Privileged scaffolds for library design and drug discovery

The evolving role of natural products in drug discovery

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Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery

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Drugs for bad bugs: confronting the challenges of antibacterial discovery

Payne, D. J., Gwynn, M. N., Holmes, D. J., & Pompliano, D. L. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2201 · Cited by 2,512 · see citing works

A Planning Strategy for Diversity‐Oriented Synthesis

Burke, M. D., & Schreiber, S. L. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200300626 · Cited by 1,493 · see citing works

Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

Evans, B., Rittle, K. E., Bock, M. G., DiPardo, R. M., Freidinger, R. M., Whitter, W. L., Lundell, G. F., Veber, D. F., Anderson, P., Chang, R. S. L., et al. (1988) · Journal of Medicinal Chemistry · doi:10.1021/jm00120a002 · Cited by 1,460 · see citing works

Exploiting Chemical Libraries, Structure, and Genomics in the Search for Kinase Inhibitors

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From Nature to Drug Discovery: The Indole Scaffold as a ‘Privileged Structure’

Alves, F. R. S., Barreiro, E. J., & Fraga, C. A. M. (2009) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955709788452649 · Cited by 606 · see citing works

Diversity-oriented synthesis: Exploring the intersections between chemistry and biology

Tan, D. S. (2005) · Nature Chemical Biology · doi:10.1038/nchembio0705-74 · Cited by 605 · see citing works

Privileged Structures: Applications in Drug Discovery

DeSimone, R., Currie, K., Mitchell, S. A., Darrow, J. W., & Pippin, D. A. (2004) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/1386207043328544 · Cited by 579 · see citing works

Towards the Optimal Screening Collection: A Synthesis Strategy

Nielsen, T. E., & Schreiber, S. L. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200703073 · Cited by 552 · see citing works

Exploring biology with small organic molecules

Stockwell, B. R. (2004) · Nature · doi:10.1038/nature03196 · Cited by 473 · see citing works

Chemical genetics: ligand-based discovery of gene function

Stockwell, B. R. (2000) · Nature Reviews Genetics · doi:10.1038/35038557 · Cited by 418 · see citing works

Bacterial symbionts: prospects for the sustainable production of invertebrate-derived pharmaceuticals.

Costantino, L., & Barlocco, D. (2006) · PubMed · Cited by 411 · see citing works

Privileged Molecules for Protein Binding Identified from NMR-Based Screening

Hajduk, P. J., Bures, M. G., Praestgaard, J., & Fesik, S. W. (2000) · Journal of Medicinal Chemistry · doi:10.1021/jm000164q · Cited by 353 · see citing works

Privileged Structures as Leads in Medicinal Chemistry

Costantino, L., & Barlocco, D. (2005) · Current Medicinal Chemistry · doi:10.2174/092986706775197999 · Cited by 331 · see citing works

Privileged Structures: A Useful Concept for the Rational Design of New Lead Drug Candidates

Duarte, C. D., Barreiro, E. J., & Fraga, C. A. M. (2007) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955707782331722 · Cited by 309 · see citing works

Scaffold Architecture and Pharmacophoric Properties of Natural Products and Trade Drugs: Application in the Design of Natural Product-Based Combinatorial Libraries

Lee, M., & Schneider, G. (2001) · Journal of Combinatorial Chemistry · doi:10.1021/cc000097l · Cited by 291 · see citing works

The Chemodiversity of Purine as a Constituent of Natural Products

Rosemeyer, H. (2004) · Chemistry & Biodiversity · doi:10.1002/cbdv.200490033 · Cited by 285 · see citing works

Rhodanine as a Privileged Scaffold in Drug Discovery

Tomašič, T., & Masic, L. (2009) · Current Medicinal Chemistry · doi:10.2174/092986709788186200 · Cited by 277 · see citing works

Natural Product-like Combinatorial Libraries Based on Privileged Structures. 2. Construction of a 10 000-Membered Benzopyran Library by Directed Split-and-Pool Chemistry Using NanoKans and Optical Encoding

Nicolaou, K. C., Pfefferkorn, J. A., Mitchell, H. J., Roecker, A. J., Barluenga, S., Cao, G., Affleck, R. L., & Lillig, J. (2000) · Journal of the American Chemical Society · doi:10.1021/ja002034c · Cited by 270 · see citing works

Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors

Chang, Y., Gray, N. S., Rosania, G. R., Sutherlin, D. P., Kwon, S., Norman, T., Sarohia, R., Leost, M., Meijer, L., & Schultz, P. G. (1999) · Chemistry & Biology · doi:10.1016/s1074-5521(99)80048-9 · Cited by 269 · see citing works

The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library.

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Identification of a Novel Small-Molecule Inhibitor of the Hypoxia-Inducible Factor 1 Pathway

Tan, C., de Noronha, R. G., Roecker, A. J., Pyrzyńska, B., Khwaja, F. W., Zhang, Z., Zhang, H., Teng, Q., Nicholson, A. C., Giannakakou, P., et al. (2005) · Cancer Research · doi:10.1158/0008-5472.605.65.2 · Cited by 225 · see citing works

Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries

Cordier, C., Morton, D., Murrison, S., Nelson, A. S., & O'Leary-Steele, C. (2008) · Natural Product Reports · doi:10.1039/b706296f · Cited by 215 · see citing works

Medicinal chemistry of target family-directed masterkeys

Müller, G. (2003) · Drug Discovery Today · doi:10.1016/s1359-6446(03)02781-8 · Cited by 208 · see citing works

Libraries from natural product-like scaffolds

Boldi, A. M. (2004) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2004.04.010 · Cited by 194 · see citing works

Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 2. Antiproliferative and Antitubulin Activities of Pyrano[3,2-c]pyridones and Pyrano[3,2-c]quinolones

Magedov, I. V., Manpadi, M., Ogasawara, M. A., Dhawan, A. S., Rogelj, S., slambrouck, S. V., Steelant, W. F. A., Evdokimov, N. M., Uglinskii, P. Y., Elias, E. M., et al. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm701499n · Cited by 173 · see citing works

Et 2 SBr⋅SbCl 5 Br: An Effective Reagent for Direct Bromonium‐Induced Polyene Cyclizations

Snyder, S. A., & Treitler, D. S. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200903834 · Cited by 164 · see citing works

2-Arylbenzothiazole as a Privileged Scaffold in Drug Discovery

Weekes, A. A., & Westwell, A. D. (2009) · Current Medicinal Chemistry · doi:10.2174/092986709788682137 · Cited by 151 · see citing works

Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents

Filho, J. M. D. S., Leite, A. C. L., Oliveira, B. G. D., Moreira, D. R. M., Lima, M. S., Soares, M. B. P., & Leite, L. F. C. C. (2009) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2009.07.068 · Cited by 100 · see citing works

Protein β-turn mimetics I. Design, synthesis, and evaluation in model cyclic peptides.

Ripka, W. C., Lucca, G. V. D., Bach, A., Pottorf, R. S., & Blaney, J. M. (1993) · Tetrahedron · doi:10.1016/s0040-4020(01)90217-0 · Cited by 98 · see citing works

Natural Compounds: Leads or Ideas? Bioinspired Molecules for Drug Discovery

Beghyn, T. B., Deprez-Poulain, R. F., Willand, N., Folléas, B., & Deprez, B. P. (2008) · Chemical Biology & Drug Design · doi:10.1111/j.1747-0285.2008.00673.x · Cited by 92 · see citing works

Fischer indole synthesis on a solid support

Hutchins, S. M., & Chapman, K. T. (1996) · Tetrahedron Letters · doi:10.1016/0040-4039(96)00997-5 · Cited by 90 · see citing works

Diversity-Oriented Synthesis of Privileged Benzopyranyl Heterocycles from s-cis-Enones

An, H., Eum, S., Koh, M., Lee, S. K., & Park, S. B. (2008) · The Journal of Organic Chemistry · doi:10.1021/jo702196f · Cited by 76 · see citing works

Discovery of Estrogen Sulfotransferase Inhibitors from a Purine Library Screen

Verdugo, D. E., Cancilla, M. T., Ge, X., Gray, N. S., Chang, Y., Schultz, P. G., Negishi, M., Leary, J. A., & Bertozzi, C. R. (2001) · Journal of Medicinal Chemistry · doi:10.1021/jm010171u · Cited by 74 · see citing works

The principle of complementarity: chemical versus biological space

Haggarty, S. J. (2005) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2005.04.006 · Cited by 72 · see citing works

Combinatorial Chemistry with Laser Optical Encoding

Xiao, X., Zhao, C., Potash, H., & Nova, M. P. (1997) · Angewandte Chemie International Edition in English · doi:10.1002/anie.199707801 · Cited by 58 · see citing works

2-Aryl indole NK1 receptor antagonists: optimisation of the 2-Aryl ring and the indole nitrogen substituent

Dinnell, K., Chicchi, G. G., Dhar, M. J., Elliott, J. M., Hollingworth, G. J., Kurtz, M. M., Ridgill, M. P., Rycroft, W., Tsao, K.-L. C., Williams, A. R., et al. (2001) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(01)00183-4 · Cited by 58 · see citing works

Combinatorial synthesis of 3-(Amidoalkyl) and 3-(Aminoalkyl)-2-arylindole derivatives: discovery of potent ligands for a variety of G-protein coupled receptors

Willoughby, C. A., Hutchins, S. M., Rosauer, K. G., Dhar, M. J., Chapman, K. T., Chicchi, G. G., Sadowski, S. J., Weinberg, D. H., Patel, S. S., Malkowitz, L., et al. (2002) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(01)00665-5 · Cited by 44 · see citing works

Systematic Analysis of Public Domain Compound Potency Data Identifies Selective Molecular Scaffolds across Druggable Target Families

Hu, Y., Wassermann, A. M., Lounkine, E., & Bajorath, J. (2009) · Journal of Medicinal Chemistry · doi:10.1021/jm9014229 · Cited by 41 · see citing works

Chemical Proteomics-Based Drug Design: Target and Antitarget Fishing with a Catechol−Rhodanine Privileged Scaffold for NAD(P)(H) Binding Proteins

Ge, X., Wakim, B. T., & Sem, D. S. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm8002284 · Cited by 36 · see citing works

Synthesis and Stereochemical Structure−Activity Relationships of 1,3-Dioxoperhydropyrido[1,2-c]pyrimidine Derivatives: Potent and Selective Cholecystokinin-A Receptor Antagonists

Martín‐Martinez, M., Bartolomé-Nebreda, J. M., Gomez-Monterrey, I. M., González‐Muñiz, R., García‐López, M. T., Ballaz, S., Barber, A., Fortuño, A., Río, J. D., & Herranz, R. (1997) · Journal of Medicinal Chemistry · doi:10.1021/jm9703247 · Cited by 36 · see citing works

The proapoptotic benzodiazepine Bz-423 affects the growth and survival of malignant B cells.

Boitano, A. E., Ellman, J. A., Glick, G. D., & Opipari, A. W. (2003) · PubMed · Cited by 32 · see citing works

Discovery of Indoline-Based, Natural-Product-like Compounds as Probes of Focal Adhesion Kinase Signaling Pathways

Poondra, R. R., Kumar, N., Bijian, K., Prakesch, M. A., Campágna‐Slater, V., Reayi, A., Reddy, P. T., Choudhry, A., Barnes, M. L., Leek, D. M., et al. (2009) · Journal of Combinatorial Chemistry · doi:10.1021/cc8001525 · Cited by 21 · see citing works

Combinatorial Library Synthesis and Biological Evaluation of Pyrazolo[4,3‐e][1,4]diazepine as a Potential Privileged Structure

Lee, J., & Kim, Y. (2009) · ChemMedChem · doi:10.1002/cmdc.200800453 · Cited by 16 · see citing works

Lasercodierung in der kombinatorischen Chemie

Xiao, X., Zhao, C., Potash, H., & Nova, M. P. (1997) · Angewandte Chemie · doi:10.1002/ange.19971090729 · Cited by 8 · see citing works

ChemInform Abstract: 2‐Aryl Indole NK1 Receptor Antagonists: Optimization of the 2‐Aryl Ring and the Indole Nitrogen Substituent.

Dinnell, K., & al., E. A. E. (2001) · ChemInform · doi:10.1002/chin.200133127 · Cited by 3 · see citing works

Untitled work

(2002) · doi:10.1002/1521-3773(20020816)41:16

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

Dixon, S. J., Patel, D. N., Welsch, M., Skouta, R., Lee, E. D., Hayano, M., Thomas, A. G., Gleason, C. E., Tatonetti, N. P., Slusher, B. S., et al. (2014) · eLife · doi:10.7554/elife.02523 · Cited by 2,088 · see citing works

Click Chemistry for Drug Development and Diverse Chemical–Biology Applications

Prakasam, T., Matosiuk, D., & Jóźwiak, K. (2013) · Chemical Reviews · doi:10.1021/cr200409f · Cited by 1,907 · see citing works

Chalcone: A Privileged Structure in Medicinal Chemistry

Zhuang, C., Zhang, W., Sheng, C., Zhang, W., Xing, C., & Miao, Z. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00020 · Cited by 1,486 · see citing works

Deep reinforcement learning for de novo drug design

Popova, M., Isayev, O., & Tropsha, A. (2018) · Science Advances · doi:10.1126/sciadv.aap7885 · Cited by 1,379 · see citing works

Single-electron transmetalation in organoboron cross-coupling by photoredox/nickel dual catalysis

Tellis, J. C., Primer, D. N., & Molander, G. A. (2014) · Science · doi:10.1126/science.1253647 · Cited by 1,286 · see citing works

A review on recent developments of indole-containing antiviral agents

Zhang, M., Chen, Q., & Yang, G. (2014) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2014.10.065 · Cited by 892 · see citing works

Medicinal attributes of 1,2,3-triazoles: Current developments

Dheer, D., Singh, V., & Shankar, R. (2017) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2017.01.010 · Cited by 884 · see citing works

Tetrazoles via Multicomponent Reactions

Neochoritis, C. G., Zhao, T. K., & Dömling, A. S. S. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00564 · Cited by 607 · see citing works

Recent developments in solvent-free multicomponent reactions: a perfect synergy for eco-compatible organic synthesis

Singh, M. S., & Chowdhury, S. (2012) · RSC Advances · doi:10.1039/c2ra01056a · Cited by 506 · see citing works

When Light Meets Nitrogen-Centered Radicals: From Reagents to Catalysts

Yu, X., Zhao, Q., Chen, J., Xiao, W., & Chen, J. (2020) · Accounts of Chemical Research · doi:10.1021/acs.accounts.0c00090 · Cited by 506 · see citing works

Rings in Clinical Trials and Drugs: Present and Future

Shearer, J., Castro, J. L., Lawson, A. D. G., MacCoss, M., & Taylor, R. D. (2022) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.2c00473 · Cited by 491 · see citing works

Ligand and Target Discovery by Fragment-Based Screening in Human Cells

Parker, C. G., Galmozzi, A., Wang, Y., Correia, B. E., Sasaki, K., Joslyn, C. M., Kim, A. S., Cavallaro, C. L., Lawrence, R. M., Johnson, S. R., et al. (2017) · Cell · doi:10.1016/j.cell.2016.12.029 · Cited by 439 · see citing works

Recent advances in spirocyclization of indole derivatives

Bariwal, J. B., Voskressensky, L. G., & der Eycken, E. V. V. (2018) · Chemical Society Reviews · doi:10.1039/c7cs00508c · Cited by 426 · see citing works

Visible‐Light‐Mediated Generation of Nitrogen‐Centered Radicals: Metal‐Free Hydroimination and Iminohydroxylation Cyclization Reactions

Davies, J., Booth, S. G., Labouille, S., Dryfe, R. A. W., & Leonori, D. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201507641 · Cited by 423 · see citing works

Iridium-Catalyzed C–H Borylation of Heteroarenes: Scope, Regioselectivity, Application to Late-Stage Functionalization, and Mechanism

Larsen, M. A., & Hartwig, J. F. (2014) · Journal of the American Chemical Society · doi:10.1021/ja412563e · Cited by 418 · see citing works

Asymmetric organocatalysis: an enabling technology for medicinal chemistry

Han, B., He, X., Liu, Y., He, G., Peng, C. Y., & Li, J. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00196a · Cited by 405 · see citing works

Synergistic Dual Transition Metal Catalysis

Kim, U. B., Jung, D. J., Jeon, H. J., Rathwell, K., & Lee, S. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00245 · Cited by 402 · see citing works

Discovery and Characterization of Sulfoxaflor, a Novel Insecticide Targeting Sap-Feeding Pests

Zhu, Y., Loso, M. R., Watson, G. B., Sparks, T. C., Rogers, R. B., Huang, J. X., Gerwick, B. C., Babcock, J. M., Kelley, D. R., Hegde, V. B., et al. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf102765x · Cited by 382 · see citing works

Electrochemically Driven, Ni-Catalyzed Aryl Amination: Scope, Mechanism, and Applications

Kawamata, Y., Vantourout, J. C., Hickey, D. P., Bai, P., Chen, L., Hou, Q., Qiao, W., Barman, K., Edwards, M. A., Garrido‐Castro, A. F., et al. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.9b01886 · Cited by 375 · see citing works

Liquid‐Assisted Grinding Mechanochemistry in the Synthesis of Pharmaceuticals

Ying, P., Yu, J., & Su, W. (2021) · Advanced Synthesis & Catalysis · doi:10.1002/adsc.202001245 · Cited by 370 · see citing works

The Open Access Malaria Box: A Drug Discovery Catalyst for Neglected Diseases

Spangenberg, T., Burrows, J. N., Kowalczyk, P., McDonald, S., Wells, T. N. C., & Willis, P. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062906 · Cited by 339 · see citing works

Synthesis of Spirocyclic Indolenines

James, M. J., O’Brien, P., Taylor, R. J. K., & Unsworth, W. P. (2015) · Chemistry - A European Journal · doi:10.1002/chem.201503835 · Cited by 339 · see citing works

Visible-Light-Mediated Synthesis of Amidyl Radicals: Transition-Metal-Free Hydroamination and N -Arylation Reactions

Davies, J., Svejstrup, T. D., Reina, D. F., Sheikh, N. S., & Leonori, D. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b04920 · Cited by 334 · see citing works

Photoredox-mediated Minisci C–H alkylation of N-heteroarenes using boronic acids and hypervalent iodine

Li, G., Morales-Rivera, C. A., Wang, Y., Gao, F., He, G., Liu, P., & Chen, G. (2016) · Chemical Science · doi:10.1039/c6sc02653b · Cited by 331 · see citing works

Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters

Xu, P., Yu, J., Chen, C., Cao, Z., Zhou, F., & Zhou, J. E. (2019) · ACS Catalysis · doi:10.1021/acscatal.8b03694 · Cited by 325 · see citing works

Single-Electron Transmetalation: An Enabling Technology for Secondary Alkylboron Cross-Coupling

Primer, D. N., Karakaya, İ., Tellis, J. C., & Molander, G. A. (2015) · Journal of the American Chemical Society · doi:10.1021/ja512946e · Cited by 320 · see citing works

Iminosugars as Therapeutic Agents: Recent Advances and Promising Trends

Nash, R. J., Kato, A., Yu, C.-Y., & Fleet, G. W. J. (2011) · Future Medicinal Chemistry · doi:10.4155/fmc.11.117 · Cited by 302 · see citing works

Recent Developments in Ruthenium-Catalyzed C–H Arylation: Array of Mechanistic Manifolds

Nareddy, P. R., Jordan, F., & Szostak, M. (2017) · ACS Catalysis · doi:10.1021/acscatal.7b01645 · Cited by 291 · see citing works

Base-Free Photoredox/Nickel Dual-Catalytic Cross-Coupling of Ammonium Alkylsilicates

Jouffroy, M., Primer, D. N., & Molander, G. A. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b10963 · Cited by 288 · see citing works

Metal-free C–H alkylation of heteroarenes with alkyltrifluoroborates: a general protocol for 1°, 2° and 3° alkylation

Matsui, J. K., Primer, D. N., & Molander, G. A. (2017) · Chemical Science · doi:10.1039/c7sc00283a · Cited by 284 · see citing works

Nicotinic Acetylcholine Receptor Agonists: A Milestone for Modern Crop Protection

Jeschke, P., Nauen, R., & Beck, M. E. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201302550 · Cited by 260 · see citing works

Recent advances in catalyst-free photochemical reactions via electron-donor-acceptor (EDA) complex process

Yuan, Y., Majumder, S., Yang, M., & Guo, S. (2019) · Tetrahedron Letters · doi:10.1016/j.tetlet.2019.151506 · Cited by 258 · see citing works

Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets

Davies, D. R., Gelinas, A. D., Zhang, C., Rohloff, J. C., Carter, J. D., O’Connell, D., Waugh, S. M., Wolk, S. K., Mayfield, W. S., Burgin, A. B., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1213933109 · Cited by 257 · see citing works

Late-Stage C–H Alkylation of Heterocycles and 1,4-Quinones via Oxidative Homolysis of 1,4-Dihydropyridines

Gutiérrez‐Bonet, Á., Remeur, C., Matsui, J. K., & Molander, G. A. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b05899 · Cited by 255 · see citing works

An overview of quinoline as a privileged scaffold in cancer drug discovery

Musioł, R. (2017) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2017.1319357 · Cited by 249 · see citing works

Natural product derived privileged scaffolds in drug discovery

Davison, E. K., & Brimble, M. A. (2019) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2018.12.007 · Cited by 249 · see citing works

Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology <i>in vivo</i> and <i>in vitro</i>

Moses, T., Pollier, J., Thevelein, J. M., & Goossens, A. (2013) · New Phytologist · doi:10.1111/nph.12325 · Cited by 245 · see citing works

Palladium‐Catalyzed Synthesis of Benzofurans and Coumarins from Phenols and Olefins

Sharma, U. K., Naveen, T., Maji, A., Manna, S., & Maiti, D. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201305326 · Cited by 224 · see citing works

Heteroatom–Heteroatom Bond Formation in Natural Product Biosynthesis

Waldman, A. J., Ng, T. L., Wang, P., & Balskus, E. P. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00621 · Cited by 225 · see citing works

Natural products as starting points for the synthesis of complex and diverse compounds

Morrison, K. C., & Hergenrother, P. J. (2013) · Natural Product Reports · doi:10.1039/c3np70063a · Cited by 219 · see citing works

Redox-Neutral Indole Annulation Cascades

Haibach, M. C., Deb, I., De, C. K., & Seidel, D. (2011) · Journal of the American Chemical Society · doi:10.1021/ja110713k · Cited by 211 · see citing works

A Versatile Approach to Ullmann C–N Couplings at Room Temperature: New Families of Nucleophiles and Electrophiles for Photoinduced, Copper-Catalyzed Processes

Ziegler, D. T., Choi, J., Muñoz‐Molina, J. M., Bissember, A. C., Peters, J. C., & Fu, G. C. (2013) · Journal of the American Chemical Society · doi:10.1021/ja4060806 · Cited by 202 · see citing works

Deaminative Reductive Arylation Enabled by Nickel/Photoredox Dual Catalysis

Yi, J., Badir, S. O., Kammer, L. M., Ribagorda, M., & Molander, G. A. (2019) · Organic Letters · doi:10.1021/acs.orglett.9b01097 · Cited by 201 · see citing works

DCAF11 Supports Targeted Protein Degradation by Electrophilic Proteolysis-Targeting Chimeras

Zhang, X., Luukkonen, L. M., Eissler, C. L., Crowley, V. M., Yamashita, Y., Schafroth, M. A., Kikuchi, S., Weinstein, D. S., Symons, K. T., Nordin, B. E., et al. (2021) · Journal of the American Chemical Society · doi:10.1021/jacs.1c00990 · Cited by 199 · see citing works

Mild Rhodium(III)‐Catalyzed Cyclization of Amides with α,β‐Unsaturated Aldehydes and Ketones to Azepinones: Application to the Synthesis of the Homoprotoberberine Framework

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5-Ene-4-thiazolidinones – An efficient tool in medicinal chemistry

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