Influence of the uronic acid composition on the gastroprotective activity of alginates from three different genus of Tunisian brown algae
Abstract
Alginates from three genus of Tunisian brown algae were isolated and characterized by size exclusion chromatography and Solid-state NMR spectroscopy. Alginate from Padina pavonica (APP) had the highest molecular weight (Mw) with 147,000g/mol while it was 85,000g/mol for alginate from Cystoseira compressa (ACC) and 58,000g/mol for alginate from Dictyopteris membranaceae (ADM). The mannuronate (M) to guluronate (G) ratios were estimated from spectral deconvolution of the 13 C CP/MAS spectra and the results has shown that all the extracts are mannuronic acid-rich alginates with M/G ratio increased in the order ADM - ACC - APP. An interesting gastroprotective effect was observed for the extracts; ADM and ACC exhibited the highest inhibition of gastric lesions, at 50mg/kg, with 83.41% and 75.39% respectively. Otherwise, it has been shown that the gastroprotective effect of alginates depends mainly on their uronic acid composition.
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Alginates from brown algae species such as Macrocystis, Ascophyllum and Laminaria are used for ice cream, energetic or sweet bars, salad dressings, and syrups.
“An example is the use of industrially extracted alginates of brown algae species, such as Macrocystis, Ascophyllum and Laminaria, for the elaboration of ice cream, to avoid the formation of large amounts of ice and give them a creamy and smooth texture.”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [104]
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The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value
Gomez-Zavaglia, A., Prieto Lage, M. A., Jimenez-Lopez, C., Mejuto, J. C., & Simal-Gandara, J. (2019) · Antioxidants · doi:10.3390/antiox8090406 · Cited by 280 · see citing works
- Authors
- Ammar, H. H., Lajili, S., Sakly, N., Cherif, D., Rihouey, C., Le Cerf, D., Bouraoui, A., & Majdoub, H.
- Affiliations
- University of Monastir (TN)
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Majdoub, Hatem
- Venue
- Food Chemistry
- Publisher
- Elsevier BV
- Published
- 2018-01
- Volume
- 239
- Pages
- 165-171
- ISSN
- 0308-8146 (ISSN-L)
- OpenAlex
- W2628359918
- Cited by
- 47
- References
- 34
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 6 · 2021: 7 · 2020: 13 · 2019: 5 · 2018: 3
- FWCI
- 6.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- alginate, brown algae, gastroprotection, Padina pavonica, Cystoseira compressa, molecular weight, gastric lesions, marine polysaccharides
- MeSH terms
- Phaeophyceae, Alginates, Hexuronic Acids, Magnetic Resonance Spectroscopy, Uronic Acids, Glucuronic Acid
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