The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
The lipin protein family: Dual roles in lipid biosynthesis and gene expression
Open accessAbstract
The prevalence of obesity in the western world has focused attention on factors that influence triglyceride biosynthesis, storage, and utilization. Members of the lipin protein family have a newly discovered enzymatic role in triglyceride and phospholipid biosynthesis as a phosphatidate phosphatase, and also act as an inducible transcriptional coactivator in conjunction with peroxisome proliferator‐activated receptor γ (PPARγ) coactivator‐1α and PPARα. Through these activities, the founding member of the family, lipin‐1, influences lipid metabolism and glucose homeostasis in diverse tissues including adipose tissue, skeletal muscle, and liver. The physiological roles of lipin‐2 and lipin‐3 are less well defined, but are likely to carry out similar functions in glycerolipid biosynthesis and gene expression in a distinct tissue distribution.
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Cites
Adipocyte differentiation from the inside out
Rosen, E. D., & MacDougald, O. A. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2066 · Cited by 2,607
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
Lecker, S. H., Jagoe, R. T., Gilbert, A., Gomes, M., Baracos, V., Bailey, J., Price, S. R., Mitch, W. E., & Goldberg, A. L. (2004) · The FASEB Journal · doi:10.1096/fj.03-0610com · Cited by 1,539
Unger, R. H. (2002) · Annual Review of Medicine · doi:10.1146/annurev.med.53.082901.104057 · Cited by 875
Phospholipid biosynthesis program underlying membrane expansion during B-lymphocyte differentiation
Fagone, P., Sriburi, R., Ward-Chapman, C., Frank, M., Wang, J., Gunter, C., Brewer, J. W., & Jackowski, S. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m608175200 · Cited by 93
Cited by
The obesogen tributyltin induces abnormal ovarian adipogenesis in adult female rats
de Araújo, J. F. P., Podratz, P. L., Sena, G. C., Merlo, E., Freitas-Lima, L. C., Ayub, J. G. M., Pereira, A. F. Z., Santos-Silva, A. P., Miranda-Alves, L., Silva, I. V., et al. (2018) · Toxicology Letters · doi:10.1016/j.toxlet.2018.06.1068 · Cited by 65
Metadata
- Authors
- Reue, K., & Zhang, P.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2007-11-20
- Volume
- 582
- Issue
- 1
- Pages
- 90-96
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2062005522
- Cited by
- 209
- References
- 4
- FWCI
- 7.62
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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