Inositol transport proteins

Predicting transmembrane protein topology with a hidden markov model: application to complete genomes11Edited by F. Cohen

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Phylogeny.fr: robust phylogenetic analysis for the non-specialist

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Bipolar Disorder

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Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation

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The SLC2 (GLUT) family of membrane transporters

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Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

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Seed Development and Germination

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Intracellular Organic Osmolytes: Function and Regulation

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Autophagy: Pathways for Self-Eating in Plant Cells

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Tonicity-responsive enhancer binding protein, a Rel-like protein that stimulates transcription in response to hypertonicity

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The sodium/glucose cotransport family SLC5

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The SLC2 family of facilitated hexose and polyol transporters

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Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model

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Myo-inositol and beyond – Emerging networks under stress

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Cloning of the cDNa for a Na+/myo-inositol cotransporter, a hypertonicity stress protein.

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Inositol signaling and plant growth

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Inositol signaling and plant growth

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Identification of a mammalian H+‐myo‐inositol symporter expressed predominantly in the brain

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The Vitis vinifera sugar transporter gene family: phylogenetic overview and macroarray expression profiling

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Lithium and bipolar mood disorder: the inositol-depletion hypothesis revisited

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The Arabidopsis ATP-binding Cassette Protein AtMRP5/AtABCC5 Is a High Affinity Inositol Hexakisphosphate Transporter Involved in Guard Cell Signaling and Phytate Storage

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Developing Seeds of Arabidopsis Store Different Minerals in Two Types of Vacuoles and in the Endoplasmic Reticulum

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Identification of a Novel Na+/myo-Inositol Cotransporter

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Transcription of the Sodium/myo-Inositol Cotransporter Gene Is Regulated by Multiple Tonicity-responsive Enhancers Spread over 50 Kilobase Pairs in the 5′-Flanking Region

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The Sugar Transporter Inventory of Tomato: Genome-Wide Identification and Expression Analysis

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Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae

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Na+/myo-inositol symporters and Na+/H+-antiport in Mesembryanthemum crystallinum

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The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3): molecular cloning and localization to chromosome 21

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The Monosaccharide Transporter Gene Family in Arabidopsis and Rice: A History of Duplications, Adaptive Evolution, and Functional Divergence

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myo-Inositol: A Newly Identified Nonnitrogenous Osmoregulatory Molecule in Mammalian Brain

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Kinetics and specificity of the renal Na+/myo-inositol cotransporter expressed in Xenopus Oocytes

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Myo-Inositol-Dependent Sodium Uptake in Ice Plant1

Nelson, D. E., Koukoumanos, M., & Bohnert, H. J. (1999) · PLANT PHYSIOLOGY · doi:10.1104/pp.119.1.165 · Cited by 116 · see citing works

Comparison of Three Amyloid Assembly Inhibitors: The Sugar scyllo-Inositol, the Polyphenol Epigallocatechin Gallate, and the Molecular Tweezer CLR01

Sinha, S., Du, Z., Maiti, P., Klärner, F., Schrader, T. H., Wang, C., & Bitan, G. (2012) · ACS Chemical Neuroscience · doi:10.1021/cn200133x · Cited by 112 · see citing works

Routes to the Tonoplast: The Sorting of Tonoplast Transporters in Arabidopsis Mesophyll Protoplasts

Wolfenstetter, S., Wirsching, P., Dotzauer, D., Schneider, S., & Sauer, N. (2012) · The Plant Cell · doi:10.1105/tpc.111.090415 · Cited by 109 · see citing works

Inositol methyl tranferase from a halophytic wild rice, Porteresia coarctata Roxb. (Tateoka): regulation of pinitol synthesis under abiotic stress

Sengupta, S., Patra, B., Ray, S., & Majumder, A. L. (2008) · Plant Cell & Environment · doi:10.1111/j.1365-3040.2008.01850.x · Cited by 98 · see citing works

Trans-Golgi Network-Located AP1 Gamma Adaptins Mediate Dileucine Motif-Directed Vacuolar Targeting in Arabidopsis

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Strategies for acquiring the phospholipid metabolite inositol in pathogenic bacteria, fungi and protozoa: making it and taking it

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Functional and Physiological Characterization of Arabidopsis INOSITOL TRANSPORTER1 , a Novel Tonoplast-Localized Transporter for myo -Inositol

Schneider, S., Beyhl, D., Hedrich, R., & Sauer, N. (2008) · The Plant Cell · doi:10.1105/tpc.107.055632 · Cited by 92 · see citing works

Arabidopsis INOSITOL TRANSPORTER4 Mediates High-Affinity H+ Symport of Myoinositol across the Plasma Membrane

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Plant Phosphoinositides and Intracellular Signaling

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Brain Inositol Is a Novel Stimulator for Promoting Cryptococcus Penetration of the Blood-Brain Barrier

Liu, T.-B., Kim, J.-C., Wang, Y., Toffaletti, D. L., Eugenin, E., Perfect, J. R., Kim, K. J., & Xue, C. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003247 · Cited by 89 · see citing works

Drug Resistance in Leishmaniasis: Current Drug-Delivery Systems and Future Perspectives

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Loss of Murine Na+/myo-Inositol Cotransporter Leads to Brain myo-Inositol Depletion and Central Apnea

Berry, G. T., Wu, S., Buccafusca, R., Ren, J. T., Gonzales, L. W., Ballard, P. L., Golden, J. A., Stevens, M. J., & Greer, J. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m213176200 · Cited by 88 · see citing works

scyllo-Inositol, Preclinical, and Clinical Data for Alzheimer’s Disease

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Cytokinins in seed development and germination.

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Localization and rapid regulation of Na+/myo-inositol cotransporter in rat kidney.

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Importance of organic osmolytes for osmoregulation by renal medullary cells.

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Role of an Expanded Inositol Transporter Repertoire in Cryptococcus neoformans Sexual Reproduction and Virulence

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Sodium/myo‐inositol cotransporter‐1 is essential for the development and function of the peripheral nerves

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KCNQ1, KCNE2, and Na + -Coupled Solute Transporters Form Reciprocally Regulating Complexes That Affect Neuronal Excitability

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Regulated exocytosis of an H+/myo‐inositol symporter at synapses and growth cones

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Arabidopsis INOSITOL TRANSPORTER2 Mediates H + Symport of Different Inositol Epimers and Derivatives across the Plasma Membrane

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SMIT2 mediates all myo-inositol uptake in apical membranes of rat small intestine

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Inhibition of the High Affinity Myo-Inositol Transport System A Common Mechanism of Action of Antibipolar Drugs?

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Contributions in astrocytes of SMIT1/2 and HMIT to myo-inositol uptake at different concentrations and pH

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Cloning, localization and expression analysis of vacuolar sugar transporters in the CAM plant Ananas comosus (pineapple)

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Sodium/myo-inositol cotransporter 1 and myo-inositol are essential for osteogenesis and bone formation

Dai, Z., Chung, S. K., Miao, D., Lau, K. S., Chan, A. W. H., & Kung, A. W. (2010) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.240 · Cited by 61 · see citing works

In vivo osmoregulation of Na/myo-inositol cotransporter mRNA in rat kidney medulla.

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Silencing of TonEBP/NFAT5 Transcriptional Activator by RNA Interference

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Inositol Metabolism in Yeasts

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The high affinity inositol transport system – implications for the pathophysiology and treatment of bipolar disorder

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Subcellular distribution of phytin in the endosperm of developing castor bean: a possibility for its synthesis in the cytoplasm prior to deposition within protein bodies

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A cold‐induced myo‐inositol transporter‐like gene confers tolerance to multiple abiotic stresses in transgenic tobacco plants

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New human sodium/glucose cotransporter gene (KST1): identification, characterization, and mutation analysis in ICCA (infantile convulsions and choreoathetosis) and BFIC (benign familial infantile convulsions) families

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Annotation of Human Chromosome 21 for Relevance to Down Syndrome: Gene Structure and Expression Analysis

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Polyol profiles in Down syndrome. myo-Inositol, specifically, is elevated in the cerebrospinal fluid.

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Evaluation of expression and function of the H+/myo-inositol transporter HMIT

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Phosphoinositide deficiency due to inositol depletion is not a mechanism of lithium action in brain

Berry, G. T. (2004) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2004.02.002 · Cited by 49 · see citing works

An exploratory analysis on gene-environment interactions for Parkinson disease

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Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells

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<i>Candida albicans</i> Uses Multiple Mechanisms To Acquire the Essential Metabolite Inositol during Infection

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Characterization of the null murine sodium/myo-inositol cotransporter 1 (Smit1 or Slc5a3) phenotype: Myo-inositol rescue is independent of expression of its cognate mitochondrial ribosomal protein subunit 6 (Mrps6) gene and of phosphatidylinositol levels in neonatal brain

Buccafusca, R., Venditti, C. P., Kenyon, L. C., Johanson, R. A., Bockstaele, E. V., Ren, J. T., Pagliardini, S., Minarcik, J. C., Golden, J. A., Coady, M. J., et al. (2008) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2008.05.008 · Cited by 43 · see citing works

In vivo brain myo -inositol levels in children with Down syndrome

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Determination of transport stoichiometry for two cation‐coupled myo‐inositol cotransporters: SMIT2 and HMIT

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Up‐regulation of hypertonicity‐activated myo‐inositol transporter SMIT1 by the cell volume‐sensitive protein kinase SGK1

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SUT Sucrose and MST Monosaccharide Transporter Inventory of the Selaginella Genome

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Two Major Inositol Transporters and Their Role in Cryptococcal Virulence

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myo-Inositol Uptake Is Essential for Bulk Inositol Phospholipid but Not Glycosylphosphatidylinositol Synthesis in Trypanosoma brucei

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Expression and functionality of the Na+/myo-inositol cotransporter SMIT2 in rabbit kidney

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The Structural Organization of the Human Na+/Myo-inositol Cotransporter (SLC5A3) Gene and Characterization of the Promoter

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Activators of protein kinase A and of protein kinase C inhibit MDCK cell myo-inositol and betaine uptake.

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Sodium/myo-Inositol Transporters: Substrate Transport Requirements and Regional Brain Expression in the TgCRND8 Mouse Model of Amyloid Pathology

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Amino acid depletion activates TonEBP and sodium-coupled inositol transport

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Osmoregulation of Liver Cell Function: Signalling, Osmolytes and Cell Heterogeneity

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Augmentation of lithium's behavioral effect by inositol uptake inhibitors

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Down syndrome with and without dementia: An in vivo proton Magnetic Resonance Spectroscopy study with implications for Alzheimer's disease

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ESCRT-Independent Surface Receptor And Transporter Protein Degradation By The ILF PathwayPreprint

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Organic Solutes in Cereals Under Abiotic Stress

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