The DOI matches its Crossref record; 70 of the 71 references it cites were found in a registry or an index.
Alcohol misuse in bipolar disorder. A systematic review and meta-analysis of comorbidity rates
Abstract
AIMS: To assess the comorbidity rates of alcohol use disorders (AUDs) in bipolar disorder (BD) and to explore possible sources of heterogeneity. METHODS: Studies were identified through database searches. Meta-analytic techniques were employed to aggregate data on lifetime comorbidity and to explore possible sources of heterogeneity. Funnel plots were used to detect publication bias. RESULTS: In clinical studies, AUDs affected more than one in three subjects with BD. Significant heterogeneity was found, which was largely explained by the geographical location of study populations and gender ratio of participants. AUDs affected more than one in five women and two in five men. CONCLUSION: AUDs are highly prevalent in BD. Our study revealed a substantial heterogeneity across studies. Further research including control groups is needed. Patients with BD should be assessed for current and previous AUDs.
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“and metabolic disturbance may be present from illness onset.136”
From The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness (2019) · cites this paper as [136]
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“Previous systematic reviews and meta-analyses have found that lifetime alcohol use disorders are known to more frequently affect people with schizophrenia [24] and people with bipolar disorders [25,26].”
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“The frequent coexistence of alcohol use and psychiatric disorders has been documented in the scientific literature [13–17].”
Metadata
- Authors
- Di Florio, A., Craddock, N., & van den Bree, M.
- Affiliations
- Cardiff University (GB)
- ORCID
- Craddock, N.
- Venue
- European Psychiatry
- Publisher
- Cambridge University Press (CUP)
- Published
- 2014-03
- Volume
- 29
- Issue
- 3
- Pages
- 117-124
- ISSN
- 0924-9338 (ISSN-L)
- 1778-3585
- OpenAlex
- W1974477361
- Cited by
- 117
- References
- 71
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 6 · 2023: 13 · 2022: 11 · 2021: 11 · 2020: 13 · 2019: 9 · 2018: 5 · 2017: 8 · 2016: 9 · 2015: 7 · 2014: 8
- FWCI
- 1.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
- Funders
- Medical Research Council (MR/L010305/1, MR/K023233/1)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- bipolar disorder, alcoholism, alcohol abuse, psychiatric comorbidity, lifetime prevalence, sex differences, publication bias, heterogeneity sources
- MeSH terms
- Alcoholism, Bipolar Disorder, Humans, Comorbidity
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