Cited by 137Endometriosis Research and TreatmentMinimally Invasive Surgical TechniquesGynecological conditions and treatments

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Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a multicenter, randomized, controlled trial

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Soto, Enrique, Luu, Thanh Ha, Liu, Xiaobo, Magrina, Javier F., Wasson, Megan N., Einarsson, Jon I., Cohen, Sarah L., Falcone, Tommaso·2017·Fertility and Sterility

DOI 10.1016/j.fertnstert.2016.12.033

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Abstract

Objective To determine whether the use of the robot for surgical treatment of endometriosis is better than traditional laparoscopy in terms of operative length, perioperative parameters, and quality of life outcomes. Design Multicenter, randomized clinical trial. Setting University teaching hospitals. Patient(s) Women aged >18 years with suspected endometriosis who elected to undergo surgical management. Intervention(s) Randomization to conventional or robot-assisted laparoscopic removal of endometriosis. Main outcome measure(s) The primary outcome measured was operative time. Secondary outcomes were perioperative complications and quality of life. Result(s) The mean operative time for robotic vs. laparoscopic surgery for endometriosis was 106.6 ± 48.4 minutes vs. 101.6 ± 63.2 minutes. There were no differences in blood loss, intraoperative or postoperative complications, or rates of conversion to laparotomy in the two arms. Both groups reported significant improvement on condition-specific quality of life outcomes at 6 weeks and 6 months. Conclusion(s) There were no differences in perioperative outcomes between robotic and conventional laparoscopy. Clinical trial registration number NCT01556204.

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Authors: Soto, E., Luu, T. H., Liu, X., Magrina, J. F., Wasson, M. N., Einarsson, J. I., Cohen, S. L., & Falcone, T.
Affiliations: Cleveland Clinic (US)
Mayo Clinic in Arizona (US)
Brigham and Women's Hospital (US)
Corresponding author: Falcone, Tommaso
ORCID: Soto, Enrique
Liu, Xiaobo
Magrina, Javier F.
Wasson, Megan N.
Einarsson, Jon I.
Cohen, Sarah L.
Falcone, Tommaso
Venue: Fertility and Sterility
Publisher: Elsevier BV
Published: 2017-04
Volume: 107
Issue: 4
Pages: 996-1002.e3
ISSN: 0015-0282 (ISSN-L)
DOI: 10.1016/j.fertnstert.2016.12.033
OpenAlex: W2589501886
Cited by: 137
References: 30
Citations by year: 2026: 8 · 2025: 14 · 2024: 18 · 2023: 25 · 2022: 20 · 2021: 14 · 2020: 13 · 2019: 15 · 2018: 7 · 2017: 1
FWCI: 11.42
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1882 d)
Locations: Fertility and Sterility (publishedVersion)
PubMed (publishedVersion)
Funders: Cleveland Clinic
Topics: Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
Keywords: endometriosis, robot-assisted laparoscopic surgery, conventional laparoscopy, operative time, perioperative complications, conversion to open surgery, blood loss, quality of life, endometriosis surgery
MeSH terms: Adult, Endometriosis, Female, Hospitals, University, Humans, Laparoscopy, Postoperative Complications, Prospective Studies, Quality of Life, Time Factors, United States, Blood Loss, Surgical, Treatment Outcome, Operative Time, Conversion to Open Surgery, Robotic Surgical Procedures

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Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a multicenter, randomized, controlled trial

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