Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 101

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Comparative evaluation of rosmarinic acid, methyl rosmarinate and pedalitin isolated from Rabdosia serra (MAXIM.) HARA as inhibitors of tyrosinase and α-glucosidase

Lin, Lianzhu, Dong, Yi, Zhao, Haifeng, Wen, Lingrong, Yang, Bao, Zhao, Mouming·2011·Food Chemistry
DOI 10.1016/j.foodchem.2011.05.039
Open this paper in CoChat — free account

Abstract

Rabdosia serra has been used in traditional Chinese medicine for centuries. In order to illustrate the pharmaceutical activity of R. serra as hypoglycaemic and skin-whitening agents, rosmarinic acid (confirmed as the major compound in R. serra), methyl rosmarinate and pedalitin isolated from R. serra were evaluated for their inhibitory effects and mechanisms on tyrosinase and α-glucosidase. The inhibitory effects on both tyrosinase and α-glucosidase were in decreasing order, pedalitin>methyl rosmarinate>rosmarinic acid. The IC50 values for the tyrosinase and α-glucosidase activity inhibited by pedalitin were 0.28 and 0.29mM, respectively. Both rosmarinic acid and methyl rosmarinate were considered as noncompetitive inhibitors of tyrosinase, while pedalitin was suggested to be a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid was found to be a competitive inhibitor, whereas both methyl rosmarinate and pedalitin were considered as mixed-type inhibitors.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.foodchem.2011.05.039

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 1 references

Research works printed but not linked: 24

  1. Adisakwattana, 2009, A series of cinnamic acid derivatives and their inhibitory activity on intestinal alpha-glucosidase, Journal of Enzyme Inhibition and Medicinal Chemistry, 24, 1194, 10.1080/14756360902779326 · DOI
  2. Brownlee, 2005, The pathobiology of diabetic complications – A unifying mechanism, Diabetes, 54, 1615, 10.2337/diabetes.54.6.1615 · DOI · Paper page
  3. Chen, 2000, Abietane quinones from Rabdosia serra, Chinese Chemical Letters, 11, 229
  4. Ding, 2010, Antioxidant and antimelanogenic properties of rosmarinic acid methyl ester from Origanum vulgare, Food Chemistry, 123, 254, 10.1016/j.foodchem.2010.04.025 · DOI
  5. Gong, 2005, Inhibitory effect of ferulic acid on oxidation of l-DOPA catalyzed by mushroom tyrosinase, Chinese Journal Of Chemical Engineering, 13, 771
  6. Heim, 2002, Flavonoid antioxidants: Chemistry, metabolism and structure–activity relationships, Journal of Nutritional Biochemistry, 13, 572, 10.1016/S0955-2863(02)00208-5 · DOI
  7. Iwai, 2004, In vitro antioxidative effects and tyrosinase inhibitory activities of seven hydroxycinnamoyl derivatives in green coffee beans, Journal of Agricultural and Food Chemistry, 52, 4893, 10.1021/jf040048m · DOI
  8. Kang, 2004, Rosmarinic acid as a tyrosinase inhibitors from Salvia miltiorrhiza, Natural Product Sciences, 10, 80
  9. Kerem, 2006, Antioxidant activity and inhibition of α-glucosidase by trans-resveratrol, piceid, and a novel trans-stilbene from the roots of Israeli Rumex bucephalophorus L, Journal of Agricultural and Food Chemistry, 54, 1243, 10.1021/jf052436+ · DOI
  10. Kim, 2010, Antioxidant activity and α-glucosidase inhibitory potential of onion (Allium cepa L.) extracts, Food science and Biotechnology, 19, 159, 10.1007/s10068-010-0022-1 · DOI
  11. Kim, 2005, Tyrosinase inhibitors from natural and synthetic sources: Structure, inhibition mechanism and perspective for the future, Cellular and Molecular Life Sciences, 62, 1707, 10.1007/s00018-005-5054-y · DOI
  12. Kim, 2002, Oxyresveratrol and hydroxystilbene compounds, Journal of Biological Chemistry, 277, 16340, 10.1074/jbc.M200678200 · DOI
  13. Kwon, 2006, Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension, Asia Pacific Journal of Clinical Nutrition, 15, 107
  14. Lee, 2002, Tyrosinase inhibitors of Pulsatilla cernua root-derived materials, Journal of Agricultural and Food Chemistry, 50, 1400, 10.1021/jf011230f · DOI
  15. Lin, 2011, Assessment of in vitro antioxidant capacity of stem and leaf extracts of Rabdosia serra (MAXIM.) HARA and identification of the major compound, Food Chemistry, 126, 54, 10.1016/j.foodchem.2010.10.060 · DOI
  16. Liu, 2010, Rapid analysis of 27 Components of Isodon serra by LC–ESI-MS-MS, Chromatographia, 72, 265, 10.1365/s10337-010-1642-6 · DOI
  17. Riley, 1997, Melanin, International Journal of Biochemistry & Cell Biology, 29, 1235, 10.1016/S1357-2725(97)00013-7 · DOI
  18. Scott, 2002, Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation, Journal of cell science, 115, 2349, 10.1242/jcs.115.11.2349 · DOI
  19. Wang, 2010, α-Glucosidase and α-amylase inhibitory activities of guava leaves, Food Chemistry, 123, 6, 10.1016/j.foodchem.2010.03.088 · DOI
  20. Xiao, 2001, Abietane diterpenes from Rabdosia serra (maxim) hara, Journal of Chemical Research-S, 4, 148, 10.3184/030823401103169315 · DOI
  21. Xie, 2003, Inhibitory effects of some flavonoids on the activity of mushroom Tyrosinase, Biochemistry (Moscow), 68, 487, 10.1023/A:1023620501702 · DOI
  22. Yang, 2008, Optimization of tyrosinase inhibition activity of ultrasonic-extracted polysaccharides from longan fruit pericarp, Food Chemistry, 110, 294, 10.1016/j.foodchem.2008.01.067 · DOI
  23. Yong, 1990, Agaricus bisporus Metapotyrosinase: Preparation, characterization, and conversion to mixed-metal derivatives of the binuclear site, Biochemistry, 29, 9684, 10.1021/bi00493a025 · DOI
  24. Zhang, 2005, Distinct immunosuppressive effect by Isodon serra extracts, International Immunopharmacology, 5, 1957, 10.1016/j.intimp.2005.06.016 · DOI

Cited by

See all 101

Metadata

Authors
Lin, L., Dong, Y., Zhao, H., Wen, L., Yang, B., & Zhao, M.
Venue
Food Chemistry
Publisher
Elsevier BV
Published
2011-12
Volume
129
Issue
3
Pages
884-889
ISSN
0308-8146
DOI
10.1016/j.foodchem.2011.05.039
Cited by
101
References
1
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Funders
  • National Natural Science Foundation of China (31071638)
  • Eleventh Five-year National Key Technology R&D Program of China (2007BAK36B05)
  • Science and Technology Planning Project of Guangdong Province (2009B011300004)
  • Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-EW-J-28)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Comparative evaluation of rosmarinic acid, methyl rosmarinate and pedalitin isolated from Rabdosia serra (MAXIM.) HARA as inhibitors of tyrosinase and α-glucosidase. https://app.cochat.ai/papers/10.1016/j.foodchem.2011.05.039
The paper
Lin, L., Dong, Y., Zhao, H., Wen, L., Yang, B., & Zhao, M. (2011). Comparative evaluation of rosmarinic acid, methyl rosmarinate and pedalitin isolated from Rabdosia serra (MAXIM.) HARA as inhibitors of tyrosinase and α-glucosidase. Food Chemistry. https://doi.org/10.1016/j.foodchem.2011.05.039

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.