Cited by 71Air Quality and Health ImpactsIndoor Air Quality and Microbial ExposureDermatology and Skin Diseases

Association between particulate matter concentration and symptoms of atopic dermatitis in children living in an industrial urban area of South Korea

Oh, Inbo, Lee, Jiho, Ahn, Kangmo, Kim, Jihyun, Kim, Young-Min, Sun Sim, Chang, Kim, Yangho·2018·Environmental Research

Abstract

Introduction Increased exposure to particulate matter (PM) appears to increase the development of atopic diseases and allergic sensitization. This study evaluated the association between daily levels of PM with diameters less than 10µm (PM10) and PM2.5 and symptoms of atopic dermatitis (AD) in children living in an industrial urban area.Methods Indoor PM10 and PM2.5 concentrations were measured with an optical particle counter in two preschools near large industrial complexes in Ulsan, South Korea during two 6-month periods (May-October of 2012 and 2013). Twenty-one children with AD from these preschools were enrolled and observed daily for AD symptoms during the same periods. Indoor and outdoor PM concentrations were used to estimate PM exposure based on time activity patterns.Results Analysis of PM10 and PM2.5 concentrations showed that indoor and outdoor PM10 levels varied similarly throughout each 6-month period. In addition, indoor concentration of PM2.5 had high correlation with ambient outdoor concentration of PM10. Correlation analysis also indicated a significant positive correlation between the exacerbation of AD symptoms and daily mean exposure to PM10 and PM2.5. Based on a generalized linear mixed model (GLMM), PM exposure was significantly associated with the exacerbation of AD symptoms, with a maximum adjusted odds ratio (aOR) of 1.399 for a 10µg/m 3 increase of PM2.5 (95% CI: 1.216-1.610).Discussion Our findings suggest that short-term exposure to PM can exacerbate AD in young children living in an industrial urban area. PM2.5 had a stronger effect than PM10 on exacerbation of AD symptoms.

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Crossref · 10.1016/j.envres.2017.10.030

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  • Our previous epidemiologic studies showed that PM2.5 is associated with the exacerbation of AD in children.

    “Our previous epidemiologic studies also showed that PM2.5 is associated with the exacerbation of AD in children (24–26).”

    From Particulate matter causes skin barrier dysfunction. (2021) · cites this paper as [26]

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Authors
Oh, I., Lee, J., Ahn, K., Kim, J., Kim, Y.-M., Sun Sim, C., & Kim, Y.
Affiliations
  • University of Ulsan (KR)
  • Samsung Medical Center (KR)
Corresponding author
  • Kim, Jihyun
  • Kim, Young-Min
  • Kim, Yangho
Venue
Environmental Research
Publisher
Elsevier BV
Published
2018-01
Volume
160
Pages
462-468
ISSN
0013-9351 (ISSN-L)
OpenAlex
W2766558357
Cited by
71
References
20
Citations by year
2025: 9 · 2024: 5 · 2023: 10 · 2022: 7 · 2021: 15 · 2020: 12 · 2019: 10 · 2018: 3
FWCI
3.69
Type
journal article
Language
en
Open access
closed
Locations
  • Environmental Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Ministry of Environment
  • National Center for Environmental Health
Topics
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
Keywords
particulate matter, PM2.5, PM10, atopic dermatitis, children, indoor air pollution, air pollution exposure, allergic diseases, preschool children, symptom exacerbation
MeSH terms
Air Pollutants, Child, Preschool, Dermatitis, Atopic, Environmental Exposure, Environmental Monitoring, Female, Humans, Infant, Male, Air Pollution, Indoor, Particulate Matter, Republic of Korea

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