.62 · Cited by 23 · see citing works

In-Vitro Carboxymethylation of Low Density Lipoprotein Alters its Metabolism Via the High-Affinity Receptor

Gempel, K. E., Gerbitz, K.-D., Olgemöller, B., et al. (1993) · Hormone and Metabolic Research · doi:10.1055/s-2007-1002089 · Cited by 19 · see citing works

Accumulation of Nσ-(Carboxy-methyl)lysine and Changes inGlomerular Extracellular MatrixComponents in Otsuka Long-EvansTokushima Fatty Rat:A Model of Spontaneous NIDDM

Kushiro, M., Shikata, K., Sugimoto, H., et al. (1998) · ˜The œNephron journals/Nephron journals · doi:10.1159/000045093 · Cited by 11 · see citing works

Oxidative stress and diabetic complications

Giacco, F., & Brownlee, M. (2010) · Circulation Research · doi:10.1161/circresaha.110.223545 · Cited by 5,461 · see citing works

Macrophages, inflammation, and insulin resistance

Olefsky, J. M., & Glass, C. K. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135846 · Cited by 2,733 · see citing works

Advanced glycation end products in foods and a practical guide to their reduction in the diet

Uribarri, J., Woodruff, S., Goodman, S., Cai, W., Chen, X., Pyzik, R., Yong, A., Striker, G. E., & Vlassara, H. (2010) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2010.03.018 · Cited by 1,289 · see citing works

The antioxidant properties of serum albumin

Roche, M., Rondeau, P., Singh, N. R., Tarnus, E., & Bourdon, E. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.04.057 · Cited by 1,255 · see citing works

Role of advanced glycation end products in cellular signaling

Ott, C., Jacobs, K., Haucke, E., Navarrete Santos, A., Grune, T., & Simm, A. (2014) · Redox Biology · doi:10.1016/j.redox.2013.12.016 · Cited by 1,150 · see citing works

Molecular mechanisms of diabetic cardiomyopathy

Bugger, H., & Abel, E. D. (2014) · Diabetologia · doi:10.1007/s00125-014-3171-6 · Cited by 903 · see citing works

Circulating Glycotoxins and Dietary Advanced Glycation Endproducts: Two Links to Inflammatory Response, Oxidative Stress, and Aging

Uribarri, J., Cai, W., Peppa, M., Goodman, S., Ferrucci, L., Striker, G., & Vlassara, H. (2007) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/62.4.427 · Cited by 570 · see citing works

Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes

Soro-Paavonen, A., Watson, A. M. D., Li, J., Paavonen, K., Koitka, A., Calkin, A. C., Barit, D., Coughlan, M. T., Drew, B. G., Lancaster, G. I., et al. (2008) · Diabetes · doi:10.2337/db07-1808 · Cited by 407 · see citing works

Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury

Rungratanawanich, W., Qu, Y., Wang, X., Essa, M. M., & Song, B.-J. (2021) · Experimental & Molecular Medicine · doi:10.1038/s12276-021-00561-7 · Cited by 411 · see citing works

Advanced glycation end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases

Byun, K., Yoo, Y., Son, M., Lee, J., Jeong, G.-B., Park, Y. M., Salekdeh, G. H., & Lee, B. (2017) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2017.02.030 · Cited by 357 · see citing works

Analysis of advanced glycation endproducts in selected food items by ultra-performance liquid chromatography tandem mass spectrometry: Presentation of a dietary AGE database

Scheijen, J. L. J. M., Clevers, E., Engelen, L., Dagnelie, P. C., Brouns, F., Stehouwer, C. D. A., & Schalkwijk, C. G. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2015.06.049 · Cited by 343 · see citing works

Alzheimer's disease as type 3 diabetes: common pathophysiological mechanisms between Alzheimer's disease and type 2 diabetes

Michailidis, M., Moraitou, D., Tata, D. A., Kalinderi, K., Papamitsou, T., & Papaliagkas, V. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052687 · Cited by 330 · see citing works

The role of advanced glycation end-products in the development of coronary artery disease in patients with and without diabetes mellitus: a review

Fishman, S. L., Sonmez, H., Basman, C., Singh, V., & Poretsky, L. (2018) · Molecular Medicine · doi:10.1186/s10020-018-0060-3 · Cited by 330 · see citing works

AGE restriction in diabetes mellitus: a paradigm shift

Vlassara, H., & Striker, G. E. (2011) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2011.74 · Cited by 277 · see citing works

Diabetic Retinopathy and the Risk of Coronary Heart Disease

Cheung, N., Wang, J. J., Klein, R., Couper, D. J., Sharrett, A. R., & Wong, T. Y. (2007) · Diabetes Care · doi:10.2337/dc07-0264 · Cited by 267 · see citing works

Anti-Inflammatory Nutrients and Obesity-Associated Metabolic-Inflammation: State of the Art and Future Direction

Grosso, G., Laudisio, D., Frias-Toral, E., Barrea, L., Muscogiuri, G., Savastano, S., & Colao, A. (2022) · Nutrients · doi:10.3390/nu14061137 · Cited by 255 · see citing works

Clearance mechanisms of Alzheimer's amyloid-β peptide: implications for therapeutic design and diagnostic tests

Bates, K. A., Verdile, G., Li, Q.-X., Ames, D., Hudson, P., Masters, C. L., & Martins, R. N. (2009) · Molecular Psychiatry · doi:10.1038/mp.2008.96 · Cited by 247 · see citing works

Sugar sweetened beverages consumption and risk of coronary heart disease: A meta-analysis of prospective studies

Huang, C., Huang, J., Tian, Y., Yang, X., & Gu, D. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.01.037 · Cited by 198 · see citing works

Development and Progression of Non-Alcoholic Fatty Liver Disease: The Role of Advanced Glycation End Products

Fernando, D. H., Forbes, J. M., Angus, P. W., & Herath, C. B. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20205037 · Cited by 184 · see citing works

Hyperglycemia and Endothelial Dysfunction in Atherosclerosis: Lessons from Type 1 Diabetes

Funk, S. D., Yurdagul, A., & Orr, A. W. (2012) · International Journal of Vascular Medicine · doi:10.1155/2012/569654 · Cited by 176 · see citing works

The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases

Senatus, L. M., & Schmidt, A. M. (2017) · Frontiers in Genetics · doi:10.3389/fgene.2017.00187 · Cited by 167 · see citing works

Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction

Szabo, C. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2008.00086.x · Cited by 165 · see citing works

Advanced glycation end products mediated cellular and molecular events in the pathology of diabetic nephropathy

Kumar Pasupulati, A., Chitra, P. S., & Reddy, G. B. (2016) · Biomolecular Concepts · doi:10.1515/bmc-2016-0021 · Cited by 163 · see citing works

Inhibition of Protein Glycation by Extracts of Culinary Herbs and Spices

Dearlove, R. P., Greenspan, P., Hartle, D. K., Swanson, R. B., & Hargrove, J. L. (2008) · Journal of Medicinal Food · doi:10.1089/jmf.2007.536 · Cited by 157 · see citing works

Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats

Thompson, R. F., Fazzari, M. J., Niu, H., Barzilai, N., Simmons, R. A., & Greally, J. M. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.095133 · Cited by 154 · see citing works

Dietary Glycemic Index, Glycemic Load, and Risk of Coronary Heart Disease, Stroke, and Stroke Mortality: A Systematic Review with Meta-Analysis

Fan, J., Song, Y., Wang, Y., Hui, R., & Zhang, W. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052182 · Cited by 148 · see citing works

Role of Cellular Senescence in Type II Diabetes

Narasimhan, A., Flores, R. R., Robbins, P. D., & Niedernhofer, L. J. (2021) · Endocrinology · doi:10.1210/endocr/bqab136 · Cited by 133 · see citing works

Advanced glycation end products increase endothelial permeability through the RAGE/Rho signaling pathway

Hirose, A., Tanikawa, T., Mori, H., Okada, Y., & Tanaka, Y. (2010) · FEBS Letters · doi:10.1016/j.febslet.2009.11.082 · Cited by 129 · see citing works

Cognitive dysfunction: a growing link between diabetes and Alzheimer’s disease

Jash, K., Gondaliya, P., Kirave, P., Kulkarni, B., Sunkaria, A., & Kalia, K. (2020) · Drug Development Research · doi:10.1002/ddr.21579 · Cited by 119 · see citing works

Comparison of patients with heart failure and preserved left ventricular ejection fraction among those with versus without diabetes mellitus

Aguilar, D., Deswal, A., Ramasubbu, K., Mann, D. L., & Bozkurt, B. (2010) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.09.041 · Cited by 96 · see citing works

Environmental pollution and the risk of developing metabolic disorders: obesity and diabetes

Khalil, W. J., Akeblersane, M., Khan, A. S., Moin, A. S. M., & Butler, A. E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24108870 · Cited by 95 · see citing works

Type 2 diabetes, related conditions, in relation and dementia: An opportunity for prevention?

Luchsinger, J. A. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-091687 · Cited by 91 · see citing works

Hemoglobin Glycation Index Is Associated With Cardiovascular Diseases in People With Impaired Glucose Metabolism

Ahn, C. H., Min, S. H., Lee, D.-H., Oh, T. J., Kim, K. M., Moon, J. H., Choi, S. H., Park, K. S., Jang, H. C., Ha, J., et al. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-00191 · Cited by 91 · see citing works

Dietary glycotoxins exacerbate progression of experimental fatty liver disease

Leung, C., Herath, C. B., Jia, Z., Goodwin, M., Mak, K. Y., Watt, M. J., Forbes, J. M., & Angus, P. W. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2013.11.033 · Cited by 88 · see citing works

Kidney, heart and brain: three organs targeted by ageing and glycation

Frimat, M., Daroux, M., Litke, R., Nevière, R., Tessier, F. J., & Boulanger, E. (2017) · Clinical Science · doi:10.1042/cs20160823 · Cited by 88 · see citing works

Advanced glycation end products promote hepatosteatosis by interfering with SCAP-SREBP pathway in fructose-drinking mice

Mastrocola, R., Collino, M., Rogazzo, M., Medana, C., Nigro, D., Boccuzzi, G., & Aragno, M. (2013) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00450.2012 · Cited by 63 · see citing works

Bioactive compounds isolated from apple, tea, and ginger protect against dicarbonyl induced stress in cultured human retinal epithelial cells

Sampath, C., Zhu, Y., Sang, S., & Ahmedna, M. (2016) · Phytomedicine · doi:10.1016/j.phymed.2015.12.013 · Cited by 48 · see citing works

Phycocyanin prevents methylglyoxal-induced mitochondrial-dependent apoptosis in INS-1 cells by Nrf2

Gao, Y., Liu, C., Wan, G., Wang, X., Cheng, X., & Ou, Y. (2016) · Food & Function · doi:10.1039/c5fo01548k · Cited by 43 · see citing works

Quantification of protein glycation using vibrational spectroscopy

McAvan, B. S., France, A. P., Bellina, B., Barran, P. E., Goodacre, R., & Doig, A. J. (2020) · The Analyst · doi:10.1039/c9an02318f · Cited by 35 · see citing works

Aging skin: The role of diet: Facts and controversies

Draelos, Z. D. (2013) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2013.05.005 · Cited by 33 · see citing works

Activation of Macrophages and Microglia by Interferon-γ and Lipopolysaccharide Increases Methylglyoxal Production: A New Mechanism in the Development of Vascular Complications and Cognitive Decline in Type 2 Diabetes Mellitus?

Dhananjayan, K., Gunawardena, D., Hearn, N., Sonntag, T., Moran, C., Gyengesi, E., Srikanth, V., & Münch, G. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-161152 · Cited by 24 · see citing works

Elevated endogenous secretory receptor for advanced glycation end products (esRAGE) levels are associated with circulating soluble RAGE levels in diabetic children

Saito, R., Araki, S., Yamamoto, Y., & Kusuhara, K. (2017) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2016-0262 · Cited by 8 · see citing works

The Relationship Between the Continuum of Elevated Adiposity, Hyperinsulinemia, and Type 2 Diabetes and Late-onset Alzheimer’s Disease: An Epidemiological Perspective

Luchsinger, J. A. (2010) · Research and Perspectives in Alzheimer's Disease · doi:10.1007/978-3-642-04300-0_7 · Cited by 3 · see citing works

[AGEs and RAGE - advanced glycation end-products and their receptor in questions and answers].

Kalousová, M., & Zima, T. (2014) · PubMed · Cited by 4 · see citing works

ADVANCED GLYCATION END PRODUCTS AND THEIR RECEPTORS IN CARDIOVASCULAR DISEASES

Шевцова, А. И., & Ткаченко, В. А. (2019) · Journal of the Grodno State Medical University · doi:10.25298/2221-8785-2019-17-1-11-16 · Cited by 5 · see citing works

Role of Receptor for Advanced Glycation End Products (RAGE) and Its Ligands in Cancer Risk

Yamagishi, S., Matsui, T., & Fukami, K. (2014) · Rejuvenation Research · doi:10.1089/rej.2014.1625 · Cited by 71 · see citing works

The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs

Xue, J., Ray, R., Singer, D., Böhme, D., Burz, D. S., Rai, V., Hoffmann, R., & Shekhtman, A. (2014) · Biochemistry · doi:10.1021/bi500046t · Cited by 186 · see citing works

The pathogenesis of receptor for advanced glycation end products in diabetic chronic complication

Da, Z. (1999) · Zhongguo bingli shengli zazhi