Cited by 289Endometriosis Research and TreatmentHealth Systems, Economic Evaluations, Quality of LifeEctopic Pregnancy Diagnosis and Management

The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.

Economic burden of endometriosis

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Abstract

Objective To comprehensively review and evaluate the direct costs of endometriosis.Design and setting We systematically reviewed studies published since 1990, and conducted an analysis of publicly available national databases (Healthcare Cost and Utilization Project and National Ambulatory Medical Care Survey/National Hospital Ambulatory Medical Care Survey) in the United States. We assessed: [1] the overall economic impact of endometriosis; [2] the direct costs associated with specific treatments; and [3] the indirect costs of endometriosis associated with reduced work productivity.Results Of 13 published studies meeting inclusion criteria, 11 (85%) addressed direct costs, a few studies addressed outpatient costs or indirect costs, and no study quantified the economic impact among adolescents. Direct endometriosis-related costs were considerable and appeared driven by hospitalizations. Our database analysis found: [1] as endometriosis-related hospital length of stay steadily declined from 1993 to 2002, per-patient cost increased 61%; [2] adolescents (aged 10-17 years) had endometriosis-related hospitalizations; [3] approximately 50% of >600,000 endometriosis-related ambulatory patient visits involved specialist care; and [4] females 23 years old or younger constituted >20% of endometriosis-related outpatient visits.Conclusions Health economic information for endometriosis is scarce, limiting our understanding of its overall economic impact. Nevertheless, the literature and other available data suggest that endometriosis places a considerable burden on patients and society.

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Crossref · 10.1016/j.fertnstert.2006.06.015

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  1. Kovacs, 2002, Conference Report from the 49th Annual Meeting of the Society for Gynecologic Investigation, Medscape Ob/Gyn Womens Health, 7
  2. Luciano, 1992, Endoscopic treatment of endometriosis-associated infertility, J Reprod Med, 37, 573
  3. Heinrichs, 1998, Human issues and medical economics of endometriosis, J Reprod Med, 43, 299
  4. Medical economics Thomson healthcare. Redbook: Pharmacy’s fundamental reference, 2005 edition.

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Metadata

Authors
Gao, X., Outley, J., Botteman, M., Spalding, J., Simon, J. A., & Pashos, C. L.
Affiliations
  • Abt Global (United States) (US)
  • Pharmerit (United States) (US)
  • George Washington University (US)
Corresponding author
Gao, Xin
Venue
Fertility and Sterility
Publisher
Elsevier BV
Published
2006-12
Volume
86
Issue
6
Pages
1561-1572
ISSN
0015-0282 (ISSN-L)
OpenAlex
W2098584612
Cited by
289
References
54
Citations by year
2026: 6 · 2025: 11 · 2024: 14 · 2023: 14 · 2022: 20 · 2021: 6 · 2020: 13 · 2019: 8 · 2018: 13 · 2017: 16 · 2016: 16 · 2015: 16 · 2014: 14 · 2013: 14 · 2012: 23
FWCI
1.86
Type
journal article
Language
en
Open access
Locations
  • Fertility and Sterility (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
  • Health Sciences › Medicine › Obstetrics and Gynecology › Ectopic Pregnancy Diagnosis and Management
Keywords
endometriosis, economic burden, direct costs, indirect costs, work productivity loss, hospital costs, length of hospital stay, outpatient visits, adolescent endometriosis, outpatient care, treatment costs
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Employment, Endometriosis, Female, Hospitalization, Humans, Middle Aged, United States, Comorbidity, Health Care Costs, Cost of Illness, Pelvic Pain

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