Design and discovery of boronic acid drugs

Palladium(0)-Catalyzed Cross-Coupling Reaction of Alkoxydiboron with Haloarenes: A Direct Procedure for Arylboronic Esters

Ishiyama, T., Murata, M., & Miyaura, N. (1995) · The Journal of Organic Chemistry · doi:10.1021/jo00128a024 · Cited by 1,603 · see citing works

Boronic Acids

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Synthesis and Applications of Boronic Acid-Containing Polymers: From Materials to Medicine

Brooks, W. L. A., & Sumerlin, B. S. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00300 · Cited by 981 · see citing works

Generation of a Set of Simple, Interpretable ADMET Rules of Thumb

Gleeson, M. P. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm701122q · Cited by 973 · see citing works

Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives

Chen, D., Frezza, M., Schmitt, S. M., Kanwar, J., & Dou, Q. P. (2011) · Current Cancer Drug Targets · doi:10.2174/156800911794519752 · Cited by 796 · see citing works

The development of proteasome inhibitors as anticancer drugs

Adams, J. (2004) · Cancer Cell · doi:10.1016/s1535-6108(04)00120-5 · Cited by 778 · see citing works

Photoinduced decarboxylative borylation of carboxylic acids

Fawcett, A., Pradeilles, J. A., Wang, Y., et al. (2017) · Science · doi:10.1126/science.aan3679 · Cited by 705 · see citing works

Carboxylic Acid (Bio)Isosteres in Drug Design

Ballatore, C., Huryn, D. M., & Smith, A. B. (2013) · ChemMedChem · doi:10.1002/cmdc.201200585 · Cited by 527 · see citing works

Boron delivery agents for neutron capture therapy of cancer

Barth, R. F., Mi, P., & Yang, W. (2018) · 癌症：英文版 · doi:10.1186/s40880-018-0299-7 · Cited by 478 · see citing works

Crystal Structure of the Boronic Acid-Based Proteasome Inhibitor Bortezomib in Complex with the Yeast 20S Proteasome

Groll, M., Berkers, C. R., Ploegh, H. L., & Ovaa, H. (2006) · Structure · doi:10.1016/j.str.2005.11.019 · Cited by 475 · see citing works

Boron in Plants: Deficiency and Toxicity

Camacho‐Cristóbal, J. J., Rexach, J., & González‐Fontes, A. (2008) · Journal of Integrative Plant Biology · doi:10.1111/j.1744-7909.2008.00742.x · Cited by 455 · see citing works

Boron Containing Compounds as Protease Inhibitors

Smoum, R., Rubinstein, A., Dembitsky, V. M., & Srebnik, M. (2012) · Chemical Reviews · doi:10.1021/cr608202m · Cited by 451 · see citing works

Discovery of a Cyclic Boronic Acid β-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases

Hecker, S. J., Reddy, K. R., Totrov, M. M., et al. (2015) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b00127 · Cited by 422 · see citing works

United States Food and Drug Administration Approval Summary: Bortezomib for the Treatment of Progressive Multiple Myeloma after One Prior Therapy

Kane, R. C., Farrell, A. T., Sridhara, R., & Pazdur, R. (2006) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-0170 · Cited by 343 · see citing works

Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

Liu, B., Trout, R. E. L., Chu, G., McGarry, D. G., Jackson, R. W., Hamrick, J. C., Daigle, D. M., Cusick, S. M., Pozzi, C., Luca, F. D., et al. (2019) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.9b01518 · Cited by 323 · see citing works

Covalent inhibitors design and discovery.

De Cesco, S., Kurian, J., Dufresne, C., Mittermaier, A. K., & Moitessier, N. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.06.019 · Cited by 315 · see citing works

Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis

Baker, S. J., Zhang, Y.-K., Akama, T., et al. (2006) · Journal of Medicinal Chemistry · doi:10.1021/jm0603724 · Cited by 314 · see citing works

Boronic acids as building blocks for the construction of therapeutically useful bioconjugates

António, J. P. M., Russo, R. L., Carvalho, C. P., Cal, P. M. S. D., & Góis, P. M. P. (2019) · Chemical Society Reviews · doi:10.1039/c9cs00184k · Cited by 307 · see citing works

The importance of boron in biological systems

Uluışık, İ., Karakaya, H. Ç., & Koç, A. (2017) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2017.10.008 · Cited by 294 · see citing works

Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

Jansen, K., Heirbaut, L., Verkerk, R. M., Cheng, J. D., Joossens, J., Cos, P., Maes, L. J. R. M., Lambeir, A., Meester, I. D., Augustyns, K., et al. (2014) · Journal of Medicinal Chemistry · doi:10.1021/jm500031w · Cited by 293 · see citing works

DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis

Okondo, M. C., Johnson, D. C., Sridharan, R., Go, E. B., Chui, A. J., Wang, M. S., Poplawski, S. E., Wu, W., Liu, Y., Lai, J. H.-S., et al. (2016) · Nature Chemical Biology · doi:10.1038/nchembio.2229 · Cited by 288 · see citing works

Boronic acid catalysis

Hall, D. G. (2019) · Chemical Society Reviews · doi:10.1039/c9cs00191c · Cited by 281 · see citing works

Covalent docking of large libraries for the discovery of chemical probes

London, N., Miller, R. M., Krishnan, S., Uchida, K., Irwin, J. J., Eidam, O., Gibold, L., Cimermančič, P., Bonnet, R., Shoichet, B. K., et al. (2014) · Nature Chemical Biology · doi:10.1038/nchembio.1666 · Cited by 274 · see citing works

A realistic appraisal of boron neutron capture therapy as a cancer treatment modality

Barth, R. F., Zhang, Z., & Liu, T. (2018) · 癌症：英文版 · doi:10.1186/s40880-018-0280-5 · Cited by 249 · see citing works

Natural and Synthetic Small Boron-Containing Molecules as Potential Inhibitors of Bacterial and Fungal Quorum Sensing

Dembitsky, V. M., Quntar, A. A. A. A., & Srebnik, M. (2010) · Chemical Reviews · doi:10.1021/cr100093b · Cited by 240 · see citing works

Boronate Probes as Diagnostic Tools for Real Time Monitoring of Peroxynitrite and Hydroperoxides

Zielonka, J., Sikora, A., Hardy, M., Joseph, J., Dranka, B. P., & Kalyanaraman, B. (2012) · Chemical Research in Toxicology · doi:10.1021/tx300164j · Cited by 238 · see citing works

The inhibition mechanism of human 20 S proteasomes enables next-generation inhibitor design

Schrader, J., Henneberg, F., Mata, R. A., Tittmann, K., Schneider, T. R., Stark, H., Bourenkov, G. P., & Chari, A. (2016) · Science · doi:10.1126/science.aaf8993 · Cited by 237 · see citing works

Asymmetric Copper-Catalyzed Synthesis of α-Amino Boronate Esters from N - tert -Butanesulfinyl Aldimines

Beenen, M. A., An, C., & Ellman, J. A. (2008) · Journal of the American Chemical Society · doi:10.1021/ja800829y · Cited by 231 · see citing works

Decarboxylative Borylation of Aliphatic Esters under Visible-Light Photoredox Conditions

Hu, D., Wang, L., & Li, P. (2017) · Organic Letters · doi:10.1021/acs.orglett.7b01181 · Cited by 229 · see citing works

Discovery and structure–activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis

Akama, T., Baker, S. J., Zhang, Y., et al. (2009) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2009.03.007 · Cited by 218 · see citing works

Docking Ligands into Flexible and Solvated Macromolecules. 1. Development and Validation of FITTED 1.0

Corbeil, C. R., Englebienne, P., & Moitessier, N. (2007) · Journal of Chemical Information and Modeling · doi:10.1021/ci6002637 · Cited by 215 · see citing works

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation

Albers, H. M. H. G., Dong, A., van Meeteren, L. A., Egan, D. A., Sunkara, M., van Tilburg, E. W., Schuurman, K. G., van Tellingen, O., Morris, A. J., Smyth, S. S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001529107 · Cited by 207 · see citing works

Over the counter (OTC) artificial tear drops for dry eye syndrome

Pucker, A. D., Ng, S. M., & Nichols, J. J. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009729.pub2 · Cited by 202 · see citing works

PT-100, a Small Molecule Dipeptidyl Peptidase Inhibitor, Has Potent Antitumor Effects and Augments Antibody-Mediated Cytotoxicity via a Novel Immune Mechanism

Adams, S., Miller, G. T., Jesson, M. I., Watanabe, T., Jones, B. N., & Wallner, B. P. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-0447 · Cited by 202 · see citing works

Aldehyde toxicity and metabolism: the role of aldehyde dehydrogenases in detoxification, drug resistance and carcinogenesis

Laskar, A. A., & Younus, H. (2018) · Drug Metabolism Reviews · doi:10.1080/03602532.2018.1555587 · Cited by 202 · see citing works

Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome

Okondo, M. C., Rao, S. D., Taabazuing, C. Y., Chui, A. J., Poplawski, S. E., Johnson, D. C., & Bachovchin, D. A. (2018) · Cell chemical biology · doi:10.1016/j.chembiol.2017.12.013 · Cited by 198 · see citing works

The use of phosphate bioisosteres in medicinal chemistry and chemical biology

Elliott, T. S., Slowey, A., Ye, Y., & Conway, S. J. (2012) · MedChemComm · doi:10.1039/c2md20079a · Cited by 196 · see citing works

Acidic pH and High-H2O2 Dual Tumor Microenvironment-Responsive Nanocatalytic Graphene Oxide for Cancer Selective Therapy and Recognition

Lin, B., Chen, H., Liang, D., et al. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b22487 · Cited by 176 · see citing works

Selective Monosaccharide Transport through Lipid Bilayers Using Boronic Acid Carriers

Westmark, P. R., Gardiner, S. J., & Smith, B. D. (1996) · Journal of the American Chemical Society · doi:10.1021/ja961264h · Cited by 171 · see citing works

Ixazomib: First Global Approval

Shirley, M. (2016) · Drugs · doi:10.1007/s40265-016-0548-5 · Cited by 170 · see citing works

Inhibition of dipeptidyl aminopeptidase IV (DP-IV) by Xaa-boroPro dipeptides and use of these inhibitors to examine the role of DP-IV in T-cell function.

Flentke, G. R., Munoz, E., Huber, B. T., et al. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.4.1556 · Cited by 169 · see citing works

Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656)

Li, X., Hernandez, V. S., Rock, F. L., et al. (2017) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b00631 · Cited by 167 · see citing works

The inhibition of class C β -lactamases by boronic acids

Beesley, T. J., Gascoyne, N., Knott-Hunziker, V., Petursson, S., Waley, S. G., Jaurin, B., & Grundström, T. (1983) · Biochemical Journal · doi:10.1042/bj2090229 · Cited by 159 · see citing works

One-Pot Synthesis of Arylboronic Acids and Aryl Trifluoroborates by Ir-Catalyzed Borylation of Arenes

Murphy, J. M., Tzschucke, C. C., & Hartwig, J. F. (2007) · Organic Letters · doi:10.1021/ol062903o · Cited by 157 · see citing works

Cu-Catalyzed Decarboxylative Borylation

Wang, J., Shang, M., Lundberg, H., Feu, K. S., Hecker, S. J., Qin, T., Blackmond, D. G., & Baran, P. S. (2018) · ACS Catalysis · doi:10.1021/acscatal.8b02928 · Cited by 156 · see citing works

Peptide–Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology

Nitsche, C., Zhang, L., Weigel, L. F., Schilz, J., Graf, D., Bartenschlager, R. F. W., Hilgenfeld, R., & Klein, C. D. P. (2016) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6b01021 · Cited by 155 · see citing works

Deprotection of pinacolyl boronate esters via hydrolysis of intermediate potassium trifluoroborates

Yuen, A. K. L., & Hutton, C. A. (2005) · Tetrahedron Letters · doi:10.1016/j.tetlet.2005.09.101 · Cited by 154 · see citing works

Natural occurrence of boron-containing compounds in plants, algae and microorganisms

Dembitsky, V. M., Smoum, R., Quntar, A. A. A. A., Ali, H. A., Pergament, I., & Srebnik, M. (2002) · Plant Science · doi:10.1016/s0168-9452(02)00174-7 · Cited by 139 · see citing works

Synthesis of biologically active boron-containing compounds

Yang, F., Zhu, M., Zhang, J., & Zhou, H. (2017) · MedChemComm · doi:10.1039/c7md00552k · Cited by 133 · see citing works

Clinical and veterinary trypanocidal benzoxaboroles target CPSF3

Wall, R. J., Rico, E., Lukač, I., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1807915115 · Cited by 131 · see citing works

Spotlight on ixazomib: potential in the treatment of multiple myeloma

Azab, A. K., Muz, B., Ghazarian, R., Ou, M., Luderer, M. J., & Kusdono, H. D. (2016) · Drug Design Development and Therapy · doi:10.2147/dddt.s93602 · Cited by 130 · see citing works

Boron and nucleic acid chemistries: merging the best of both worlds

Martin, A. R., Vasseur, J., & Smietana, M. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60038f · Cited by 129 · see citing works

Prodrug strategies for targeted therapy triggered by reactive oxygen species

Cadahía, J. P., Previtali, V., Troelsen, N. S., & Clausen, M. H. (2019) · MedChemComm · doi:10.1039/c9md00169g · Cited by 119 · see citing works

Identification of Selective and Potent Inhibitors of Fibroblast Activation Protein and Prolyl Oligopeptidase

Poplawski, S. E., Lai, J. H.-S., Li, Y., Jin, Z., Liu, Y., Wu, W., Wu, Y. H., Zhou, Y., Sudmeier, J. L., Sanford, D. G., et al. (2013) · Journal of Medicinal Chemistry · doi:10.1021/jm400351a · Cited by 117 · see citing works

Identification of Borinic Esters as Inhibitors of Bacterial Cell Growth and Bacterial Methyltransferases, CcrM and MenH

Benkovic, S. J., Baker, S. J., Alley, M. R. K., et al. (2005) · Journal of Medicinal Chemistry · doi:10.1021/jm050676a · Cited by 116 · see citing works

Structure of aplasmomycin.

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Two efficient methods for the cleavage of pinanediol boronate esters yielding the free boronic acids

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Docking Ligands into Flexible and Solvated Macromolecules. 3. Impact of Input Ligand Conformation, Protein Flexibility, and Water Molecules on the Accuracy of Docking Programs

Corbeil, C. R., & Moitessier, N. (2009) · Journal of Chemical Information and Modeling · doi:10.1021/ci8004176 · Cited by 107 · see citing works

Docking for fragment inhibitors of AmpC β-lactamase

Teotico, D. G., Babaoglu, K., Rocklin, G. J., Ferreira, R. S., Giannetti, A. M., & Shoichet, B. K. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813029106 · Cited by 102 · see citing works

Mechanisms implicated in the effects of boron on wound healing

Nzietchueng, R., Dousset, B., Franck, P., et al. (2002) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/s0946-672x(02)80051-7 · Cited by 100 · see citing works

Asymmetric induction on β-boration of α,β-unsaturated compounds: an inexpensive approach

Lillo, V., Bonet, A., & Fernández, E. (2009) · Dalton Transactions · doi:10.1039/b819237e · Cited by 97 · see citing works

A comprehensive review of the FDA-approved labels of diabetes drugs: Indications, safety, and emerging cardiovascular safety data

Gourgari, E., Wilhelm, E. E., Hassanzadeh, H. R., Aroda, V. R., & Shoulson, I. (2017) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2017.08.005 · Cited by 97 · see citing works

Conversion of Alkyltrifluoroborates into Alkyldichloroboranes with Tetrachlorosilane in Coordinating Solvents

Kim, B. J., & Matteson, D. S. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200453690 · Cited by 94 · see citing works

Boromycin, an Anti-HIV Antibiotic

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Activity of biapenem (RPX2003) combined with the boronate -lactamase inhibitor RPX7009 against carbapenem-resistant Enterobacteriaceae

Livermore, D. M., & Mushtaq, S. (2013) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkt118 · Cited by 90 · see citing works

A histomorphometric study of alveolar bone modelling and remodelling in mice fed a boron-deficient diet

Gorustovich, A. A., Steimetz, T., Nielsen, F. H., et al. (2008) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2008.01.011 · Cited by 89 · see citing works

Fulvestrant-3 Boronic Acid (ZB716): An Orally Bioavailable Selective Estrogen Receptor Downregulator (SERD)

Liu, J., Zheng, S., Akerstrom, V. L., Yuan, C., Ma, Y., Zhong, Q., Zhang, C., Zhang, Q., Guo, S., Ma, P., et al. (2016) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6b00753 · Cited by 86 · see citing works

Application of Topical Phosphodiesterase 4 Inhibitors in Mild to Moderate Atopic Dermatitis

Yang, H., Wang, J., Zhang, X., Zhang, Y., Qin, Z.-L., Wang, H., & Luo, X. (2019) · JAMA Dermatology · doi:10.1001/jamadermatol.2019.0008 · Cited by 86 · see citing works

Boron Nutrition of Tobacco BY-2 Cells. V. Oxidative Damage is the Major Cause of Cell Death Induced by Boron Deprivation

Koshiba, T., Kobayashi, M., & Matoh, T. (2008) · Plant and Cell Physiology · doi:10.1093/pcp/pcn184 · Cited by 85 · see citing works

Boromycin Kills Mycobacterial Persisters without Detectable Resistance

Moreira, W., Aziz, D. B., & Dick, T. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00199 · Cited by 85 · see citing works

Asymmetric Synthesis of Protected α-Amino Boronic Acid Derivatives with an Air- and Moisture-Stable Cu(II) Catalyst

Buesking, A. W., Bacauanu, V., Cai, I. C., et al. (2014) · The Journal of Organic Chemistry · doi:10.1021/jo500300t · Cited by 84 · see citing works

Structure-Based Discovery of a Boronic Acid Bioisostere of Combretastatin A-4

Kong, Y., Grembecka, J. E., Edler, M., et al. (2005) · Chemistry & Biology · doi:10.1016/j.chembiol.2005.06.016 · Cited by 79 · see citing works

Fragment-guided design of subnanomolar β-lactamase inhibitors active in vivo

Eidam, O., Romagnoli, C., Dalmasso, G., Barelier, S., Caselli, E., Bonnet, R., Shoichet, B. K., & Prati, F. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1208337109 · Cited by 77 · see citing works

Medicinal Chemistry Projects Requiring Imaginative Structure-Based Drug Design Methods

Moitessier, N., Pottel, J., Therrien, É., Englebienne, P., Liu, Z., Tomberg, A., & Corbeil, C. R. (2016) · Accounts of Chemical Research · doi:10.1021/acs.accounts.6b00185 · Cited by 77 · see citing works

A Method for the Deprotection of Alkylpinacolyl Boronate Esters

Sun, J., Perfetti, M. T., & Santos, W. L. (2011) · The Journal of Organic Chemistry · doi:10.1021/jo200250y · Cited by 76 · see citing works

Discovery and Optimization of Boronic Acid Based Inhibitors of Autotaxin

Albers, H. M. H. G., van Meeteren, L. A., Egan, D. A., et al. (2010) · Journal of Medicinal Chemistry · doi:10.1021/jm1005012 · Cited by 76 · see citing works

Tavaborole: First Global Approval

Markham, A. (2014) · Drugs · doi:10.1007/s40265-014-0276-7 · Cited by 75 · see citing works

First-Time-in-Human Study and Prediction of Early Bactericidal Activity for GSK3036656, a Potent Leucyl-tRNA Synthetase Inhibitor for Tuberculosis Treatment

Tenero, D. M., Derimanov, G. S., Carlton, A., et al. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00240-19 · Cited by 75 · see citing works

Boronic Acid for the Traceless Delivery of Proteins into Cells

Andersen, K. A., Smith, T. P., Lomax, J. E., & Raines, R. T. (2015) · ACS Chemical Biology · doi:10.1021/acschembio.5b00966 · Cited by 73 · see citing works

Dipeptide Boronic Acid Inhibitors of Dipeptidyl Peptidase IV: Determinants of Potency and in Vivo Efficacy and Safety

Connolly, B. A., Sanford, D. G., Chiluwal, A. K., Healey, S. E., Peters, D. E., DiMare, M. T., Wu, W., Liu, Y., Maw, H. H., Zhou, Y., et al. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm800390n · Cited by 72 · see citing works

Risk of dipeptidyl peptidase-4 (DPP-4) inhibitors on site-specific cancer: A systematic review and meta-analysis

Overbeek, J. A., Bakker, M., van der Heijden, A. A. W. A., van Herk‐Sukel, M. P. P., Herings, R. M. C., & Nijpels, G. (2018) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3004 · Cited by 71 · see citing works

Spotlight on tavaborole for the treatment of onychomycosis

Finch, J. J., & Jinna, S. (2015) · Drug Design Development and Therapy · doi:10.2147/dddt.s81944 · Cited by 68 · see citing works

Dipeptidyl peptidase 4 inhibitors as novel agents in improving survival in diabetic patients with colorectal cancer and lung cancer: A Surveillance Epidemiology and Endpoint Research Medicare study

Bishnoi, R., Hong, Y., Shah, C., et al. (2019) · Cancer Medicine · doi:10.1002/cam4.2278 · Cited by 67 · see citing works

10-Boronic acid substituted camptothecin as prodrug of SN-38

Wang, L., Xie, S. P., Ma, L., et al. (2016) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2016.03.063 · Cited by 66 · see citing works

Phase I/II study of the novel proteasome inhibitor delanzomib (CEP-18770) for relapsed and refractory multiple myeloma

Vogl, D. T., Martin, T. G., Vij, R., et al. (2017) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2016.1263842 · Cited by 66 · see citing works

A Double-Blind, Placebo-Controlled Pilot Study to Evaluate the Effect of Calcium Fructoborate on Systemic Inflammation and Dyslipidemia Markers for Middle-Aged People with Primary Osteoarthritis

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Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate

Zhang, Y.-K., Plattner, J. J., Easom, E. E., et al. (2017) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b00621 · Cited by 64 · see citing works

The Long Wait for a New Drug for Human African Trypanosomiasis

Baker, C. H., & Welburn, S. C. (2018) · Trends in Parasitology · doi:10.1016/j.pt.2018.08.006 · Cited by 63 · see citing works

Sub-picomolar Inhibition of HIV-1 Protease with a Boronic Acid

Windsor, I. W., Palte, M. J., Lukesh, J. C., et al. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.8b07366 · Cited by 62 · see citing works

Talabostat

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Design of N -Benzoxaborole Benzofuran GSK8175─Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor

Chong, P. Y., Shotwell, J. B., Miller, J. F., et al. (2019) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.8b01719 · Cited by 56 · see citing works

Effects of boron supplementation of adequate and inadequate vitamin D3-containing diet on performance and serum biochemical characters of broiler chickens

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Calcium Fructoborate for Bone and Cardiovascular Health

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