Cited by 47Environmental Toxicology and EcotoxicologyPesticide and Herbicide Environmental StudiesPesticide Exposure and Toxicity

Ecotoxicological Effects of Alpha-Cypermethrin on Freshwater Alga Chlorella Sp.: Growth Inhibition and Oxidative Stress Studies

Baruah, Prithu, Chaurasia, Neha·2020·Environmental Toxicology and Pharmacology

Abstract

Alpha-cypermethrin (ACy) is a synthetic pyrethroid insecticide commonly used in agricultural practices for controlling a broad range of insect pests particularly belonging to the order Lepidoptera and Coleoptera. The present study aims to evaluate the toxic effect of ACy on microalgae by studying its influence on Chlorella sp. According to our knowledge, this is the first detailed study of ACy toxicity on microalgae. Significant growth inhibition of Chlorella sp. was observed at high ACy concentration (6-48 mg L-1) during the entire 96 h bioassay. The 96 h median effective concentration (EC 50) of ACy was estimated to be 11.00 mg L-1. Flow cytometry analysis showed an enhanced generation of reactive oxygen species (ROS) and intracellular lipid accumulation after 96 h exposure to 11.00 mg L-1 of ACy. Further, the same ACy concentration showed a significant decrease in photosynthetic pigment content and an increase in antioxidant enzyme activity and malondialdehyde (MDA) content in Chlorella sp.

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Crossref · 10.1016/j.etap.2020.103347

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  • According to research on alpha-cypermethrin, the lipophilic pyrethroid pesticide toxicity of chlorella exhibits acute and chronic toxicity to the human body, causes insomnia and mental disorders, and may cause DNA mutations.

    “According to research on alpha-cypermethrin, the lipophilic pyrethroid pesticide toxicity of chlorella, it is found that toxic reaction to the human body than other pesticides (nausea, vomiting, dizziness), exhibits acute and chronic toxicity, causes insomnia and mental disorders, and may cause DNA mutations [112].”

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Authors
Baruah, P., & Chaurasia, N.
Affiliations
North Eastern Hill University (IN)
Corresponding author
Chaurasia, Neha
Venue
Environmental Toxicology and Pharmacology
Publisher
Elsevier BV
Published
2020-05
Volume
76
Pages
103347
ISSN
1382-6689 (ISSN-L)
OpenAlex
W3003997888
Cited by
47
References
83
Citations by year
2026: 4 · 2025: 8 · 2024: 8 · 2023: 10 · 2022: 10 · 2021: 6 · 2020: 1
FWCI
2.70
Type
journal article
Language
en
Open access
closed
Locations
  • Environmental Toxicology and Pharmacology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Department of Science and Technology, Ministry of Science and Technology, India
  • University Grants Commission
Topics
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
  • Physical Sciences › Environmental Science › Pollution › Pesticide and Herbicide Environmental Studies
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Pesticide Exposure and Toxicity
Keywords
alpha-cypermethrin, pyrethroid insecticides, Chlorella, microalgae toxicity, growth inhibition, oxidative stress, reactive oxygen species, lipid peroxidation, malondialdehyde, photosynthetic pigments, antioxidant enzymes, freshwater algae, EC50
MeSH terms
Chlorella, Dose-Response Relationship, Drug, Pyrethrins, Reactive Oxygen Species, Oxidative Stress

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