Fibroids and medical therapy: Bridging the gap from selective progesterone receptor modulators to gonadotropin-releasing hormone antagonist
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SPRMs are not an option for endometriosis because they induce progesterone modulator-associated endometrial changes (PAECs) in ectopic foci and their efficacy is limited.
“among new drugs, selective progesterone receptor modulators (SPRMs) are not an option as they induce progesterone modulator-associated endometrial changes (PAECs) in ectopic foci and their efficacy is limited [89,90,91].”
From Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review (2021) · cites this paper as [91]
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Cites
Uterine fibroid management: From the present to the future
Donnez, J., & Dolmans, M.-M. (2016) · Human Reproduction Update · doi:10.1093/humupd/dmw023 · Cited by 780 · see citing works
Self-citationElagolix for Heavy Menstrual Bleeding in Women with Uterine Fibroids
Schlaff, W. D., Ackerman, R. T., Al-Hendy, A. A., Archer, D. F., Barnhart, K. T., Bradley, L. D., Carr, B. R., Feinberg, E. C., Hurtado, S. M., Kim, J. H., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa1904351 · Cited by 207 · see citing works
Gonadotropin-releasing hormone antagonist (linzagolix): A new therapy for uterine adenomyosis
Donnez, O., & Donnez, J. (2020) · Fertility and Sterility · doi:10.1016/j.fertnstert.2020.04.017 · Cited by 58 · see citing works
Self-citationLiver injury and ulipristal acetate: an overstated tragedy?
Donnez, J. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.06.044 · Cited by 51 · see citing works
Self-citationDonnez, J., & Dolmans, M.-M. (2020) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2020.05.017 · Cited by 50 · see citing works
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Donnez, J., & Dolmans, M.-M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10051085 · Cited by 182 · see citing works
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- Authors
- Donnez, J., & Dolmans, M.-M.
- Affiliations
- Cliniques Universitaires Saint-Luc (BE)
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2020-10
- Volume
- 114
- Issue
- 4
- Pages
- 739-741
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W3080983417
- Cited by
- 20
- References
- 5
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 3
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Digital Access to Libraries (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Health and Contraception
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
- Keywords
- uterine fibroids, medical therapy, selective progesterone receptor modulators, GnRH antagonist, surgical avoidance, hysterectomy, myomectomy, uterine fibroid treatment
- MeSH terms
- Female, Humans, Leiomyoma, Gonadotropin-Releasing Hormone, Receptors, Progesterone, Uterine Neoplasms, Randomized Controlled Trials as Topic
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