The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Ultrasound Lung Comets for the Differential Diagnosis of Acute Cardiogenic Dyspnoea: A Comparison with Natriuretic Peptides
Abstract
Background: Acute dyspnoea as a presenting symptom is a frequent diagnostic challenge for physicians. The main differential diagnosis is between dyspnoea of cardiac and non-cardiac origin. Natriuretic peptides have been shown to be useful in this setting. Ultrasound lung comets (ULCs) are a simple, echographic method which can be used to assess pulmonary congestion. Aim: To evaluate the accuracy of ULCs for predicting dyspnoea of cardiac origin compared to natriuretic peptides. Methods: We evaluated 149 patients admitted with acute dyspnoea. Chest sonography and NT-proBNP assessments were performed a maximum of 4 h apart and independently analyzed. ULCs were evaluated via cardiac probes placed on the anterior and lateral chest. Two independent physicians, blinded to ULCs and NT-proBNP findings, reviewed all the medical records to establish the aetiologic diagnosis of dyspnoea. Results: Cardiogenic dyspnoea was confirmed in 122 patients and ruled-out in 27 patients. The number of ULCs was significantly correlated to NT-proBNP values (r=.69, p<.0001). Receiver operating characteristic analysis, showed an area under the curve of .893 for ULCs and .978 (p=.001) for NT-proBNP, in predicting the cardiac origin of dyspnoea. Conclusions: In patients admitted with acute dyspnoea, pulmonary congestion, sonographically imaged as ULCs, is significantly correlated to NT-proBNP values. The accuracy of ULCs in predicting the cardiac origin of dyspnoea is high.
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The N-terminal Pro-BNP Investigation of Dyspnea in the Emergency department (PRIDE) study
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The Comet-tail Artifact: An Ultrasound Sign of Alveolar-Interstitial Syndrome
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Cited by
Roberts, E., Ludman, A. J., Dworzynski, K., Al-Mohammad, A., Cowie, M. R., McMurray, J. J. V., Mant, J., & on behalf of the NICE Guideline Development Group for Acute Heart Failure (2015) · BMJ · doi:10.1136/bmj.h910 · Cited by 427
(2015) · doi:10.1002/ejhf.289 · Cited by 417
Metadata
- Authors
- Gargani, L., Frassi, F., Soldati, G., Tesorio, P., Gheorghiade, M., & Picano, E.
- Venue
- European Journal of Heart Failure
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-01-01
- Volume
- 10
- Issue
- 1
- Pages
- 70-77
- ISSN
- 1388-9842 (ISSN-L)
- 1879-0844
- OpenAlex
- W1985196874
- Cited by
- 272
- References
- 32
- FWCI
- 7.17
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gargani, L., Frassi, F., Soldati, G., Tesorio, P., Gheorghiade, M., & Picano, E. (2008). Ultrasound Lung Comets for the Differential Diagnosis of Acute Cardiogenic Dyspnoea: A Comparison with Natriuretic Peptides. European Journal of Heart Failure. https://doi.org/10.1016/j.ejheart.2007.10.009
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