In vitro screening of essential oil from young and mature leaves of Artemisia scoparia compared to its major constituents for free radical scavenging activity
Abstract
The present study investigated the chemical characterization, and antioxidant activity of essential oil hydrodistilled from young and mature leaves of Artemisia scoparia. GC-MS analyses revealed a monoterpenoid nature (64-67%) with 44 and 31 constituents in young and mature leaves oil, respectively. The oil from young leaf contained greater amount of oxygenated compounds. Beta-myrcene (24.13%) and p-cymene (27.06%) were the major constituents in young and mature leaves oil, respectively. A. scoparia leaf oils (25-200 microg/ml) exhibited a strong 2,2-diphenyl-1-picrylhydrazyl radical scavenging capacity and antioxidant activity against hydroxyl radical and hydrogen peroxide. However, the activities of major constituent monoterpenes, beta-myrcene and p-cymene, were less. In general, the DPPH radical scavenging and antioxidant activity was in the order: mature leaf oil > young leaf oil > beta-myrcene > p-cymene.
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Ageratum scoparia young and mature leaf oils displayed high hydroxyl radical scavenging; main constituents β-myrcene and p-cymene had much less activity than oils; mature leaf oils were more effective antioxidants than young leaf oils by DPPH.
“The oils from young and mature leaves of Ageratum scoparia Waldst. & Kit. displayed a high degree of hydroxyl radical scavenging activity. However, the scavenging activity of principle constituents, β-myrcene and p-cymene, was very less compared to that of oils. The same authors [83] also evaluated the antioxidant activity of the samples by the DPPH method and also reported less activity of the”
From Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review (2010) · cites this paper as [83]
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Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review
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“The same authors [83] also evaluated the antioxidant activity of the samples by the DPPH method and also reported less activity of the main constituents of the oils than the essential oils, nevertheless the mature leaf oils were more effective as antioxidants than young leaf oils.”
Method
- Authors
- Singh, H. P., Kaur, S., Mittal, S., Batish, D. R., & Kohli, R. K.
- Affiliations
- Panjab University (IN)
- Corresponding author
- Singh, Harminder Pal
- Venue
- Food and Chemical Toxicology
- Publisher
- Elsevier BV
- Published
- 2010-04
- Volume
- 48
- Issue
- 4
- Pages
- 1040-1044
- ISSN
- 0278-6915 (ISSN-L)
- OpenAlex
- W2064527784
- Cited by
- 47
- References
- 31
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 5 · 2023: 2 · 2022: 5 · 2021: 3 · 2020: 3 · 2019: 4 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 3 · 2014: 3 · 2013: 3 · 2012: 1
- FWCI
- 4.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food and Chemical Toxicology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- Artemisia scoparia, essential oils, young leaves, mature leaves, antioxidant activity, free radical scavenging, myrcene, p-cymene, monoterpenes, DPPH radical scavenging, hydroxyl radicals, hydrogen peroxide, leaf age
- MeSH terms
- Aging, Chlorophyll, Hydrogen Peroxide, Gas Chromatography-Mass Spectrometry, Plant Oils, Plant Proteins, Free Radical Scavengers, Thiobarbituric Acid Reactive Substances, Plant Leaves, Artemisia
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