Cited by 195Endometriosis Research and TreatmentEpigenetics and DNA MethylationPlant and fungal interactions

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Aberrant expression of deoxyribonucleic acid methyltransferases DNMT1, DNMT3A, and DNMT3B in women with endometriosis

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Wu, Yan, Strawn, Estil, Basir, Zainab, Halverson, Gloria, Guo, Sun-Wei·2007·Fertility and Sterility

DOI 10.1016/j.fertnstert.2006.05.077

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Abstract

Objective Since endometriosis is a persistent disease with substantial gene dysregulation, there must be cellular memory of some sort that constitutes a unique cell identity for endometriotic cells. Epigenetic regulation, especially through DNA methylation, is a flexible, yet stable, mechanism for maintaining such a cellular memory. The aim of this study was to determine gene expression levels of DNMT1, DNMT3A, and DNMT3B, the three genes coding for DNA methyltransferases that are responsible for methylation.Design Cross-sectional measurements of gene expression levels of DNMT1, DNMT3A, and DNMT3B on endometriotic tissue.Setting Academic.Patient(s) Seventeen patients with laparoscopically confirmed endometriosis and 8 healthy women who underwent tubal sterilization who were free of endometriosis were recruited for the study.Intervention(s) Epithelial cells were harvested from tissue samples by laser capture microdissection and messenger RNA abundance was measured by quantitative real-time reverse transcription-polymerase chain reaction.Main outcome measure(s) The expression levels of these genes in epithelial cells from 13 ectopic endometrial tissue samples, 10 eutopic endometrial tissue samples taken from women with endometriosis, and 8 normal endometrial tissue samples from women without endometriosis.Result(s) The genes DNMT1, DNMT3A, and DNMT3B were over-expressed in the ectopic endometrium as compared with normal control subjects or the eutopic endometrium of women with endometriosis, and their expression levels were correlated positively with each other.Conclusion(s) The aberrant expression of these genes suggests that aberrant methylation may be rampant in endometriosis. This also provides a strong piece of evidence that endometriosis ultimately may be an epigenetic disease.

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DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
Okano, M., Bell, D. W., Haber, D. A., & Li, E. (1999) · Cell · doi:10.1016/s0092-8674(00)81656-6 · Cited by 6,143
The fundamental role of epigenetic events in cancer
Jones, P. A., & Baylin, S. B. (2002) · Nature Reviews Genetics · doi:10.1038/nrg816 · Cited by 5,648
CpG-rich islands and the function of DNA methylation
Bird, A. P. (1986) · Nature · doi:10.1038/321209a0 · Cited by 3,777
Endometriosis
Giudice, L. C., & Kao, L. C. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17403-5 · Cited by 3,166
Epigenetic Reprogramming in Mammalian Development
Reik, W., Dean, W., & Walter, J. (2001) · Science · doi:10.1126/science.1063443 · Cited by 3,078
DNA methylation and human disease
Robertson, K. D. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1655 · Cited by 2,864
Dating the Endometrial Biopsy
Rw, N., Hertig, A. T., & Rock, J. A. (1950) · Fertility and Sterility · doi:10.1016/s0015-0282(16)30062-0 · Cited by 2,845
DNA methylation in health and disease
Robertson, K. D., & Wolffe, A. P. (2000) · Nature Reviews Genetics · doi:10.1038/35049533 · Cited by 1,077
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
Rhee, I., Bachman, K. E., Park, B. H., Jair, K.-W., Yen, R.-W. C., Schuebel, K. E., Cui, H., Feinberg, A. P., Lengauer, C., Kinzler, K. W., et al. (2002) · Nature · doi:10.1038/416552a · Cited by 1,039
De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells
Lei, H., Oh, S. P., Okano, M., Jüttermann, R., Goss, K. A., Jaenisch, R., & Li, E. (1996) · Development · doi:10.1242/dev.122.10.3195 · Cited by 816

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Show all 52 references

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Szczepańska, M., Mostowska, A., Wirstlein, P. K., Lianeri, M., Marianowski, P., Skrzypczak, J., & Jagodziński, P. P. (2011) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2011.02.003 · Cited by 20
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Zou, Y., Liu, F., Wang, L., Guo, J.-B., Yang, B., Wan, X., Wang, F., He, M., & Huang, O. (2016) · Gene · doi:10.1016/j.gene.2016.12.011 · Cited by 16
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Sultan, S., & AlMalki, S. (2023) · Epigenetics · doi:10.1080/15592294.2023.2201714 · Cited by 15
Epigenetics and Chronic Diseases: An Overview
Smith, R. G., & Mill, J. S. (2011) · Springer eBooks · doi:10.1007/978-1-84882-644-1_1 · Cited by 15
Endometriosis and ovarian cancer risk, an epigenetic connection
Brunty, S., Mitchell, B. L., Zgheib, N. B., & Santanam, N. (2020) · Annals of Translational Medicine · doi:10.21037/atm-20-2449 · Cited by 15
Lovastatin Reduces Stemness via Epigenetic Reprograming of BMP2 and GATA2 in Human Endometrium and Endometriosis.
Taghizadeh, M., & Noruzinia, M. (2017) · PubMed Central · doi:10.22074/cellj.2016.3894 · Cited by 15
Histone Acetylation And Methylation
An, W. (2007) · Springer eBooks · doi:10.1007/1-4020-5466-1_16 · Cited by 15
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Tamura, K., Yoshie, M., Kusama, K., & Tsuru, A. (2025) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12663 · Cited by 18
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Liao, Z., Monsivais, D., & Matzuk, M. M. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.10.036 · Cited by 16
Management of first-trimester complications in the emergency department
Murtaza, U. I., Ortmann, M. J., Mando‐Vandrick, J., & Lee, A. S. D. (2013) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp120069 · Cited by 13
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Aberrant expression of histone deacetylase 8 in endometriosis and its potential as a therapeutic target
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WU, Y., ZHANG, M., Zhang, X., Xu, Z., & Jin, W.-G. (2016) · Oncology Letters · doi:10.3892/ol.2016.4512 · Cited by 13
Self-citation
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Nicotine attenuates global genomic DNA methylation by influencing DNMTs gene expression in human endometrial stromal cells
Zal, F., Yarahmadi, A., Totonchi, H., Barazesh, M., & Sarabi, M. M. (2020) · Genes and Environment · doi:10.1186/s41021-020-0144-5 · Cited by 11
Temporal Modulation of DNA Methylation and Gene Expression in Monolayer and 3D Spheroids of Dental Pulp Stem Cells during Osteogenic Differentiation: A Comparative Study
Raik, S., Thakur, R., Rattan, V., Kumar, N., Pal, A., & Bhattacharyya, S. (2022) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-022-00485-x · Cited by 11
Nrf2−/− regulated lung DNA demethylation and CYP2E1 DNA methylation under PM2.5 exposure
Wu, M.-J., Jiang, M.-H., Ding, H., Tang, S., Li, D.-C., Pi, J., Zhang, R., Chen, W., Chen, R., Zheng, Y., et al. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1144903 · Cited by 9
MicroRNAs and the pathogenesis of endometriosis
Neubauer, C., Kiesel, L., & Götte, M. (2012) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.5301/je.2012.9226 · Cited by 10
Regulation of HAND2 Expression by LncRNA HAND2-AS1 in Ovarian Endometriosis Involving DNA Methylation
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Histone deacetylase inhibitors as therapeutics for endometriosis
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Self-citation
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Gerkowicz, S. A., Curtis, S. W., Knight, A. K., Cobb, D. O., Spencer, J. B., Conneely, K. N., Terrell, M. L., Marcus, M., & Smith, A. K. (2020) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-020-01695-9 · Cited by 9
Polymorphic variants of DNMT3A and the risk of endometriosis
Szczepańska, M., Mostowska, A., Wirstlein, P. K., Malejczyk, J., Płoski, R., Skrzypczak, J., & Jagodziński, P. P. (2012) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2012.09.003 · Cited by 12
Child with Beckwith-Wiedemann syndrome born after assisted reproductive techniques to an human immunodeficiency virus serodiscordant couple
Kuentz, P., Bailly, A., Faure, A.-C., Blagosklonov, O., Amiot, C., Bresson, J.-L., & Roux, C. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.04.030 · Cited by 9
DNMT1 and DNMT3B gene variants and their association with endometriosis in South Indian women
Veena, K. V., Siddamalla, S., Deenadayal, M., Shivaji, S., & Bhanoori, M. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06877-x · Cited by 9
ATM expression is attenuated by promoter hypermethylation in human ovarian endometriotic stromal cells
Hirakawa, T., Nasu, K., Aoyagi, Y., Takebayashi, K., Zhu, R., & Narahara, H. (2019) · Molecular Human Reproduction · doi:10.1093/molehr/gaz016 · Cited by 9
Genome-Wide Methylation Analysis of DNMT3B Gene Isoforms Revealed Specific Methylation Profiles in Breast Cell Lines
Plourde, K. V., Labrie, Y., Ouellette, G., Pouliot, M., & Durocher, F. (2016) · Epigenomics · doi:10.2217/epi-2016-0013 · Cited by 9
MiR-17-5p promoter methylation regulated by DNA methyltransferase 3 beta (DNMT3B) expedites endometriosis via the Krüppel-like factor 12 (KLF12)/Wnt/β-catenin axis
Yang, X., Tao, Y., Jin, O., Lai, J., & Yang, X. (2023) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2023.103974 · Cited by 8
The Epigenetics of Endometriosis
Guo, S. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-388415-2.00022-6 · Cited by 8
Self-citation
Endometriosis research using capture microdissection techniques: Progress and future applications
Zhao, L., Gu, C., Huang, K., Han, W., Fu, M., & Meng, Y. (2016) · Biomedical Reports · doi:10.3892/br.2016.758 · Cited by 8
GRIK1‐AS1 deficiency accelerates endometriosis progression by boosting DNMT1‐dependent SFRP1 promoter methylation in endometrial stromal cells
Liu, W., Hu, B., Wang, X., Huang, E., Chen, X., & Chen, L. (2023) · The Journal of Gene Medicine · doi:10.1002/jgm.3557 · Cited by 8
Dual inhibition of AKT and ERK1/2 pathways restores the expression of progesterone Receptor-B in endometriotic lesions through epigenetic mechanisms
Dutta, S., Lee, J., Banu, S. K., & Arosh, J. A. (2024) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2024.112290 · Cited by 7
Laser Capture Microdissection
Tayade, C., Edwards, A. K., & Bidarimath, M. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-394445-0.00048-5 · Cited by 7
The luteal phase
Toner, J. P. (2008) · CRC Press eBooks · doi:10.3109/9780203092934-44 · Cited by 7
Epigenetic Regulation Interplays with Endometriosis Pathogenesis in Low-Birth-Weight Patients via the Progesterone Receptor B–VEGF-DNMT1 Axis
Setiawan, A., Anwar, R., Syamsunarno, M. R. A. A., Mose, J. C., Santoso, B. I., Maskoen, A. M., Permadi, W., Setiabudiawan, B., Dhamayanti, M., & Hidayat, Y. M. (2023) · Diagnostics · doi:10.3390/diagnostics13122085 · Cited by 6
Research Highlights: Highlights from the latest articles in epigenomics of endometriosis
Peltomäki, P., & Bützow, R. C. (2011) · Epigenomics · doi:10.2217/epi.11.96 · Cited by 6
Aberrant Hoxa10 gene methylation as a mechanism for endosulfan-induced implantation failures in rats
Milesi, M. M., Lorenz, V., & Varayoud, J. (2022) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2022.111576 · Cited by 6
Endocrine Disruptors: Genetic, Epigenetic, and Related Pathways
Ansari, R. A., Alfuraih, S., Shekh, K., Omidi, Y., Javed, S., & Saghir, S. A. (2023) · Wiley eBooks · doi:10.1002/9781119896258.ch3 · Cited by 6
The Association between Deoxyribonucleic Acid Hypermethylation in Intron VII and Human Leukocyte Antigen-C ∗ 07 Expression in Patients with Endometriosis
Zhao, W., Lei, L., Chen, R., Zhang, Y., Chang, L., & Cheng, J. (2023) · International Journal of Clinical Practice · doi:10.1155/2023/2291156 · Cited by 5
A multi-omics informatics approach for identifying molecular mechanisms and biomarkers in clinical patients with endometriosis
Akter, S., Wilshire, G., Davis, J. W., Bromfield, J. J., Crowder, S., Joshi, T., Pelch, K. E., Schust, D. J., Meng, A., Barrier, B. F., et al. (2017) · IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · doi:10.1109/bibm.2017.8218003 · Cited by 5
DNA methylation and DNA methyltransferase (DNMT1) activity pattern in endometrial carcinoma.
Romanek-Piva, K., Gałczyński, K., Adamiak, A., Rechberger, T., & Postawski, K. (2016) · Ginekologia Polska · doi:10.17772/gp/60556 · Cited by 5
NF-κB as an Inflammatory Biomarker in Thin Endometrium: Predictive Value for Live Birth in Recurrent Implantation Failure
Kalı, Z., Karlı, P., Çağiran, F. T., Kirici, P., & Ege, S. (2025) · Diagnostics · doi:10.3390/diagnostics15141762 · Cited by 4
Epigenetic Approaches in Neuroblastoma Disease Pathogenesis
Caputi, F. F., Candeletti, S., & Romualdi, P. (2017) · InTech eBooks · doi:10.5772/intechopen.69566 · Cited by 4
Endometriotic mesenchymal stem cells promote the fibrosis process of endometriosis through paracrine TGF ‐β1 mediated RASAL1 inhibition
Feng, Y., Han, D., & Tan, B. (2023) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.15851 · Cited by 4
Imprinted and DNA methyltransferase gene expression in the endometrium during the pre- and peri-implantation period in cattle
O’Doherty, A., O’Shea, L. C., Sandra, O., Lonergan, P., Fair, T., & Forde, N. (2016) · Reproduction Fertility and Development · doi:10.1071/rd16238 · Cited by 4
Reproductive disease epigenetics
Colón-Díaz, M., Jaramillo, A. J., Soto, E. Y., & Elosegui, P. M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823928-5.00027-x · Cited by 4
The emerging role of epigenetics and miRNAs in endometriosis
Rosser, M., Haris, P. I., Ankrett, D. N., & Konje, J. C. (2011) · Expert Review of Obstetrics & Gynecology · doi:10.1586/eog.11.32 · Cited by 4
Polychlorinated Biphenyls Alter Estrogen Receptor β-mediated Epigenetic Regulation, Promoting Endometriosis
Park, Y., Sung, N., Kim, E., Jeong, J., Sim, J., Park, M. J., Lydon, J. P., Guan, X., & Han, S. J. (2025) · Endocrinology · doi:10.1210/endocr/bqaf146 · Cited by 3
Intracrine oestrogen production and action in breast cancer: An epigenetic focus
Knower, K. C., To, S. Q., & Clyne, C. D. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.01.009 · Cited by 3
DNA methylation of P2X3 receptor gene encoded pain marker protein in endometriosis
Ocktariyana, O., Hestiantoro, A., Febri, R. R., & Asmarinah, A. (2019) · Journal of Physics Conference Series · doi:10.1088/1742-6596/1246/1/012031 · Cited by 3
HOX Genes and Endometriosis
Kulp, J. L., Çakmak, H., & Taylor, H. S. (2011) · Wiley eBooks · doi:10.1002/9781444398519.ch18 · Cited by 3
Study on the mechanism of USP7 promoting endometriosis by regulating DNMT1 deubiquitination level
Gao, X., Liu, L., Liu, X., Shen, Y., & Fan, Y. (2025) · Biochemistry and Cell Biology · doi:10.1139/bcb-2024-0301 · Cited by 3
Hormonal Dysregulation and Neuroinflammation in Endometriosis: Convergent Druggable Pathways
Olteanu, I.-L., Pușcașu, C., Andrei, C., & Zanfirescu, A. (2026) · Current Issues in Molecular Biology · doi:10.3390/cimb48050528 · Cited by 2
Endometrial Determinism of Endometriosis: An Unnecessary Adjunct to Retrograde Menstruation
Habiba, M. A., Guo, S., & Benagiano, G. (2024) · Current Obstetrics and Gynecology Reports · doi:10.1007/s13669-024-00378-x · Cited by 3
Self-citation
Molecular Pathology and Therapy of Endometriosis: Revisited
Suresh, P., Venkatesh, T., Rajan, T., & Tsutsumi, R. (2013) · Andrology & Gynecology Current Research · doi:10.4172/2327-4360.1000105 · Cited by 4
The Endometrium in Adenomyosis
Habiba, M. A., & Benagiano, G. (2015) · Springer eBooks · doi:10.1007/978-3-319-13012-5_6 · Cited by 2
Derivative of Stevioside; CPUK02; Restores ESR1 Gene Methylation in MDA-MB 231
Khazayel, S., Mokarram, P., Mohammadi, Z., Ramezani, F., & Dayong, Z. (2018) · Europe PMC (PubMed Central) · doi:10.22034/apjcp.2018.19.8.2117 · Cited by 2
Metabolic remodeling of endometriosis microenvironment: Energy stress and immune evasion
Yang, P., Wang, T., Liu, W., Miao, Y., Zhu, Y., & Sun, J. (2026) · iScience · doi:10.1016/j.isci.2026.116592 · Cited by 1
DNA Methylation may be a testicular plateau adaptation in Tibetan pig
Zhao, Y., Tian, M., Cheng, Z., Wang, J., & Ren, Z. (2021) · Journal of Applied Animal Research · doi:10.1080/09712119.2021.1882465 · Cited by 1
Towards gene therapy of endometriosis
Shubina, A., Kiselev, A., Egorova, A., & Сергеевич, Б. В. (2012) · Journal of obstetrics and women s diseases · doi:10.17816/jowd613148-158 · Cited by 1
Pathogenesis: Epigenetics
Guo, S. (2011) · Wiley eBooks · doi:10.1002/9781444398519.ch7 · Cited by 1
Self-citation
Promoter Methylation Levels of Progesterone Receptor-B (PR-B) and Expression of mRNA DNA Methyltransferase-1 (DNMT-1) In Menstrual Blood Patients with EndometriosisPreprint
Madjid, T. H., Saputra, M., & Rowawi, R. (2023) · Research Square · doi:10.21203/rs.3.rs-3301543/v1 · Cited by 1
The emerging role of epigenetics in the aetiology of endometriosis.
Rosser, M. (2011) · DMU Open Research Archive (De Montfort University)
Potential New Drugs for Endometriosis: Experimental Evidence
Nasu, K., Kawano, Y., Nishida, M., Tsuno, A., Yuge, A., Abe, W., Kai, K., Okamoto, M., & Narahara, H. (2014) · Springer eBooks · doi:10.1007/978-4-431-54421-0_16
Medical Management of Endometriosis
Rizk, B., Nawar, M. G., Rizk, C. B., & Rizk, D. B. (2008) · Cambridge University Press eBooks · doi:10.1017/cbo9780511547287.036
Genetics and epigenetics in human cancer
Lv, J., Liu, H., Liu, H., Wu, Q., & Zhang, Y. (2014) · Cancer Genetics and Epigenetics · doi:10.5376/cge.2014.02.0001
Review article: IMPRINTING GENES ASSOCIATED WITH ENDOMETRIOSIS
Kobayashi, H. (2014)
Association between DNMT3L polymorphic variants and the risk of endometriosis-associated infertility
Mostowska, A., Szczepańska, M., Wirstlein, P. K., Skrzypczak, J., & Jagodziński, P. P. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4626
Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Biociências
Meyer, J. L. (2011)
Translational Aspects of the Endometriosis Epigenome
Colón-Caraballo, M., & Flores, I. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812215-0.00023-6
Etiopatogenia da Endometriose
Bragança, C. M. C. (2013) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.34626/2fxe-we94
Molecular Mechanisms Underlying Adolescent Endometriosis and Advancements in Medical Management
Mama, S. T. (2020) · Springer eBooks · doi:10.1007/978-3-030-52984-0_5
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Additional file 1 of The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract
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Additional file 3 of The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract
Zhou, Y., Gu, B., Brichant, G., Singh, J. P., Yang, H., Chang, H., Zhao, Y., Cheng, C., Liu, Z.-W., Alderman, M. H., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19689328
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Velho, R. V., & Mechsner, S. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-27757-3.00006-7

Authors: Wu, Y., Strawn, E., Basir, Z., Halverson, G., & Guo, S.-W.
Affiliations: Medical College of Wisconsin (US)
Corresponding author: Guo, Sun-Wei
ORCID: Wu, Yan
Guo, Sun-Wei
Venue: Fertility and Sterility
Publisher: Elsevier BV
Published: 2007-01
Volume: 87
Issue: 1
Pages: 24-32
ISSN: 0015-0282 (ISSN-L)
DOI: 10.1016/j.fertnstert.2006.05.077
OpenAlex: W2095392967
Cited by: 193
References: 52
Citations by year: 2026: 4 · 2025: 8 · 2024: 6 · 2023: 21 · 2022: 8 · 2021: 6 · 2020: 6 · 2019: 8 · 2018: 7 · 2017: 7 · 2016: 13 · 2015: 9 · 2014: 16 · 2013: 8 · 2012: 18
FWCI: 6.69
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 5625 d)
Locations: Fertility and Sterility (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Plant and fungal interactions
Keywords: endometriosis, DNA methyltransferases, DNMT1, DNMT3A, DNMT3B, DNA methylation, epigenetic regulation, ectopic endometrium, eutopic endometrium, gene expression, cellular memory, epigenetic disorders
MeSH terms: DNA (Cytosine-5-)-Methyltransferase 1, DNA Methyltransferase 3A, DNA Methyltransferase 3B, Adult, DNA (Cytosine-5-)-Methyltransferases, Endometriosis, Endometrium, Female, Humans, Middle Aged, Tissue Distribution, Gene Expression

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Aberrant expression of deoxyribonucleic acid methyltransferases DNMT1, DNMT3A, and DNMT3B in women with endometriosis

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