The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Polymersome carriers: From self-assembly to siRNA and protein therapeutics
Open accessAbstract
Polymersomes are polymer-based vesicular shells that form upon hydration of amphiphilic block copolymers. These high molecular weight amphiphiles impart physicochemical properties that allow polymersomes to stably encapsulate or integrate a broad range of active molecules. This robustness together with recently described mechanisms for controlled breakdown of degradable polymersomes as well as escape from endolysosomes suggests that polymersomes might be usefully viewed as having structure/property/function relationships somewhere between lipid vesicles and viral capsids. Here we summarize the assembly and development of controlled release polymersomes to encapsulate therapeutics ranging from small molecule anti-cancer drugs to siRNA and therapeutic proteins.
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Citations
Cites
On the origins of morphological complexity in block copolymer surfactants
Jain, S., & Bates, F. S. (2003) · Science · doi:10.1126/science.1082193 · Cited by 1,217
Polymer vesicles in vivo: correlations with PEG molecular weight
Photos, P. J., Bacakova, L., Discher, B., Bates, F. S., & Discher, D. E. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00201-3 · Cited by 527
Self-citationBiodegradable polymersomes as a basis for artificial cells: Encapsulation, release and targeting
Meng, F., Engbers, G. H. M., & Feijen, J. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.09.026 · Cited by 227
Cited by
Chen, W., Meng, F., Cheng, R., & Zhong, Z. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.09.023 · Cited by 458
Future of the Particle Replication in Nonwetting Templates (PRINT) Technology
Xu, J., Wong, D. H. C., Byrne, J. D., Chen, K., Bowerman, C., & DeSimone, J. M. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201209145 · Cited by 208
Lee, S.-Y., Tyler, J. Y., Kim, S., Park, K., & Cheng, J.-X. (2013) · Molecular Pharmaceutics · doi:10.1021/mp4003333 · Cited by 59
Metadata
- Authors
- Christian, D. A., Cai, S., Bowen, D. M., Kim, Y., Pajerowski, J. D., & Discher, D. E.
- Venue
- European Journal of Pharmaceutics and Biopharmaceutics
- Publisher
- Elsevier BV
- Published
- 2009-03
- Volume
- 71
- Issue
- 3
- Pages
- 463-474
- ISSN
- 0939-6411 (ISSN-L)
- OpenAlex
- W1983203635
- Cited by
- 371
- References
- 3
- FWCI
- 9.70
- Type
- journal article
- Language
- en
- Open access
- green
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- Christian, D. A., Cai, S., Bowen, D. M., Kim, Y., Pajerowski, J. D., & Discher, D. E. (2009). Polymersome carriers: From self-assembly to siRNA and protein therapeutics. European Journal of Pharmaceutics and Biopharmaceutics. https://doi.org/10.1016/j.ejpb.2008.09.025
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.