Applications of PLA in modern medicine
Open accessAbstract
Polylactic acid (PLA) is a versatile biopolymer. PLA is synthesized with ease from abundant renewable resources and is biodegradable. PLA has shown promise as a biomaterial in a plethora of healthcare applications such as tissue engineering or regenerative medicine, cardiovascular implants, dental niches, drug carriers, orthopedic interventions, cancer therapy, skin and tendon healing, and lastly medical tools / equipment. PLA has demonstrated instrumental importance as a three-dimensionally (3D) printable biopolymer, which has further been bolstered by its role during the Coronavirus Disease of 2019 (Covid-19) global pandemic. As an abundant filament, PLA has created desperately needed personal protective equipment (PPE) and ventilator modifications. As polymer chemistry continues to advance, so too will the applications and continued efficacy of PLA-based modalities.
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PLA is suitable as a material for various medical uses and applications, such as surgical sutures, orthopedic and cardiovascular implants, drug delivery systems, and more.
“PLA is suitable as a material for various medical uses and applications, such as surgical sutures, orthopedic and cardiovascular implants, drug delivery systems, and more [83].”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [83]
Cites
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Poly(lactic acid) modifications
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Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review
Vach Agocsova, S., Culenova, M., Birova, I., Omanikova, L., Moncmanova, B., Danisovic, L., Ziaran, S., Bakos, D., & Alexy, P. (2023) · Materials · doi:10.3390/ma16124267 · Cited by 98 · see citing works
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- Authors
- DeStefano, V., Khan, S., & Tabada, A.
- Affiliations
- Stony Brook University (US)
- Corresponding author
- Khan, Salaar
- ORCID
- DeStefano, Vincent
- Venue
- Engineered Regeneration
- Publisher
- Elsevier BV
- Published
- 2020
- Volume
- 1
- Pages
- 76-87
- ISSN
- 2666-1381 (ISSN-L)
- PMC
- PMC7474829
- OpenAlex
- W3083599186
- Cited by
- 547
- References
- 5
- Citations by year
- 2026: 55 · 2025: 121 · 2024: 144 · 2023: 110 · 2022: 82 · 2021: 32 · 2020: 3
- FWCI
- 14.47
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Engineered Regeneration (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Health Sciences › Medicine › Surgery › Surgical Sutures and Adhesives
- Keywords
- polylactic acid, biodegradable polymers, biomaterials, tissue engineering, regenerative medicine, cardiovascular implants, dental applications, drug carriers, orthopedic implants, cancer therapy, wound healing, 3D printing, personal protective equipment, ventilator modification, COVID-19 pandemic
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