The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
A review on recent developments of indole-containing antiviral agents
Open accessAbstract
Indole represents one of the most important privileged scaffolds in drug discovery. Indole derivatives have the unique property of mimicking the structure of peptides and to bind reversibly to enzymes, which provide tremendous opportunities to discover novel drugs with different modes of action. There are seven indole-containing commercial drugs in the Top-200 Best Selling Drugs by US Retail Sales in 2012. There are also an amazing number of approved indole-containing drugs in the market as well as compounds currently going through different clinical phases or registration statuses. This review focused on the recent development of indole derivatives as antiviral agents with the following objectives: 1) To present one of the most comprehensive listings of indole antiviral agents, drugs on market or compounds in clinical trials; 2) To focus on recent developments of indole compounds (including natural products) and their antiviral activities, summarize the structure property, hoping to inspire new and even more creative approaches; 3) To offer perspectives on how indole scaffolds as a privileged structure might be exploited in the future.
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Cites
Faulkner, D. J. (1990) · Natural Product Reports · doi:10.1039/np9900700269 · Cited by 4,866
Privileged scaffolds for library design and drug discovery
Welsch, M. E., Snyder, S. A., & Stockwell, B. R. (2010) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2010.02.018 · Cited by 1,509
Evans, B. E., Rittle, K. E., Bock, M. G., DiPardo, R. M., Freidinger, R. M., Whitter, W. L., Lundell, G. F., Veber, D. F., Anderson, P. S., Chang, R. S. L., et al. (1988) · Journal of Medicinal Chemistry · doi:10.1021/jm00120a002 · Cited by 1,456
The exploration of macrocycles for drug discovery — an underexploited structural class
Driggers, E. M., Hale, S. P., Lee, J., & Terrett, N. K. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2590 · Cited by 1,370
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis
HIGDON, J., DELAGE, B., WILLIAMS, D., & DASHWOOD, R. (2007) · Pharmacological Research · doi:10.1016/j.phrs.2007.01.009 · Cited by 1,039
Won, C., Shen, X., Mashiguchi, K., Zheng, Z., Dai, X., Cheng, Y., Kasahara, H., Kamiya, Y., Chory, J., & Zhao, Y. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1108436108 · Cited by 641
From Nature to Drug Discovery: The Indole Scaffold as a ‘Privileged Structure’
de Sa Alves, F., Barreiro, E., & Manssour Fraga, C. (2009) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955709788452649 · Cited by 604
Simple indole alkaloids and those with a non-rearranged monoterpenoid unit
Somei, M., & Yamada, F. (2005) · Natural Product Reports · doi:10.1039/b316241a · Cited by 548
Simple indole alkaloids and those with a nonrearranged monoterpenoid unit
Higuchi, K., & Kawasaki, T. (2007) · Natural Product Reports · doi:10.1039/b516351j · Cited by 510
Goldgur, Y., Craigie, R., Cohen, G. H., Fujiwara, T., Yoshinaga, T., Fujishita, T., Sugimoto, H., Endo, T., Murai, H., & Davies, D. R. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13040 · Cited by 496
Metadata
- Authors
- Zhang, M.-Z., Chen, Q., & Yang, G.-F.
- Venue
- European Journal of Medicinal Chemistry
- Publisher
- Elsevier BV
- Published
- 2015-01
- Volume
- 89
- Pages
- 421-441
- ISSN
- 0223-5234 (ISSN-L)
- OpenAlex
- W2048608017
- Cited by
- 887
- References
- 82
- FWCI
- 16.19
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Zhang, M.-Z., Chen, Q., & Yang, G.-F. (2015). A review on recent developments of indole-containing antiviral agents. European Journal of Medicinal Chemistry. https://doi.org/10.1016/j.ejmech.2014.10.065
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
