Adipocyte differentiation from the inside out

Prevalence of Overweight and Obesity in the United States, 1999-2004

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The Wnt Signaling Pathway in Development and Disease

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Prevalence of Overweight and Obesity in the United States

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Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment

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Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

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Smad transcription factorsPreprint

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Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ

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Transcriptional regulation of adipogenesisPreprint

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Inhibition of Adipogenesis by Wnt Signaling

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C/EBPα induces adipogenesis through PPARγ: a unified pathwayPreprint

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ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism.Preprint

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Cross-Regulation of C/EBPα and PPARγ Controls the Transcriptional Pathway of Adipogenesis and Insulin Sensitivity

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TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation

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Adipokines: molecular links between obesity and atheroslcerosis

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Regulation of osteoblastogenesis and bone mass by Wnt10b

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PPAR γ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

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Adipose Tissue Selective Insulin Receptor Knockout Protects against Obesity and Obesity-Related Glucose Intolerance

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Communicating with Hedgehogs

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Wnt signaling in osteoblasts and bone diseases

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Defective adipocyte differentiation in mice lacking the C/EBPβ and/or C/EBPδ gene

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Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

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Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

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The Role of C/EBP Genes in Adipocyte Differentiation

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Regulation of Wnt Signaling during Adipogenesis

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PPAR γ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

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The Forkhead Transcription Factor Foxo1 Regulates Adipocyte Differentiation

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ

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ADD1/SREBP1 activates PPARγ through the production of endogenous ligand

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Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium.

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Evidence for a role of developmental genes in the origin of obesity and body fat distribution

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Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes

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The role of MAPKs in adipocyte differentiation and obesity

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Myostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis

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A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2

George, S., Rochford, J. J., Wolfrum, C., Gray, S. L., Schinner, S., Wilson, J. C., Soos, M. A., Murgatroyd, P. R., Williams, R. M., Acerini, C. L., et al. (2004) · Science · doi:10.1126/science.1096706 · Cited by 559 · see citing works

Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis

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Function of GATA Transcription Factors in Preadipocyte-Adipocyte Transition

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Adipose Development: From Stem Cell to Adipocyte

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Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice

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Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes.

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Suppression of body fat accumulation in myostatin-deficient mice

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Bone Morphogenetic Protein-2 Causes Commitment and Differentiation in C3Hl0T1/2 and 3T3 Cells

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CCAAT/enhancer-binding protein β is required for mitotic clonal expansion during adipogenesis

Tang, Q.-Q., Otto, T. C., & Lane, M. D. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337434100 · Cited by 485 · see citing works

Mice Lacking Paternally Expressed Pref-1/Dlk1 Display Growth Retardation and Accelerated Adiposity

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Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation

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Regulation of Peroxisome Proliferator–Activated Receptor-γ Activity by Mammalian Target of Rapamycin and Amino Acids in Adipogenesis

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Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

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SRC-1 and TIF2 Control Energy Balance between White and Brown Adipose Tissues

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Rosiglitazone Causes Bone Loss in Mice by Suppressing Osteoblast Differentiation and Bone Formation

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Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage

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Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis

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Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse

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Biological control through regulated transcriptional coactivators

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Wnt10b Inhibits Development of White and Brown Adipose Tissues

Longo, K. A., Hahn, W. S., Kang, S., Gerin, I., Chiang, S.-H., Lucas, P. C., Opp, M. R., & MacDougald, O. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402937200 · Cited by 372 · see citing works

Testosterone Inhibits Adipogenic Differentiation in 3T3-L1 Cells: Nuclear Translocation of Androgen Receptor Complex with β-Catenin and T-Cell Factor 4 May Bypass Canonical Wnt Signaling to Down-Regulate Adipogenic Transcription Factors

Singh, R., Artaza, J. N., Taylor, W. E., Braga, M., Yuan, X., Gonzalez-Cadavid, N. F., & Bhasin, S. (2006) · Endocrinology · doi:10.1210/en.2004-1649 · Cited by 369 · see citing works

PPARγ knockdown by engineered transcription factors: exogenous PPARγ2 but not PPARγ1 reactivates adipogenesisPreprint

Ren, D., Collingwood, T. N., Rebar, E. J., Wolffe, A. P., & Camp, H. S. (2002) · Genes & Development · doi:10.1101/gad.953802 · Cited by 362 · see citing works

Adipogenesis: forces that tip the scales

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Transforming Growth Factor-β Inhibits Adipocyte Differentiation by Smad3 Interacting with CCAAT/Enhancer-binding Protein (C/EBP) and Repressing C/EBP Transactivation Function

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Role of Krüppel-like Factor 15 (KLF15) in Transcriptional Regulation of Adipogenesis

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C/EBPα is required for differentiation of white, but not brown, adipose tissue

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Msx2 Promotes Osteogenesis and Suppresses Adipogenic Differentiation of Multipotent Mesenchymal Progenitors

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Roles of Autocrine TGF-β Receptor and Smad Signaling in Adipocyte Differentiation

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Transcription coactivator TRAP220 is required for PPARγ2-stimulated adipogenesis

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Peroxisome-proliferator-activated receptor γ suppresses Wnt/β-catenin signalling during adipogenesis

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The Krüppel-like Factor KLF2 Inhibits Peroxisome Proliferator-activated Receptor-γ Expression and Adipogenesis

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Role of Peroxisome Proliferator-Activated Receptor-γ in Maintenance of the Characteristics of Mature 3T3-L1 Adipocytes

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Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation

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Role of CREB in Transcriptional Regulation of CCAAT/Enhancer-binding Protein β Gene during Adipogenesis

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Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic mice.

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Selective disruption of PPARγ2 impairs the development of adipose tissue and insulin sensitivity

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Cellularity of adipose depots in six strains of genetically obese mice

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Cyclin D1 Inhibits Peroxisome Proliferator-activated Receptor γ-mediated Adipogenesis through Histone Deacetylase Recruitment

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Hedgehog signaling plays a conserved role in inhibiting fat formation

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De novo adipogenesis in mice at the site of injection of basement membrane and basic fibroblast growth factor

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Sonic hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiation

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Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor–1 (Pref-1)

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A Role for C/EBPβ in Regulating Peroxisome Proliferator-activated Receptor γ Activity during Adipogenesis in 3T3-L1 Preadipocytes

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Microarray Analyses during Adipogenesis: Understanding the Effects of Wnt Signaling on Adipogenesis and the Roles of Liver X Receptor α in Adipocyte Metabolism

Ross, S. E., Erickson, R. L., Gerin, I., DeRose, P. M., Bajnok, L., Longo, K. A., Misek, D. E., Kuick, R. D., Hanash, S., Atkins, K. B., et al. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.16.5989-5999.2002 · Cited by 255 · see citing works

Activated Liver X Receptors Stimulate Adipocyte Differentiation through Induction of Peroxisome Proliferator-Activated Receptor γ Expression

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Interaction between GATA and the C/EBP Family of Transcription Factors Is Critical in GATA-Mediated Suppression of Adipocyte Differentiation

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Genetic Analysis of Adipogenesis through Peroxisome Proliferator-activated Receptor γ Isoforms

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The Nuclear Receptor Corepressors NCoR and SMRT Decrease Peroxisome Proliferator-activated Receptor γ Transcriptional Activity and Repress 3T3-L1 Adipogenesis*

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The Kru¨ppel-like Factor KLF15 Regulates the Insulin-sensitive Glucose Transporter GLUT4

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A Nuclear Receptor Atlas: 3T3-L1 Adipogenesis

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Regional differences of insulin action in adipose tissue: insights from <i>in vivo</i> and <i>in vitro</i> studies

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Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes

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